Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 84623406

GI number: 84623406

Start: 1934330

End: 1935130

Strand: Direct

Name: lepB [H]

Synonym: XOO_1749

Alternate gene names: 84623406

Gene position: 1934330-1935130 (Clockwise)

Preceding gene: 84623405

Following gene: 84623407

Centisome position: 39.15

GC content: 58.68

Gene sequence:

>801_bases
ATGAAATGGTTTGAAATCATCTTGGTTGTCCTAACGCTCGGCAGTGGCTTCATCTGGCTGCTGGACAAGCTGTTTTTGGC
CAAGCACCGTGCCGCGCGTGCTGGTCTGCTGGACAGCGAGCCGGCGATCATCGATTACTCGCGCGCCTTTTTTCCCGTGC
TGGCGGTGGTGCTGATCCTGCGCAGCTTCGTGGCCGAGCCGTACAAGATTCCGTCCAGTTCGATGATGCCCAATCTATTG
ATCGGCGATTTCATCCTGGTCAACAAGTTCGCCTACGGTTTCCGTCTGCCGATCACCAATACCAAGTTCATTCCCACCGG
CGAGCCAAAGCGTGGCGATGTGGTGGTGTTCAAGCCGCCGCATGCGCCGGACCAGAACTGGATCAAGCGCGTGGTGGGCC
TGCCGGGCGACAAGATCGGCTTCCATGGCGATACCCTGTACATCAACGACAAGCCGATGCATTACACGGTCAAAGGCGAG
TACATCGGCAATGGCAAGGGCGCTGAAATGACCGGCACCACGCTGCTGGTCGAGTATCTACCGGGCCGCACGCATACCGT
GCTGGAGTGGCTGGACCGCAATATGCCGGCCGGGCAGGGCGACTGGACCGTGCCGGCGGACAGCTATTTCGTGATGGGGG
ATAATCGCGACAACAGCGAGGACAGTCGGTTTTGGACCCAGACGCACTTTCTGCCGGAAGCCAATCTGCGCGGCAAGGCG
TTCCTGATCTGGCTCAATTGCGAAGGGTGGTTCTGCAAGGGGAGTTTCGATCCATCGCGGATCGGGACTGGAATCCAGTA
A

Upstream 100 bases:

>100_bases
TTCGGGATTCGTCATTCGTGATTGGCAACGGCTTGCCCATCCTCTTGCTCTTAACTAATCCCGAATCTCAAATTTCGAAT
CCCGTTCCGAAGGAGCATCA

Downstream 100 bases:

>100_bases
ATCTAGGCACGGCGTGCCAGGGGAAGCACAATGAAGCGCAAGCAAAGCGGTATGACGTTGATGTCGTTCGTGGTGGTGGT
GGCGGTGGTGGGGTTCGGTC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKWFEIILVVLTLGSGFIWLLDKLFLAKHRAARAGLLDSEPAIIDYSRAFFPVLAVVLILRSFVAEPYKIPSSSMMPNLL
IGDFILVNKFAYGFRLPITNTKFIPTGEPKRGDVVVFKPPHAPDQNWIKRVVGLPGDKIGFHGDTLYINDKPMHYTVKGE
YIGNGKGAEMTGTTLLVEYLPGRTHTVLEWLDRNMPAGQGDWTVPADSYFVMGDNRDNSEDSRFWTQTHFLPEANLRGKA
FLIWLNCEGWFCKGSFDPSRIGTGIQ

Sequences:

>Translated_266_residues
MKWFEIILVVLTLGSGFIWLLDKLFLAKHRAARAGLLDSEPAIIDYSRAFFPVLAVVLILRSFVAEPYKIPSSSMMPNLL
IGDFILVNKFAYGFRLPITNTKFIPTGEPKRGDVVVFKPPHAPDQNWIKRVVGLPGDKIGFHGDTLYINDKPMHYTVKGE
YIGNGKGAEMTGTTLLVEYLPGRTHTVLEWLDRNMPAGQGDWTVPADSYFVMGDNRDNSEDSRFWTQTHFLPEANLRGKA
FLIWLNCEGWFCKGSFDPSRIGTGIQ
>Mature_266_residues
MKWFEIILVVLTLGSGFIWLLDKLFLAKHRAARAGLLDSEPAIIDYSRAFFPVLAVVLILRSFVAEPYKIPSSSMMPNLL
IGDFILVNKFAYGFRLPITNTKFIPTGEPKRGDVVVFKPPHAPDQNWIKRVVGLPGDKIGFHGDTLYINDKPMHYTVKGE
YIGNGKGAEMTGTTLLVEYLPGRTHTVLEWLDRNMPAGQGDWTVPADSYFVMGDNRDNSEDSRFWTQTHFLPEANLRGKA
FLIWLNCEGWFCKGSFDPSRIGTGIQ

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=302, Percent_Identity=39.4039735099338, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29972; Mature: 29972

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFEIILVVLTLGSGFIWLLDKLFLAKHRAARAGLLDSEPAIIDYSRAFFPVLAVVLIL
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHH
RSFVAEPYKIPSSSMMPNLLIGDFILVNKFAYGFRLPITNTKFIPTGEPKRGDVVVFKPP
HHHHCCCCCCCCCCCCCHHHHHHHHEEHHHHCEEECCCCCCEEECCCCCCCCCEEEECCC
HAPDQNWIKRVVGLPGDKIGFHGDTLYINDKPMHYTVKGEYIGNGKGAEMTGTTLLVEYL
CCCCHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
PGRTHTVLEWLDRNMPAGQGDWTVPADSYFVMGDNRDNSEDSRFWTQTHFLPEANLRGKA
CCCHHHHHHHHHCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEHEECCCCCCCCCCE
FLIWLNCEGWFCKGSFDPSRIGTGIQ
EEEEEECCCEEEECCCCHHHCCCCCC
>Mature Secondary Structure
MKWFEIILVVLTLGSGFIWLLDKLFLAKHRAARAGLLDSEPAIIDYSRAFFPVLAVVLIL
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHH
RSFVAEPYKIPSSSMMPNLLIGDFILVNKFAYGFRLPITNTKFIPTGEPKRGDVVVFKPP
HHHHCCCCCCCCCCCCCHHHHHHHHEEHHHHCEEECCCCCCEEECCCCCCCCCEEEECCC
HAPDQNWIKRVVGLPGDKIGFHGDTLYINDKPMHYTVKGEYIGNGKGAEMTGTTLLVEYL
CCCCHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
PGRTHTVLEWLDRNMPAGQGDWTVPADSYFVMGDNRDNSEDSRFWTQTHFLPEANLRGKA
CCCHHHHHHHHHCCCCCCCCCEECCCCCEEEEECCCCCCCCCEEEEHEECCCCCCCCCCE
FLIWLNCEGWFCKGSFDPSRIGTGIQ
EEEEEECCCEEEECCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]