| Definition | Sodalis glossinidius str. 'morsitans', complete genome. |
|---|---|
| Accession | NC_007712 |
| Length | 4,171,146 |
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The map label for this gene is pntA
Identifier: 85059466
GI number: 85059466
Start: 2483672
End: 2485204
Strand: Reverse
Name: pntA
Synonym: SG1488
Alternate gene names: 85059466
Gene position: 2485204-2483672 (Counterclockwise)
Preceding gene: 85059468
Following gene: 85059465
Centisome position: 59.58
GC content: 56.43
Gene sequence:
>1533_bases ATGCGTATTGGTGTACCTAAAGAACGCGTTGCCAACGAAGCCCGGGTTGCCGCCACGCCTAAAACCGTCGAGCAATTGCT TAAGTTGGGTTTTAGTATTGCGATGGAAAGCGGCGCCGGCACGCTGGCGAGTTTCGAGGATGCCGCTTTTGTCGCGGCGG GCGCGACGCTGACAACTACCTCTGAAGTTTGGCAGTCGGATATCATTCTCAAAGTCAACGCGCCGACTGAGGATGAAATT GCCTTGCTGCAAAGCGGCACGACATTGATAAGTTTTATTTGGCCGGCGCAAAATGCCGACCTGCTAACGGCGCTGCGCGC TAAAAACGTGACCGTCATGGCGATGGACGCTGTGCCGCGTATCTCCCGCGCTCAGTCGCTGGACGCCCTGAGCTCGATGG CCAATATCGCCGGTTATCGCGCCATTGTTGAAGCGGCTCACGAATTCGGCCGCTTCTTTACCGGCCAGATTACGGCGGCG GGCAAAGTGCCGCCGGCCAAAGTTATGGTGATAGGCGCCGGGGTCGCGGGGCTGGCCGCCATCGGTACCGCGGGCAGCCT GGGCGCCGTGGTTCGCGCCTTCGACACCCGTCCCGAGGTGAAAGAGCAGGTGCAAAGTATGGGCGCCGAGTTCCTTGAGC TGGATTTCAAGGAGGAGGCGGGCGGTAGCGATGGTTACGCCAAGGTGATGTCGGACGCTTTTATCAAAGCCGAAATGGCG CTGTTCGCCGCACAGGCGCAAGAAGTCGATATTATCGTCACCACCGCGCTGATTCCGGGCAAACAGGCCCCCCGCTTGAT TACCAAAGAGATGGTGACCAGCATGAAGCCGGGAAGCGTTATTGTTGATCTGGCGGCGCAAACCGGCGGTAACTGTGAGC TCACCGTGGCGGACACCGTAACGGTGACCGATAATGGCGTTCGTATTATCGGCTATACCGATTTACCCAGCCGGTTACCT ACCCAATCCTCCCAACTGTACGCCACCAACCTCATCAATCTGCTGAAGTTACTTTGTAAAGAGAAACAGGGCGATATCGT GGTGGATTTCGACGACATGGTTATTCGCGGCGTCACCGTGATACGCGATGGCGAATTGACCTGGCCCGCGCCGCCTATCA CTGTTTCCGCCCAGCCGCAGCCGGCGCATGCGGCCCCTGCCGCAAAACCCGCAGAACCGCCCCGTCCGGCGTCGCCGCTG CGTAAATATGCCCTTATCGCTTTGGCGATTATTTTATTTTGCTGGCTGGCGAATGCGGCTCCGCGCGATTTTCTCTCGCA TTTTACGGTGTTCGCCCTGGCCTGTGTCGTAGGCTATTACGTTGTCTGGAATGTCAGTCATGCATTGCATACCCCGTTAA TGTCGGTCACCAATGCTATTTCCGGCATTATTGTCGTTGGCGCATTATTGCAGATAGGTGATGGCGGATGGGTTTCATTC CTGTCGTTTATCGCCGTGCTGATCGCCAGCATCAATATCTTTGGTGGTTTCACCGTCACTCAGCGCATGCTGAAAATGTT TCGTAAAAATTAA
Upstream 100 bases:
>100_bases TTGACGCCTGCTGGATTTACCGGGCGGCGGCCCGTAATGCCGCGCGTTCCGGTCCCGGCAACCTGTTATTTACAAAAGAA CTGAATAATAAGGGAAAGCT
Downstream 100 bases:
>100_bases GGGGTGAACCATGTCAGAAGGACTCGTCACGGCGGCTTATATCGCCGCCGCCATTTTATTTATTTTTAGCCTGGCGGGGC TATCCAAGCACGAAACATCG
Product: NAD(P) transhydrogenase subunit alpha
Products: NA
Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha; Pyridine nucleotide transhydrogenase subunit alpha [H]
Number of amino acids: Translated: 510; Mature: 510
Protein sequence:
>510_residues MRIGVPKERVANEARVAATPKTVEQLLKLGFSIAMESGAGTLASFEDAAFVAAGATLTTTSEVWQSDIILKVNAPTEDEI ALLQSGTTLISFIWPAQNADLLTALRAKNVTVMAMDAVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA GKVPPAKVMVIGAGVAGLAAIGTAGSLGAVVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGGSDGYAKVMSDAFIKAEMA LFAAQAQEVDIIVTTALIPGKQAPRLITKEMVTSMKPGSVIVDLAAQTGGNCELTVADTVTVTDNGVRIIGYTDLPSRLP TQSSQLYATNLINLLKLLCKEKQGDIVVDFDDMVIRGVTVIRDGELTWPAPPITVSAQPQPAHAAPAAKPAEPPRPASPL RKYALIALAIILFCWLANAAPRDFLSHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGDGGWVSF LSFIAVLIASINIFGGFTVTQRMLKMFRKN
Sequences:
>Translated_510_residues MRIGVPKERVANEARVAATPKTVEQLLKLGFSIAMESGAGTLASFEDAAFVAAGATLTTTSEVWQSDIILKVNAPTEDEI ALLQSGTTLISFIWPAQNADLLTALRAKNVTVMAMDAVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA GKVPPAKVMVIGAGVAGLAAIGTAGSLGAVVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGGSDGYAKVMSDAFIKAEMA LFAAQAQEVDIIVTTALIPGKQAPRLITKEMVTSMKPGSVIVDLAAQTGGNCELTVADTVTVTDNGVRIIGYTDLPSRLP TQSSQLYATNLINLLKLLCKEKQGDIVVDFDDMVIRGVTVIRDGELTWPAPPITVSAQPQPAHAAPAAKPAEPPRPASPL RKYALIALAIILFCWLANAAPRDFLSHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGDGGWVSF LSFIAVLIASINIFGGFTVTQRMLKMFRKN >Mature_510_residues MRIGVPKERVANEARVAATPKTVEQLLKLGFSIAMESGAGTLASFEDAAFVAAGATLTTTSEVWQSDIILKVNAPTEDEI ALLQSGTTLISFIWPAQNADLLTALRAKNVTVMAMDAVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA GKVPPAKVMVIGAGVAGLAAIGTAGSLGAVVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGGSDGYAKVMSDAFIKAEMA LFAAQAQEVDIIVTTALIPGKQAPRLITKEMVTSMKPGSVIVDLAAQTGGNCELTVADTVTVTDNGVRIIGYTDLPSRLP TQSSQLYATNLINLLKLLCKEKQGDIVVDFDDMVIRGVTVIRDGELTWPAPPITVSAQPQPAHAAPAAKPAEPPRPASPL RKYALIALAIILFCWLANAAPRDFLSHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGDGGWVSF LSFIAVLIASINIFGGFTVTQRMLKMFRKN
Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]
COG id: COG3288
COG function: function code C; NAD/NADP transhydrogenase alpha subunit
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AlaDH/PNT family [H]
Homologues:
Organism=Homo sapiens, GI122939155, Length=532, Percent_Identity=50.3759398496241, Blast_Score=478, Evalue=1e-135, Organism=Homo sapiens, GI122939153, Length=532, Percent_Identity=50.3759398496241, Blast_Score=478, Evalue=1e-135, Organism=Escherichia coli, GI1787887, Length=510, Percent_Identity=82.156862745098, Blast_Score=842, Evalue=0.0, Organism=Caenorhabditis elegans, GI17550456, Length=521, Percent_Identity=52.5911708253359, Blast_Score=498, Evalue=1e-141,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR007698 - InterPro: IPR008142 - InterPro: IPR008143 - InterPro: IPR007886 - InterPro: IPR004571 [H]
Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]
EC number: =1.6.1.2 [H]
Molecular weight: Translated: 54043; Mature: 54043
Theoretical pI: Translated: 6.08; Mature: 6.08
Prosite motif: PS00836 ALADH_PNT_1 ; PS00837 ALADH_PNT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRIGVPKERVANEARVAATPKTVEQLLKLGFSIAMESGAGTLASFEDAAFVAAGATLTTT CCCCCCHHHHCCCHHCCCCHHHHHHHHHCCHHEEECCCCCCCCCCCCCCEEECCCEEEEH SEVWQSDIILKVNAPTEDEIALLQSGTTLISFIWPAQNADLLTALRAKNVTVMAMDAVPR HHHHCCCEEEEECCCCCHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCEEEEEECCCCC ISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEECCCCCCCEEEEEECCHHHHHH IGTAGSLGAVVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGGSDGYAKVMSDAFIKAEMA HCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHEEECHHHCCCCCCHHHHHHHHHHHHHHH LFAAQAQEVDIIVTTALIPGKQAPRLITKEMVTSMKPGSVIVDLAAQTGGNCELTVADTV HHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEEE TVTDNGVRIIGYTDLPSRLPTQSSQLYATNLINLLKLLCKEKQGDIVVDFDDMVIRGVTV EEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHCEEE IRDGELTWPAPPITVSAQPQPAHAAPAAKPAEPPRPASPLRKYALIALAIILFCWLANAA EECCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC PRDFLSHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGDGGWVSF HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH LSFIAVLIASINIFGGFTVTQRMLKMFRKN HHHHHHHHHHHHHCCCHHHHHHHHHHHHCC >Mature Secondary Structure MRIGVPKERVANEARVAATPKTVEQLLKLGFSIAMESGAGTLASFEDAAFVAAGATLTTT CCCCCCHHHHCCCHHCCCCHHHHHHHHHCCHHEEECCCCCCCCCCCCCCEEECCCEEEEH SEVWQSDIILKVNAPTEDEIALLQSGTTLISFIWPAQNADLLTALRAKNVTVMAMDAVPR HHHHCCCEEEEECCCCCHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCEEEEEECCCCC ISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEECCCCCCCEEEEEECCHHHHHH IGTAGSLGAVVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGGSDGYAKVMSDAFIKAEMA HCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHEEECHHHCCCCCCHHHHHHHHHHHHHHH LFAAQAQEVDIIVTTALIPGKQAPRLITKEMVTSMKPGSVIVDLAAQTGGNCELTVADTV HHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEEE TVTDNGVRIIGYTDLPSRLPTQSSQLYATNLINLLKLLCKEKQGDIVVDFDDMVIRGVTV EEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHCEEE IRDGELTWPAPPITVSAQPQPAHAAPAAKPAEPPRPASPLRKYALIALAIILFCWLANAA EECCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC PRDFLSHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGDGGWVSF HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH LSFIAVLIASINIFGGFTVTQRMLKMFRKN HHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3525165; 1633824; 9097039; 9278503; 1932078 [H]