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The map label for this gene is queC [H]

Identifier: 84623226

GI number: 84623226

Start: 1722885

End: 1723559

Strand: Direct

Name: queC [H]

Synonym: XOO_1569

Alternate gene names: 84623226

Gene position: 1722885-1723559 (Clockwise)

Preceding gene: 84623222

Following gene: 84623240

Centisome position: 34.87

GC content: 66.22

Gene sequence:

>675_bases
ATGAAAAAAGCCGTTGTTCTGTTGTCCGGTGGCATGGATTCCGCCGCTGTCATCGCACTCGCGCAGGAGCAGGGCTTTGC
CGTCTACGCGCTGAGCGTGCGATATGGCCAGCGCCATACCTCGGAACTGGACGCCGCCGCACGCGTTGCCGCCGCACAGG
GCGTCGTTGCGCACAAAGTGGTCGATGTAGACCTGCGCAGCATCGGCGGCTCCGCCCTGACCGACGACATCGACGTCCCC
GACGCCGGTGGTGACGGCATTCCGGTCACGTACGTGCCCGCGCGCAACACCATCATGCTGTCGCTGGCGCTTGGTTGGGC
CGAAGTCGTCGGCGCAAATGACCTGTTCTGCGGCGTCAATGCGGTGGACTACTCGGGCTACCCGGATTGCCGCCCCGAGT
TCGTGCGCGCCTTCGAAGTGCTGGCCAATCTGGCCACCAAGGCAGGCGTGGAAGGCGCGGGGCTGCGCGTGCATGCACCG
CTACAGTTCCTCAGCAAGGCCGACATCGTCCGTGAAGGCGTGCGCCTGGGCGTGGACTTCGGCCTCACCGTCTCCTGCTA
CCGTGCCGACGCTGACGGGCGCGCCTGCGGCCACTGCGATGCATGCCGCTTGCGCGCTGCCGGTTTCGCCGACGCCGGCG
TCCCAGACCCCACCCACTACGCCATTTTATCTTGA

Upstream 100 bases:

>100_bases
TTCACGAGGCCAATATGGACCGATAATCGGTCGCCTGGTCGCCCTGCACCGCGGTCCCTGATAGCCTTCGGCCCTATTCC
GCAGCGATCGCCGATTCGTC

Downstream 100 bases:

>100_bases
CGCTCGCGTAGGGTAGAATGCTCACCCCGACGCAATGTCGGGTCAGTGGGCCGTTAGCTCAGTCGGTAGAGCAGAAGACT
TTTAATCTTTTGGTCGATGG

Product: transcriptional regulator

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKKAVVLLSGGMDSAAVIALAQEQGFAVYALSVRYGQRHTSELDAAARVAAAQGVVAHKVVDVDLRSIGGSALTDDIDVP
DAGGDGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVNAVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAP
LQFLSKADIVREGVRLGVDFGLTVSCYRADADGRACGHCDACRLRAAGFADAGVPDPTHYAILS

Sequences:

>Translated_224_residues
MKKAVVLLSGGMDSAAVIALAQEQGFAVYALSVRYGQRHTSELDAAARVAAAQGVVAHKVVDVDLRSIGGSALTDDIDVP
DAGGDGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVNAVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAP
LQFLSKADIVREGVRLGVDFGLTVSCYRADADGRACGHCDACRLRAAGFADAGVPDPTHYAILS
>Mature_224_residues
MKKAVVLLSGGMDSAAVIALAQEQGFAVYALSVRYGQRHTSELDAAARVAAAQGVVAHKVVDVDLRSIGGSALTDDIDVP
DAGGDGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVNAVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAP
LQFLSKADIVREGVRLGVDFGLTVSCYRADADGRACGHCDACRLRAAGFADAGVPDPTHYAILS

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=225, Percent_Identity=40.8888888888889, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 23264; Mature: 23264

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAVVLLSGGMDSAAVIALAQEQGFAVYALSVRYGQRHTSELDAAARVAAAQGVVAHKV
CCCEEEEEECCCCCEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHEE
VDVDLRSIGGSALTDDIDVPDAGGDGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVN
EEEHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCHHHHHCCCCEEECCE
AVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAPLQFLSKADIVREGVRLGVDF
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCC
GLTVSCYRADADGRACGHCDACRLRAAGFADAGVPDPTHYAILS
CCEEEEEEECCCCCCCCCCHHHHEEECCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MKKAVVLLSGGMDSAAVIALAQEQGFAVYALSVRYGQRHTSELDAAARVAAAQGVVAHKV
CCCEEEEEECCCCCEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHEE
VDVDLRSIGGSALTDDIDVPDAGGDGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVN
EEEHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCHHHHHCCCCEEECCE
AVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAPLQFLSKADIVREGVRLGVDF
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCC
GLTVSCYRADADGRACGHCDACRLRAAGFADAGVPDPTHYAILS
CCEEEEEEECCCCCCCCCCHHHHEEECCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]