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The map label for this gene is dipZ

Identifier: 85058279

GI number: 85058279

Start: 546822

End: 548594

Strand: Reverse

Name: dipZ

Synonym: SG0301

Alternate gene names: 85058279

Gene position: 548594-546822 (Counterclockwise)

Preceding gene: 85058280

Following gene: 85058278

Centisome position: 13.15

GC content: 60.01

Gene sequence:

>1773_bases
ATGGCTCAACGACGCTTTACGCTGATATTGCTGGCATGCCTGACGTGCCTGCCGCTGCTGCCCGCCCATGCCGCCTTGTT
CGGCAATTCTCACGGCAACCAGTTCATTCCTGCGGAACAGGCGTTTCGCTTCGACTTCCGCCAGCAGGGTTCGCAATTAA
CGCTAAGCTGGGACATCCATCCCGGCTACTATTTGTACCGCCAGCAGATCCGGCTGGAGCCGGTCAATGCGACCCTCGGA
GCTTTCACGTTGCCTGCCGGCAGCCGCCACCATGACGAATTTTATGGCGATGATGTAGCTATCTACCGCGATGAGCTGAA
TATTACGCTACCGTTGGCGCAGGCCCAAAACGACAGTCAGCTTCGCGTCACTTGGCAAGGCTGTGCGGAAGCGGGCTTTT
GCTATCCGCCGGAAACCCAGGTGATCCCGTTGTCGGCCATAGCCGCAGCACCGCCAAGCGGGACTGGTATAGGAAGCACC
GCCCTCATTCCGGCACCGCCGCCCGCCGGCGGCCAAGGCATTATTACTCCGGCGCCCCCGCCCCAAAGCAATAACCTGCC
CTTCTCCCCGCTGTGGGCTCTGCTTATTGGGATTGGTATCGCCTTCACACCCTGTGTGCTGCCGATGTATCCGCTGATTT
CCGCGGTGATTCTGGGCAACCGGCTGCAACTCAGCACCGCTCGGGTATTGCTGTTGGCCGTTGTCTACGTGATGGGAATG
GCCATCACCTACACGCTATTAGGTGTCGCAGTAGCCGCCGCCGGCCTGCAATTTCAGGCCGTGCTCCAACAGCCCGCCCT
GCTGATCGGGCTTGCCGCACTGTTTATTCTGTTGGCGTTGTCGATGTTCGGCGTCTTTACCCTGCAACTCCCCTCGGCGC
TACAGACCCATTTGGCGCTATGGAGCAACCGCCAGCGTCAGGGGACCTTACCCGGCGTCTTTATCATGGGCGCGCTGGCA
GGGCTGTTTTGTTCCCCTTGTACTACCGCGCCGCTGAGCGCCATTTTACTCTACATCGCCCAAAGCGGTAATCTGTGGTT
CAGCGGTTTCACCCTGTGGCTGTATGCGGTGGGGATGGGCATTCCTTTGATATTGGTCGCGCTGTTCGGCCATCGGCTGC
TACCCAAAAGAGGCCCCTGGATGCAGCAGGTCAAACAGGGATTCGGCTTCGTTATTCTGGCGCTGCCGGTGTTCTTGCTG
GAGCGTGTTCTGGGCGATAGCTGGGGCACGCGGCTCTGGAGCCTGCTGGGGGTAGCGTTTTTCGGCTGGGGCTTCCTGCT
GTGCCTGCAGGCCCGCTGGCGCGGCGCCCGGTGGTTGGCGGTGCTAATGCTGGGCCTGACCTTGATAAGCGCTCGGCCGC
TACAGGATTGGCTCTGGGGCGCACCGGCCGACATGACATCAACGACCGGCGCTGCTCCAGTGTTCCAGCCCGTGCAAACG
CTAGCGCAAATCACCCAGGCACTCAACGCCGCGCCCGGCAAGCCGGTGATGCTGGATCTGTACGCCGACTGGTGCGTGGC
CTGTAAAGAGTTTGATAAATATACCTTTCGCGATCCCGCCGTCGTAGAACAAATGAGCCGCTTCACTCTGCTCCAGGCGG
ATGTCACCGCCAATGCGCCGGTGCAAAGAATGCTGCTTGGCCAACTGCAGGTGATAGGTCTGCCGACGATTCTGTTTTTT
GATAGCCGCGGCCACGAAATACCCGGCTCGCGGCTAACCGGTTATATGAACGCGGCAGATTTTACGCGACATTTGCGGAA
ACTGGCCCCGTGA

Upstream 100 bases:

>100_bases
TGCAGCAAGCGGTGTTTGCACAAATCAAAGCCCATCATCCCTATCAAACCCCGGAGTTATTGGTCATGCCCGTCATAGGC
GGCGATCCCGATTATCTATC

Downstream 100 bases:

>100_bases
GCGACACTCAGGCAAGGCAACCGCCGGTTAACCAGCAGGAGGAAACGTGCAACGAGAACACATACGCGATCGGGCGCTAA
GCCTACTTGAACAATGCGGT

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MAQRRFTLILLACLTCLPLLPAHAALFGNSHGNQFIPAEQAFRFDFRQQGSQLTLSWDIHPGYYLYRQQIRLEPVNATLG
AFTLPAGSRHHDEFYGDDVAIYRDELNITLPLAQAQNDSQLRVTWQGCAEAGFCYPPETQVIPLSAIAAAPPSGTGIGST
ALIPAPPPAGGQGIITPAPPPQSNNLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGNRLQLSTARVLLLAVVYVMGM
AITYTLLGVAVAAAGLQFQAVLQQPALLIGLAALFILLALSMFGVFTLQLPSALQTHLALWSNRQRQGTLPGVFIMGALA
GLFCSPCTTAPLSAILLYIAQSGNLWFSGFTLWLYAVGMGIPLILVALFGHRLLPKRGPWMQQVKQGFGFVILALPVFLL
ERVLGDSWGTRLWSLLGVAFFGWGFLLCLQARWRGARWLAVLMLGLTLISARPLQDWLWGAPADMTSTTGAAPVFQPVQT
LAQITQALNAAPGKPVMLDLYADWCVACKEFDKYTFRDPAVVEQMSRFTLLQADVTANAPVQRMLLGQLQVIGLPTILFF
DSRGHEIPGSRLTGYMNAADFTRHLRKLAP

Sequences:

>Translated_590_residues
MAQRRFTLILLACLTCLPLLPAHAALFGNSHGNQFIPAEQAFRFDFRQQGSQLTLSWDIHPGYYLYRQQIRLEPVNATLG
AFTLPAGSRHHDEFYGDDVAIYRDELNITLPLAQAQNDSQLRVTWQGCAEAGFCYPPETQVIPLSAIAAAPPSGTGIGST
ALIPAPPPAGGQGIITPAPPPQSNNLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGNRLQLSTARVLLLAVVYVMGM
AITYTLLGVAVAAAGLQFQAVLQQPALLIGLAALFILLALSMFGVFTLQLPSALQTHLALWSNRQRQGTLPGVFIMGALA
GLFCSPCTTAPLSAILLYIAQSGNLWFSGFTLWLYAVGMGIPLILVALFGHRLLPKRGPWMQQVKQGFGFVILALPVFLL
ERVLGDSWGTRLWSLLGVAFFGWGFLLCLQARWRGARWLAVLMLGLTLISARPLQDWLWGAPADMTSTTGAAPVFQPVQT
LAQITQALNAAPGKPVMLDLYADWCVACKEFDKYTFRDPAVVEQMSRFTLLQADVTANAPVQRMLLGQLQVIGLPTILFF
DSRGHEIPGSRLTGYMNAADFTRHLRKLAP
>Mature_589_residues
AQRRFTLILLACLTCLPLLPAHAALFGNSHGNQFIPAEQAFRFDFRQQGSQLTLSWDIHPGYYLYRQQIRLEPVNATLGA
FTLPAGSRHHDEFYGDDVAIYRDELNITLPLAQAQNDSQLRVTWQGCAEAGFCYPPETQVIPLSAIAAAPPSGTGIGSTA
LIPAPPPAGGQGIITPAPPPQSNNLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGNRLQLSTARVLLLAVVYVMGMA
ITYTLLGVAVAAAGLQFQAVLQQPALLIGLAALFILLALSMFGVFTLQLPSALQTHLALWSNRQRQGTLPGVFIMGALAG
LFCSPCTTAPLSAILLYIAQSGNLWFSGFTLWLYAVGMGIPLILVALFGHRLLPKRGPWMQQVKQGFGFVILALPVFLLE
RVLGDSWGTRLWSLLGVAFFGWGFLLCLQARWRGARWLAVLMLGLTLISARPLQDWLWGAPADMTSTTGAAPVFQPVQTL
AQITQALNAAPGKPVMLDLYADWCVACKEFDKYTFRDPAVVEQMSRFTLLQADVTANAPVQRMLLGQLQVIGLPTILFFD
SRGHEIPGSRLTGYMNAADFTRHLRKLAP

