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The map label for this gene is htpG [H]

Identifier: 84624031

GI number: 84624031

Start: 2633873

End: 2635777

Strand: Direct

Name: htpG [H]

Synonym: XOO_2374

Alternate gene names: 84624031

Gene position: 2633873-2635777 (Clockwise)

Preceding gene: 84624025

Following gene: 84624034

Centisome position: 53.31

GC content: 62.15

Gene sequence:

>1905_bases
ATGACCGTTGATACCGACAAGCAGACACTTGGCTTCCAGACCGAGGTCAAGCAGCTGCTGCAGCTGATGATCCATTCGTT
GTACTCGAACAAGGAAATCTTCCTGCGCGAGCTGGTCTCCAATGCCGCCGATGCCGCCGACAAGCTGCGCTTCGAAGCCT
TGGTCAAGCCCGAGCTGCTGGAAGGCAGCGGCGAGCTGCGCATCCGCGTCGATTACGACAAGGACGCGCGCACCGTCACC
ATCGACGACAACGGCATCGGCATGAGCCGCGAGGATGCGGTCTCGCACCTGGGCACGATCGCCAAGTCCGGCACCGCCGA
TTTCCTCAAGCACCTGAGCGGCGACCAGAAGAAGGACGCCAACCTGATCGGCCAGTTCGGGGTGGGGTTCTACAGCGCCT
TCATCGTCGCCGACCAGGTCGATGTGTACTCGCGTCGCGCCGGTCTGCCGGCCAGAGAAGGCGTTCACTGGTCTTCGCGT
GGCGAAGGCGAATTCGAAGTTGCCAGCGTCGACAAGCCCGAGCGCGGCACCCGCATTGTGCTGCATCTGAAGGACGGCGA
AGACACCTTCGCCGATGGCTGGACGCTGCGCGGCATCCTCAAGAAATACTCCGACCATATCGGCCTGCCGATCGAGATGC
GCAAGGAGCATTACGGCGAAGCCGCCGACAAGCCGGCAGAGCCCGAATGGGAAGCGGTCAACCGCGCCAGCGCGCTGTGG
ACGCGCCCCAAGTCCGAGATCAAGGACGAGGAGTATCAGGAGTTCTACAAGCACATCGCCCACGACGCGGGCAACCCGCT
GGCCTGGAGCCATAACAAGGTCGAAGGCAAGCTGGAATACACCTCGCTGCTGTTCGTGCCCGGCCGCGCACCGTTCGACC
TGTACCACCGCGATTCGGCCAAGGGCCTGAAGCTGTACGTGCAGCGCGTTTTCATCATGGACCAGGCCGAGCAGTTCCTG
CCGCTGTACCTGCGTTTCATCAAGGGCGTGGTGGATTCGTCGGACCTCTCGCTCAATGTCTCGCGCGAAATCCTGCAATC
CGGCCCGGTGGTCGATTCGATGAAGTCAGCGCTGACCAAGCGCTCGCTGGACATGCTGGAAAAGCTTGCCAAGGACAAGC
CGGACGACTACGCCACGTTCTGGCGCAACTTCGGCCAGGCATTGAAGGAAGGCCCGGCCGAGGATTATGCCAACCGCGAA
AAGATCGCCGGCCTGATGCGCTTCTCCTCCACGCATGACACCACCGGCGCGCAGAGCGTGGGCCTGGCCGATTATGTAAG
TCGTTTGGCCGAAGGCCAGGACAAGCTGTACTACCTCACCGGTGAGAGCTACGCGCAGATCAAGGACAGCCCGCATCTGG
AGGTATTCCGCAAGAAGGGCATCGAAGTGCTGCTGCTCACCGACCGCATCGACGAATGGCTGATGAGCTACCTCACCGAA
TTCGACGGCAAGTCGTTCGTGGACGTGGCACGCGGCGATCTGGACCTGGGCAAGCTGGATTCGGAAGAAGACAAGAAGGC
GCAGGAAGAAGTCGCCAAGTCCAAGGAGGGCCTGGCCTCGCGCATCAAGGCAGCGCTGGGCGAGGACGTGGCCGAAGTCC
GCGTCTCGCATCGCCTGACCGATTCCCCGGCGATCCTGGCCATCGGCCAGGGCGACCTGGGCCTGCAGATGCGCCAGCTG
CTGGAAGCCAGCGGCCAGGCGGTGCCGGAAAGCAAGCCGGTATTCGAATTCAACCCCACCCACCCGCTGATCGAAAAGCT
GGATGCGGAGCAGGATATGGACCGGTTTTGCGATCTGAGCCAGGTGCTGTTCGACCAGGCGGCGCTGGCGGCGGGCGACA
GCCTCAAGGACCCGGCCGGGTATGTGAAGCGGTTGAATAAGTTGTTGTTGGAGTTGTCGGTGTAA

