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The map label for this gene is sipD [H]

Identifier: 85057984

GI number: 85057984

Start: 10538

End: 11701

Strand: Reverse

Name: sipD [H]

Synonym: SG0006

Alternate gene names: 85057984

Gene position: 11701-10538 (Counterclockwise)

Preceding gene: 85057987

Following gene: NA

Centisome position: 0.28

GC content: 43.64

Gene sequence:

>1164_bases
TTGGCAACCGGAAAAACCTTTGTTGCATCAGGAGAAACCATGGTAGATACAATTTGCAGGACACACTCTCATATTATACA
CATGACCTTTTCCCATGCCGACAGCCTACAAAGCGAGGTGGTAAAAAAAGAGCTATTCCAAGAGAATGTTAATGATAATT
GTCTCGATCTCATTGATCAACTCGGTCAATTATCAAGTAAACATAGTGACTTGTATCGATTGAAAGCAGGAATAAAGACT
TTTAAGCAACTAATGGCAGGGGAACCCGGTTCGCGCGTTCAAGATATCCTTAAAAAGATCGAATTACTCTCCCCTTCTCT
AACAAGAATTGATTCATCGGAACCTGACAGTATTGAATCGCTAAAGAGAAGACAAAAAGAATCTGCTAAAGCTGCATCCG
AGTTGAGTGAAGCCCTGCAAGGGGAAATACGCAAAGAAAGTTTTATCAGGCAGAAGAACTATAACACCCTAAATCACATA
ATCGAGGAAGTAAAACAAGAACCAAACCTTGAGGAAGCGTATAATATTTATCTGAAAGATGAGACTCAGCTAACCTATTC
GGAATTCTGGGCGTCAATTGCCGCCACGATTGCCTCGATTAAAACAAACTATGTCGACTTTTATTCTTCACTGATGCTGC
AATATGCTGATTTCTACCAGGCCTATACCGAGCTACAATCCAAAGCAGCAGGTGCGGTCAGCGAAGGGAAAGACGGTAAT
TATATCAAGTGGGATAACGATGTAATGGATTCCGCTTTCAAGGAGTTTGAGAATAAAATTGCCAGCTTGAATAACAATCT
GGGCACGGTGCCGCAGTGGGACCAGTTAAGCGATACGGAGCATCAGCAGATGGCCGATACGTTAAAGCCCGCGTTTGCTG
TCGATATGGAGACCGGCAAAATCACCTTCGATCAATCGGCTCTCTCCGCTTGTCCCAAAAGTCCTTCGGGCGGCAGCGGG
AGCGGCAAAAGCGATGTCGATATGGCAAGCTATAATGCCTGGCTGGCAGCGTTTAATTCGATGGGAAATACTTTCCAGAG
TAATATGCAATCTTTTGCCCAACGATATACCCAAGCAAATAGCACCTTTGATAACCTGAATAAAGTTCTCAGTAGCTCCA
TCACGGCGTTACTGGAATGCGCCAAGGCGTTTCTGAGTAACTAA

Upstream 100 bases:

>100_bases
TGAAGGAGTGATTAGTGAAATCATATAAAAATCATTAAAAAAAGAATGTTTTTTTATATTTTCCATCGCGAAAAAAGAAG
ATAATTATTAACATGAATTT

Downstream 100 bases:

>100_bases
TCGATGACAACTCACCTAGGAATCGCAGGCGGGAACGCCCCTGCGATAACAAGGCCAGATCTTGAGCGTCACAACATCAG
CGTCACCTCTGGCGTTAATG

Product: putative effector protein

Products: NA

Alternate protein names: Salmonella invasion protein D [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MATGKTFVASGETMVDTICRTHSHIIHMTFSHADSLQSEVVKKELFQENVNDNCLDLIDQLGQLSSKHSDLYRLKAGIKT
FKQLMAGEPGSRVQDILKKIELLSPSLTRIDSSEPDSIESLKRRQKESAKAASELSEALQGEIRKESFIRQKNYNTLNHI
IEEVKQEPNLEEAYNIYLKDETQLTYSEFWASIAATIASIKTNYVDFYSSLMLQYADFYQAYTELQSKAAGAVSEGKDGN
YIKWDNDVMDSAFKEFENKIASLNNNLGTVPQWDQLSDTEHQQMADTLKPAFAVDMETGKITFDQSALSACPKSPSGGSG
SGKSDVDMASYNAWLAAFNSMGNTFQSNMQSFAQRYTQANSTFDNLNKVLSSSITALLECAKAFLSN

Sequences:

>Translated_387_residues
MATGKTFVASGETMVDTICRTHSHIIHMTFSHADSLQSEVVKKELFQENVNDNCLDLIDQLGQLSSKHSDLYRLKAGIKT
FKQLMAGEPGSRVQDILKKIELLSPSLTRIDSSEPDSIESLKRRQKESAKAASELSEALQGEIRKESFIRQKNYNTLNHI
IEEVKQEPNLEEAYNIYLKDETQLTYSEFWASIAATIASIKTNYVDFYSSLMLQYADFYQAYTELQSKAAGAVSEGKDGN
YIKWDNDVMDSAFKEFENKIASLNNNLGTVPQWDQLSDTEHQQMADTLKPAFAVDMETGKITFDQSALSACPKSPSGGSG
SGKSDVDMASYNAWLAAFNSMGNTFQSNMQSFAQRYTQANSTFDNLNKVLSSSITALLECAKAFLSN
>Mature_386_residues
ATGKTFVASGETMVDTICRTHSHIIHMTFSHADSLQSEVVKKELFQENVNDNCLDLIDQLGQLSSKHSDLYRLKAGIKTF
KQLMAGEPGSRVQDILKKIELLSPSLTRIDSSEPDSIESLKRRQKESAKAASELSEALQGEIRKESFIRQKNYNTLNHII
EEVKQEPNLEEAYNIYLKDETQLTYSEFWASIAATIASIKTNYVDFYSSLMLQYADFYQAYTELQSKAAGAVSEGKDGNY
IKWDNDVMDSAFKEFENKIASLNNNLGTVPQWDQLSDTEHQQMADTLKPAFAVDMETGKITFDQSALSACPKSPSGGSGS
GKSDVDMASYNAWLAAFNSMGNTFQSNMQSFAQRYTQANSTFDNLNKVLSSSITALLECAKAFLSN

Specific function: Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of sipA, sipB, and sipC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS). Localizes to the tip of the external secretion needle that is part of the TTSS apparatus (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the invasin protein D family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009483
- InterPro:   IPR013386 [H]

Pfam domain/function: PF06511 IpaD [H]

EC number: NA

Molecular weight: Translated: 43106; Mature: 42975

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00256 AKH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGKTFVASGETMVDTICRTHSHIIHMTFSHADSLQSEVVKKELFQENVNDNCLDLIDQ
CCCCCCEECCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGQLSSKHSDLYRLKAGIKTFKQLMAGEPGSRVQDILKKIELLSPSLTRIDSSEPDSIES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHH
LKRRQKESAKAASELSEALQGEIRKESFIRQKNYNTLNHIIEEVKQEPNLEEAYNIYLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHEEEECC
ETQLTYSEFWASIAATIASIKTNYVDFYSSLMLQYADFYQAYTELQSKAAGAVSEGKDGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YIKWDNDVMDSAFKEFENKIASLNNNLGTVPQWDQLSDTEHQQMADTLKPAFAVDMETGK
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHEEECCCCC
ITFDQSALSACPKSPSGGSGSGKSDVDMASYNAWLAAFNSMGNTFQSNMQSFAQRYTQAN
EEECHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STFDNLNKVLSSSITALLECAKAFLSN
CHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATGKTFVASGETMVDTICRTHSHIIHMTFSHADSLQSEVVKKELFQENVNDNCLDLIDQ
CCCCCEECCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGQLSSKHSDLYRLKAGIKTFKQLMAGEPGSRVQDILKKIELLSPSLTRIDSSEPDSIES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHH
LKRRQKESAKAASELSEALQGEIRKESFIRQKNYNTLNHIIEEVKQEPNLEEAYNIYLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHEEEECC
ETQLTYSEFWASIAATIASIKTNYVDFYSSLMLQYADFYQAYTELQSKAAGAVSEGKDGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YIKWDNDVMDSAFKEFENKIASLNNNLGTVPQWDQLSDTEHQQMADTLKPAFAVDMETGK
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHEEECCCCC
ITFDQSALSACPKSPSGGSGSGKSDVDMASYNAWLAAFNSMGNTFQSNMQSFAQRYTQAN
EEECHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STFDNLNKVLSSSITALLECAKAFLSN
CHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA