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The map label for this gene is mppA [H]

Identifier: 85059475

GI number: 85059475

Start: 2509606

End: 2511225

Strand: Reverse

Name: mppA [H]

Synonym: SG1497

Alternate gene names: 85059475

Gene position: 2511225-2509606 (Counterclockwise)

Preceding gene: 85059477

Following gene: 85059474

Centisome position: 60.2

GC content: 54.88

Gene sequence:

>1620_bases
ATGCCGCGTTTTCCGTTTGCAGTTTGCGCCTTCCTGCTCGCCGCTGTTAGCGGCACCCCGCACGCCGCCACGATACCCCC
CGGTACTGTGCTGGCGGAAGTACAACATGTTGTACGCCATATTAAAGACGAGCCTTCCTCACTGGATCCGATTAAAGCCG
TCGGTTTGGTTGAGGCGCAGGTTGATCGCGATCTGTTTGAAGGGCTGGTCAATCAGGACGCCACGGGTAAGACAATTCCC
GGTGTGGCGCTGAGCTGGCAGACCAGCGACAACCAGAGTTTTGTGTTTCACCTGCGGCGTGACGCGCGTTGGTCGAATGG
GCAGCCGGTAACGGCGCAGGATTTTGTTTACAGCTGGCGCCGGCTCGTTGACCCCGCCAATCATTCCACCTTTTCCTGGT
TTGCCGAGCTCACGGGTCTGAAAAATGCCGCTGATATTATCGCCAGCAAGGTGCCCGCTGAGCAATTGGGCGTTAGCGCG
CCGGACGATTACACGCTGAAAGTGGCGCTGGATAAACCGGTGCCGTATTTCGTCAGCTTGACCGCTAATTTCAGCCTGTT
CCCGGTGAACCGCGCCACGGTGGAACGCTTCGGTCAGGAATGGACACGCGTCGGTAATCTGGTTGGCAACGGCGCGTTTG
TTCTCAGTCAGCGGGTGGTTAATGAGAAACTGGTCCTTACCCCAAATCCTCATTATTGGGATCATAAGCATACAGTGCTG
ACGCAGGTCACCTTCGTGCCGATAAGCGCCGAATCTGCCGCGCTTAACCGCTATATGGCCAACGATATAGACATTACCGA
ATCGTTTCCCAAAGACCGTTACCGGCAGTTATTGCAACAGATCCCCGATCAGGTATACACGCCGGACCAGCTGGGGACCT
ATTATTATGCCTTCAATATCCGGCGGGGGCCCACTCAAGACGTACGGGTGCGCAAAGCGCTGTCCTACGCTATTGACCGG
CGGATCATCGCCGGCAAAGTGGTCGGCTCTGGCGAAAAACCGGCCTGGCATTTTACCCCTGACGTAACGGTCGGCTTCAC
GCCCGCGGCTAGTTATTTGCAGCAGCATAGCCAGCAAGAGCTGGATGCCCAGGCGCGGGCCCTGATGCAGGCCGCCGGTT
ACGGACCGAATAAACCGTTGACCCTTACCCTGCTGTACAACACGTCGGAAAGTAATCAGAAGATCGCTATTGCCGTGGCG
TCGATGTGGAAAAAAACTCTGGGCGTCAATGTCAAATTGGTCAATCAGGAATGGAAAACCTATATCGATAGCCGCAATAC
CGGTAATTTTGACGTGGTGCGAGCATCGTGGATCGGCGATTACAACGAGCCTTCCACCTTTTTATCGCTGCTGATCTCAA
CCCATAGCGGTAACATCGCCAAGTTTAGTGATCCCGCCTACGATAAGCTGTTACAGAAGGCCAGTCGGGAAACGCAGCCG
CAGCGGCTGAGTGAAGATTACAATAAAGCAGAGACCATGATTGCCGAGCAGGCCCCAATTGCGCCGATTTATCAGTTCAC
CAATGGCCGCCTGATTAAGCCTTGGCTGAAAGGGTATCCGATCATCACCAACCCGGAAGACTTGTCCTACAGTCAGACGC
TCTATGTGGTGAAACATTGA

Upstream 100 bases:

>100_bases
TTTACCGAAAAATGTCCCGCAGTGTTAGTTTCCGCAGGGTATTTTGCCCGAACGCCGATGGGGTTAGCCCGGAATCGGCC
ATAGCGCTAAGGAACACTTT

Downstream 100 bases:

>100_bases
CGGTCAGGCGAGCAGGCCGTGTCGTTGGCGCGGGGCGCGGCGTTTAATCTGTCACCCTGCCGTGAGCCGTTGGCAGCGGC
ACTGCACATCCGGGGCGCCG

Product: putative periplasmic murein peptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MPRFPFAVCAFLLAAVSGTPHAATIPPGTVLAEVQHVVRHIKDEPSSLDPIKAVGLVEAQVDRDLFEGLVNQDATGKTIP
GVALSWQTSDNQSFVFHLRRDARWSNGQPVTAQDFVYSWRRLVDPANHSTFSWFAELTGLKNAADIIASKVPAEQLGVSA
PDDYTLKVALDKPVPYFVSLTANFSLFPVNRATVERFGQEWTRVGNLVGNGAFVLSQRVVNEKLVLTPNPHYWDHKHTVL
TQVTFVPISAESAALNRYMANDIDITESFPKDRYRQLLQQIPDQVYTPDQLGTYYYAFNIRRGPTQDVRVRKALSYAIDR
RIIAGKVVGSGEKPAWHFTPDVTVGFTPAASYLQQHSQQELDAQARALMQAAGYGPNKPLTLTLLYNTSESNQKIAIAVA
SMWKKTLGVNVKLVNQEWKTYIDSRNTGNFDVVRASWIGDYNEPSTFLSLLISTHSGNIAKFSDPAYDKLLQKASRETQP
QRLSEDYNKAETMIAEQAPIAPIYQFTNGRLIKPWLKGYPIITNPEDLSYSQTLYVVKH

Sequences:

>Translated_539_residues
MPRFPFAVCAFLLAAVSGTPHAATIPPGTVLAEVQHVVRHIKDEPSSLDPIKAVGLVEAQVDRDLFEGLVNQDATGKTIP
GVALSWQTSDNQSFVFHLRRDARWSNGQPVTAQDFVYSWRRLVDPANHSTFSWFAELTGLKNAADIIASKVPAEQLGVSA
PDDYTLKVALDKPVPYFVSLTANFSLFPVNRATVERFGQEWTRVGNLVGNGAFVLSQRVVNEKLVLTPNPHYWDHKHTVL
TQVTFVPISAESAALNRYMANDIDITESFPKDRYRQLLQQIPDQVYTPDQLGTYYYAFNIRRGPTQDVRVRKALSYAIDR
RIIAGKVVGSGEKPAWHFTPDVTVGFTPAASYLQQHSQQELDAQARALMQAAGYGPNKPLTLTLLYNTSESNQKIAIAVA
SMWKKTLGVNVKLVNQEWKTYIDSRNTGNFDVVRASWIGDYNEPSTFLSLLISTHSGNIAKFSDPAYDKLLQKASRETQP
QRLSEDYNKAETMIAEQAPIAPIYQFTNGRLIKPWLKGYPIITNPEDLSYSQTLYVVKH
>Mature_538_residues
PRFPFAVCAFLLAAVSGTPHAATIPPGTVLAEVQHVVRHIKDEPSSLDPIKAVGLVEAQVDRDLFEGLVNQDATGKTIPG
VALSWQTSDNQSFVFHLRRDARWSNGQPVTAQDFVYSWRRLVDPANHSTFSWFAELTGLKNAADIIASKVPAEQLGVSAP
DDYTLKVALDKPVPYFVSLTANFSLFPVNRATVERFGQEWTRVGNLVGNGAFVLSQRVVNEKLVLTPNPHYWDHKHTVLT
QVTFVPISAESAALNRYMANDIDITESFPKDRYRQLLQQIPDQVYTPDQLGTYYYAFNIRRGPTQDVRVRKALSYAIDRR
IIAGKVVGSGEKPAWHFTPDVTVGFTPAASYLQQHSQQELDAQARALMQAAGYGPNKPLTLTLLYNTSESNQKIAIAVAS
MWKKTLGVNVKLVNQEWKTYIDSRNTGNFDVVRASWIGDYNEPSTFLSLLISTHSGNIAKFSDPAYDKLLQKASRETQPQ
RLSEDYNKAETMIAEQAPIAPIYQFTNGRLIKPWLKGYPIITNPEDLSYSQTLYVVKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=532, Percent_Identity=67.2932330827068, Blast_Score=754, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=535, Percent_Identity=44.8598130841121, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1789397, Length=531, Percent_Identity=39.924670433145, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787762, Length=501, Percent_Identity=25.748502994012, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1789966, Length=474, Percent_Identity=24.2616033755274, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=23.7903225806452, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787551, Length=531, Percent_Identity=23.5404896421846, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787052, Length=480, Percent_Identity=20.4166666666667, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60247; Mature: 60116

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFPFAVCAFLLAAVSGTPHAATIPPGTVLAEVQHVVRHIKDEPSSLDPIKAVGLVEAQ
CCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VDRDLFEGLVNQDATGKTIPGVALSWQTSDNQSFVFHLRRDARWSNGQPVTAQDFVYSWR
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
RLVDPANHSTFSWFAELTGLKNAADIIASKVPAEQLGVSAPDDYTLKVALDKPVPYFVSL
HHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCEEEEEEECCCCCEEEEE
TANFSLFPVNRATVERFGQEWTRVGNLVGNGAFVLSQRVVNEKLVLTPNPHYWDHKHTVL
ECCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCEEEECCCCCCCCCCCEEE
TQVTFVPISAESAALNRYMANDIDITESFPKDRYRQLLQQIPDQVYTPDQLGTYYYAFNI
EEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHCCCCHHHCCEEEEEEE
RRGPTQDVRVRKALSYAIDRRIIAGKVVGSGEKPAWHFTPDVTVGFTPAASYLQQHSQQE
CCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCCEEECCHHHHHHHHHHHHH
LDAQARALMQAAGYGPNKPLTLTLLYNTSESNQKIAIAVASMWKKTLGVNVKLVNQEWKT
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHCCEEEEECHHHHH
YIDSRNTGNFDVVRASWIGDYNEPSTFLSLLISTHSGNIAKFSDPAYDKLLQKASRETQP
HHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCH
QRLSEDYNKAETMIAEQAPIAPIYQFTNGRLIKPWLKGYPIITNPEDLSYSQTLYVVKH
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECHHHCCCCEEECCCCCCCCEEEEEEEC
>Mature Secondary Structure 
PRFPFAVCAFLLAAVSGTPHAATIPPGTVLAEVQHVVRHIKDEPSSLDPIKAVGLVEAQ
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VDRDLFEGLVNQDATGKTIPGVALSWQTSDNQSFVFHLRRDARWSNGQPVTAQDFVYSWR
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
RLVDPANHSTFSWFAELTGLKNAADIIASKVPAEQLGVSAPDDYTLKVALDKPVPYFVSL
HHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCEEEEEEECCCCCEEEEE
TANFSLFPVNRATVERFGQEWTRVGNLVGNGAFVLSQRVVNEKLVLTPNPHYWDHKHTVL
ECCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCEEEECCCCCCCCCCCEEE
TQVTFVPISAESAALNRYMANDIDITESFPKDRYRQLLQQIPDQVYTPDQLGTYYYAFNI
EEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHCCCCHHHCCEEEEEEE
RRGPTQDVRVRKALSYAIDRRIIAGKVVGSGEKPAWHFTPDVTVGFTPAASYLQQHSQQE
CCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCCEEECCHHHHHHHHHHHHH
LDAQARALMQAAGYGPNKPLTLTLLYNTSESNQKIAIAVASMWKKTLGVNVKLVNQEWKT
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHCCEEEEECHHHHH
YIDSRNTGNFDVVRASWIGDYNEPSTFLSLLISTHSGNIAKFSDPAYDKLLQKASRETQP
HHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHCCCH
QRLSEDYNKAETMIAEQAPIAPIYQFTNGRLIKPWLKGYPIITNPEDLSYSQTLYVVKH
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECHHHCCCCEEECCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]