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The map label for this gene is speD

Identifier: 85058456

GI number: 85058456

Start: 832889

End: 833683

Strand: Reverse

Name: speD

Synonym: SG0478

Alternate gene names: 85058456

Gene position: 833683-832889 (Counterclockwise)

Preceding gene: 85058457

Following gene: 85058454

Centisome position: 19.99

GC content: 48.55

Gene sequence:

>795_bases
TTGCAGAAGCTAAAACTACACGGCTTTAATAACCTGACCAAGAGCCTGAGTTTTTGTATTTACGATATTTGCTATGCCAA
AACGGCGGACGACCGTGACGGCTATATCACCTACATTGACGAACAATATAACGCCAATCGTCTGACGGAAATTCTCAGCG
AAACCTGCTCCATGATAGGCGCCAATATCCTGAATATCGCCCGCCAGGACTACGAGCCGCAGGGTGCGAGCGTGACCATA
CTGGTGAGTGAGGAGCCGGTTGATCCGGGCAGCATTGACACGTCTGAACACCCTGGCCCGCTGCCGGAGTCGGTAGTGGC
ACATCTGGATAAAAGCCATATTTGCGTGCATACTTACCCGGAAAGCCATCCCGAGGGCGGTCTGTGCACCTTCCGCGCCG
ATATTGAGGTATCGACGTGCGGCGTCATTTCCCCGCTAAAAGCGCTCAATTACCTGATCCATCAGTTGGAGTCGGATATT
GTCACCATGGATTACCGCGTGCGCGGCTTCACCCGCGATATCAACGGGGTAAAACATTACATTGATCATGAAATCAATTC
GATTCAGAATTTCATGTCGAAAGATATGAAAGCGCTCTATCACATGATGGATGTGAATGTGTATCAGGAAAATATTTTTC
ATACCAAGATAATGCTGAAAGATTTTGATCTGAAACATTATCTGTTCAATGCCCGACCGGACGATCTCAGCGCCGAGGAG
CGTAAAGCGATTACCGACTTACTCTATAAAGAGATGCAGGAAATCTATTACGGCCGCAACTTGCCGGTGCTGTAA

Upstream 100 bases:

>100_bases
AATGCGGCGATCCATCACGGCAGCTTCGCCCTGCCGCAATATTTGCTGAATGCCTTATCAGCCTCCCGCTGAAACGGTAT
CCATAAGGGGGTGAACCAAA

Downstream 100 bases:

>100_bases
CCCCCCGCCGCTGCCAGCGTCCTGGTCTTCTACCCTGGTGGGGATCAGGGTCGGCTATCCCGGTGATATGCCTGCCGCCC
TGAGCGGGTGCAAAAGGGGA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYITYIDEQYNANRLTEILSETCSMIGANILNIARQDYEPQGASVTI
LVSEEPVDPGSIDTSEHPGPLPESVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTMDYRVRGFTRDINGVKHYIDHEINSIQNFMSKDMKALYHMMDVNVYQENIFHTKIMLKDFDLKHYLFNARPDDLSAEE
RKAITDLLYKEMQEIYYGRNLPVL

Sequences:

>Translated_264_residues
MQKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYITYIDEQYNANRLTEILSETCSMIGANILNIARQDYEPQGASVTI
LVSEEPVDPGSIDTSEHPGPLPESVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTMDYRVRGFTRDINGVKHYIDHEINSIQNFMSKDMKALYHMMDVNVYQENIFHTKIMLKDFDLKHYLFNARPDDLSAEE
RKAITDLLYKEMQEIYYGRNLPVL
>Mature_264_residues
MQKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYITYIDEQYNANRLTEILSETCSMIGANILNIARQDYEPQGASVTI
LVSEEPVDPGSIDTSEHPGPLPESVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTMDYRVRGFTRDINGVKHYIDHEINSIQNFMSKDMKALYHMMDVNVYQENIFHTKIMLKDFDLKHYLFNARPDDLSAEE
RKAITDLLYKEMQEIYYGRNLPVL

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786311, Length=264, Percent_Identity=85.9848484848485, Blast_Score=486, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPED_SODGM (Q2NVS2)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454158.1
- ProteinModelPortal:   Q2NVS2
- STRING:   Q2NVS2
- GeneID:   3868692
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0478
- NMPDR:   fig|343509.6.peg.1081
- eggNOG:   COG1586
- HOGENOM:   HBG303125
- OMA:   YNAERLT
- PhylomeDB:   Q2NVS2
- ProtClustDB:   PRK05462
- BioCyc:   SGLO343509:SG0478-MONOMER
- HAMAP:   MF_00465
- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067
- Gene3D:   G3DSA:3.60.90.10
- PIRSF:   PIRSF001356
- TIGRFAMs:   TIGR03331

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 30251; Mature: 30251

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: ACT_SITE 112-112 ACT_SITE 117-117 ACT_SITE 140-140

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYITYIDEQYNANRLTEILSETCSMIG
CCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ANILNIARQDYEPQGASVTILVSEEPVDPGSIDTSEHPGPLPESVVAHLDKSHICVHTYP
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECC
ESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTMDYRVRGFTRDINGVKHY
CCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHH
IDHEINSIQNFMSKDMKALYHMMDVNVYQENIFHTKIMLKDFDLKHYLFNARPDDLSAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHCCCCCCCCCHHH
RKAITDLLYKEMQEIYYGRNLPVL
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYITYIDEQYNANRLTEILSETCSMIG
CCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
ANILNIARQDYEPQGASVTILVSEEPVDPGSIDTSEHPGPLPESVVAHLDKSHICVHTYP
HHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECC
ESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTMDYRVRGFTRDINGVKHY
CCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHHH
IDHEINSIQNFMSKDMKALYHMMDVNVYQENIFHTKIMLKDFDLKHYLFNARPDDLSAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHCCCCCCCCCHHH
RKAITDLLYKEMQEIYYGRNLPVL
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA