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The map label for this gene is focA [H]

Identifier: 85058967

GI number: 85058967

Start: 1627161

End: 1628018

Strand: Reverse

Name: focA [H]

Synonym: SG0989

Alternate gene names: 85058967

Gene position: 1628018-1627161 (Counterclockwise)

Preceding gene: 85058977

Following gene: 85058966

Centisome position: 39.03

GC content: 51.98

Gene sequence:

>858_bases
ATGAAAGCCGACAACCCTTTTGATTTGTTATTACCTCCGGCGGCGGCAAAAGTGGCTGAGGAAGCGGGCGTCTATAAAGC
GACGAAACGCCCCAGCACCACCTTTTTCCTAGCGATAACCGCGGGCGTTTTAATCTCCATCGCGTTCGTGTTCTATATCA
CCGCTACTACCGGTACCGCTGCCGTACCTTACGGCTTCGCCAAACTTATCGGCGGTTTTTGTTTCTCTCTGGGGTTAATG
CTGGTCATCATCACCGGCGTGGATCTGTTTACCTCGTCGGTACTGATTGTCGTGGCCCGAGCGAGCGGCCGTATCAATTG
GGCACAGCTGGTGCGTAATTGGATCAATGTTTATGTCGGCAACCTGATAGGGGCACTGTTATTTGTGGCCCTTATCTGGT
TTGCGGGTCAGCATATGGTCGCCAACGGCGCCTGGGGACTGAACATGTTGCAGACTGCCGACCATAAAATGCATCACACC
TTTGTCGAGGCGGTCTGCCTCGGTATTTTGGCAAACTTGATGATTTGCCTGGCGGTCTGGACCAGTTATTCCGGTCGCAG
CATGTTCGATAAAATGTTCGCCATGATTATGCCGGTCACGATGTTTGTCGCCAGCGGGTTTGAGCATAGTATTGCCAACA
TGTTCATGATCCCGATGGTGATCGTTATCAAGAATTTCGCCTCGCCAGCGTTCTGGCAGGCCATCGGGATGACGCCGGAG
CAATTCGCCAACCTGACGGTCGCCAATTTCATCACCGACAATCTGATTCCGGTTACGATCGGCAACATTATCGGCGGTGG
TTTACTGGTAGGGTTAACGTATTGGGTAATTTATCTGCGCGGTGACAACCAGCATTAA

Upstream 100 bases:

>100_bases
TTTTTCTCTTCAAATTTGGCCACCTATGATCCATGTCAATTTTTGTCCTATACTGAGTTGGTAGAATTAATGCGTAAATT
AATTCCACGAAAGAGTTAGT

Downstream 100 bases:

>100_bases
GTTGTGCCGCCGAAGCCGGATTGTCGAAATCCACATTAGAAGGTAGGTGTATAATGACCGATCTGAATAGCAAACTGTCC
ACGGCCTGGGAAGGTTTTAA

Product: formate transporter

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: Formate channel 1 [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKADNPFDLLLPPAAAKVAEEAGVYKATKRPSTTFFLAITAGVLISIAFVFYITATTGTAAVPYGFAKLIGGFCFSLGLM
LVIITGVDLFTSSVLIVVARASGRINWAQLVRNWINVYVGNLIGALLFVALIWFAGQHMVANGAWGLNMLQTADHKMHHT
FVEAVCLGILANLMICLAVWTSYSGRSMFDKMFAMIMPVTMFVASGFEHSIANMFMIPMVIVIKNFASPAFWQAIGMTPE
QFANLTVANFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRGDNQH

Sequences:

>Translated_285_residues
MKADNPFDLLLPPAAAKVAEEAGVYKATKRPSTTFFLAITAGVLISIAFVFYITATTGTAAVPYGFAKLIGGFCFSLGLM
LVIITGVDLFTSSVLIVVARASGRINWAQLVRNWINVYVGNLIGALLFVALIWFAGQHMVANGAWGLNMLQTADHKMHHT
FVEAVCLGILANLMICLAVWTSYSGRSMFDKMFAMIMPVTMFVASGFEHSIANMFMIPMVIVIKNFASPAFWQAIGMTPE
QFANLTVANFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRGDNQH
>Mature_285_residues
MKADNPFDLLLPPAAAKVAEEAGVYKATKRPSTTFFLAITAGVLISIAFVFYITATTGTAAVPYGFAKLIGGFCFSLGLM
LVIITGVDLFTSSVLIVVARASGRINWAQLVRNWINVYVGNLIGALLFVALIWFAGQHMVANGAWGLNMLQTADHKMHHT
FVEAVCLGILANLMICLAVWTSYSGRSMFDKMFAMIMPVTMFVASGFEHSIANMFMIPMVIVIKNFASPAFWQAIGMTPE
QFANLTVANFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRGDNQH

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=285, Percent_Identity=77.1929824561403, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1788837, Length=282, Percent_Identity=47.1631205673759, Blast_Score=270, Evalue=8e-74,
Organism=Escherichia coli, GI87082249, Length=221, Percent_Identity=32.579185520362, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321779, Length=206, Percent_Identity=28.6407766990291, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 30960; Mature: 30960

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADNPFDLLLPPAAAKVAEEAGVYKATKRPSTTFFLAITAGVLISIAFVFYITATTGTA
CCCCCCCCEEECCHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVPYGFAKLIGGFCFSLGLMLVIITGVDLFTSSVLIVVARASGRINWAQLVRNWINVYVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
NLIGALLFVALIWFAGQHMVANGAWGLNMLQTADHKMHHTFVEAVCLGILANLMICLAVW
HHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSYSGRSMFDKMFAMIMPVTMFVASGFEHSIANMFMIPMVIVIKNFASPAFWQAIGMTPE
HCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
QFANLTVANFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRGDNQH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC
>Mature Secondary Structure
MKADNPFDLLLPPAAAKVAEEAGVYKATKRPSTTFFLAITAGVLISIAFVFYITATTGTA
CCCCCCCCEEECCHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVPYGFAKLIGGFCFSLGLMLVIITGVDLFTSSVLIVVARASGRINWAQLVRNWINVYVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
NLIGALLFVALIWFAGQHMVANGAWGLNMLQTADHKMHHTFVEAVCLGILANLMICLAVW
HHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSYSGRSMFDKMFAMIMPVTMFVASGFEHSIANMFMIPMVIVIKNFASPAFWQAIGMTPE
HCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
QFANLTVANFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRGDNQH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]