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The map label for this gene is yafC [C]

Identifier: 84623651

GI number: 84623651

Start: 2198766

End: 2199779

Strand: Direct

Name: yafC [C]

Synonym: XOO_1994

Alternate gene names: 84623651

Gene position: 2198766-2199779 (Clockwise)

Preceding gene: 84623648

Following gene: 84623652

Centisome position: 44.51

GC content: 66.37

Gene sequence:

>1014_bases
ATGGATGCATGCGCCATGCACGACCTGAATGACCTGTACTACTTCGCGATGGTGGTGGACCACGGCGGCTTTGCCGCGGC
CGAGCGTGCGCTCGGGATCCCCAAATCGCGCCTGAGCCGGCGCATCAGCCAGCTTGAAACCGATCTGGGGGTGCGCCTGT
TGCAGCGCTCCACGCGCCGCTTCGCGGTCACCGACGTCGGCACCAGCGTGCATCGGCACGCACAGACCATGCTGGCCGAG
GCCCAGGCTGCGCGCGAGGTGGTGGATCGTCTCAGCGCCGAGCCGCGCGGTCTTGTACGTGTGAGCGTTCCAGTCTCGCT
CGCGCAGATCCAGTTGCCCAAGTTATTGCCCGAATTCCTGGCCAAATATCCCAAGGTGCGGCTACAGCTCAACATCAGCA
ACCGCCGCGTCGACGTCATCAACGAAGGCTACGACATTGCGCTACGCGTGCGGTCGCGCCTGGACGACGACGGCAGCCTG
GTGATGCGCAGCTTCGGCCAGGTGCAGGAGCTGCTGGTGGCCAGTCCCAAGTATCTGGACCGCGCCGGGCGCCCCAAGGA
CCCCAGCGAGCTGGCCAACCACACCACCATGAGCACCAGCGAGGACGAAGCCCACCAGCGCTGGGAACTGCATGGCCCCA
ACGGCGAACGCCGTGTCGACCTGCAGCCGCGCCTGGCCGGCTTCGATTTCCCGCTGTTGCAATCGATGGCACGCGACGGC
TTCGGCATCACCATGCTTCCGGAAACCGTGTGTGCCGAGGCGGTGCGCAGCGGCGAGCTGGAAGTGGTGCTGCCGCACTG
GTCGCTACCGCAGGGCATCTGCCACGCCGTGTTCGCCTCGCGTCGCGGTCTGCTGCCGGCGGTGCGGGTGTTCATCGATT
TCCTGGCCGAACACCTGCCCCAGGAAATCGAACGCTCGCGTCTGGATTGCGGTGGCACCTGCGCCGAACTGGCGGAGAAG
CTCAAGCGTGCGGCTGGCACGGCGCCGCGTTTGGTTGTGGCCGAAGCTGGCTGA

Upstream 100 bases:

>100_bases
TGACGGTGACCTGGGTAAGCGGCAGCGCCGCAGAGGTGTGCAGTCTAGGTCGTTGCTCTTTTGGGATAAAGTTGCTTAAA
TATAAATTATCGTTCTATTC

Downstream 100 bases:

>100_bases
GCGGTCGTGGCTGAAGCCGGTTCAGGGCTGTGTTTGGCTGCTGCGCTGGCTGCCCGACTGTTTGGAAACCCGCGAGCTGC
TCGGCCGTTAGTTCACTTCA

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDACAMHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTDVGTSVHRHAQTMLAE
AQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSL
VMRSFGQVQELLVASPKYLDRAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGERRVDLQPRLAGFDFPLLQSMARDG
FGITMLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIERSRLDCGGTCAELAEK
LKRAAGTAPRLVVAEAG

Sequences:

>Translated_337_residues
MDACAMHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTDVGTSVHRHAQTMLAE
AQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSL
VMRSFGQVQELLVASPKYLDRAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGERRVDLQPRLAGFDFPLLQSMARDG
FGITMLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIERSRLDCGGTCAELAEK
LKRAAGTAPRLVVAEAG
>Mature_337_residues
MDACAMHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTDVGTSVHRHAQTMLAE
AQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFLAKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSL
VMRSFGQVQELLVASPKYLDRAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGERRVDLQPRLAGFDFPLLQSMARDG
FGITMLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLPQEIERSRLDCGGTCAELAEK
LKRAAGTAPRLVVAEAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=30, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=28.8590604026846, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=29.8305084745763, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=25.7627118644068, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=29.0102389078498, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=24.8275862068966, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=27.2413793103448, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082132, Length=299, Percent_Identity=26.4214046822742, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=126, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787806, Length=175, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=27.34375, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37367; Mature: 37367

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDACAMHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRR
CCCCHHCCHHHHHEEHHHEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
FAVTDVGTSVHRHAQTMLAEAQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
AKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSFGQVQELLVASPKYLD
HHCCCEEEEEEECCCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
RAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGERRVDLQPRLAGFDFPLLQSMARDG
CCCCCCCHHHHHHCCCCCCCCHHHHHCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHCC
FGITMLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLP
CCEEECHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QEIERSRLDCGGTCAELAEKLKRAAGTAPRLVVAEAG
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure
MDACAMHDLNDLYYFAMVVDHGGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRR
CCCCHHCCHHHHHEEHHHEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
FAVTDVGTSVHRHAQTMLAEAQAAREVVDRLSAEPRGLVRVSVPVSLAQIQLPKLLPEFL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
AKYPKVRLQLNISNRRVDVINEGYDIALRVRSRLDDDGSLVMRSFGQVQELLVASPKYLD
HHCCCEEEEEEECCCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
RAGRPKDPSELANHTTMSTSEDEAHQRWELHGPNGERRVDLQPRLAGFDFPLLQSMARDG
CCCCCCCHHHHHHCCCCCCCCHHHHHCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHCC
FGITMLPETVCAEAVRSGELEVVLPHWSLPQGICHAVFASRRGLLPAVRVFIDFLAEHLP
CCEEECHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QEIERSRLDCGGTCAELAEKLKRAAGTAPRLVVAEAG
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]