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The map label for this gene is prmA

Identifier: 85058129

GI number: 85058129

Start: 269215

End: 270096

Strand: Reverse

Name: prmA

Synonym: SG0151

Alternate gene names: 85058129

Gene position: 270096-269215 (Counterclockwise)

Preceding gene: 85058130

Following gene: 85058128

Centisome position: 6.48

GC content: 60.54

Gene sequence:

>882_bases
ATGCCTTGGATACAACTCAAAATCACCACCACCGGCCAACAGGCGGATACCCTAAGCGACGCGCTGACGGAAAGCGGGGC
GGTGTCGGTGACCTTTCAAGATACCCACGATGTCCCCGTATATGAGCCTCTACCGGGCGAGACGCGCCTGTGGGGCGATA
CCGATGTCATCGGCCTGTATGACGCCGCAACTGATATAGCGACGGTTTTGGACGTACTAAAGACCCATCCGCTGCTTGGC
GCCGATTTCACTTACAAAATCGAGCAGCTAGAGGATAAAGACTGGGAGCGGGAATGGATGGACAATTTTCATCCCATGCG
CTTCGGCGAACGGCTGTGGATTTGCCCCAGCTGGCGCCCGGTGCCGGACCCACAGGCGGTGAATGTGATGCTCGATCCTG
GCCTGGCTTTCGGTACCGGCACGCACCCGACCACCGCGCTATGCCTGCAATGGCTGGACGGTCTCGATCTGCGCGGCAAG
ACGGTTATCGATTTCGGCTGTGGTTCCGGCATTCTGGCCATCGCCGCCTTGAAGTTGGGCGCTGCGCACGCTGTCGGTAT
TGATATCGACCCGCAGGCGATTCTGGCCAGCCGCGACAACGCTCAGCGTAACGGTGTAGCGGAACTTTTGACGCTGTATC
TGCCGCAACAGCAGCCGCAAGACCTGCATGCCAACGTGGTGGTGGCGAACATCCTTGCCGGGCCTCTACGCGAGCTGGCA
CCGCTTATCATTGATTTGCCGCTGCCGGGCGGCTATCTGGGTCTGTCGGGCATCCTGGCCAGCCAGGCCGAAAGCGTGGC
ACAGGCCTATGCCGCAGCCTTCTCCCTCGATCCGGTGGCCGAAAAAGAGGAGTGGTGCCGGATTACCGGCACGCGACGCT
GA

Upstream 100 bases:

>100_bases
TATTGGCGCTGGCACTGAGCCTGCTGGCGGCGTTTCTGGCGGGCAACCGCTTCGAGCGCCCCGCCGCTGCCGCCGTTTAA
CCGTAATAATGAGAACCGCT

Downstream 100 bases:

>100_bases
AAACGAATCGCACTGCTGCGGGGAGCGCGCACAACGTTAAAGACGTAATGCACCACGGCGCGAATAGTGCACGCGGCGAC
GGGACCCGCTTCATCTTCCG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPWIQLKITTTGQQADTLSDALTESGAVSVTFQDTHDVPVYEPLPGETRLWGDTDVIGLYDAATDIATVLDVLKTHPLLG
ADFTYKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRPVPDPQAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLRGK
TVIDFGCGSGILAIAALKLGAAHAVGIDIDPQAILASRDNAQRNGVAELLTLYLPQQQPQDLHANVVVANILAGPLRELA
PLIIDLPLPGGYLGLSGILASQAESVAQAYAAAFSLDPVAEKEEWCRITGTRR

Sequences:

>Translated_293_residues
MPWIQLKITTTGQQADTLSDALTESGAVSVTFQDTHDVPVYEPLPGETRLWGDTDVIGLYDAATDIATVLDVLKTHPLLG
ADFTYKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRPVPDPQAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLRGK
TVIDFGCGSGILAIAALKLGAAHAVGIDIDPQAILASRDNAQRNGVAELLTLYLPQQQPQDLHANVVVANILAGPLRELA
PLIIDLPLPGGYLGLSGILASQAESVAQAYAAAFSLDPVAEKEEWCRITGTRR
>Mature_292_residues
PWIQLKITTTGQQADTLSDALTESGAVSVTFQDTHDVPVYEPLPGETRLWGDTDVIGLYDAATDIATVLDVLKTHPLLGA
DFTYKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRPVPDPQAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLRGKT
VIDFGCGSGILAIAALKLGAAHAVGIDIDPQAILASRDNAQRNGVAELLTLYLPQQQPQDLHANVVVANILAGPLRELAP
LIIDLPLPGGYLGLSGILASQAESVAQAYAAAFSLDPVAEKEEWCRITGTRR

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=79.8634812286689, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_SODGM (Q2NWP9)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_453831.1
- ProteinModelPortal:   Q2NWP9
- SMR:   Q2NWP9
- STRING:   Q2NWP9
- GeneID:   3868517
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0151
- NMPDR:   fig|343509.6.peg.320
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   Q2NWP9
- ProtClustDB:   PRK00517
- BioCyc:   SGLO343509:SG0151-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31814; Mature: 31682

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQLKITTTGQQADTLSDALTESGAVSVTFQDTHDVPVYEPLPGETRLWGDTDVIGLY
CCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEH
DAATDIATVLDVLKTHPLLGADFTYKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRP
HHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
VPDPQAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLRGKTVIDFGCGSGILAIAALKLG
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHC
AAHAVGIDIDPQAILASRDNAQRNGVAELLTLYLPQQQPQDLHANVVVANILAGPLRELA
CCEEEECCCCCHHHEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHC
PLIIDLPLPGGYLGLSGILASQAESVAQAYAAAFSLDPVAEKEEWCRITGTRR
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCC
>Mature Secondary Structure 
PWIQLKITTTGQQADTLSDALTESGAVSVTFQDTHDVPVYEPLPGETRLWGDTDVIGLY
CEEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEH
DAATDIATVLDVLKTHPLLGADFTYKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRP
HHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
VPDPQAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLRGKTVIDFGCGSGILAIAALKLG
CCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHC
AAHAVGIDIDPQAILASRDNAQRNGVAELLTLYLPQQQPQDLHANVVVANILAGPLRELA
CCEEEECCCCCHHHEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHC
PLIIDLPLPGGYLGLSGILASQAESVAQAYAAAFSLDPVAEKEEWCRITGTRR
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA