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The map label for this gene is tmcA [H]

Identifier: 85059699

GI number: 85059699

Start: 2935301

End: 2937352

Strand: Reverse

Name: tmcA [H]

Synonym: SG1721

Alternate gene names: 85059699

Gene position: 2937352-2935301 (Counterclockwise)

Preceding gene: 85059700

Following gene: 85059694

Centisome position: 70.42

GC content: 67.2

Gene sequence:

>2052_bases
GTGACTTCCCTGCCGCCGCCCTGGCTGGCCTGCCTGCGTGCAGAAACGGCGGCAATGAAACGAGCCGGCGTGCGGCGTTT
GCTGGTGATTAGCGGCGCGTCTGACTGGTGTGCCCAACAGGCGGCGGCGCTTGGCGACGCCCTTGACGGCGACTGGCTAT
GGGTGGGGGAGCAAAGCGAATGCGGTACTGGTAGCCGCCCGGCGGCGCTGAAAATCCTGCTCGGTCGTGAGTTCCTGCAT
GCGGTGTTCGATGCCCGTCAATCGCTGGCGGTGGATACGTTGGCGGCGCTGGCCGGTACGCTGGTGGCGGGCAGCTGGTT
GGTGCTGCTGGTGCCGCCCTGGTCGCGTTGGCCCCGGTTGCCGGATGGCGATTCGCTACGCTGGAGTGAACAGCTACAAC
CGATCGCAACGCCGCACTTCACCCGCTATTTTCGCGCTGCGTTGTCGGCGGATCCGGCGGTGGCGCTGCTGCGCCAGGAT
CGCGCGCCGCAGATAACGCTTCTGGTGTCCCGCCTGCCGTGGCATCCCCCCGTCCCCGGCCGACCCACCGCCGATCAGGG
CCGGCTTTTGCGCCGGTTGGCGCAGGCAAAGCCCGGCATCTATGTGATGATTGCGCCGCGCGGCCGCGGCAAATCGGCGC
TGGCCGGCATGTTCGCCCAGACGCTTGATGATGCCTGCTGTATTACCGCGCCCACCAAAGCCGCTGTGGACATCTTGCGC
CGCTACGCGGGCCCGGGCGCTCCCTTTTTCGCCCCCGATGCGCTATTGGCCCGCTGCCGGGCGGGGATGAGCGCCCGCTG
GCTGCTGGTGGATGAAGCCGCCGCGCTGCCCTTACCGCTGTTGCGTCAATTGATGGGGTATTTTTCCCATGTGCTGCTGA
CCACTACCGTCGCGGGGTATGAGGGCACCGGGCGCGGATTCCTGCTGAAGTTTTGCGAAACGCTACCGTGTTGGTGCCCG
CTCAGGCTGGATGCGCCGTTGCGCTGGGCGGCGAATGATCCGCTGGAGCGCTGGCTGACCGAAACGCTCATGCTTGAGGA
CGCCGAGGTAGTGGCCCCTGCCGGCAAAGGCGCGCCGCAGAATACGGATGCGGGCGCCGCAGGGGCAGGGCGATGGCGCA
TCGGTAAAGTCGGCGCCCAGACGTGGCGGCGCCAGCCCGCGGCGCGGCAGGCTTTTTATCAATTATTGACCCGTGCCCAT
TACCGTACTTCCCCTATCGATCTACGCCGATTGCTGGATGCACCCGGTATGTCCTTCTTTACCGCGCACCACCACCGCCA
GCTTATGGCGGGTCTGTGGCTGGTAGAGGAAGGGGGGTTGACGTCACGCCTCGCGCACGACGTCTGGGCGGGCTACCGCC
GGCCGCCGGGCAGTCTGGTCGCGCAATCGCTGGCGGCGCACGGGAGCGCCTGGCGAGCGCCGCGGCTGCGCTCCCGGCGA
ATCAGCCGTATCGCCGTGACGCCTACAGAGCGTCGACGCGGTATCGGGCTAGAGCTGATTGCTAAGGCGGCAGAGCAGGC
TGCCGGTGAGGGGCGCGATTTTCTGTCGGTCAGTTTTGGTTATACCGCCGCGCTGTGGCGTTTTTGGCAGCGGGCGGGCT
TCAAACTGGTACGAATGGGGACACACCGCGAGGCCAGCAGCGGCCTGTACAGCGCCATGGCGCTGCTGCCCCTGAGTGAC
GCGGGGCGTAAACTGACGCTGCGGGCGGCGAACGGTTTCGAGCGCGATTGCCGGCTGGCGGCCGGCGAGCAACAGGATCT
TAGGATGGAGGATTGGCGCTGCCTGGCGGGTTTTGCGTTCGCCCAGCGACCGCCGGAAGCCTGCCGCAGCGCGCTGACCC
GACTTATTAACCGCAGCACGCTGCCGCTACCGGCGTTGCGCCTGTGGTTGACACAGCCCATGCCGGACGCCACGCTGGTG
GCACGGTTGGCGCTCAGCGGGAAAAAAGCGCTCTGGCGGCACTGGCGGCAGGAAACGGCGGCGGCCATGGCGGCGGCAGA
TGCGCGCTTAACGCACCGCTGGCAACGGATCTGTCAGCAGCAGGCGCGCTAA

Upstream 100 bases:

>100_bases
TTGGTAGGTACGGTGCTCGGGGTGGCATTGTTCCGCGGCGTGCCGGTGGGGCCGCTCATTGCCGCTGGGCTGCTGTCGCT
GCTCGTGGGCAACACCTGAG

Downstream 100 bases:

>100_bases
AACCGAGGGCGTTATGGCTTTTTCGGCCAGTCGTCTTCCTCATCCCACTGCGCGTTATTGTCCCGATGCGGCGGCAACTC
GGGGCGATTTTTCAGATAGC

Product: putative acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 682

Protein sequence:

>683_residues
MTSLPPPWLACLRAETAAMKRAGVRRLLVISGASDWCAQQAAALGDALDGDWLWVGEQSECGTGSRPAALKILLGREFLH
AVFDARQSLAVDTLAALAGTLVAGSWLVLLVPPWSRWPRLPDGDSLRWSEQLQPIATPHFTRYFRAALSADPAVALLRQD
RAPQITLLVSRLPWHPPVPGRPTADQGRLLRRLAQAKPGIYVMIAPRGRGKSALAGMFAQTLDDACCITAPTKAAVDILR
RYAGPGAPFFAPDALLARCRAGMSARWLLVDEAAALPLPLLRQLMGYFSHVLLTTTVAGYEGTGRGFLLKFCETLPCWCP
LRLDAPLRWAANDPLERWLTETLMLEDAEVVAPAGKGAPQNTDAGAAGAGRWRIGKVGAQTWRRQPAARQAFYQLLTRAH
YRTSPIDLRRLLDAPGMSFFTAHHHRQLMAGLWLVEEGGLTSRLAHDVWAGYRRPPGSLVAQSLAAHGSAWRAPRLRSRR
ISRIAVTPTERRRGIGLELIAKAAEQAAGEGRDFLSVSFGYTAALWRFWQRAGFKLVRMGTHREASSGLYSAMALLPLSD
AGRKLTLRAANGFERDCRLAAGEQQDLRMEDWRCLAGFAFAQRPPEACRSALTRLINRSTLPLPALRLWLTQPMPDATLV
ARLALSGKKALWRHWRQETAAAMAAADARLTHRWQRICQQQAR

Sequences:

>Translated_683_residues
MTSLPPPWLACLRAETAAMKRAGVRRLLVISGASDWCAQQAAALGDALDGDWLWVGEQSECGTGSRPAALKILLGREFLH
AVFDARQSLAVDTLAALAGTLVAGSWLVLLVPPWSRWPRLPDGDSLRWSEQLQPIATPHFTRYFRAALSADPAVALLRQD
RAPQITLLVSRLPWHPPVPGRPTADQGRLLRRLAQAKPGIYVMIAPRGRGKSALAGMFAQTLDDACCITAPTKAAVDILR
RYAGPGAPFFAPDALLARCRAGMSARWLLVDEAAALPLPLLRQLMGYFSHVLLTTTVAGYEGTGRGFLLKFCETLPCWCP
LRLDAPLRWAANDPLERWLTETLMLEDAEVVAPAGKGAPQNTDAGAAGAGRWRIGKVGAQTWRRQPAARQAFYQLLTRAH
YRTSPIDLRRLLDAPGMSFFTAHHHRQLMAGLWLVEEGGLTSRLAHDVWAGYRRPPGSLVAQSLAAHGSAWRAPRLRSRR
ISRIAVTPTERRRGIGLELIAKAAEQAAGEGRDFLSVSFGYTAALWRFWQRAGFKLVRMGTHREASSGLYSAMALLPLSD
AGRKLTLRAANGFERDCRLAAGEQQDLRMEDWRCLAGFAFAQRPPEACRSALTRLINRSTLPLPALRLWLTQPMPDATLV
ARLALSGKKALWRHWRQETAAAMAAADARLTHRWQRICQQQAR
>Mature_682_residues
TSLPPPWLACLRAETAAMKRAGVRRLLVISGASDWCAQQAAALGDALDGDWLWVGEQSECGTGSRPAALKILLGREFLHA
VFDARQSLAVDTLAALAGTLVAGSWLVLLVPPWSRWPRLPDGDSLRWSEQLQPIATPHFTRYFRAALSADPAVALLRQDR
APQITLLVSRLPWHPPVPGRPTADQGRLLRRLAQAKPGIYVMIAPRGRGKSALAGMFAQTLDDACCITAPTKAAVDILRR
YAGPGAPFFAPDALLARCRAGMSARWLLVDEAAALPLPLLRQLMGYFSHVLLTTTVAGYEGTGRGFLLKFCETLPCWCPL
RLDAPLRWAANDPLERWLTETLMLEDAEVVAPAGKGAPQNTDAGAAGAGRWRIGKVGAQTWRRQPAARQAFYQLLTRAHY
RTSPIDLRRLLDAPGMSFFTAHHHRQLMAGLWLVEEGGLTSRLAHDVWAGYRRPPGSLVAQSLAAHGSAWRAPRLRSRRI
SRIAVTPTERRRGIGLELIAKAAEQAAGEGRDFLSVSFGYTAALWRFWQRAGFKLVRMGTHREASSGLYSAMALLPLSDA
GRKLTLRAANGFERDCRLAAGEQQDLRMEDWRCLAGFAFAQRPPEACRSALTRLINRSTLPLPALRLWLTQPMPDATLVA
RLALSGKKALWRHWRQETAAAMAAADARLTHRWQRICQQQAR

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=685, Percent_Identity=48.1751824817518, Blast_Score=565, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI17507621, Length=382, Percent_Identity=23.5602094240838, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640662, Length=359, Percent_Identity=25.6267409470752, Blast_Score=104, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 75205; Mature: 75074

Theoretical pI: Translated: 11.13; Mature: 11.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLPPPWLACLRAETAAMKRAGVRRLLVISGASDWCAQQAAALGDALDGDWLWVGEQSE
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCC
CGTGSRPAALKILLGREFLHAVFDARQSLAVDTLAALAGTLVAGSWLVLLVPPWSRWPRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCC
PDGDSLRWSEQLQPIATPHFTRYFRAALSADPAVALLRQDRAPQITLLVSRLPWHPPVPG
CCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCC
RPTADQGRLLRRLAQAKPGIYVMIAPRGRGKSALAGMFAQTLDDACCITAPTKAAVDILR
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHH
RYAGPGAPFFAPDALLARCRAGMSARWLLVDEAAALPLPLLRQLMGYFSHVLLTTTVAGY
HHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EGTGRGFLLKFCETLPCWCPLRLDAPLRWAANDPLERWLTETLMLEDAEVVAPAGKGAPQ
CCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCC
NTDAGAAGAGRWRIGKVGAQTWRRQPAARQAFYQLLTRAHYRTSPIDLRRLLDAPGMSFF
CCCCCCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
TAHHHRQLMAGLWLVEEGGLTSRLAHDVWAGYRRPPGSLVAQSLAAHGSAWRAPRLRSRR
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHC
ISRIAVTPTERRRGIGLELIAKAAEQAAGEGRDFLSVSFGYTAALWRFWQRAGFKLVRMG
CCEEEECCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCEEEEEC
THREASSGLYSAMALLPLSDAGRKLTLRAANGFERDCRLAAGEQQDLRMEDWRCLAGFAF
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
AQRPPEACRSALTRLINRSTLPLPALRLWLTQPMPDATLVARLALSGKKALWRHWRQETA
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHH
AAMAAADARLTHRWQRICQQQAR
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLPPPWLACLRAETAAMKRAGVRRLLVISGASDWCAQQAAALGDALDGDWLWVGEQSE
CCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCC
CGTGSRPAALKILLGREFLHAVFDARQSLAVDTLAALAGTLVAGSWLVLLVPPWSRWPRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCC
PDGDSLRWSEQLQPIATPHFTRYFRAALSADPAVALLRQDRAPQITLLVSRLPWHPPVPG
CCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCC
RPTADQGRLLRRLAQAKPGIYVMIAPRGRGKSALAGMFAQTLDDACCITAPTKAAVDILR
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHH
RYAGPGAPFFAPDALLARCRAGMSARWLLVDEAAALPLPLLRQLMGYFSHVLLTTTVAGY
HHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EGTGRGFLLKFCETLPCWCPLRLDAPLRWAANDPLERWLTETLMLEDAEVVAPAGKGAPQ
CCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCC
NTDAGAAGAGRWRIGKVGAQTWRRQPAARQAFYQLLTRAHYRTSPIDLRRLLDAPGMSFF
CCCCCCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
TAHHHRQLMAGLWLVEEGGLTSRLAHDVWAGYRRPPGSLVAQSLAAHGSAWRAPRLRSRR
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHC
ISRIAVTPTERRRGIGLELIAKAAEQAAGEGRDFLSVSFGYTAALWRFWQRAGFKLVRMG
CCEEEECCHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCEEEEEC
THREASSGLYSAMALLPLSDAGRKLTLRAANGFERDCRLAAGEQQDLRMEDWRCLAGFAF
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
AQRPPEACRSALTRLINRSTLPLPALRLWLTQPMPDATLVARLALSGKKALWRHWRQETA
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHH
AAMAAADARLTHRWQRICQQQAR
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA