Click here to switch to the map view.

The map label for this gene is tcyB [H]

Identifier: 85058513

GI number: 85058513

Start: 930895

End: 931554

Strand: Reverse

Name: tcyB [H]

Synonym: SG0535

Alternate gene names: 85058513

Gene position: 931554-930895 (Counterclockwise)

Preceding gene: 85058514

Following gene: 85058511

Centisome position: 22.33

GC content: 52.73

Gene sequence:

>660_bases
ATGCCGCCATGGCTGCAATTGATGTACGACTCCTTTTGGCGTTTGTTTACAGCCGGGCTAATGTTTACCCTGCCGCTGGC
TCTGCTGTCATTTGTCGGCGGCCTGGTGCTGGGGTTTCTGGTGGCGCTGGTTCGTTTGTATGGCCCGCAACCGCTGAAAG
GGATCGCTGATTTTTATGTCTGGGTTATCCGGGGAACACCGCTGCTGGTGCAGCTGTTTTTGATTTTCTATGGTCTGCCG
AGCGCAGGCGTCACCCTCGACGCTTTTCCAGCGGCGCTTATTGGATTTACCTTGAGCGTCGGCGCTTATGGCTCGGAAAT
CATCCGCGGCGCTATTGTTTCGGTGCCCAAGGCACAATGGGAAGCCGCCTGGGCTATCGGGATGAATTCAACTCAGGCGA
TGCGCAGGGTTATTTTGCCCCAGTCGGTATTTGTTTCTATACCTCCTCTGGCCAATTCGTTTATCTCGTTGATAAAAGAC
ACATCGCTGGCGGCGGTGATTACTGTGCCGGAAATGTTTCTGGCCGCGCAACGCATTGTGTCAGTGACCTATGAGCCGTT
AATTCTTTATATCGAAGCGGCGGCAATTTATCTGCTGTTCAGTACGGTGCTCAGCAAAGTGCAAAATCGTCTTGAGGTCT
ATTTCCGCCGCTACGAATAA

Upstream 100 bases:

>100_bases
AGCCCTGGATGAAATTAAAGTCGACGGCACGTATAAAACTATTTCGCTGCGCTATTTCGGCCAGGACGTTTCTCAGTAAT
TTTTTTCGGGAGTCACACCG

Downstream 100 bases:

>100_bases
TGGCGTTCACGACAGTGGATGCAGCCAACCTTCTCCTCCGGCCGGTTTATGGGATCGCAACGGGCGCCTTCGCAAGGCGC
CCGTTTTCTGTCCCGCTAGC

Product: amino-acid ABC transporter permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPPWLQLMYDSFWRLFTAGLMFTLPLALLSFVGGLVLGFLVALVRLYGPQPLKGIADFYVWVIRGTPLLVQLFLIFYGLP
SAGVTLDAFPAALIGFTLSVGAYGSEIIRGAIVSVPKAQWEAAWAIGMNSTQAMRRVILPQSVFVSIPPLANSFISLIKD
TSLAAVITVPEMFLAAQRIVSVTYEPLILYIEAAAIYLLFSTVLSKVQNRLEVYFRRYE

Sequences:

>Translated_219_residues
MPPWLQLMYDSFWRLFTAGLMFTLPLALLSFVGGLVLGFLVALVRLYGPQPLKGIADFYVWVIRGTPLLVQLFLIFYGLP
SAGVTLDAFPAALIGFTLSVGAYGSEIIRGAIVSVPKAQWEAAWAIGMNSTQAMRRVILPQSVFVSIPPLANSFISLIKD
TSLAAVITVPEMFLAAQRIVSVTYEPLILYIEAAAIYLLFSTVLSKVQNRLEVYFRRYE
>Mature_218_residues
PPWLQLMYDSFWRLFTAGLMFTLPLALLSFVGGLVLGFLVALVRLYGPQPLKGIADFYVWVIRGTPLLVQLFLIFYGLPS
AGVTLDAFPAALIGFTLSVGAYGSEIIRGAIVSVPKAQWEAAWAIGMNSTQAMRRVILPQSVFVSIPPLANSFISLIKDT
SLAAVITVPEMFLAAQRIVSVTYEPLILYIEAAAIYLLFSTVLSKVQNRLEVYFRRYE

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=215, Percent_Identity=50.2325581395349, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1787030, Length=213, Percent_Identity=36.6197183098592, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788645, Length=219, Percent_Identity=32.4200913242009, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1788646, Length=212, Percent_Identity=33.0188679245283, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787087, Length=234, Percent_Identity=28.2051282051282, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082239, Length=208, Percent_Identity=33.1730769230769, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787086, Length=213, Percent_Identity=30.0469483568075, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786873, Length=173, Percent_Identity=35.2601156069364, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994930, Length=130, Percent_Identity=35.3846153846154, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786874, Length=212, Percent_Identity=24.5283018867925, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24232; Mature: 24101

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPWLQLMYDSFWRLFTAGLMFTLPLALLSFVGGLVLGFLVALVRLYGPQPLKGIADFYV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WVIRGTPLLVQLFLIFYGLPSAGVTLDAFPAALIGFTLSVGAYGSEIIRGAIVSVPKAQW
HHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EAAWAIGMNSTQAMRRVILPQSVFVSIPPLANSFISLIKDTSLAAVITVPEMFLAAQRIV
HHHHEECCCHHHHHHHHHCCHHHEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SVTYEPLILYIEAAAIYLLFSTVLSKVQNRLEVYFRRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPWLQLMYDSFWRLFTAGLMFTLPLALLSFVGGLVLGFLVALVRLYGPQPLKGIADFYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WVIRGTPLLVQLFLIFYGLPSAGVTLDAFPAALIGFTLSVGAYGSEIIRGAIVSVPKAQW
HHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EAAWAIGMNSTQAMRRVILPQSVFVSIPPLANSFISLIKDTSLAAVITVPEMFLAAQRIV
HHHHEECCCHHHHHHHHHCCHHHEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SVTYEPLILYIEAAAIYLLFSTVLSKVQNRLEVYFRRYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]