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The map label for this gene is aroH [H]

Identifier: 85059405

GI number: 85059405

Start: 2385807

End: 2386853

Strand: Reverse

Name: aroH [H]

Synonym: SG1427

Alternate gene names: 85059405

Gene position: 2386853-2385807 (Counterclockwise)

Preceding gene: 85059406

Following gene: 85059404

Centisome position: 57.22

GC content: 58.45

Gene sequence:

>1047_bases
ATGCAAAAGACAGATGAATTGCGCACACGGCGCATCGACCGATTAGTTGCTCCCGCCTCGCTGGCCGCCGCCTTGCCGCT
AAGCGCGGCGATGGCCGAGAATGTATTGCGAGTGCGCCAGCGTATTGAACGTATTTTACACGGCGATGATCCCCGTTTGC
TGGTGATAATCGGCCCCTGCTCCATCCACGATACCGATGCGGCGCTGGATTATGCGCGCCGGCTTAATCCGCTGCGCGTC
AAGTACCAAGACCGACTGGAAATCGTCATGCGTACCTATTTTGAAAAGCCGCGCACCGTGGTGGGTTGGAAAGGGTTGAT
TGCCGATCCGGGGCTGGACGGCAGTTTTCGCGTGAATGACGGTTTGGAGATCGCCCGGCGGCTCTTGCTGGCGGTCAACG
AATTAGGCCTACCGACCGCAACGGAATTCCTGGATATGGTCACCGGCCAATATATTGCAGATCTGATTAGCTGGGGCGCT
ATCGGCGCGCGCACTACCGAAAGCCAGATCCATCGCGAGATGGCCTCCGCGCTGTCCTGCCCGGTCGGCTTCAAGAACGG
CACGGACGGCAATATCCAAATCGCCATCGACGCCATTCGCGCCGCCCGCGCGTCCCATCTCTTTCTGTCCCCGGACAAAC
AAGGTCAGATGACGATATATCAGACCGGCGGCAATCCGTATGGGCATATTATTATGCGCGGCGGCAAAGTGCCTAATTAT
CAGCCGCCGGCGATCGCCGATGCCAGTGCGCAGTTGGCATCTTTCGGGCTGCCGGCGCATTTGCTGGTGGATTTCAGCCA
CGGCAACAGCCAGAAGCAGTATCGCCGTCAATGGGACATCGCGCATTCTGTTGGCCAACAATTACGTGACGGCAGCCGGC
AGGTGGTGGGGGTAATGGTTGAAAGTAATCTGGTGGCGGGTAATCAGACCCTGCGCGCCGACAAGCCGTTGACCTACGGT
CAATCCATTACCGATGCCTGTCTTGGCTGGGAAGACAGCGAGCGTCTGCTAGCGCTGCTGAACGACGCAGTGGATTGCCG
CTTCTAG

Upstream 100 bases:

>100_bases
TTTGCCGGGCAAGGTTGAATTCAGCGCCGGTTGGGGTATCGTGAGCAGCATCGCTTCCCGGTAACTCCACCGCGGTGAGT
CCACCATTTTAGAGATAAGC

Downstream 100 bases:

>100_bases
TCGGCTATGCGGCCCGGCCGGGTAGGATATAGCCTGCCGGGCCGTGGCCTCATTGTTGCCGCGGCGGCGTCCGCCGTTTC
ATGTCTGGCCTCTGGTTTAC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQKTDELRTRRIDRLVAPASLAAALPLSAAMAENVLRVRQRIERILHGDDPRLLVIIGPCSIHDTDAALDYARRLNPLRV
KYQDRLEIVMRTYFEKPRTVVGWKGLIADPGLDGSFRVNDGLEIARRLLLAVNELGLPTATEFLDMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIQIAIDAIRAARASHLFLSPDKQGQMTIYQTGGNPYGHIIMRGGKVPNY
QPPAIADASAQLASFGLPAHLLVDFSHGNSQKQYRRQWDIAHSVGQQLRDGSRQVVGVMVESNLVAGNQTLRADKPLTYG
QSITDACLGWEDSERLLALLNDAVDCRF

Sequences:

>Translated_348_residues
MQKTDELRTRRIDRLVAPASLAAALPLSAAMAENVLRVRQRIERILHGDDPRLLVIIGPCSIHDTDAALDYARRLNPLRV
KYQDRLEIVMRTYFEKPRTVVGWKGLIADPGLDGSFRVNDGLEIARRLLLAVNELGLPTATEFLDMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIQIAIDAIRAARASHLFLSPDKQGQMTIYQTGGNPYGHIIMRGGKVPNY
QPPAIADASAQLASFGLPAHLLVDFSHGNSQKQYRRQWDIAHSVGQQLRDGSRQVVGVMVESNLVAGNQTLRADKPLTYG
QSITDACLGWEDSERLLALLNDAVDCRF
>Mature_348_residues
MQKTDELRTRRIDRLVAPASLAAALPLSAAMAENVLRVRQRIERILHGDDPRLLVIIGPCSIHDTDAALDYARRLNPLRV
KYQDRLEIVMRTYFEKPRTVVGWKGLIADPGLDGSFRVNDGLEIARRLLLAVNELGLPTATEFLDMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNIQIAIDAIRAARASHLFLSPDKQGQMTIYQTGGNPYGHIIMRGGKVPNY
QPPAIADASAQLASFGLPAHLLVDFSHGNSQKQYRRQWDIAHSVGQQLRDGSRQVVGVMVESNLVAGNQTLRADKPLTYG
QSITDACLGWEDSERLLALLNDAVDCRF

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=70.9770114942529, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=57.9710144927536, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1788953, Length=326, Percent_Identity=54.2944785276074, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319726, Length=346, Percent_Identity=47.3988439306358, Blast_Score=320, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6320240, Length=354, Percent_Identity=45.1977401129944, Blast_Score=312, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38318; Mature: 38318

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTDELRTRRIDRLVAPASLAAALPLSAAMAENVLRVRQRIERILHGDDPRLLVIIGPC
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDTDAALDYARRLNPLRVKYQDRLEIVMRTYFEKPRTVVGWKGLIADPGLDGSFRVND
CCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCEEECCCCEEECCCCCCCEEECC
GLEIARRLLLAVNELGLPTATEFLDMVTGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNIQIAIDAIRAARASHLFLSPDKQGQMTIYQTGGNPYGHIIMRGGKVPNY
CCCCCCCCCCEEEEEEEHHHHHHHCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCC
QPPAIADASAQLASFGLPAHLLVDFSHGNSQKQYRRQWDIAHSVGQQLRDGSRQVVGVMV
CCCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ESNLVAGNQTLRADKPLTYGQSITDACLGWEDSERLLALLNDAVDCRF
ECCEEECCCEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKTDELRTRRIDRLVAPASLAAALPLSAAMAENVLRVRQRIERILHGDDPRLLVIIGPC
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
SIHDTDAALDYARRLNPLRVKYQDRLEIVMRTYFEKPRTVVGWKGLIADPGLDGSFRVND
CCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCEEECCCCEEECCCCCCCEEECC
GLEIARRLLLAVNELGLPTATEFLDMVTGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNIQIAIDAIRAARASHLFLSPDKQGQMTIYQTGGNPYGHIIMRGGKVPNY
CCCCCCCCCCEEEEEEEHHHHHHHCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCC
QPPAIADASAQLASFGLPAHLLVDFSHGNSQKQYRRQWDIAHSVGQQLRDGSRQVVGVMV
CCCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ESNLVAGNQTLRADKPLTYGQSITDACLGWEDSERLLALLNDAVDCRF
ECCEEECCCEECCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]