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1790578, Length=590, Percent_Identity=58.4745762711864, Blast_Score=664, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBD_SODGM (Q2NW99)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_453981.1
- ProteinModelPortal:   Q2NW99
- STRING:   Q2NW99
- GeneID:   3868569
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0301
- NMPDR:   fig|343509.6.peg.709
- eggNOG:   COG4232
- HOGENOM:   HBG640883
- OMA:   HTDEYFG
- PhylomeDB:   Q2NW99
- ProtClustDB:   PRK00293
- BioCyc:   SGLO343509:SG0301-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00399
- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- PANTHER:   PTHR10438

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin; SSF52833 Thiordxn-like_fd

EC number: =1.8.1.8

Molecular weight: Translated: 64143; Mature: 64012

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcc4f590)-; HASH(0xcc02118)-; HASH(0xcb3383c)-; HASH(0xd64a51c)-; HASH(0xca98b44)-; HASH(0xd663c18)-; HASH(0x979f19c)-; HASH(0xcf8fcac)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRRFTLILLACLTCLPLLPAHAALFGNSHGNQFIPAEQAFRFDFRQQGSQLTLSWDIH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECC
PGYYLYRQQIRLEPVNATLGAFTLPAGSRHHDEFYGDDVAIYRDELNITLPLAQAQNDSQ
CCCCEEEHHHEEEECCCCCCCEECCCCCCCCCHHCCCCEEEEECCCEEEEEECCCCCCCE
LRVTWQGCAEAGFCYPPETQVIPLSAIAAAPPSGTGIGSTALIPAPPPAGGQGIITPAPP
EEEEEECCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCCCEEECCCCCCCCCEEECCCCC
PQSNNLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGNRLQLSTARVLLLAVVYVMGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AITYTLLGVAVAAAGLQFQAVLQQPALLIGLAALFILLALSMFGVFTLQLPSALQTHLAL
HHHHHHHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
WSNRQRQGTLPGVFIMGALAGLFCSPCTTAPLSAILLYIAQSGNLWFSGFTLWLYAVGMG
HCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
IPLILVALFGHRLLPKRGPWMQQVKQGFGFVILALPVFLLERVLGDSWGTRLWSLLGVAF
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FGWGFLLCLQARWRGARWLAVLMLGLTLISARPLQDWLWGAPADMTSTTGAAPVFQPVQT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHH
LAQITQALNAAPGKPVMLDLYADWCVACKEFDKYTFRDPAVVEQMSRFTLLQADVTANAP
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCC
VQRMLLGQLQVIGLPTILFFDSRGHEIPGSRLTGYMNAADFTRHLRKLAP
HHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHCH
>Mature Secondary Structure 
AQRRFTLILLACLTCLPLLPAHAALFGNSHGNQFIPAEQAFRFDFRQQGSQLTLSWDIH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECC
PGYYLYRQQIRLEPVNATLGAFTLPAGSRHHDEFYGDDVAIYRDELNITLPLAQAQNDSQ
CCCCEEEHHHEEEECCCCCCCEECCCCCCCCCHHCCCCEEEEECCCEEEEEECCCCCCCE
LRVTWQGCAEAGFCYPPETQVIPLSAIAAAPPSGTGIGSTALIPAPPPAGGQGIITPAPP
EEEEEECCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCCCEEECCCCCCCCCEEECCCCC
PQSNNLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGNRLQLSTARVLLLAVVYVMGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AITYTLLGVAVAAAGLQFQAVLQQPALLIGLAALFILLALSMFGVFTLQLPSALQTHLAL
HHHHHHHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
WSNRQRQGTLPGVFIMGALAGLFCSPCTTAPLSAILLYIAQSGNLWFSGFTLWLYAVGMG
HCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
IPLILVALFGHRLLPKRGPWMQQVKQGFGFVILALPVFLLERVLGDSWGTRLWSLLGVAF
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FGWGFLLCLQARWRGARWLAVLMLGLTLISARPLQDWLWGAPADMTSTTGAAPVFQPVQT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHH
LAQITQALNAAPGKPVMLDLYADWCVACKEFDKYTFRDPAVVEQMSRFTLLQADVTANAP
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCC
VQRMLLGQLQVIGLPTILFFDSRGHEIPGSRLTGYMNAADFTRHLRKLAP
HHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA