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The map label for this gene is udg [H]

Identifier: 84623603

GI number: 84623603

Start: 2147699

End: 2149048

Strand: Direct

Name: udg [H]

Synonym: XOO_1946

Alternate gene names: 84623603

Gene position: 2147699-2149048 (Clockwise)

Preceding gene: 84623602

Following gene: 84623604

Centisome position: 43.47

GC content: 61.78

Gene sequence:

>1350_bases
ATGCGAGTTGCGATCTTTGGTACCGGTTATGTTGGTCTTGTCACCGGAACCTGTCTGGCCGAAGTCGGTCATCACGTTAT
CTGTGTAGACATCGATCGGGCGAAAGTTGATGGGCTCAATCGTGGGGTGATTCCCATCTATGAACCCGGCCTGGAGCCGA
TGGTGAAAGCCAATCACGCCTCTGGCCGGTTGCGCTTCACCACCGATGCTGCCGAGGCGATCGCGCATGGCGAAATCACC
TTTATCGCCGTGGGCACGCCGCCGGATGAAGACGGCAGCGCCGACCTGCAGTACGTGCTGGCGGTTGCGCGTACGGTGGG
CCGCCATATCGATGGGCCCGCGGTCGTGGTGAACAAATCCACCGTGCCGGTCGGCACCGCCGACAAGGTGCGCGTGGCGA
TCCAGGAAGAGCTGGATGCACGTGGCGTGGACCATGAGTTCGACGTGGTTTCCAACCCCGAGTTCCTCAAAGAAGGCGAT
GCGGTAGCCGACTGCATGCGTCCCGATCGCATCGTGATCGGGGCCAAGAAGCCGGCGGCCATTGCGCGGATGCGTCGTCT
GTACGCACCGTTCAATCGCAACCGCGATCGCATCGTGGAAATGGACGTGCGCTCGGCCGAGCTGACCAAGTACGCGGCCA
ACGCGATGCTGGCGACCAAGATCAGTTTCATGAACGAGATCGCCAATATTGCCGAGCGTGTTGGTGCGGACGTCGAGCAC
GTGCGTAACGGCATCGGCTCGGATCCGCGGATAGGCTGGCACTTCATCTATCCCGGCGCCGGTTACGGCGGCTCGTGCTT
CCCGAAGGACGTGCAGGCACTGGCCAAGACGGCCGAGCAGTACGGCATGCAGCCGACCCTGCTCAACGCAGTGGAAAGCG
TCAACAACGCGCAGAAGGGCCATCTGTTCGAACTGGTGCAGCGTCATTACGGCACCGAAGGCACTGGCAGCGTCGCTGGC
AAGACGTTTGCCGTTTGGGGTCTCGCGTTCAAGCCCAACACCGACGACATGCGTGCCGCGTCCAGCCGTCGCCTGATGGA
GCAGTTGTGGGAAGCCGGTGCCACCGTGCGCGCCTACGACCCGGAAGCCACCCATGAAGCCAAGCGCATCTTCGGCGAGC
GCGACGATCTGACCTTCTGCGACGATGCTTTTTCCGCACTGCAAGGCGCGGATGCACTGGTCGTAGTCACCGAGTGGAAG
CAGTTCCGCAGCCCTGACTTCGGCAAGATCAAGCAGGCACTGAAGGACGACGTCGTGTTTGACGGTCGCAACCTGTACGA
CCCGCAGGAAATCGAAGCCGCGGGTCTGGCGTACTACGCCATCGGACGAGGCCGTTCTTTGCATGCATGA

Upstream 100 bases:

>100_bases
CCGAACGGCACGCAGGGGATCGGACCTGACGCAACGTTGACGTTCGATGTTGAACTGATGGGTATCCTTCCCTGATCCCC
CCCTGAGAGTACCCCCACCC

Downstream 100 bases:

>100_bases
GCAACTCTCGCCGCGCGACCAGGCACTGGAAGCGCGGTTGGTTGAACTGGAAACGCGCCTCTCCTTTCAGGAGCAGGCGC
TTAACGAACTGAGTGAAGCA

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDRAKVDGLNRGVIPIYEPGLEPMVKANHASGRLRFTTDAAEAIAHGEIT
FIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPAVVVNKSTVPVGTADKVRVAIQEELDARGVDHEFDVVSNPEFLKEGD
AVADCMRPDRIVIGAKKPAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKGHLFELVQRHYGTEGTGSVAG
KTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRAYDPEATHEAKRIFGERDDLTFCDDAFSALQGADALVVVTEWK
QFRSPDFGKIKQALKDDVVFDGRNLYDPQEIEAAGLAYYAIGRGRSLHA

