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The map label for this gene is lpxH

Identifier: 85058681

GI number: 85058681

Start: 1184778

End: 1185497

Strand: Reverse

Name: lpxH

Synonym: SG0703

Alternate gene names: 85058681

Gene position: 1185497-1184778 (Counterclockwise)

Preceding gene: 85058682

Following gene: 85058680

Centisome position: 28.42

GC content: 59.31

Gene sequence:

>720_bases
ATGTCAACCCTGTTCGTCGCAGATATTCATCTTTGCGCACAAGAGCCGGCGATCACCGCCGGTTTTCTGCATTTTTTACG
CACGCGCGCGATCGCCGCGCAAGCGCTATACATCCTTGGCGATTTGTTTGAGGTGTGGATAGGCGATGACGATCCCAATC
CGCTGCATCACGAGATTGCCGTCGCGCTACAGGCGCTGACCCAGCGTGGCATTCCCTGCTATTTTATCCACGGGAATCGT
GATTTCCTGCTCGGCAAGCGTTATGCCGCCGCCTGCGGCATAACGCTGTTGCCCGCGCAGCGGGTGATGCAGCTGGACGA
GTTACGGGTCGTGATTTTGCATGGCGACACGCTGTGCACCGACGATAACGACTATCAGCGTTTTCGCCGCCGGGTGCATC
AACGTTGGCTACAGCGGCTATTTTTGTCCCTGCCGCTGCAGCTACGGCTGCGTATTGCCGACAGGATGCGTGCCAATAGC
CTGCGCGCCAACGCCGGTAAAACCGCCGACATTATGGACATCAATGCGCAGGCGGTTATGGCCGTGATGGATGATACCGG
CGCAACGGTGATGATCCATGGCCATACCCACCGGCCGGCGATCCATCAACTGCCCGGGGAGCGCCGTCGTGCGGTACTGG
GCGCCTGGCACCATCAGGGATCGGCCATCGAGGTTTCCACCAGCGGCGTCATGCTGCATGAGTTTTCTTTCGGCGGCTGA

Upstream 100 bases:

>100_bases
ATCAAAGGCGTCGACACCGGCCGCAGCGGCATGCATCAGGACGTCCCGAAAGAAGACGTTGTCATCACCCATGTGACCGT
TGCGAAGTAATTCCGCCCGC

Downstream 100 bases:

>100_bases
AATCCGCTGTCGGTGGACCCGTCGGCGTTCTCCTGCCTCCTGAAACGATACGCTTATGTCTGTGGTCCTGCGTACCTTCG
GCACCGCCGCTCTTACAACA

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSTLFVADIHLCAQEPAITAGFLHFLRTRAIAAQALYILGDLFEVWIGDDDPNPLHHEIAVALQALTQRGIPCYFIHGNR
DFLLGKRYAAACGITLLPAQRVMQLDELRVVILHGDTLCTDDNDYQRFRRRVHQRWLQRLFLSLPLQLRLRIADRMRANS
LRANAGKTADIMDINAQAVMAVMDDTGATVMIHGHTHRPAIHQLPGERRRAVLGAWHHQGSAIEVSTSGVMLHEFSFGG

Sequences:

>Translated_239_residues
MSTLFVADIHLCAQEPAITAGFLHFLRTRAIAAQALYILGDLFEVWIGDDDPNPLHHEIAVALQALTQRGIPCYFIHGNR
DFLLGKRYAAACGITLLPAQRVMQLDELRVVILHGDTLCTDDNDYQRFRRRVHQRWLQRLFLSLPLQLRLRIADRMRANS
LRANAGKTADIMDINAQAVMAVMDDTGATVMIHGHTHRPAIHQLPGERRRAVLGAWHHQGSAIEVSTSGVMLHEFSFGG
>Mature_238_residues
STLFVADIHLCAQEPAITAGFLHFLRTRAIAAQALYILGDLFEVWIGDDDPNPLHHEIAVALQALTQRGIPCYFIHGNRD
FLLGKRYAAACGITLLPAQRVMQLDELRVVILHGDTLCTDDNDYQRFRRRVHQRWLQRLFLSLPLQLRLRIADRMRANSL
RANAGKTADIMDINAQAVMAVMDDTGATVMIHGHTHRPAIHQLPGERRRAVLGAWHHQGSAIEVSTSGVMLHEFSFGG

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family

Homologues:

Organism=Escherichia coli, GI1786735, Length=240, Percent_Identity=59.5833333333333, Blast_Score=302, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXH_SODGM (Q2NV47)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454383.1
- ProteinModelPortal:   Q2NV47
- STRING:   Q2NV47
- GeneID:   3868620
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0703
- NMPDR:   fig|343509.6.peg.1519
- eggNOG:   COG2908
- HOGENOM:   HBG288883
- OMA:   CHGDTLC
- PhylomeDB:   Q2NV47
- ProtClustDB:   PRK05340
- BioCyc:   SGLO343509:SG0703-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00575
- InterPro:   IPR004843
- InterPro:   IPR010138
- TIGRFAMs:   TIGR01854

Pfam domain/function: PF00149 Metallophos

EC number: 3.6.1.-

Molecular weight: Translated: 26812; Mature: 26681

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLFVADIHLCAQEPAITAGFLHFLRTRAIAAQALYILGDLFEVWIGDDDPNPLHHEIA
CCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHH
VALQALTQRGIPCYFIHGNRDFLLGKRYAAACGITLLPAQRVMQLDELRVVILHGDTLCT
HHHHHHHHCCCEEEEEECCCEEEECCHHHHHCCEEEECHHHHHHHHHEEEEEEECCEEEC
DDNDYQRFRRRVHQRWLQRLFLSLPLQLRLRIADRMRANSLRANAGKTADIMDINAQAVM
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHEEE
AVMDDTGATVMIHGHTHRPAIHQLPGERRRAVLGAWHHQGSAIEVSTSGVMLHEFSFGG
EEECCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCC
>Mature Secondary Structure 
STLFVADIHLCAQEPAITAGFLHFLRTRAIAAQALYILGDLFEVWIGDDDPNPLHHEIA
CEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHH
VALQALTQRGIPCYFIHGNRDFLLGKRYAAACGITLLPAQRVMQLDELRVVILHGDTLCT
HHHHHHHHCCCEEEEEECCCEEEECCHHHHHCCEEEECHHHHHHHHHEEEEEEECCEEEC
DDNDYQRFRRRVHQRWLQRLFLSLPLQLRLRIADRMRANSLRANAGKTADIMDINAQAVM
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHEEE
AVMDDTGATVMIHGHTHRPAIHQLPGERRRAVLGAWHHQGSAIEVSTSGVMLHEFSFGG
EEECCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA