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The map label for this gene is ccmE1 [H]

Identifier: 84624516

GI number: 84624516

Start: 3209233

End: 3209703

Strand: Direct

Name: ccmE1 [H]

Synonym: XOO_2859

Alternate gene names: 84624516

Gene position: 3209233-3209703 (Clockwise)

Preceding gene: 84624515

Following gene: 84624517

Centisome position: 64.96

GC content: 64.33

Gene sequence:

>471_bases
ATGAATGCCACGCGCAAACAACGTCTGTGCTTGGTGATCGGCGTCCTTGCCGCCGCCGCGCTGGCCGTGACGCTCATCGT
GTTCGCGCTGCAGCGGAACATGAGCTATCTGTTTACCCCCAGCCAGGTACGCGCCGGCGCAGCGGCCGGCTATCAGCAGT
TCCGGCTCGGCGGCATGGTCAAGGCCGGCTCGATCCAGCGCGCGGCCGATTCGCTGAAAGTCAGCTTCACCGTCATCGAT
AAGAACGCCGCCACCCCGGTGGAGTACACCGGCATTCTTCCGGACCTGTTCCGCGACAACCAATCGGTCATCGCCAACGG
GCGCATGCAGGGCGGGCGCTTTGTCGCCAACGAAGTACTGGCCAAGCACGACGAAACCTACATGCCGAAGGAGTTGAAGG
ATGCGATGGCCGAGGGCCACCTCGGAAAACCGATCCCCGCCACCGCCGCACCGCTGACCACGCCGCGTTGA

Upstream 100 bases:

>100_bases
GACGTCGCCGCTTGCCGCGCGCACTGCGCGGCCAGCTGCAGCGGCAGGCACCGCGGCCTGCACGCGATCAACCCGCCCCA
GTGCTGGAGCGGGAGGCGCC

Downstream 100 bases:

>100_bases
TGCGCTTGTGGTTGGTGCCACGTCCATCGATGACTCCGTTCCGTTTCACTTGCGATTCGCCCATGACGCCTGAACTCGGC
CAGATCGCCTTGATCCTGGC

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 1; Heme chaperone CcmE 1 [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MNATRKQRLCLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGAAAGYQQFRLGGMVKAGSIQRAADSLKVSFTVID
KNAATPVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHLGKPIPATAAPLTTPR

Sequences:

>Translated_156_residues
MNATRKQRLCLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGAAAGYQQFRLGGMVKAGSIQRAADSLKVSFTVID
KNAATPVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHLGKPIPATAAPLTTPR
>Mature_156_residues
MNATRKQRLCLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGAAAGYQQFRLGGMVKAGSIQRAADSLKVSFTVID
KNAATPVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVLAKHDETYMPKELKDAMAEGHLGKPIPATAAPLTTPR

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=147, Percent_Identity=43.5374149659864, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 16732; Mature: 16732

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATRKQRLCLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGAAAGYQQFRLGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHCCEE
KAGSIQRAADSLKVSFTVIDKNAATPVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVL
CCCCHHHHHHCEEEEEEEEECCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCCHHHHHHH
AKHDETYMPKELKDAMAEGHLGKPIPATAAPLTTPR
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNATRKQRLCLVIGVLAAAALAVTLIVFALQRNMSYLFTPSQVRAGAAAGYQQFRLGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHCCEE
KAGSIQRAADSLKVSFTVIDKNAATPVEYTGILPDLFRDNQSVIANGRMQGGRFVANEVL
CCCCHHHHHHCEEEEEEEEECCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCCHHHHHHH
AKHDETYMPKELKDAMAEGHLGKPIPATAAPLTTPR
HHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]