Sequences:

>Translated_449_residues
MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDRAKVDGLNRGVIPIYEPGLEPMVKANHASGRLRFTTDAAEAIAHGEIT
FIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPAVVVNKSTVPVGTADKVRVAIQEELDARGVDHEFDVVSNPEFLKEGD
AVADCMRPDRIVIGAKKPAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKGHLFELVQRHYGTEGTGSVAG
KTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRAYDPEATHEAKRIFGERDDLTFCDDAFSALQGADALVVVTEWK
QFRSPDFGKIKQALKDDVVFDGRNLYDPQEIEAAGLAYYAIGRGRSLHA
>Mature_449_residues
MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDRAKVDGLNRGVIPIYEPGLEPMVKANHASGRLRFTTDAAEAIAHGEIT
FIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPAVVVNKSTVPVGTADKVRVAIQEELDARGVDHEFDVVSNPEFLKEGD
AVADCMRPDRIVIGAKKPAAIARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKGHLFELVQRHYGTEGTGSVAG
KTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRAYDPEATHEAKRIFGERDDLTFCDDAFSALQGADALVVVTEWK
QFRSPDFGKIKQALKDDVVFDGRNLYDPQEIEAAGLAYYAIGRGRSLHA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=33.5456475583864, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI296040438, Length=373, Percent_Identity=34.3163538873995, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI296040443, Length=317, Percent_Identity=35.0157728706625, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=28.6082474226804, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI48994968, Length=445, Percent_Identity=28.7640449438202, Blast_Score=145, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17560350, Length=464, Percent_Identity=35.1293103448276, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI17136908, Length=474, Percent_Identity=32.7004219409283, Blast_Score=228, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48875; Mature: 48875

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDRAKVDGLNRGVIPIYEPGLEPMVKANHA
CEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHHCCCCCCCCCEEECCCCCHHHCCCCC
SGRLRFTTDAAEAIAHGEITFIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPAVVVNKS
CCEEEEECHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
TVPVGTADKVRVAIQEELDARGVDHEFDVVSNPEFLKEGDAVADCMRPDRIVIGAKKPAA
CCCCCCCHHEEEHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCEEEEECCCCHH
IARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEH
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKG
HHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
HLFELVQRHYGTEGTGSVAGKTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRAYD
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECC
PEATHEAKRIFGERDDLTFCDDAFSALQGADALVVVTEWKQFRSPDFGKIKQALKDDVVF
CHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCEEEEEECHHHHCCCCHHHHHHHHHHCEEE
DGRNLYDPQEIEAAGLAYYAIGRGRSLHA
CCCCCCCHHHHHHCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRVAIFGTGYVGLVTGTCLAEVGHHVICVDIDRAKVDGLNRGVIPIYEPGLEPMVKANHA
CEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHHCCCCCCCCCEEECCCCCHHHCCCCC
SGRLRFTTDAAEAIAHGEITFIAVGTPPDEDGSADLQYVLAVARTVGRHIDGPAVVVNKS
CCEEEEECHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECC
TVPVGTADKVRVAIQEELDARGVDHEFDVVSNPEFLKEGDAVADCMRPDRIVIGAKKPAA
CCCCCCCHHEEEHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCEEEEECCCCHH
IARMRRLYAPFNRNRDRIVEMDVRSAELTKYAANAMLATKISFMNEIANIAERVGADVEH
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRNGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALAKTAEQYGMQPTLLNAVESVNNAQKG
HHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
HLFELVQRHYGTEGTGSVAGKTFAVWGLAFKPNTDDMRAASSRRLMEQLWEAGATVRAYD
HHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECC
PEATHEAKRIFGERDDLTFCDDAFSALQGADALVVVTEWKQFRSPDFGKIKQALKDDVVF
CHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCEEEEEECHHHHCCCCHHHHHHHHHHCEEE
DGRNLYDPQEIEAAGLAYYAIGRGRSLHA
CCCCCCCHHHHHHCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]