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The map label for this gene is rnr [H]

Identifier: 84623616

GI number: 84623616

Start: 2165344

End: 2167770

Strand: Direct

Name: rnr [H]

Synonym: XOO_1959

Alternate gene names: 84623616

Gene position: 2165344-2167770 (Clockwise)

Preceding gene: 84623615

Following gene: 84623619

Centisome position: 43.83

GC content: 65.27

Gene sequence:

>2427_bases
ATGCCCGACTTCCTGGTCCGTGCCGCCGCCGGCGCGTCGACCAAGTCCGCCAACAAGCGCGCTGCCGACAAAGCTTCCAA
TGCTGCGTCGCAACCGCCGGCCGCCCTGCCAACGCCGCCGGCCCCGCGCGCACCGCATCCGCGCAAGAGTGGCCCACCTG
CGCCGCCGCCGGAACGCTTCCAGACCGCCGCGCCGCCCGCTGCTGCCGAATTCAAGGATCCGCACGCCGACCGCGAGGCC
CTGCGTTATGCAGAGCCGATCGCCAGTCGCGAAGCGATCCTGCAGCTGCTTGAAGCCTGCGACGGCCCGCAGACCGCTGA
AGAAATTGCCGAGCAGCTCAATCTGAGCGATCGCATCGATGCACTGGGCAAGCGCCTGGCCGCGATGGTGCGCGAAGCGC
AACTGGTGCAAAACCGCCGCGGCGGCTATGCGCCGGTGCAGCAGACCAGCCTGATCGCTGGGGTGGTGATCGCCAATCCG
GAGGGCTTCGGTTTCCTCAAGCCCGACGGCGGTGGCGATGACCTGTTCCTGCCGCCGTTCGAGATGCGCAAGGTCATGCA
CGGCGACCGCGCGTTGGCCAATGTCACCGGCATCGACCGCCGCGGCCGTCGCGAAGGTGCGATTGCGCGCGTGCTTGAGC
GGGGCATGTCGCGCATGCTGGGGCGCTTTTTCTATGAGCACGGCGTGGCTTACGTCGATCCCGATGACAAGCGCATCCAG
CGCAATGTGCAAATCGCCCCGGACGGTATCGGCGAGGCGCGCGAAGGCCAGTTGGTGGTTTGCGAACTGATCGCGCCGCC
GGACGCGCGCCGCCCGGCGATCGGCAAGATCATCGCGGTGCTTGGCGACAAGCTGACCCCGTCGCTGGTGGTGGAAATGG
CCATCCACGGCCACGAACTTCCGCACGAGTTCCCGCAGGAAGTGCTGGACGAAGCGGCGGCTGTGCCGTTGGTGGTCGAG
CCGCAGATGATCGGTGGGCGCGTGGATCTGCGGCAGATGCCGCTGGTCACCATCGACGGCGAAGACGCCAAGGATTTCGA
CGACGCGGTGTATTGCGAACCCAACGCCGACGGCTTCCGTCTGGTGGTGGCGATCGCCGACGTGTCCAACTATGTGCGTC
CCGGCACGCCGCTGGATGACGAAGCGCAAAAGCGCGCCACCTCGGTGTATTTCCCGGGATTCGTGGTGCCGATGCTGCCG
GAGACGCTGTCCAACGGCATCTGCTCGCTGATGCCCAAGGTCGATCGCATGTGTTTCGTCTGCGACATGCAGGTGGGAGG
CGATGGCGAAGTGACCGGCTCGCGTTTTTACGAAGCGGTGATGAACTCGCATGCGCGCCTGACCTACAACCAGGTGTGGA
AGGCGGTGGGCGAAGGCGATGCCGACACCAAGGCCTTCATCGGCCCGTTGCTGCCGCAAGTGCAGCGTCTGCATCAGCTG
TACCACGTGCTGTCGAAGGCGCGTACGCACCGTGGTGCGATCGAATTCGAAACCTCCGAAGTGCGCTTCGTGCTCGACAA
TACCGGCGAGGTCACCCAGGCCGGCATGCTGGTGCGCAACGATGCGCACAAGCTGATCGAAGAATGCATGATCGCCGCGA
ATGTCGAGGCGGCCCGCTACCTGCTGAGCATGCATGTGCCGGCGCCGTACCGTGTGCACGAGCGGCCGCCGGAGAGCAAG
TACGAAGACCTGCTGGAGTTCCTCAAGGAATTCCAGCTGAGCCTTCCCGCATGGAGCAAGGTGCGCCCCGGCGATTACAC
CAAGCTGCTGAAGAAGGTGCGTGCGCGTCCGGACGCGGCGTTGCTGGAATCGGTGCTGCTGCGCAGCCAGAGCCTGGCGG
TGTATTCGCCGGAAAATAACGGGCACTTCGGTCTGGCGTTGGAGGCGTACGCGCACTTCACCTCGCCGATCCGGCGTTAC
CCGGATCTGCTGGTGCATCGCGCGCTCAAGCACGCCTTGACCGGTGCCAGCCCGGAAAAATTCATCTACACCCCGCGTCA
GATGGCGGCGTTGTCGCTGCAGTGCTCCGAACGCGGCCGGCGTGCCGACGAAGCCGAGCGCGAAGTGGACGAGCGCTATC
GCGCCGCGTGGATGGAAAAGCATGTGGGTGGCCAGTTCGACGGCGTGATCAGCGGCGTGACCGGATTCGGTCTGTTCGTG
GAGTTGACGCAGTCCAAGGTCAATGGCCTGGTGCATGTCACCCAGCTGCCGCAGGACTATTACCAGTTCGACCCGATCCG
CAAGACGCTCAGTGGCGAACGCCGTGGTCGCGAATTCCGTCTGGGCGACCCGGTGCGCGTGCTGGTGCTCAAGGCCAGCA
TGGAAGGACGCAAGATCGACTTCCGCCTGGCCGAAGAGGGTGCAGCGCCCGAAGCGCCGCTGCCGCTGCGCGAAACGTCG
ACCAAGCGCAAGAAGAAATCGTCCTGA

Upstream 100 bases:

>100_bases
GACAAAGAAAAACACCCCAGATTCCAACCGGCCGAGTCGCCGTAAATCCACCAACGCAGGCGAGTCCAGCACCGCCGAGC
AGCAGAAGTTGCCAGGCTGG

Downstream 100 bases:

>100_bases
GGTGATGGCATTGCGGGCGGCCGAGATGGCGGCCAGCAATGCGGTGCAGGAGTAAGCAAGAGCGTTCACCGCAACCTCGC
GAGTCGTACTCAGATGGGTG

Product: RNase R

Products: NA

Alternate protein names: RNase R; Protein vacB [H]

Number of amino acids: Translated: 808; Mature: 807

Protein sequence:

>808_residues
MPDFLVRAAAGASTKSANKRAADKASNAASQPPAALPTPPAPRAPHPRKSGPPAPPPERFQTAAPPAAAEFKDPHADREA
LRYAEPIASREAILQLLEACDGPQTAEEIAEQLNLSDRIDALGKRLAAMVREAQLVQNRRGGYAPVQQTSLIAGVVIANP
EGFGFLKPDGGGDDLFLPPFEMRKVMHGDRALANVTGIDRRGRREGAIARVLERGMSRMLGRFFYEHGVAYVDPDDKRIQ
RNVQIAPDGIGEAREGQLVVCELIAPPDARRPAIGKIIAVLGDKLTPSLVVEMAIHGHELPHEFPQEVLDEAAAVPLVVE
PQMIGGRVDLRQMPLVTIDGEDAKDFDDAVYCEPNADGFRLVVAIADVSNYVRPGTPLDDEAQKRATSVYFPGFVVPMLP
ETLSNGICSLMPKVDRMCFVCDMQVGGDGEVTGSRFYEAVMNSHARLTYNQVWKAVGEGDADTKAFIGPLLPQVQRLHQL
YHVLSKARTHRGAIEFETSEVRFVLDNTGEVTQAGMLVRNDAHKLIEECMIAANVEAARYLLSMHVPAPYRVHERPPESK
YEDLLEFLKEFQLSLPAWSKVRPGDYTKLLKKVRARPDAALLESVLLRSQSLAVYSPENNGHFGLALEAYAHFTSPIRRY
PDLLVHRALKHALTGASPEKFIYTPRQMAALSLQCSERGRRADEAEREVDERYRAAWMEKHVGGQFDGVISGVTGFGLFV
ELTQSKVNGLVHVTQLPQDYYQFDPIRKTLSGERRGREFRLGDPVRVLVLKASMEGRKIDFRLAEEGAAPEAPLPLRETS
TKRKKKSS

Sequences:

>Translated_808_residues
MPDFLVRAAAGASTKSANKRAADKASNAASQPPAALPTPPAPRAPHPRKSGPPAPPPERFQTAAPPAAAEFKDPHADREA
LRYAEPIASREAILQLLEACDGPQTAEEIAEQLNLSDRIDALGKRLAAMVREAQLVQNRRGGYAPVQQTSLIAGVVIANP
EGFGFLKPDGGGDDLFLPPFEMRKVMHGDRALANVTGIDRRGRREGAIARVLERGMSRMLGRFFYEHGVAYVDPDDKRIQ
RNVQIAPDGIGEAREGQLVVCELIAPPDARRPAIGKIIAVLGDKLTPSLVVEMAIHGHELPHEFPQEVLDEAAAVPLVVE
PQMIGGRVDLRQMPLVTIDGEDAKDFDDAVYCEPNADGFRLVVAIADVSNYVRPGTPLDDEAQKRATSVYFPGFVVPMLP
ETLSNGICSLMPKVDRMCFVCDMQVGGDGEVTGSRFYEAVMNSHARLTYNQVWKAVGEGDADTKAFIGPLLPQVQRLHQL
YHVLSKARTHRGAIEFETSEVRFVLDNTGEVTQAGMLVRNDAHKLIEECMIAANVEAARYLLSMHVPAPYRVHERPPESK
YEDLLEFLKEFQLSLPAWSKVRPGDYTKLLKKVRARPDAALLESVLLRSQSLAVYSPENNGHFGLALEAYAHFTSPIRRY
PDLLVHRALKHALTGASPEKFIYTPRQMAALSLQCSERGRRADEAEREVDERYRAAWMEKHVGGQFDGVISGVTGFGLFV
ELTQSKVNGLVHVTQLPQDYYQFDPIRKTLSGERRGREFRLGDPVRVLVLKASMEGRKIDFRLAEEGAAPEAPLPLRETS
TKRKKKSS
>Mature_807_residues
PDFLVRAAAGASTKSANKRAADKASNAASQPPAALPTPPAPRAPHPRKSGPPAPPPERFQTAAPPAAAEFKDPHADREAL
RYAEPIASREAILQLLEACDGPQTAEEIAEQLNLSDRIDALGKRLAAMVREAQLVQNRRGGYAPVQQTSLIAGVVIANPE
GFGFLKPDGGGDDLFLPPFEMRKVMHGDRALANVTGIDRRGRREGAIARVLERGMSRMLGRFFYEHGVAYVDPDDKRIQR
NVQIAPDGIGEAREGQLVVCELIAPPDARRPAIGKIIAVLGDKLTPSLVVEMAIHGHELPHEFPQEVLDEAAAVPLVVEP
QMIGGRVDLRQMPLVTIDGEDAKDFDDAVYCEPNADGFRLVVAIADVSNYVRPGTPLDDEAQKRATSVYFPGFVVPMLPE
TLSNGICSLMPKVDRMCFVCDMQVGGDGEVTGSRFYEAVMNSHARLTYNQVWKAVGEGDADTKAFIGPLLPQVQRLHQLY
HVLSKARTHRGAIEFETSEVRFVLDNTGEVTQAGMLVRNDAHKLIEECMIAANVEAARYLLSMHVPAPYRVHERPPESKY
EDLLEFLKEFQLSLPAWSKVRPGDYTKLLKKVRARPDAALLESVLLRSQSLAVYSPENNGHFGLALEAYAHFTSPIRRYP
DLLVHRALKHALTGASPEKFIYTPRQMAALSLQCSERGRRADEAEREVDERYRAAWMEKHVGGQFDGVISGVTGFGLFVE
LTQSKVNGLVHVTQLPQDYYQFDPIRKTLSGERRGREFRLGDPVRVLVLKASMEGRKIDFRLAEEGAAPEAPLPLRETST
KRKKKSS

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs. Required for the expression of virulence genes in enteroinvasive strains of E.coli [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=471, Percent_Identity=30.1486199575372, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI190014623, Length=471, Percent_Identity=30.1486199575372, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI134288890, Length=523, Percent_Identity=27.7246653919694, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI219521928, Length=453, Percent_Identity=26.0485651214128, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI19115966, Length=453, Percent_Identity=26.0485651214128, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI87082383, Length=730, Percent_Identity=48.6301369863014, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=650, Percent_Identity=30.1538461538462, Blast_Score=218, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI212645896, Length=545, Percent_Identity=27.7064220183486, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17553506, Length=505, Percent_Identity=27.1287128712871, Blast_Score=160, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=438, Percent_Identity=29.6803652968037, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649634, Length=440, Percent_Identity=30.2272727272727, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24654592, Length=437, Percent_Identity=29.0617848970252, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI19922976, Length=437, Percent_Identity=29.0617848970252, Blast_Score=153, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24654597, Length=437, Percent_Identity=29.0617848970252, Blast_Score=153, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 89094; Mature: 88963

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFLVRAAAGASTKSANKRAADKASNAASQPPAALPTPPAPRAPHPRKSGPPAPPPERF
CCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QTAAPPAAAEFKDPHADREALRYAEPIASREAILQLLEACDGPQTAEEIAEQLNLSDRID
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
ALGKRLAAMVREAQLVQNRRGGYAPVQQTSLIAGVVIANPEGFGFLKPDGGGDDLFLPPF
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEEEECCCCCEEECCCCCCCCCCCCCH
EMRKVMHGDRALANVTGIDRRGRREGAIARVLERGMSRMLGRFFYEHGVAYVDPDDKRIQ
HHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHH
RNVQIAPDGIGEAREGQLVVCELIAPPDARRPAIGKIIAVLGDKLTPSLVVEMAIHGHEL
CCCEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PHEFPQEVLDEAAAVPLVVEPQMIGGRVDLRQMPLVTIDGEDAKDFDDAVYCEPNADGFR
CHHHHHHHHHHHHCCCEEECCHHHCCCCCHHHCCEEEECCCCCCCCCCCEEECCCCCCEE
LVVAIADVSNYVRPGTPLDDEAQKRATSVYFPGFVVPMLPETLSNGICSLMPKVDRMCFV
EEEEEECHHHHCCCCCCCCHHHHHHHCEEECCCHHHHHCHHHHHCHHHHHHHHHCCEEEE
CDMQVGGDGEVTGSRFYEAVMNSHARLTYNQVWKAVGEGDADTKAFIGPLLPQVQRLHQL
EEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
YHVLSKARTHRGAIEFETSEVRFVLDNTGEVTQAGMLVRNDAHKLIEECMIAANVEAARY
HHHHHHHHHHCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLSMHVPAPYRVHERPPESKYEDLLEFLKEFQLSLPAWSKVRPGDYTKLLKKVRARPDAA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHH
LLESVLLRSQSLAVYSPENNGHFGLALEAYAHFTSPIRRYPDLLVHRALKHALTGASPEK
HHHHHHHCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FIYTPRQMAALSLQCSERGRRADEAEREVDERYRAAWMEKHVGGQFDGVISGVTGFGLFV
EEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ELTQSKVNGLVHVTQLPQDYYQFDPIRKTLSGERRGREFRLGDPVRVLVLKASMEGRKID
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHCHHHCCCCEECCCCEEEEEEEECCCCCEEE
FRLAEEGAAPEAPLPLRETSTKRKKKSS
EEECCCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
PDFLVRAAAGASTKSANKRAADKASNAASQPPAALPTPPAPRAPHPRKSGPPAPPPERF
CCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QTAAPPAAAEFKDPHADREALRYAEPIASREAILQLLEACDGPQTAEEIAEQLNLSDRID
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
ALGKRLAAMVREAQLVQNRRGGYAPVQQTSLIAGVVIANPEGFGFLKPDGGGDDLFLPPF
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEEEECCCCCEEECCCCCCCCCCCCCH
EMRKVMHGDRALANVTGIDRRGRREGAIARVLERGMSRMLGRFFYEHGVAYVDPDDKRIQ
HHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHH
RNVQIAPDGIGEAREGQLVVCELIAPPDARRPAIGKIIAVLGDKLTPSLVVEMAIHGHEL
CCCEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PHEFPQEVLDEAAAVPLVVEPQMIGGRVDLRQMPLVTIDGEDAKDFDDAVYCEPNADGFR
CHHHHHHHHHHHHCCCEEECCHHHCCCCCHHHCCEEEECCCCCCCCCCCEEECCCCCCEE
LVVAIADVSNYVRPGTPLDDEAQKRATSVYFPGFVVPMLPETLSNGICSLMPKVDRMCFV
EEEEEECHHHHCCCCCCCCHHHHHHHCEEECCCHHHHHCHHHHHCHHHHHHHHHCCEEEE
CDMQVGGDGEVTGSRFYEAVMNSHARLTYNQVWKAVGEGDADTKAFIGPLLPQVQRLHQL
EEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
YHVLSKARTHRGAIEFETSEVRFVLDNTGEVTQAGMLVRNDAHKLIEECMIAANVEAARY
HHHHHHHHHHCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LLSMHVPAPYRVHERPPESKYEDLLEFLKEFQLSLPAWSKVRPGDYTKLLKKVRARPDAA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHH
LLESVLLRSQSLAVYSPENNGHFGLALEAYAHFTSPIRRYPDLLVHRALKHALTGASPEK
HHHHHHHCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FIYTPRQMAALSLQCSERGRRADEAEREVDERYRAAWMEKHVGGQFDGVISGVTGFGLFV
EEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ELTQSKVNGLVHVTQLPQDYYQFDPIRKTLSGERRGREFRLGDPVRVLVLKASMEGRKID
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHCHHHCCCCEECCCCEEEEEEEECCCCCEEE
FRLAEEGAAPEAPLPLRETSTKRKKKSS
EEECCCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3058695; 1400189; 9603904 [H]