Upstream 100 bases:

>100_bases
GACAGATTCGCTCGGGCCCGCCTTGAAAAATCGGCAGATGGCCGCATCCCCCAGGCCATCGGCCGCGTTGCGGCCTGGAC
CACCACGGAGCACGACCCCA

Downstream 100 bases:

>100_bases
GGCCTGCGACACATGTTGTAATACACCAAGATCGGCGCATGCGCCGGTCTTTTTCCTGACGCAACAGGTCCGAAAAATGT
CAATTACTCATAAGTCAGAA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELLEGSGELRIRVDYDKDARTVT
IDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPAREGVHWSSR
GEGEFEVASVDKPERGTRIVLHLKDGEDTFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALW
TRPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFL
PLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTKRSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANRE
KIAGLMRFSSTHDTTGAQSVGLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
FDGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGEDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQL
LEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFCDLSQVLFDQAALAAGDSLKDPAGYVKRLNKLLLELSV

Sequences:

>Translated_634_residues
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELLEGSGELRIRVDYDKDARTVT
IDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPAREGVHWSSR
GEGEFEVASVDKPERGTRIVLHLKDGEDTFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALW
TRPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFL
PLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTKRSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANRE
KIAGLMRFSSTHDTTGAQSVGLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
FDGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGEDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQL
LEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFCDLSQVLFDQAALAAGDSLKDPAGYVKRLNKLLLELSV
>Mature_633_residues
TVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELLEGSGELRIRVDYDKDARTVTI
DDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPAREGVHWSSRG
EGEFEVASVDKPERGTRIVLHLKDGEDTFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALWT
RPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFLP
LYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTKRSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREK
IAGLMRFSSTHDTTGAQSVGLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTEF
DGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGEDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQLL
EASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFCDLSQVLFDQAALAAGDSLKDPAGYVKRLNKLLLELSV

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=680, Percent_Identity=37.2058823529412, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI20149594, Length=682, Percent_Identity=36.8035190615836, Blast_Score=410, Evalue=1e-114,
Organism=Homo sapiens, GI155722983, Length=633, Percent_Identity=34.913112164297, Blast_Score=360, Evalue=3e-99,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=38.2926829268293, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI153792590, Length=410, Percent_Identity=38.2926829268293, Blast_Score=268, Evalue=1e-71,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=59.9358974358974, Blast_Score=778, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=38.4730538922156, Blast_Score=443, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17542208, Length=668, Percent_Identity=35.6287425149701, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115535205, Length=643, Percent_Identity=33.9035769828927, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI115535167, Length=440, Percent_Identity=35.9090909090909, Blast_Score=267, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=37.7218934911243, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6325016, Length=209, Percent_Identity=42.1052631578947, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=38.5401459854015, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=35.5457227138643, Blast_Score=390, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24586016, Length=650, Percent_Identity=34, Blast_Score=358, Evalue=5e-99,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70890; Mature: 70759

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELL
CCCCCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EGSGELRIRVDYDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDA
CCCCCEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
NLIGQFGVGFYSAFIVADQVDVYSRRAGLPAREGVHWSSRGEGEFEVASVDKPERGTRIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEECCCCCCCCCEEE
LHLKDGEDTFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALW
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TRPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSA
CCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHCCCCC
KGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCHHHHHHHHHH
RSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKIAGLMRFSSTHDTTGAQSV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCC
GLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
CHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGEDVAEVRVSHRLT
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DSPAILAIGQGDLGLQMRQLLEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFCDLS
CCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHH
QVLFDQAALAAGDSLKDPAGYVKRLNKLLLELSV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELL
CCCCCCHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EGSGELRIRVDYDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDA
CCCCCEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCH
NLIGQFGVGFYSAFIVADQVDVYSRRAGLPAREGVHWSSRGEGEFEVASVDKPERGTRIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEECCCCCCCCCEEE
LHLKDGEDTFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALW
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TRPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSA
CCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHCCCCC
KGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCHHHHHHHHHH
RSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKIAGLMRFSSTHDTTGAQSV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCC
GLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTE
CHHHHHHHHHCCCCCEEEEECCCHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGEDVAEVRVSHRLT
CCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DSPAILAIGQGDLGLQMRQLLEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFCDLS
CCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHH
QVLFDQAALAAGDSLKDPAGYVKRLNKLLLELSV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]