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The map label for this gene is nagC [H]

Identifier: 85058792

GI number: 85058792

Start: 1374682

End: 1375935

Strand: Reverse

Name: nagC [H]

Synonym: SG0814

Alternate gene names: 85058792

Gene position: 1375935-1374682 (Counterclockwise)

Preceding gene: 85058793

Following gene: 85058791

Centisome position: 32.99

GC content: 58.05

Gene sequence:

>1254_bases
ATGACACCAGGCGGACAGACCCCGATAGGCAATATTGACCTTGTTAAACAGTTAAATAACGCGGCGGTCTACCGTCTCAT
CGATCAAATGGGCCCCATTTCCCGTATTCAGATAGCAGAACAAAGTCAGCTCGCGCCCGCCAGTATTACCAAGATCACCC
GCCAACTGCTGGAACGCGGCCTGATCCGTGAAGTGGATCAGCAAGCCTCCACCGGCGGCCGGCGGGCTATCTCCATCGTG
GCCGAAACCCGTGGCTTCCAGGCCATCGGCGTTCGCCTCGGCCGGCATGATGCGACGATCATGCTTTATGATTTGAGCGG
CAAGGCCCTGCAGGAAGCCTACTTCCCGCTGCCGCAGCGGACCCAGCAGACGCTGGAGCTGGCGCTGATGGAAGCTATCG
CCGACTTTCTTGAGCAGGCGCAGCGTAAAATCCGCGATCTCATCGCTATTTCGGTAATTTTACCGGGGCTGGTCGACCCC
TTCTCCGGCATTGTCCGCTATATGCCTCATATACAGGTACACCACTGGCCGCTGGTAGATCAGTTGCAGCAGCGTTTCCA
TCTCACCGCGTTTGTAGGCCACGACATTCGCAGTCTCGCGCTGGCGGAGCACTATTTCGGTGCAACCCAGGATTGCGCCG
ATTCCATATTGGTTCGTTTGCACCGCGGTACCGGGGCAGGCATCTTGATAAATGGCCAGATTTTCCTTGGCAGTAACGGT
AACGTGGGCGAGATTGGCCATATTCAGGTCGATCCGCTGGGAGAACGCTGCCACTGCGGCAATTTTGGCTGTCTGGAAAC
CATTGCCGCCAATGCCGCGATCGAGCAACGGGTGCGCCTGCTGCTCAGTCAGGGTTATGCCAGTAAACTGACGCCGGACG
ACTGCCGGATAGACACCATCTGTCTGGCAGCCAACCGCGGTGACGGGTTGGCGGTGGAAGTGATCGAGCACGTCGGCCGT
CAGTTGGGTAAGGTGATAGCGCTCAGCATTAACCTGTTCAATCCGCAAAAGGTGGTATTGGCGGGCGAAATCACCGAGGC
CCACAAAATTTTGCTGCCGGCCGTGCAGCGCTGCATCGATAATCAGGTGCTGAAAGCCTTCCGGCAAAACTTGCCGGTGG
TCATCTCAGTGCTGGATCATGGTTCGGCCATCGGCGCTTTCGCCCTGGTGAAGCGCGCCATGCTTAACGGCGTGCTGCTT
CAGCGGTTGCTTGAAGCCGACGCAACGCCGCATCGGCGCATCGGCGCAGGGTAA

Upstream 100 bases:

>100_bases
CGGTCGGCAAAATCGCCAACTTAACCGCCTTCACCCACGATTATAAAATCAGTAAAACTATCGTTAACGGCGACGAAGTT
TGACCATAAGCGAGTAAGCG

Downstream 100 bases:

>100_bases
AGACTGCCTCCTAACGCATCAAAGTTCTTCGGGGGCGCCGATTTAACCGGTCCTGCCCGACAAATGGCCTGCGTCACGTT
ACACGACAACGTTGCAAGCC

Product: N-acetylglucosamine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTPGGQTPIGNIDLVKQLNNAAVYRLIDQMGPISRIQIAEQSQLAPASITKITRQLLERGLIREVDQQASTGGRRAISIV
AETRGFQAIGVRLGRHDATIMLYDLSGKALQEAYFPLPQRTQQTLELALMEAIADFLEQAQRKIRDLIAISVILPGLVDP
FSGIVRYMPHIQVHHWPLVDQLQQRFHLTAFVGHDIRSLALAEHYFGATQDCADSILVRLHRGTGAGILINGQIFLGSNG
NVGEIGHIQVDPLGERCHCGNFGCLETIAANAAIEQRVRLLLSQGYASKLTPDDCRIDTICLAANRGDGLAVEVIEHVGR
QLGKVIALSINLFNPQKVVLAGEITEAHKILLPAVQRCIDNQVLKAFRQNLPVVISVLDHGSAIGAFALVKRAMLNGVLL
QRLLEADATPHRRIGAG

Sequences:

>Translated_417_residues
MTPGGQTPIGNIDLVKQLNNAAVYRLIDQMGPISRIQIAEQSQLAPASITKITRQLLERGLIREVDQQASTGGRRAISIV
AETRGFQAIGVRLGRHDATIMLYDLSGKALQEAYFPLPQRTQQTLELALMEAIADFLEQAQRKIRDLIAISVILPGLVDP
FSGIVRYMPHIQVHHWPLVDQLQQRFHLTAFVGHDIRSLALAEHYFGATQDCADSILVRLHRGTGAGILINGQIFLGSNG
NVGEIGHIQVDPLGERCHCGNFGCLETIAANAAIEQRVRLLLSQGYASKLTPDDCRIDTICLAANRGDGLAVEVIEHVGR
QLGKVIALSINLFNPQKVVLAGEITEAHKILLPAVQRCIDNQVLKAFRQNLPVVISVLDHGSAIGAFALVKRAMLNGVLL
QRLLEADATPHRRIGAG
>Mature_416_residues
TPGGQTPIGNIDLVKQLNNAAVYRLIDQMGPISRIQIAEQSQLAPASITKITRQLLERGLIREVDQQASTGGRRAISIVA
ETRGFQAIGVRLGRHDATIMLYDLSGKALQEAYFPLPQRTQQTLELALMEAIADFLEQAQRKIRDLIAISVILPGLVDPF
SGIVRYMPHIQVHHWPLVDQLQQRFHLTAFVGHDIRSLALAEHYFGATQDCADSILVRLHRGTGAGILINGQIFLGSNGN
VGEIGHIQVDPLGERCHCGNFGCLETIAANAAIEQRVRLLLSQGYASKLTPDDCRIDTICLAANRGDGLAVEVIEHVGRQ
LGKVIALSINLFNPQKVVLAGEITEAHKILLPAVQRCIDNQVLKAFRQNLPVVISVLDHGSAIGAFALVKRAMLNGVLLQ
RLLEADATPHRRIGAG

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=268, Percent_Identity=25.3731343283582, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI298566325, Length=268, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4885285, Length=268, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI190014632, Length=268, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=405, Percent_Identity=78.2716049382716, Blast_Score=653, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=398, Percent_Identity=39.4472361809045, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI87082127, Length=342, Percent_Identity=23.0994152046784, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=25, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790522, Length=290, Percent_Identity=23.448275862069, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45448; Mature: 45317

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGGQTPIGNIDLVKQLNNAAVYRLIDQMGPISRIQIAEQSQLAPASITKITRQLLERG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECHHCCCCHHHHHHHHHHHHHHH
LIREVDQQASTGGRRAISIVAETRGFQAIGVRLGRHDATIMLYDLSGKALQEAYFPLPQR
HHHHHHHHHCCCCCCEEEEEECCCCCEEEHEEECCCCCEEEEEECCCHHHHHHHCCCCHH
TQQTLELALMEAIADFLEQAQRKIRDLIAISVILPGLVDPFSGIVRYMPHIQVHHWPLVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCHHH
QLQQRFHLTAFVGHDIRSLALAEHYFGATQDCADSILVRLHRGTGAGILINGQIFLGSNG
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCC
NVGEIGHIQVDPLGERCHCGNFGCLETIAANAAIEQRVRLLLSQGYASKLTPDDCRIDTI
CCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
CLAANRGDGLAVEVIEHVGRQLGKVIALSINLFNPQKVVLAGEITEAHKILLPAVQRCID
EEEECCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHH
NQVLKAFRQNLPVVISVLDHGSAIGAFALVKRAMLNGVLLQRLLEADATPHRRIGAG
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TPGGQTPIGNIDLVKQLNNAAVYRLIDQMGPISRIQIAEQSQLAPASITKITRQLLERG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECHHCCCCHHHHHHHHHHHHHHH
LIREVDQQASTGGRRAISIVAETRGFQAIGVRLGRHDATIMLYDLSGKALQEAYFPLPQR
HHHHHHHHHCCCCCCEEEEEECCCCCEEEHEEECCCCCEEEEEECCCHHHHHHHCCCCHH
TQQTLELALMEAIADFLEQAQRKIRDLIAISVILPGLVDPFSGIVRYMPHIQVHHWPLVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCHHH
QLQQRFHLTAFVGHDIRSLALAEHYFGATQDCADSILVRLHRGTGAGILINGQIFLGSNG
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCC
NVGEIGHIQVDPLGERCHCGNFGCLETIAANAAIEQRVRLLLSQGYASKLTPDDCRIDTI
CCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
CLAANRGDGLAVEVIEHVGRQLGKVIALSINLFNPQKVVLAGEITEAHKILLPAVQRCID
EEEECCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHH
NQVLKAFRQNLPVVISVLDHGSAIGAFALVKRAMLNGVLLQRLLEADATPHRRIGAG
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]