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The map label for this gene is nreC [H]

Identifier: 85059257

GI number: 85059257

Start: 2150987

End: 2151622

Strand: Reverse

Name: nreC [H]

Synonym: SG1279

Alternate gene names: 85059257

Gene position: 2151622-2150987 (Counterclockwise)

Preceding gene: 85059258

Following gene: 85059252

Centisome position: 51.58

GC content: 51.89

Gene sequence:

>636_bases
ATGAATAATTATAAGATCCTGCTGGTGGACGATCATGAATTGATCATCAACGGCATTATTAACCTGCTCGAACCCTATCC
GCGTTTTAAAATCGTGGCGCACATTGATGACGGTCTGGCGGTGTACAACCAGTGCCGGATACATGAACCGGACATTTTGG
TACTGGATCTCGGCCTGCCGGGCATCAATGGTTTGGACTTGATTCCCCAACTGAGATCCCGCTGGCCACAGATGTCTATT
CTGGCCTATACCGCCCATACCGAAGAATACATGGCGGTACGCACGCTGGCCGCCGGCGCCCTCGGGTATGTATTGAAAAA
CAGTCGCCAACAGGTCTTGCTGGCGGCACTCCAAACCGTGGCGGTCAACAAAAGCTATATTGATCCGGCGCTGAACCGCG
AAATGATCCATACGGCCCTGAGCATGGAAGCCGAGAATCAGGAATTGCTGACGCCGCGCGAACGACAGATTCTCAAACTT
ATCGCCGACGGTTACACCAACCGACTCATCGCCGAACAGCTGTGTATCAGCGTCAAGACGGTGGAAACCCATCGCCTGAA
TATTATGCGTAAGCTGAACGTCCACAAAGTCACGGAACTGCTGAATTGTTCCCGCCGACTGGGTTTAACTGATTAA

Upstream 100 bases:

>100_bases
GTCCGGAGAACAGATAGCCGAATTGCGGCACGCCCTGGACAGATATCTAAGCGCCGAAAATGCATCCGCAGGGATGCGAT
AACTCAAGAGGTCACAGAAT

Downstream 100 bases:

>100_bases
CCCAGGCACCTCATGCCAGCCATGGCGGTATGACTTTTCCGCCGCCGGGGTTAGGCCCCATGTCTCGCTGTTGTCGGCTA
TAATGTGGCATTGGGCGTCA

Product: putative two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MNNYKILLVDDHELIINGIINLLEPYPRFKIVAHIDDGLAVYNQCRIHEPDILVLDLGLPGINGLDLIPQLRSRWPQMSI
LAYTAHTEEYMAVRTLAAGALGYVLKNSRQQVLLAALQTVAVNKSYIDPALNREMIHTALSMEAENQELLTPRERQILKL
IADGYTNRLIAEQLCISVKTVETHRLNIMRKLNVHKVTELLNCSRRLGLTD

Sequences:

>Translated_211_residues
MNNYKILLVDDHELIINGIINLLEPYPRFKIVAHIDDGLAVYNQCRIHEPDILVLDLGLPGINGLDLIPQLRSRWPQMSI
LAYTAHTEEYMAVRTLAAGALGYVLKNSRQQVLLAALQTVAVNKSYIDPALNREMIHTALSMEAENQELLTPRERQILKL
IADGYTNRLIAEQLCISVKTVETHRLNIMRKLNVHKVTELLNCSRRLGLTD
>Mature_211_residues
MNNYKILLVDDHELIINGIINLLEPYPRFKIVAHIDDGLAVYNQCRIHEPDILVLDLGLPGINGLDLIPQLRSRWPQMSI
LAYTAHTEEYMAVRTLAAGALGYVLKNSRQQVLLAALQTVAVNKSYIDPALNREMIHTALSMEAENQELLTPRERQILKL
IADGYTNRLIAEQLCISVKTVETHRLNIMRKLNVHKVTELLNCSRRLGLTD

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=32.2115384615385, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=31.1881188118812, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1788712, Length=200, Percent_Identity=29, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=26.3414634146341, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=27.8048780487805, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=34.0659340659341, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23941; Mature: 23941

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYKILLVDDHELIINGIINLLEPYPRFKIVAHIDDGLAVYNQCRIHEPDILVLDLGLP
CCCEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCCCCCCEEEEECCCC
GINGLDLIPQLRSRWPQMSILAYTAHTEEYMAVRTLAAGALGYVLKNSRQQVLLAALQTV
CCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AVNKSYIDPALNREMIHTALSMEAENQELLTPRERQILKLIADGYTNRLIAEQLCISVKT
HHCHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VETHRLNIMRKLNVHKVTELLNCSRRLGLTD
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNYKILLVDDHELIINGIINLLEPYPRFKIVAHIDDGLAVYNQCRIHEPDILVLDLGLP
CCCEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCCCCCCEEEEECCCC
GINGLDLIPQLRSRWPQMSILAYTAHTEEYMAVRTLAAGALGYVLKNSRQQVLLAALQTV
CCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AVNKSYIDPALNREMIHTALSMEAENQELLTPRERQILKLIADGYTNRLIAEQLCISVKT
HHCHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VETHRLNIMRKLNVHKVTELLNCSRRLGLTD
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]