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The map label for this gene is degP [H]

Identifier: 84623404

GI number: 84623404

Start: 1930666

End: 1932252

Strand: Direct

Name: degP [H]

Synonym: XOO_1747

Alternate gene names: 84623404

Gene position: 1930666-1932252 (Clockwise)

Preceding gene: 84623403

Following gene: 84623405

Centisome position: 39.08

GC content: 67.49

Gene sequence:

>1587_bases
ATGAACCATCGCATCCGCACCCAGATGTTCGGCCTGATCGCCATGACCCTGCCGCTGGCCGCCTGCGCGCAGCAGCCCGC
GCCCGCTGCCAAGGACGTCGCACCGATTGCCGCCAACCGCAGTGCCACGCCAGCGCCACAGCTGGTGGCGGGGCTGCCGG
ACTTCACCAATCTGGTCGAGCAGGTCGGCCCGGGCGTGGTCAATGTCGAAACCACCATCACCCGCAAGGACGCCATGGCG
CGTCAGCAGCGCAGTGGCCCGGGTGGTCGCGGCGGTGGCGCAATGCCCGATGACGATCAGATGCCGGAATTCTTCCGCCG
CTTCTTCGGTCCGGATTTCCAGATGCCGGGTGGGCCACGCCAGGGGCCGGGTGGTCCGGGGCAGGGCGATGACGACGGCG
GTATTGCCGGCAAGTCGATGGGCTCAGGCTTCATCATTTCCGCCGATGGCTATGTGCTGACCAATCATCACGTGGTCGAT
GGCGCCAGCGAAGTCACCGTCAAGCTCACCGACCGCCGCGAGTTCAAGGCCAAGGTGGTGGGGAGCGATGAGCAATACGA
CGTGGCGCTGCTGAAGATCGAGGCCAAGGGCCTGCCGACCGTGCGCCTGGGCGATTCCAATACGCTCAAGCCGGGCCAGT
GGGTGGTGGCGATCGGCTCGCCGTTCGGCCTGGACCACTCGGTCACCGCCGGCATCGTCAGTGCCACCGGCCGCAGCAAT
CCGTATGCGGATCAGCGCTACGTGCCCTTCATCCAGACCGACGTGGCGATCAACCAGGGTAATTCCGGCGGCCCGCTGCT
CAATACGCGCGGCGAAGTGGTCGGCATCAACTCGCAGATCTTCTCCGCGTCGGGCGGCTACATGGGCATTAGCTTTGCGA
TCCCGATCGACCTGGCCTTCAGTGCCGCCGAGCAGATCAAGGCCACTGGCCATGTGAGTCGCGGCATGCTGGGTGTGCAG
GTCGGCCCGATCGACTCGCTCAAGGCCCAGGGCCTGGGCTTGCCGGACAGCCGTGGTGCCTTGGTGAACGATATTCCGGC
CGGCAGCCCGGCGGGCAAGGCCGGTGTCGAAGTGGGCGATGTGATCCGCGCGGTCAACGGCAAGCCGATCGACGTCGCCA
GCGATCTGCCGCCGATGATCGGGCTGATGGCGCCGGGTTCCAAGGTCACTCTTGATGTCTTGCGCGACGGCAAACCGCGC
AAGGTGACGGTCACCCTCGCACCGCTCCAGGGTGGCAGCGAGAACGCCGCGCCGCGCACCGCGGCCGATGAGGCCAAGCC
CAGCGCCCCGGCCAGCGTGGAATTGCTCGGCCTGCAGGTCGCCGATCTGACCGCTGCTGAACGCAGTCGTCTGGGTCTGG
AGGCGGGGGAGGGCGTGCGCATCGCCTCGGTCACTGGCGCGGCGGCGCGCAGCACCCAGCCGCCGCTGTCGCCGGGCCTG
ATCATCGCCCGCGTCGGCCGCACCAAGGTCGGTAGCGTCGCCGAGCTCAACCGCGCCCTGTCCAGCTACAAAAAGGGAGA
TGTGGTCATGCTGCTGGTCACCGACGGCAAGGCAACCAGCTACGTGGCCTTGAAGGCCGGCGGCTGA

Upstream 100 bases:

>100_bases
CGGCCTTCATCTGTCGGCCTTCTCCTTTCCCGTTATCGTGCTGGACCCGTGTTGCTACGCGGGTTTGGCCCCTTGTCGCC
CTGCCATCGGAGGCAACCTG

Downstream 100 bases:

>100_bases
GGAAAGCCGGGATTGGTGATTCGGGATTGGCAAGGGCAGGCTCCGCTCGCGGGTGTCTGCCTTTGCGCTGCCGTTTCGAA
TCCCCAATCCCGACTCCCTG

Product: periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDVAPIAANRSATPAPQLVAGLPDFTNLVEQVGPGVVNVETTITRKDAMA
RQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPRQGPGGPGQGDDDGGIAGKSMGSGFIISADGYVLTNHHVVD
GASEVTVKLTDRREFKAKVVGSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSN
PYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAAEQIKATGHVSRGMLGVQ
VGPIDSLKAQGLGLPDSRGALVNDIPAGSPAGKAGVEVGDVIRAVNGKPIDVASDLPPMIGLMAPGSKVTLDVLRDGKPR
KVTVTLAPLQGGSENAAPRTAADEAKPSAPASVELLGLQVADLTAAERSRLGLEAGEGVRIASVTGAAARSTQPPLSPGL
IIARVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG

Sequences:

>Translated_528_residues
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDVAPIAANRSATPAPQLVAGLPDFTNLVEQVGPGVVNVETTITRKDAMA
RQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPRQGPGGPGQGDDDGGIAGKSMGSGFIISADGYVLTNHHVVD
GASEVTVKLTDRREFKAKVVGSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSN
PYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAAEQIKATGHVSRGMLGVQ
VGPIDSLKAQGLGLPDSRGALVNDIPAGSPAGKAGVEVGDVIRAVNGKPIDVASDLPPMIGLMAPGSKVTLDVLRDGKPR
KVTVTLAPLQGGSENAAPRTAADEAKPSAPASVELLGLQVADLTAAERSRLGLEAGEGVRIASVTGAAARSTQPPLSPGL
IIARVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG
>Mature_528_residues
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDVAPIAANRSATPAPQLVAGLPDFTNLVEQVGPGVVNVETTITRKDAMA
RQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPRQGPGGPGQGDDDGGIAGKSMGSGFIISADGYVLTNHHVVD
GASEVTVKLTDRREFKAKVVGSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSN
PYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAFSAAEQIKATGHVSRGMLGVQ
VGPIDSLKAQGLGLPDSRGALVNDIPAGSPAGKAGVEVGDVIRAVNGKPIDVASDLPPMIGLMAPGSKVTLDVLRDGKPR
KVTVTLAPLQGGSENAAPRTAADEAKPSAPASVELLGLQVADLTAAERSRLGLEAGEGVRIASVTGAAARSTQPPLSPGL
IIARVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=254, Percent_Identity=41.3385826771654, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI22129776, Length=255, Percent_Identity=40, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=38.4, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI7019477, Length=255, Percent_Identity=39.2156862745098, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789629, Length=522, Percent_Identity=34.2911877394636, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1786356, Length=500, Percent_Identity=36.6, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1789630, Length=275, Percent_Identity=40.3636363636364, Blast_Score=181, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=39.7923875432526, Blast_Score=169, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 54164; Mature: 54164

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDVAPIAANRSATPAPQLVAGLPDFTNLVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHH
QVGPGVVNVETTITRKDAMARQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPR
HHCCCEEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
QGPGGPGQGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGASEVTVKLTDRREFKAKVV
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEE
GSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSN
CCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHEEECCCCCC
PYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAF
CCCCCCCCCEEEEEEEEECCCCCCCEECCCCCEEEECCEEEECCCCEEEEEEEEEEHHHH
SAAEQIKATGHVSRGMLGVQVGPIDSLKAQGLGLPDSRGALVNDIPAGSPAGKAGVEVGD
HHHHHHHHHCCHHCCEEEEEECCCHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCHHH
VIRAVNGKPIDVASDLPPMIGLMAPGSKVTLDVLRDGKPRKVTVTLAPLQGGSENAAPRT
HHHHCCCCCEECCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCC
AADEAKPSAPASVELLGLQVADLTAAERSRLGLEAGEGVRIASVTGAAARSTQPPLSPGL
CCCCCCCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCCCCCE
IIARVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG
EEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECC
>Mature Secondary Structure
MNHRIRTQMFGLIAMTLPLAACAQQPAPAAKDVAPIAANRSATPAPQLVAGLPDFTNLVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHH
QVGPGVVNVETTITRKDAMARQQRSGPGGRGGGAMPDDDQMPEFFRRFFGPDFQMPGGPR
HHCCCEEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
QGPGGPGQGDDDGGIAGKSMGSGFIISADGYVLTNHHVVDGASEVTVKLTDRREFKAKVV
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCEEECCCCEEEEEEECCCCEEEEEE
GSDEQYDVALLKIEAKGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSATGRSN
CCCCCEEEEEEEEECCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHEEECCCCCC
PYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINSQIFSASGGYMGISFAIPIDLAF
CCCCCCCCCEEEEEEEEECCCCCCCEECCCCCEEEECCEEEECCCCEEEEEEEEEEHHHH
SAAEQIKATGHVSRGMLGVQVGPIDSLKAQGLGLPDSRGALVNDIPAGSPAGKAGVEVGD
HHHHHHHHHCCHHCCEEEEEECCCHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCHHH
VIRAVNGKPIDVASDLPPMIGLMAPGSKVTLDVLRDGKPRKVTVTLAPLQGGSENAAPRT
HHHHCCCCCEECCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCC
AADEAKPSAPASVELLGLQVADLTAAERSRLGLEAGEGVRIASVTGAAARSTQPPLSPGL
CCCCCCCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCEEEEEECCCHHCCCCCCCCCCE
IIARVGRTKVGSVAELNRALSSYKKGDVVMLLVTDGKATSYVALKAGG
EEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]