Click here to switch to the map view.

The map label for this gene is kefBC [H]

Identifier: 84623715

GI number: 84623715

Start: 2276284

End: 2278470

Strand: Direct

Name: kefBC [H]

Synonym: XOO_2058

Alternate gene names: 84623715

Gene position: 2276284-2278470 (Clockwise)

Preceding gene: 84623714

Following gene: 84623718

Centisome position: 46.08

GC content: 64.29

Gene sequence:

>2187_bases
ATGCGTCCATCGCACCTGTGGAGCCTGCGCAAGGAAATCTTCGGGCTGGGTACGTTGCAGATCGCGGTTTGCGCGCTGGT
GTTGACCGGCATCGGCATGCTGCTCGGCTTCGCACCACCGGTAGCCTTCGTCGCGGCGTCCGGTTTTGTGCTGACCTCCA
CCGCCGTGGTGATGCAGTTGTTGGCCGAGCGCGGTGACGTGGCCTTGCCGCCGGGGCAAAAGATCGTAGCGATTCTGCTA
TTCGAAGATCTGTTGATCGTGCCGTTGCTGGCGATCGTAGCCTGGATGGCTGCTAGCTGCGATCCGCAGGCCGCATCGCA
GCGCTGGCAGGGCATCGGCATCGGTCTGGCCTGCATCGTCGGCTTGCTGGTGGCCGGGCGTTGGCTGCTCAATCGGCTGT
TCCGCATTCTGGCTGCGTCCAAGGCGCGCGAGGTGATGACGGCTGCAGCATTGCTGGTGGTGTTGGGCGCGGCACTGTTG
ATGCAGGTGGCCGGGCTGTCGATGGCGATGGGGGCATTGCTGGCCGGCGTGCTGTTGTCCGAGTCCACGTTCCGGCATCA
GATCGAAGCGGATATCGAACCGTTTCGCGGCATCCTGCTGGGGCTGTTCTTTCTGGGTGTCGGCATGAGCCTGGATTTAC
GCGTGGTCGCGGCCGATTGGCGCTTGATCGTAGCGGGCGTGCTGGCTTTGATGGTGGGCAAGGGCGCATGCATCTACGCG
GTGGCGCGGCTGATGCGCAGCGACCATCGGCAGGCGCTGGATCGCGGCATGCTGATGGCGCAGGGCGGCGAGTTCGCATG
CGTGCTGTTTGCCGCCGCTTCGGCATCCGGTGTCATCGATGCGCAGGTCACCGCCAGCCTGACCGCTATCGTGGTGTTGT
CGATGGCACTGACGCCGTTGTTCGTGTTGCTGCAACGGCGGCTGACGCCGGCCGCGGCGGTCTCGCTGGATGGCGTGGAA
GAAGCCAGCGGGCAGACCGGCAGCGACTTGATCATCGGCTTCGGGCGCTTCGGGCAGGTCGCCAGTCAATCGCTGTTGGC
GCGCGACGTGGCTGTGACCATCATCGACAACGACATCGAGATGATGCAAAGCGCTGAAGAGTTGGGCTTCAAGATCTACT
ACGGCGACGGCCCCGGCTGGACGTGTTGCATGCCTCCGGCGCGCACAGCGCACGCGCGATGTGGTCTGCGTCGACAACCA
GGAGGCGGCCAATCGCATCGTCGAACTGGCAACGCGCGAGTTTCCGCATGCCAAGCTGCTGGTGCGTTCCTACGATCGCC
AGCATTCGCTGCAACTGGTGGCTGCGGGCGTGGATTACCAGATCCGCGAGACCTTCGAGTCGGCGGTGATCTTCGGCAGA
GTCGCGCTGGAGGAACCGGGGATGGACGAGGACCAAGCCGGCATGATTTCGCGCCATATTCGTCGGCGCGATGCCGAGCG
TTCCGAATTGGAGATCGCTGCCGGCGATGCACGCGCCGGAGCCGGGCTGATGTACGGCAACACGTTGCCAGCCGCGCCCC
GGCCCACACCGTTCACGCGACCGCGTCGCGGCAGCCGCACGCTCAATCCCGATGCGGTGCCGTAAGCCGAGCAAGTAGAG
ACAGCGATACGCGAGTAAGAGCGGCGAACGAAACCACTGCGCAGGCGCCAGGCAGGTGCGGCCGGCGTCGGTGGGCATTT
ACCACTCATCCGCCTCGGCTTGTGCGCGCCGTATGCACCTATCTGACGACTGCTCGCTACTTGGTCGCCCCTGAAAAACC
CTCTCAAACACCAAATGCCATGTTTGCCGGCCACATGATGCTTGAGCGCGTTGAGGGGCGCGCCCGCACCACCTGCAACC
AGGCACGCAAAAAGGCGATCCAGCGCAGCCGCCACCGCAGGTTGTCGCCAGCGGCGCAGCCGAGCACGTGCAGTGCATCG
CCTTGGGCGCCTTTGAGATGGCAGCGATTCAAGCGGCAGTCCTGTTTCAGATGTCCGATCACCGGCTCTACCGCTTGCCG
TCGTTTGATCCAGCGCCATTGCCGTCGTGTCAGCGTCTTGGCTTTGCCCCGATGCAGGATCTGCACACCCTCCACGTCGC
GCCCGCGATACCCCAAGTCCACGATCGCCACCTTCGGGATCACATTCACATCCTGCAGCAGCCCGCGCGCCTGTTCCAGT
TGCTCGGCCAACGTATCGCCGTCGTAG

Upstream 100 bases:

>100_bases
GTCCGTTTGGGGTAGGCCTGTTCGACGAACCGCAAGCAATCCTGCATGTCGCCGAGTCGGGCGTGGTGATGTTCCTGTTC
CTGTTCGTGATCGGGCTGAA

Downstream 100 bases:

>100_bases
GGATGACCGGGAAAACTGCGCGCGCCCACGATCAAGCCCTTGCGCGCACTCACCGCAATGCCGACCTTGACGCCACATTC
GTAGGGGCTGCGTGCCTTGC

Product: hypothetical protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MRPSHLWSLRKEIFGLGTLQIAVCALVLTGIGMLLGFAPPVAFVAASGFVLTSTAVVMQLLAERGDVALPPGQKIVAILL
FEDLLIVPLLAIVAWMAASCDPQAASQRWQGIGIGLACIVGLLVAGRWLLNRLFRILAASKAREVMTAAALLVVLGAALL
MQVAGLSMAMGALLAGVLLSESTFRHQIEADIEPFRGILLGLFFLGVGMSLDLRVVAADWRLIVAGVLALMVGKGACIYA
VARLMRSDHRQALDRGMLMAQGGEFACVLFAAASASGVIDAQVTASLTAIVVLSMALTPLFVLLQRRLTPAAAVSLDGVE
EASGQTGSDLIIGFGRFGQVASQSLLARDVAVTIIDNDIEMMQSAEELGFKIYYGDGPGWTCCMPPARTAHARCGLRRQP
GGGQSHRRTGNARVSACQAAGAFLRSPAFAATGGCGRGLPDPRDLRVGGDLRQSRAGGTGDGRGPSRHDFAPYSSARCRA
FRIGDRCRRCTRRSRADVRQHVASRAPAHTVHATASRQPHAQSRCGAVSRASRDSDTRVRAANETTAQAPGRCGRRRWAF
TTHPPRLVRAVCTYLTTARYLVAPEKPSQTPNAMFAGHMMLERVEGRARTTCNQARKKAIQRSRHRRLSPAAQPSTCSAS
PWAPLRWQRFKRQSCFRCPITGSTACRRLIQRHCRRVSVLALPRCRICTPSTSRPRYPKSTIATFGITFTSCSSPRACSS
CSANVSPS

Sequences:

>Translated_728_residues
MRPSHLWSLRKEIFGLGTLQIAVCALVLTGIGMLLGFAPPVAFVAASGFVLTSTAVVMQLLAERGDVALPPGQKIVAILL
FEDLLIVPLLAIVAWMAASCDPQAASQRWQGIGIGLACIVGLLVAGRWLLNRLFRILAASKAREVMTAAALLVVLGAALL
MQVAGLSMAMGALLAGVLLSESTFRHQIEADIEPFRGILLGLFFLGVGMSLDLRVVAADWRLIVAGVLALMVGKGACIYA
VARLMRSDHRQALDRGMLMAQGGEFACVLFAAASASGVIDAQVTASLTAIVVLSMALTPLFVLLQRRLTPAAAVSLDGVE
EASGQTGSDLIIGFGRFGQVASQSLLARDVAVTIIDNDIEMMQSAEELGFKIYYGDGPGWTCCMPPARTAHARCGLRRQP
GGGQSHRRTGNARVSACQAAGAFLRSPAFAATGGCGRGLPDPRDLRVGGDLRQSRAGGTGDGRGPSRHDFAPYSSARCRA
FRIGDRCRRCTRRSRADVRQHVASRAPAHTVHATASRQPHAQSRCGAVSRASRDSDTRVRAANETTAQAPGRCGRRRWAF
TTHPPRLVRAVCTYLTTARYLVAPEKPSQTPNAMFAGHMMLERVEGRARTTCNQARKKAIQRSRHRRLSPAAQPSTCSAS
PWAPLRWQRFKRQSCFRCPITGSTACRRLIQRHCRRVSVLALPRCRICTPSTSRPRYPKSTIATFGITFTSCSSPRACSS
CSANVSPS
>Mature_728_residues
MRPSHLWSLRKEIFGLGTLQIAVCALVLTGIGMLLGFAPPVAFVAASGFVLTSTAVVMQLLAERGDVALPPGQKIVAILL
FEDLLIVPLLAIVAWMAASCDPQAASQRWQGIGIGLACIVGLLVAGRWLLNRLFRILAASKAREVMTAAALLVVLGAALL
MQVAGLSMAMGALLAGVLLSESTFRHQIEADIEPFRGILLGLFFLGVGMSLDLRVVAADWRLIVAGVLALMVGKGACIYA
VARLMRSDHRQALDRGMLMAQGGEFACVLFAAASASGVIDAQVTASLTAIVVLSMALTPLFVLLQRRLTPAAAVSLDGVE
EASGQTGSDLIIGFGRFGQVASQSLLARDVAVTIIDNDIEMMQSAEELGFKIYYGDGPGWTCCMPPARTAHARCGLRRQP
GGGQSHRRTGNARVSACQAAGAFLRSPAFAATGGCGRGLPDPRDLRVGGDLRQSRAGGTGDGRGPSRHDFAPYSSARCRA
FRIGDRCRRCTRRSRADVRQHVASRAPAHTVHATASRQPHAQSRCGAVSRASRDSDTRVRAANETTAQAPGRCGRRRWAF
TTHPPRLVRAVCTYLTTARYLVAPEKPSQTPNAMFAGHMMLERVEGRARTTCNQARKKAIQRSRHRRLSPAAQPSTCSAS
PWAPLRWQRFKRQSCFRCPITGSTACRRLIQRHCRRVSVLALPRCRICTPSTSRPRYPKSTIATFGITFTSCSSPRACSS
CSANVSPS

Specific function: Transport system that facilitate potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789749, Length=382, Percent_Identity=40.5759162303665, Blast_Score=246, Evalue=4e-66,
Organism=Escherichia coli, GI1786232, Length=380, Percent_Identity=37.6315789473684, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1786685, Length=414, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 78018; Mature: 78018

Theoretical pI: Translated: 11.48; Mature: 11.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSHLWSLRKEIFGLGTLQIAVCALVLTGIGMLLGFAPPVAFVAASGFVLTSTAVVMQL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
LAERGDVALPPGQKIVAILLFEDLLIVPLLAIVAWMAASCDPQAASQRWQGIGIGLACIV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
GLLVAGRWLLNRLFRILAASKAREVMTAAALLVVLGAALLMQVAGLSMAMGALLAGVLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTFRHQIEADIEPFRGILLGLFFLGVGMSLDLRVVAADWRLIVAGVLALMVGKGACIYA
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHH
VARLMRSDHRQALDRGMLMAQGGEFACVLFAAASASGVIDAQVTASLTAIVVLSMALTPL
HHHHHHHHHHHHHHHCCEEECCCCEEEEEEEHHCCCCCEEHHHHHHHHHHHHHHHHHHHH
FVLLQRRLTPAAAVSLDGVEEASGQTGSDLIIGFGRFGQVASQSLLARDVAVTIIDNDIE
HHHHHHHCCHHHHHCCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEECCHHH
MMQSAEELGFKIYYGDGPGWTCCMPPARTAHARCGLRRQPGGGQSHRRTGNARVSACQAA
HHHHHHHCCEEEEEECCCCCEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
GAFLRSPAFAATGGCGRGLPDPRDLRVGGDLRQSRAGGTGDGRGPSRHDFAPYSSARCRA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
FRIGDRCRRCTRRSRADVRQHVASRAPAHTVHATASRQPHAQSRCGAVSRASRDSDTRVR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEE
AANETTAQAPGRCGRRRWAFTTHPPRLVRAVCTYLTTARYLVAPEKPSQTPNAMFAGHMM
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHH
LERVEGRARTTCNQARKKAIQRSRHRRLSPAAQPSTCSASPWAPLRWQRFKRQSCFRCPI
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
TGSTACRRLIQRHCRRVSVLALPRCRICTPSTSRPRYPKSTIATFGITFTSCSSPRACSS
CCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHCEEEECCCCCCCCCC
CSANVSPS
CCCCCCCC
>Mature Secondary Structure
MRPSHLWSLRKEIFGLGTLQIAVCALVLTGIGMLLGFAPPVAFVAASGFVLTSTAVVMQL
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
LAERGDVALPPGQKIVAILLFEDLLIVPLLAIVAWMAASCDPQAASQRWQGIGIGLACIV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH
GLLVAGRWLLNRLFRILAASKAREVMTAAALLVVLGAALLMQVAGLSMAMGALLAGVLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTFRHQIEADIEPFRGILLGLFFLGVGMSLDLRVVAADWRLIVAGVLALMVGKGACIYA
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHH
VARLMRSDHRQALDRGMLMAQGGEFACVLFAAASASGVIDAQVTASLTAIVVLSMALTPL
HHHHHHHHHHHHHHHCCEEECCCCEEEEEEEHHCCCCCEEHHHHHHHHHHHHHHHHHHHH
FVLLQRRLTPAAAVSLDGVEEASGQTGSDLIIGFGRFGQVASQSLLARDVAVTIIDNDIE
HHHHHHHCCHHHHHCCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHEEEEECCHHH
MMQSAEELGFKIYYGDGPGWTCCMPPARTAHARCGLRRQPGGGQSHRRTGNARVSACQAA
HHHHHHHCCEEEEEECCCCCEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
GAFLRSPAFAATGGCGRGLPDPRDLRVGGDLRQSRAGGTGDGRGPSRHDFAPYSSARCRA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
FRIGDRCRRCTRRSRADVRQHVASRAPAHTVHATASRQPHAQSRCGAVSRASRDSDTRVR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCEEE
AANETTAQAPGRCGRRRWAFTTHPPRLVRAVCTYLTTARYLVAPEKPSQTPNAMFAGHMM
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHH
LERVEGRARTTCNQARKKAIQRSRHRRLSPAAQPSTCSASPWAPLRWQRFKRQSCFRCPI
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
TGSTACRRLIQRHCRRVSVLALPRCRICTPSTSRPRYPKSTIATFGITFTSCSSPRACSS
CCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHCEEEECCCCCCCCCC
CSANVSPS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]