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The map label for this gene is galE [H]

Identifier: 85058875

GI number: 85058875

Start: 1457168

End: 1458187

Strand: Reverse

Name: galE [H]

Synonym: SG0897

Alternate gene names: 85058875

Gene position: 1458187-1457168 (Counterclockwise)

Preceding gene: 85058876

Following gene: 85058874

Centisome position: 34.96

GC content: 58.63

Gene sequence:

>1020_bases
ATGTCAGTACTGGTTACGGGTGGTAGCGGTTACATTGGCAGCCACACCTGCTTACAGATTATCGCTGCCGGCGTGACGCC
CGTCATTATCGACAACTTAGCTAACAGCAAGCGTTCAGTATTGTCTGCGATTGGCCGACTGAGCGGCCATACGCCGGCGT
TTTATCAAGGCGACATCCGCGATCAACGGCTACTGACGCAGATTTTCGCCGAGCACGATATTGACGCAGTGATCCATTTT
GCCGGTCTGAAGGCGGTAGGGGAATCGGTCACCCAGCCCATAGACTATTATGATAATAACGTTTACGGCACCCTCACGCT
GGTGAAAGCCATGCGGGAGGCCGGTATCTTTAACCTGATCTTCAGCTCCTCCGCGACCGTCTATGGCTATCAGCCTGTGA
TCCCTTATGACGAAAGTCTTCGCACCGGCCGCCCTGCCAGCCCCTACGGCCGCAGCAAATTGATGGTTGAAGAGATTTTG
CAGGATCTACAGCACGCCGATCCCCGCTGGAGCGTCAGCCTGCTGCGTTATTTCAATCCGGTCGGCGCTCATCCCTCGGG
CGAGATGGGCGAAGATCCCCAGGGCCAGCCCAACAACCTGATGCCCTTTATTGCGCAAGTCGCGGTGGGACGTCGCCCGT
CACTGGCCATTTTTGGCAACGATTTTCCGACTCCTGACGGCACCGGCGTGCGCGACTATATTCATGTATTAGATCTGGCC
GATGGTCATCTTGCGGCGCTGACCACCTTACGCGACCGGCCGCCCGGGGTGCATATTTATAATCTGGGCGCGGGCAAAGG
CCATAGCGTGCTGGACGTGGTAGCAGCGTTCAGCCAGGCCTGCGGCAAGCCACTGCCATACCATTTCGCTCCCCGCCGCG
ACGGCGATTTGGCCGCCTATTGGGCTGCGCCGGAAAAGGCCGCGCGGGAATTGCACTGGCGGGTCAGCCGGACGCTGGAA
GACATGGTCCGCGACACCTGGCACTGGCAATCCCGGCACCCGAACGGCTATCCGGATTAA

Upstream 100 bases:

>100_bases
CTATTATGAATGTAACCGATTTCATAAATAGCGGCAGGAACACTCTTTTTTTACCGTGCTCGTGCTACTATAATGAAGGA
AAAATGAAGGGAGTTGAACT

Downstream 100 bases:

>100_bases
GGAAATAGCATGCAGCCATTTAATCCCGTCGATCATCCGCATCGGCGTTACAACCCTTTGACCGGCCAATGGATCCTCGT
TTCGCCTCACAGGGCAAAGC

Product: UDP-galactose-4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSVLVTGGSGYIGSHTCLQIIAAGVTPVIIDNLANSKRSVLSAIGRLSGHTPAFYQGDIRDQRLLTQIFAEHDIDAVIHF
AGLKAVGESVTQPIDYYDNNVYGTLTLVKAMREAGIFNLIFSSSATVYGYQPVIPYDESLRTGRPASPYGRSKLMVEEIL
QDLQHADPRWSVSLLRYFNPVGAHPSGEMGEDPQGQPNNLMPFIAQVAVGRRPSLAIFGNDFPTPDGTGVRDYIHVLDLA
DGHLAALTTLRDRPPGVHIYNLGAGKGHSVLDVVAAFSQACGKPLPYHFAPRRDGDLAAYWAAPEKAARELHWRVSRTLE
DMVRDTWHWQSRHPNGYPD

Sequences:

>Translated_339_residues
MSVLVTGGSGYIGSHTCLQIIAAGVTPVIIDNLANSKRSVLSAIGRLSGHTPAFYQGDIRDQRLLTQIFAEHDIDAVIHF
AGLKAVGESVTQPIDYYDNNVYGTLTLVKAMREAGIFNLIFSSSATVYGYQPVIPYDESLRTGRPASPYGRSKLMVEEIL
QDLQHADPRWSVSLLRYFNPVGAHPSGEMGEDPQGQPNNLMPFIAQVAVGRRPSLAIFGNDFPTPDGTGVRDYIHVLDLA
DGHLAALTTLRDRPPGVHIYNLGAGKGHSVLDVVAAFSQACGKPLPYHFAPRRDGDLAAYWAAPEKAARELHWRVSRTLE
DMVRDTWHWQSRHPNGYPD
>Mature_338_residues
SVLVTGGSGYIGSHTCLQIIAAGVTPVIIDNLANSKRSVLSAIGRLSGHTPAFYQGDIRDQRLLTQIFAEHDIDAVIHFA
GLKAVGESVTQPIDYYDNNVYGTLTLVKAMREAGIFNLIFSSSATVYGYQPVIPYDESLRTGRPASPYGRSKLMVEEILQ
DLQHADPRWSVSLLRYFNPVGAHPSGEMGEDPQGQPNNLMPFIAQVAVGRRPSLAIFGNDFPTPDGTGVRDYIHVLDLAD
GHLAALTTLRDRPPGVHIYNLGAGKGHSVLDVVAAFSQACGKPLPYHFAPRRDGDLAAYWAAPEKAARELHWRVSRTLED
MVRDTWHWQSRHPNGYPD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=52.6315789473684, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=52.6315789473684, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=52.6315789473684, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI7657641, Length=279, Percent_Identity=29.3906810035842, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=72.2713864306785, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI1788353, Length=358, Percent_Identity=26.536312849162, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994969, Length=357, Percent_Identity=25.2100840336134, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=45.5072463768116, Blast_Score=324, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=45.2449567723343, Blast_Score=324, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI17568069, Length=270, Percent_Identity=25.1851851851852, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=48.3965014577259, Blast_Score=333, Evalue=2e-92,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=52.463768115942, Blast_Score=376, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37181; Mature: 37050

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVTGGSGYIGSHTCLQIIAAGVTPVIIDNLANSKRSVLSAIGRLSGHTPAFYQGDIR
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCH
DQRLLTQIFAEHDIDAVIHFAGLKAVGESVTQPIDYYDNNVYGTLTLVKAMREAGIFNLI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCEEEE
FSSSATVYGYQPVIPYDESLRTGRPASPYGRSKLMVEEILQDLQHADPRWSVSLLRYFNP
ECCCCEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGAHPSGEMGEDPQGQPNNLMPFIAQVAVGRRPSLAIFGNDFPTPDGTGVRDYIHVLDLA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCC
DGHLAALTTLRDRPPGVHIYNLGAGKGHSVLDVVAAFSQACGKPLPYHFAPRRDGDLAAY
CCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
WAAPEKAARELHWRVSRTLEDMVRDTWHWQSRHPNGYPD
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVLVTGGSGYIGSHTCLQIIAAGVTPVIIDNLANSKRSVLSAIGRLSGHTPAFYQGDIR
EEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEECCCH
DQRLLTQIFAEHDIDAVIHFAGLKAVGESVTQPIDYYDNNVYGTLTLVKAMREAGIFNLI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCEEEE
FSSSATVYGYQPVIPYDESLRTGRPASPYGRSKLMVEEILQDLQHADPRWSVSLLRYFNP
ECCCCEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGAHPSGEMGEDPQGQPNNLMPFIAQVAVGRRPSLAIFGNDFPTPDGTGVRDYIHVLDLA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCC
DGHLAALTTLRDRPPGVHIYNLGAGKGHSVLDVVAAFSQACGKPLPYHFAPRRDGDLAAY
CCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEE
WAAPEKAARELHWRVSRTLEDMVRDTWHWQSRHPNGYPD
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]