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The map label for this gene is bcd [H]

Identifier: 84623614

GI number: 84623614

Start: 2161537

End: 2162718

Strand: Direct

Name: bcd [H]

Synonym: XOO_1957

Alternate gene names: 84623614

Gene position: 2161537-2162718 (Clockwise)

Preceding gene: 84623610

Following gene: 84623615

Centisome position: 43.75

GC content: 62.27

Gene sequence:

>1182_bases
ATGGGGCTCAGCTCAGACCTGGAGTGGTGCGACGTGGATTTCAGCTTTACCGAAGAACAATTGATGATCCAGGATGTGGC
GCGCCGCATCGCGCAGGAAAAGATCGCGCCCAGCGCCGAGCAATTCGACCGTAGCGGCGAATTTCCGCTGGAAAATATCC
GCTTGCTGGGCGAAAACGGTCTGATGGGCATCGAGGTGCCGGTCGACTACGGCGGCGCCGGCATGGACCCGATCAGCTAT
GCGCTGGCGATGATCGAAATCGCCGCGGCCGATGGCGCGCACTCCACCATCGTCTCGGTCAACAACTCGCTGTTTTGCAC
CGGTATTCTGAAAAACGGCAGCGAAGCGCAGAAGCAGCTGTACGTGCGCGCGATCGCCGAGGGCACGCACATCGGTGCGT
TCGCGCTGACCGAGCCGCAGTCCGGCTCGGATGCTTCGGCAATGCGCTGCCGCGCGGTCAAGCAGGCCGATGGCAGCTTC
GTCATCAACGGCAAGAAGAGCTGGATCACCTCCGGCCCGGTGGCCAAATACATCGTGTTGTTCGCGGTGACCGAGCCGGA
CAAGGGCTCGCGCGGCATCACTGCGTTCATGGTCGACACCGATCGTGCCGGTTTCCATCGCGGCAAGACCGAGCCCAAGC
TCGGCATTCGTGCCTCGGCCACGTGCGAAATCGAGTTTGCCGATTACCTTGCGCAGCCCGATGAAGTGCTGGGTGTGGAA
GGCGAGGGCTTCAGGACCGCCATGAGCGTGCTGGATGCCGGGCGCATCGGTATTGCTTCGCAGGCGGTCGGTATCGCGCG
TGCGGCGTACGAAGCCACGTTGGCGTACGTCAAGGAACGCAAGGCGTTCGGCGCGGCGATCGGCACCTTCCAGATGACGC
AGGCCAAGATCGCCGACATGAAGTGCAAGCTGGATGCAGCGCTGCTGTTGACGCTGCGCGCGGCGTGGTTGAAGGGGCAG
AGGCAGACGTTCGGCACCGAAGCGGCGGTGGCCAAGCTCACTGCGTCCGAAGCGGCGATGTGGATCACCCATCAAGCGGT
GCAAATTCATGGCGGCATGGGGTATTCGAAAGAGATGCCGCTGGAGCGCTACTTCCGCGATGCCAAAATCACCGAAATTT
ACGAAGGCACCTCGGAAATCCAACGCCTGGTGATTGCGCGCGGCGAGACTGGCTTGCGCTGA

Upstream 100 bases:

>100_bases
TTCCAGATCCATGAATATCTCTATATCGCGATATGGAGATATTTTCGGTCCGGCGGCAGGTGCGGTCAACTACATACGCA
TGCGAATGGTTGGCGCTACA

Downstream 100 bases:

>100_bases
TGCACGCCGCGCTCCAGCGTTGCCGCCGCGCGCGGCAACGCTGGAGCGCTCTTCGCGATGCCACGATCACCGAAATCTAC
GAAGGCACTCTGGTCATCCG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MGLSSDLEWCDVDFSFTEEQLMIQDVARRIAQEKIAPSAEQFDRSGEFPLENIRLLGENGLMGIEVPVDYGGAGMDPISY
ALAMIEIAAADGAHSTIVSVNNSLFCTGILKNGSEAQKQLYVRAIAEGTHIGAFALTEPQSGSDASAMRCRAVKQADGSF
VINGKKSWITSGPVAKYIVLFAVTEPDKGSRGITAFMVDTDRAGFHRGKTEPKLGIRASATCEIEFADYLAQPDEVLGVE
GEGFRTAMSVLDAGRIGIASQAVGIARAAYEATLAYVKERKAFGAAIGTFQMTQAKIADMKCKLDAALLLTLRAAWLKGQ
RQTFGTEAAVAKLTASEAAMWITHQAVQIHGGMGYSKEMPLERYFRDAKITEIYEGTSEIQRLVIARGETGLR

Sequences:

>Translated_393_residues
MGLSSDLEWCDVDFSFTEEQLMIQDVARRIAQEKIAPSAEQFDRSGEFPLENIRLLGENGLMGIEVPVDYGGAGMDPISY
ALAMIEIAAADGAHSTIVSVNNSLFCTGILKNGSEAQKQLYVRAIAEGTHIGAFALTEPQSGSDASAMRCRAVKQADGSF
VINGKKSWITSGPVAKYIVLFAVTEPDKGSRGITAFMVDTDRAGFHRGKTEPKLGIRASATCEIEFADYLAQPDEVLGVE
GEGFRTAMSVLDAGRIGIASQAVGIARAAYEATLAYVKERKAFGAAIGTFQMTQAKIADMKCKLDAALLLTLRAAWLKGQ
RQTFGTEAAVAKLTASEAAMWITHQAVQIHGGMGYSKEMPLERYFRDAKITEIYEGTSEIQRLVIARGETGLR
>Mature_392_residues
GLSSDLEWCDVDFSFTEEQLMIQDVARRIAQEKIAPSAEQFDRSGEFPLENIRLLGENGLMGIEVPVDYGGAGMDPISYA
LAMIEIAAADGAHSTIVSVNNSLFCTGILKNGSEAQKQLYVRAIAEGTHIGAFALTEPQSGSDASAMRCRAVKQADGSFV
INGKKSWITSGPVAKYIVLFAVTEPDKGSRGITAFMVDTDRAGFHRGKTEPKLGIRASATCEIEFADYLAQPDEVLGVEG
EGFRTAMSVLDAGRIGIASQAVGIARAAYEATLAYVKERKAFGAAIGTFQMTQAKIADMKCKLDAALLLTLRAAWLKGQR
QTFGTEAAVAKLTASEAAMWITHQAVQIHGGMGYSKEMPLERYFRDAKITEIYEGTSEIQRLVIARGETGLR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=48.7870619946092, Blast_Score=330, Evalue=1e-90,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=40.7506702412869, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=37.5661375661376, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=37.467018469657, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=37.467018469657, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI226958414, Length=334, Percent_Identity=38.0239520958084, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI21361497, Length=362, Percent_Identity=38.3977900552486, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI76496475, Length=338, Percent_Identity=36.3905325443787, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4557235, Length=338, Percent_Identity=36.3905325443787, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=31.7333333333333, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=31.3157894736842, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI4503943, Length=392, Percent_Identity=30.6122448979592, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI7669494, Length=374, Percent_Identity=30.2139037433155, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI48976061, Length=295, Percent_Identity=30.5084745762712, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI211971008, Length=295, Percent_Identity=30.5084745762712, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38505218, Length=304, Percent_Identity=27.6315789473684, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=31.758530183727, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=28.7598944591029, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87082384, Length=261, Percent_Identity=28.735632183908, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081702, Length=370, Percent_Identity=25.4054054054054, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=40.8602150537634, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=35.4330708661417, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=37.467018469657, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=36.2903225806452, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17534899, Length=395, Percent_Identity=36.7088607594937, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=40.8163265306122, Blast_Score=214, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=33.509234828496, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=35.7954545454545, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=31.25, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=30.3430079155673, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=32, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=29.023746701847, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=333, Percent_Identity=32.4324324324324, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=35.0649350649351, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=27.7044854881267, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=238, Percent_Identity=31.5126050420168, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI86563383, Length=334, Percent_Identity=26.9461077844311, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=295, Percent_Identity=26.4406779661017, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=334, Percent_Identity=26.9461077844311, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531913, Length=174, Percent_Identity=30.4597701149425, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=47.5806451612903, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=44.3548387096774, Blast_Score=317, Evalue=7e-87,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=39.9463806970509, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=39.1534391534392, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI21355753, Length=387, Percent_Identity=35.6589147286822, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI281363737, Length=339, Percent_Identity=37.7581120943953, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=32.987012987013, Blast_Score=184, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 42360; Mature: 42229

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSSDLEWCDVDFSFTEEQLMIQDVARRIAQEKIAPSAEQFDRSGEFPLENIRLLGENG
CCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHEEEECCCC
LMGIEVPVDYGGAGMDPISYALAMIEIAAADGAHSTIVSVNNSLFCTGILKNGSEAQKQL
EEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHH
YVRAIAEGTHIGAFALTEPQSGSDASAMRCRAVKQADGSFVINGKKSWITSGPVAKYIVL
HHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEE
FAVTEPDKGSRGITAFMVDTDRAGFHRGKTEPKLGIRASATCEIEFADYLAQPDEVLGVE
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCEEEEEHHHHHCCCCCEECCC
GEGFRTAMSVLDAGRIGIASQAVGIARAAYEATLAYVKERKAFGAAIGTFQMTQAKIADM
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KCKLDAALLLTLRAAWLKGQRQTFGTEAAVAKLTASEAAMWITHQAVQIHGGMGYSKEMP
HHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCC
LERYFRDAKITEIYEGTSEIQRLVIARGETGLR
HHHHHCCCHHHHHHCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GLSSDLEWCDVDFSFTEEQLMIQDVARRIAQEKIAPSAEQFDRSGEFPLENIRLLGENG
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHEEEECCCC
LMGIEVPVDYGGAGMDPISYALAMIEIAAADGAHSTIVSVNNSLFCTGILKNGSEAQKQL
EEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHH
YVRAIAEGTHIGAFALTEPQSGSDASAMRCRAVKQADGSFVINGKKSWITSGPVAKYIVL
HHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEEE
FAVTEPDKGSRGITAFMVDTDRAGFHRGKTEPKLGIRASATCEIEFADYLAQPDEVLGVE
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCEEEEEHHHHHCCCCCEECCC
GEGFRTAMSVLDAGRIGIASQAVGIARAAYEATLAYVKERKAFGAAIGTFQMTQAKIADM
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KCKLDAALLLTLRAAWLKGQRQTFGTEAAVAKLTASEAAMWITHQAVQIHGGMGYSKEMP
HHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCC
LERYFRDAKITEIYEGTSEIQRLVIARGETGLR
HHHHHCCCHHHHHHCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]