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The map label for this gene is cmoA

Identifier: 85059231

GI number: 85059231

Start: 2114940

End: 2115683

Strand: Reverse

Name: cmoA

Synonym: SG1253

Alternate gene names: 85059231

Gene position: 2115683-2114940 (Counterclockwise)

Preceding gene: 85059232

Following gene: 85059230

Centisome position: 50.72

GC content: 53.49

Gene sequence:

>744_bases
ATGACCCATCGTGATGACCTTTTCTCAGCGCCTATTGCCAGTTTGGGCGACTGGACTTTCGACGAGCGCGTCGCCGAAGT
CTTTCCCGATATGATCCAGCGTTCCGTACCCGGCTATTCCAATATCATTTCGATGATCGGGATGCTGGCCGGCCGTTTTG
CCCGCCCTGGAACGCAAATATATGATCTCGGCTGCGCCCTCGGCGCCGCCACGCTCGCGATGCGCCGCACCATCAGCCAT
GGCGATTGCCGCATTATTGCGGTGGACAACTCACCGGCGATGATTGACCGCTGTCGGCGCCATATTAGTGCGTTTCACGC
AACGACACCCACGGAAATCATCGAGGACGACATTAGCACGGTGCCCATTGAAAACGCCTCGCTGGTGGTGCTGAATTTTA
CCATGCAGTTTCTTGAGCCAGCGCAGCGGCAAACCTTGCTTAATCGCATTTATGCCGGGCTGAATACGGGGGGCGCATTA
GTATTATCGGAAAAATTCAGTTTTCAGGATCAGCTTATCGGTGGGCTGTTGTTCGATATGCATCATGATTTCAAAAGGGC
CAACGGCTATAGTGAATTGGAAATCAGCCAGAAACGCAGCATGCTGGAAAATGTGATGCTCACCGACACGGTGGAAGTGC
ATAAACAACGCCTGGTCGAGGCGGGCTTTGGTCATGCCGAGCTTTGGTTCCAGTGCTTCAATTTCGGTTCATTGATCTCC
ATTAAACCGGAGAGCGGGCAGTGA

Upstream 100 bases:

>100_bases
CTTCCTTGCCTGAACCGGCCACCCGCTACCGCGCGGGACACATGCTTTATCGGCACTTTCTGATAGAATAGGCGTTTTGT
ACAACGACGCCTATTTTGCC

Downstream 100 bases:

>100_bases
GTCAGTTTGCCGATTTTTATCAGCTTATCGCCAAGAGTCCTCTCAGCCATTGGCTTAATACCCTGCCTGCGCAGCTTAGC
GAGTGGGAGCAAACCTCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTHRDDLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAGRFARPGTQIYDLGCALGAATLAMRRTISH
GDCRIIAVDNSPAMIDRCRRHISAFHATTPTEIIEDDISTVPIENASLVVLNFTMQFLEPAQRQTLLNRIYAGLNTGGAL
VLSEKFSFQDQLIGGLLFDMHHDFKRANGYSELEISQKRSMLENVMLTDTVEVHKQRLVEAGFGHAELWFQCFNFGSLIS
IKPESGQ

Sequences:

>Translated_247_residues
MTHRDDLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAGRFARPGTQIYDLGCALGAATLAMRRTISH
GDCRIIAVDNSPAMIDRCRRHISAFHATTPTEIIEDDISTVPIENASLVVLNFTMQFLEPAQRQTLLNRIYAGLNTGGAL
VLSEKFSFQDQLIGGLLFDMHHDFKRANGYSELEISQKRSMLENVMLTDTVEVHKQRLVEAGFGHAELWFQCFNFGSLIS
IKPESGQ
>Mature_246_residues
THRDDLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAGRFARPGTQIYDLGCALGAATLAMRRTISHG
DCRIIAVDNSPAMIDRCRRHISAFHATTPTEIIEDDISTVPIENASLVVLNFTMQFLEPAQRQTLLNRIYAGLNTGGALV
LSEKFSFQDQLIGGLLFDMHHDFKRANGYSELEISQKRSMLENVMLTDTVEVHKQRLVEAGFGHAELWFQCFNFGSLISI
KPESGQ

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=246, Percent_Identity=76.8292682926829, Blast_Score=412, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_SODGM (Q2NTJ7)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454933.1
- ProteinModelPortal:   Q2NTJ7
- SMR:   Q2NTJ7
- STRING:   Q2NTJ7
- GeneID:   3867860
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG1253
- NMPDR:   fig|343509.6.peg.2597
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- PhylomeDB:   Q2NTJ7
- BioCyc:   SGLO343509:SG1253-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27544; Mature: 27413

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: BINDING 39-39 BINDING 89-89 BINDING 132-132 BINDING 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRDDLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAGRFARPGTQI
CCCCHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHH
YDLGCALGAATLAMRRTISHGDCRIIAVDNSPAMIDRCRRHISAFHATTPTEIIEDDIST
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCC
VPIENASLVVLNFTMQFLEPAQRQTLLNRIYAGLNTGGALVLSEKFSFQDQLIGGLLFDM
CCCCCCCEEEEEHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHH
HHDFKRANGYSELEISQKRSMLENVMLTDTVEVHKQRLVEAGFGHAELWFQCFNFGSLIS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEE
IKPESGQ
ECCCCCC
>Mature Secondary Structure 
THRDDLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAGRFARPGTQI
CCCHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHH
YDLGCALGAATLAMRRTISHGDCRIIAVDNSPAMIDRCRRHISAFHATTPTEIIEDDIST
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCC
VPIENASLVVLNFTMQFLEPAQRQTLLNRIYAGLNTGGALVLSEKFSFQDQLIGGLLFDM
CCCCCCCEEEEEHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHH
HHDFKRANGYSELEISQKRSMLENVMLTDTVEVHKQRLVEAGFGHAELWFQCFNFGSLIS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEE
IKPESGQ
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA