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The map label for this gene is tolC

Identifier: 162382800

GI number: 162382800

Start: 485666

End: 487177

Strand: Reverse

Name: tolC

Synonym: SG0266

Alternate gene names: 162382800

Gene position: 487177-485666 (Counterclockwise)

Preceding gene: 85058252

Following gene: 85058243

Centisome position: 11.68

GC content: 53.44

Gene sequence:

>1512_bases
ATGAAGAAACTGCTCCCCCTCCTTATTGGACTGAGTCTTGGTAGTTTCAGTGCAATGAGTCAGGCAGAAAATCTGCTACA
GGTGTATCAGCAGGCCAGATCCTCCAACCCGGATCTTCGCCGCTCCGCCGCCGATCGTGATGCAGCCTTTGAAAAGATTA
ATGAACAGCGCGCTCCGCTGCTGCCTCAATTGGGATTGGGAGTAGATTACACCTATACCCAGGGTTTTCGCGACAACCGT
GATATCAATTCTAATGAGTCAAGCACCGCGCTGCAGTTGACCCAGACCATTTTCGATATGTCCAAATGGCGTGCCCTGAC
CCTCCAGGAAAAAACGGCGGGTATTCAGGATGTCTCGTATCAAACGGACCAGCAATCGTTAATTATCAATACCGCTACCG
CCTATTTTAACGTATTGAACGCCATTGATACACTGTCATATACCGAGGCGCAGAAGCAGGCACTTTATCGCCAGTTGGAC
CAAACTACCCAGCGCTTTAACGTCGGTCTGGTCGCCATTACGGATGTGCAAAATGCTCGCTCGGAATATGACACCGTTCT
GGCTTCCGAAGTCAGAGCCCACAACGATCTGGATAATGCGCTGGAAGCACTGCGCCAGATTACCGGCATGGAATATCCGC
AATTGGCGACGCTTAATATCGCGAGTTTCAAGACCCAACACCCCGATGCGATCACCAGCCTGTTAAAAGAAGCGGAAAAC
CGCAACCTCAGCCTGTTATCGGCGCGCCTGTCGCAGGATTTGGCTCGTGAAGATATCCGTTACTATCAGGCAGGCCATTT
GCCGACTTTAGATCTTAACGCCTCGTCAACAGTCAGCAATAGCGACTACAATGGTTCGCGAAACAATTCTGTGACCAATC
CCAATAAGCATATCGGCGGCAACGCTATCGGCCTGAGTCTGAACGTGCCACTTTATAGCGGGGGATCCGTAACCTCCCAG
GTGAAGCAGGCGCAGTACAGTTTTGTCAGCGCCAGCGAACAGCTTGAAAGCGTGCATCGCTCTATGGTCATGACCCTGCG
TTCATCGTTTAACAACATATCTGCCTCCATCAGCAGTATTGCCGCCTATGAACAGGCGGTGGTGTCGGCGCAAAGCTCAC
TGGACGCGTCGGAAGCCGGCTACCAGGTGGGCACCCGCACTATCGTTGACGTGTTGGATGCCACCACAACGCTTTATGAT
CGCAAGCGGAATCTCTCCCAGGCGCGCTATCAATACCTGATCAATCAATTGAACCTGAAATACGCTCTCGGCACGCTAAA
CGAAACGGATTTGGTGACATTGAATAATACGCTCGGTAAAACGGTGCCGACCGATCCCCAGACGGTAGCACCGGAAAATG
CCTCGCAGGACGCCCGTGCCGATGGTACCGGTACGACGTCGCCTGGCGCCAGTGCTGCGCAAACGGCCTTTCAGCCGCGC
GCGGCCAGCGTGACGACCGCGCCAGCCACCGGCACCGGTCGCACTAGCGGACGTAATCGTTTCCAGCATTAA

Upstream 100 bases:

>100_bases
CGTTAAGCCACCTATTCCGTCCGGCAGTGTCTGCTAGAATTAGCCACTATTTTTCTAATAGCTCTACCATAGCAATTTTG
CTGTTTCAAAAGGAATGCAA

Downstream 100 bases:

>100_bases
GTTCTTTCCCGGCGGTCAGGGCGAACCTTTGCTTTCCCCTGACGGCCGCCGGCGCTTCCCGTTGCCCGTCACTGCCCGCG
GAGACGATCACAGGGAAGTG

Product: outer membrane channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKKLLPLLIGLSLGSFSAMSQAENLLQVYQQARSSNPDLRRSAADRDAAFEKINEQRAPLLPQLGLGVDYTYTQGFRDNR
DINSNESSTALQLTQTIFDMSKWRALTLQEKTAGIQDVSYQTDQQSLIINTATAYFNVLNAIDTLSYTEAQKQALYRQLD
QTTQRFNVGLVAITDVQNARSEYDTVLASEVRAHNDLDNALEALRQITGMEYPQLATLNIASFKTQHPDAITSLLKEAEN
RNLSLLSARLSQDLAREDIRYYQAGHLPTLDLNASSTVSNSDYNGSRNNSVTNPNKHIGGNAIGLSLNVPLYSGGSVTSQ
VKQAQYSFVSASEQLESVHRSMVMTLRSSFNNISASISSIAAYEQAVVSAQSSLDASEAGYQVGTRTIVDVLDATTTLYD
RKRNLSQARYQYLINQLNLKYALGTLNETDLVTLNNTLGKTVPTDPQTVAPENASQDARADGTGTTSPGASAAQTAFQPR
AASVTTAPATGTGRTSGRNRFQH

Sequences:

>Translated_503_residues
MKKLLPLLIGLSLGSFSAMSQAENLLQVYQQARSSNPDLRRSAADRDAAFEKINEQRAPLLPQLGLGVDYTYTQGFRDNR
DINSNESSTALQLTQTIFDMSKWRALTLQEKTAGIQDVSYQTDQQSLIINTATAYFNVLNAIDTLSYTEAQKQALYRQLD
QTTQRFNVGLVAITDVQNARSEYDTVLASEVRAHNDLDNALEALRQITGMEYPQLATLNIASFKTQHPDAITSLLKEAEN
RNLSLLSARLSQDLAREDIRYYQAGHLPTLDLNASSTVSNSDYNGSRNNSVTNPNKHIGGNAIGLSLNVPLYSGGSVTSQ
VKQAQYSFVSASEQLESVHRSMVMTLRSSFNNISASISSIAAYEQAVVSAQSSLDASEAGYQVGTRTIVDVLDATTTLYD
RKRNLSQARYQYLINQLNLKYALGTLNETDLVTLNNTLGKTVPTDPQTVAPENASQDARADGTGTTSPGASAAQTAFQPR
AASVTTAPATGTGRTSGRNRFQH
>Mature_503_residues
MKKLLPLLIGLSLGSFSAMSQAENLLQVYQQARSSNPDLRRSAADRDAAFEKINEQRAPLLPQLGLGVDYTYTQGFRDNR
DINSNESSTALQLTQTIFDMSKWRALTLQEKTAGIQDVSYQTDQQSLIINTATAYFNVLNAIDTLSYTEAQKQALYRQLD
QTTQRFNVGLVAITDVQNARSEYDTVLASEVRAHNDLDNALEALRQITGMEYPQLATLNIASFKTQHPDAITSLLKEAEN
RNLSLLSARLSQDLAREDIRYYQAGHLPTLDLNASSTVSNSDYNGSRNNSVTNPNKHIGGNAIGLSLNVPLYSGGSVTSQ
VKQAQYSFVSASEQLESVHRSMVMTLRSSFNNISASISSIAAYEQAVVSAQSSLDASEAGYQVGTRTIVDVLDATTTLYD
RKRNLSQARYQYLINQLNLKYALGTLNETDLVTLNNTLGKTVPTDPQTVAPENASQDARADGTGTTSPGASAAQTAFQPR
AASVTTAPATGTGRTSGRNRFQH

Specific function: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=479, Percent_Identity=71.1899791231733, Blast_Score=666, Evalue=0.0,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54836; Mature: 54836

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLPLLIGLSLGSFSAMSQAENLLQVYQQARSSNPDLRRSAADRDAAFEKINEQRAPL
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
LPQLGLGVDYTYTQGFRDNRDINSNESSTALQLTQTIFDMSKWRALTLQEKTAGIQDVSY
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCC
QTDQQSLIINTATAYFNVLNAIDTLSYTEAQKQALYRQLDQTTQRFNVGLVAITDVQNAR
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
SEYDTVLASEVRAHNDLDNALEALRQITGMEYPQLATLNIASFKTQHPDAITSLLKEAEN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHCC
RNLSLLSARLSQDLAREDIRYYQAGHLPTLDLNASSTVSNSDYNGSRNNSVTNPNKHIGG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NAIGLSLNVPLYSGGSVTSQVKQAQYSFVSASEQLESVHRSMVMTLRSSFNNISASISSI
CEEEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYEQAVVSAQSSLDASEAGYQVGTRTIVDVLDATTTLYDRKRNLSQARYQYLINQLNLK
HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALGTLNETDLVTLNNTLGKTVPTDPQTVAPENASQDARADGTGTTSPGASAAQTAFQPR
EEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
AASVTTAPATGTGRTSGRNRFQH
CCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLLPLLIGLSLGSFSAMSQAENLLQVYQQARSSNPDLRRSAADRDAAFEKINEQRAPL
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
LPQLGLGVDYTYTQGFRDNRDINSNESSTALQLTQTIFDMSKWRALTLQEKTAGIQDVSY
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCC
QTDQQSLIINTATAYFNVLNAIDTLSYTEAQKQALYRQLDQTTQRFNVGLVAITDVQNAR
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHH
SEYDTVLASEVRAHNDLDNALEALRQITGMEYPQLATLNIASFKTQHPDAITSLLKEAEN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHCC
RNLSLLSARLSQDLAREDIRYYQAGHLPTLDLNASSTVSNSDYNGSRNNSVTNPNKHIGG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NAIGLSLNVPLYSGGSVTSQVKQAQYSFVSASEQLESVHRSMVMTLRSSFNNISASISSI
CEEEEEEECCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYEQAVVSAQSSLDASEAGYQVGTRTIVDVLDATTTLYDRKRNLSQARYQYLINQLNLK
HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALGTLNETDLVTLNNTLGKTVPTDPQTVAPENASQDARADGTGTTSPGASAAQTAFQPR
EEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCC
AASVTTAPATGTGRTSGRNRFQH
CCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8801424 [H]