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The map label for this gene is queC

Identifier: 85058654

GI number: 85058654

Start: 1144704

End: 1145399

Strand: Reverse

Name: queC

Synonym: SG0676

Alternate gene names: 85058654

Gene position: 1145399-1144704 (Counterclockwise)

Preceding gene: 85058659

Following gene: 85058646

Centisome position: 27.46

GC content: 58.91

Gene sequence:

>696_bases
ATGAAACGAGCAGTGGTGGTGTTTAGCGGCGGACAGGACTCAACAACCTGCCTTATTCAGGCGTTAAGTCAGTATGACGA
AGTCCATTGCGTCACCTTTGACTATGGCCAACGCCATCGGGCGGAGATCGACGTCGCCCGCAAACTGGCGATGCAATTAG
GCGCCCGCGCGCATAAAGTGATCGATGCGGGACTGCTTAATGCGCTGGCGGTCAGCAGCCTTACCCGCGACAACATTACG
TTTCCGGGTTACGAGGACAGCGCCGGCGGTCTGCCCAGCACCTTCGTCCCCGGCCGAAATATCCTGTTTTTGACCCTGGC
CGCCATTTACGCCTATCAGGTCGAGGCAAGCGCAGTCATCACCGGCGTTTGCGAGACGGATTTTTCCGGTTACCCCGATT
GCCGCGATAACTTTATCAAAGCGTTGAATGCCGCAGTCAATCTCGGGATGGCGCGCGAACTGAGCTTCGTTACGCCGCTG
ATGTGGCTGGACAAGGCCGAAACCTGGGCGCTGGCGGATTATTACCACCAGCTCGATCGGGTGCGCCATGATACGCTTAC
CTGCTACAACGGCATCAAAGGCGACGGCTGCGGCCAGTGCGCGGCCTGCCACCTGCGCACACACGGGCTGGCGGCGTACC
GTGCGCAGCCACAGGCGGTTATGGCCTCGCTTAAAGCCAAAACCGGCCTTCATTAA

Upstream 100 bases:

>100_bases
TAACGTCAGACCGTCGTCGGATTCTTCGCCGCCCGCTACTGTTCATCTGCTGGCAGAGACAGTACCCTATATCCTTTGCC
CTACAGAGTGAATGAAACAG

Downstream 100 bases:

>100_bases
GCGCAACACCCTAGCCATAAACGGCAGCGGCAGTCTGATGGCCCTAACGGCAATATCGCAGCCCTGAATCGTAACGAGGC
GGCGGCAAGGGCGACAACTT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKRAVVVFSGGQDSTTCLIQALSQYDEVHCVTFDYGQRHRAEIDVARKLAMQLGARAHKVIDAGLLNALAVSSLTRDNIT
FPGYEDSAGGLPSTFVPGRNILFLTLAAIYAYQVEASAVITGVCETDFSGYPDCRDNFIKALNAAVNLGMARELSFVTPL
MWLDKAETWALADYYHQLDRVRHDTLTCYNGIKGDGCGQCAACHLRTHGLAAYRAQPQAVMASLKAKTGLH

Sequences:

>Translated_231_residues
MKRAVVVFSGGQDSTTCLIQALSQYDEVHCVTFDYGQRHRAEIDVARKLAMQLGARAHKVIDAGLLNALAVSSLTRDNIT
FPGYEDSAGGLPSTFVPGRNILFLTLAAIYAYQVEASAVITGVCETDFSGYPDCRDNFIKALNAAVNLGMARELSFVTPL
MWLDKAETWALADYYHQLDRVRHDTLTCYNGIKGDGCGQCAACHLRTHGLAAYRAQPQAVMASLKAKTGLH
>Mature_231_residues
MKRAVVVFSGGQDSTTCLIQALSQYDEVHCVTFDYGQRHRAEIDVARKLAMQLGARAHKVIDAGLLNALAVSSLTRDNIT
FPGYEDSAGGLPSTFVPGRNILFLTLAAIYAYQVEASAVITGVCETDFSGYPDCRDNFIKALNAAVNLGMARELSFVTPL
MWLDKAETWALADYYHQLDRVRHDTLTCYNGIKGDGCGQCAACHLRTHGLAAYRAQPQAVMASLKAKTGLH

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=230, Percent_Identity=78.2608695652174, Blast_Score=381, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SODGM (Q2NV74)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454356.1
- ProteinModelPortal:   Q2NV74
- SMR:   Q2NV74
- STRING:   Q2NV74
- GeneID:   3868143
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0676
- NMPDR:   fig|343509.6.peg.1473
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   Q2NV74
- ProtClustDB:   PRK11106
- BioCyc:   SGLO343509:SG0676-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25152; Mature: 25152

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVVVFSGGQDSTTCLIQALSQYDEVHCVTFDYGQRHRAEIDVARKLAMQLGARAHKV
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHH
IDAGLLNALAVSSLTRDNITFPGYEDSAGGLPSTFVPGRNILFLTLAAIYAYQVEASAVI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHHE
TGVCETDFSGYPDCRDNFIKALNAAVNLGMARELSFVTPLMWLDKAETWALADYYHQLDR
EEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VRHDTLTCYNGIKGDGCGQCAACHLRTHGLAAYRAQPQAVMASLKAKTGLH
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRAVVVFSGGQDSTTCLIQALSQYDEVHCVTFDYGQRHRAEIDVARKLAMQLGARAHKV
CCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHH
IDAGLLNALAVSSLTRDNITFPGYEDSAGGLPSTFVPGRNILFLTLAAIYAYQVEASAVI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHHE
TGVCETDFSGYPDCRDNFIKALNAAVNLGMARELSFVTPLMWLDKAETWALADYYHQLDR
EEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VRHDTLTCYNGIKGDGCGQCAACHLRTHGLAAYRAQPQAVMASLKAKTGLH
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA