Click here to switch to the map view.

The map label for this gene is ispH [H]

Identifier: 84623171

GI number: 84623171

Start: 1658555

End: 1659505

Strand: Direct

Name: ispH [H]

Synonym: XOO_1514

Alternate gene names: 84623171

Gene position: 1658555-1659505 (Clockwise)

Preceding gene: 84623170

Following gene: 84623172

Centisome position: 33.57

GC content: 65.51

Gene sequence:

>951_bases
ATGTACGTCCTGCTCGCCAATCCCCGTGGTTTTTGTGCCGGTGTCGACCGTGCGATCGAGATCGTCAAGCGTGCGATCGA
AACGCTGGGCGCGCCGATCTATGTGCGGCACGAAGTCGTGCACAACCGCTTCGTTGTCGACGACCTCAAACAGCGTGGTG
CGATCTTCGTCGAAGAACTCGACGAAGTGCCCGACGATGCCACGGTGATCTTCAGCGCGCACGGCGTCCCGCAGGCCGTG
CGCCAGGAAGCCGAGCGGCGTGGGCTGAAGGTGTTCGACGCCACCTGCCCGTTGGTGACCAAGGTGCATTTCGAAGTGGC
GCGGCATTGCCGGGCCGGCCGCGACGTGGTGCTGATCGGCCATGCCGGGCACCCGGAAGTGGAAGGCACGATGGGGCAGT
GGAGCCGCGAACGCGGCCCGGGCACGATCTACCTGGTCGAAGACATCGAGCAGGTCGCCACGCTCGATGTCCGCCAGCCC
GAGAATCTCGCTTACACCACCCAGACCACGCTGTCGGTGGACGACACCATGGGCATCATTGAAGCCCTGCGTGCGCGCTA
CCCGGCCATGCAGGGGCCGCGTCACGACGACATCTGCTACGCCACCCAGAACCGCCAGGACGCGGTACGCGATCTGGCCC
GCCAGTGCGATCTGGTGCTGGTGGTCGGTTCGCCGAATAGCTCTAATTCCAACCGGCTGAGCGAGCTGGCCCGGCGCGAT
GGGGTGGAGTCCTACCTGATCGACAACGCCAGCGAGATCGACCCGGCCTGGATCGTCGGCAAGCAGCATATCGGCCTGAC
TGCAGGTGCCTCTGCGCCGCAGGTGCTGGTCGATGGCGTGCTGGCGCGTTTGCGCGAGCTGGGCGCCAGCGGCGTCTCCG
AGCTGGAAGGTGAGCCGGAATCGATGGTATTCGCGCTGCCCAAGGAACTGCGGTTGCGTCTGGTCGGCTGA

Upstream 100 bases:

>100_bases
CAGGCGTCGTGAACCGGGAATCTGCGCTGAAGCCTGCCTGCAGGTGCGTGCGCCCGGTCAGCCCCCCCCCCCTCTGCTCC
ATTCCCGTAGAATGCCCGCT

Downstream 100 bases:

>100_bases
CGCGGCGCCCCCTAGTCCGGCCGCGGCGCTTGCCGCGATTGACCCGGGGCGGCTGCGCTCCTACAATTCACGGCTCGCCG
GAATAGCTCAGTTGGTAGAG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVPQAV
RQEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGPGTIYLVEDIEQVATLDVRQP
ENLAYTTQTTLSVDDTMGIIEALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRD
GVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGASGVSELEGEPESMVFALPKELRLRLVG

Sequences:

>Translated_316_residues
MYVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVPQAV
RQEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGPGTIYLVEDIEQVATLDVRQP
ENLAYTTQTTLSVDDTMGIIEALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRD
GVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGASGVSELEGEPESMVFALPKELRLRLVG
>Mature_316_residues
MYVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVPQAV
RQEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGPGTIYLVEDIEQVATLDVRQP
ENLAYTTQTTLSVDDTMGIIEALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRD
GVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGASGVSELEGEPESMVFALPKELRLRLVG

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=312, Percent_Identity=63.1410256410256, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34717; Mature: 34717

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEEL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCEEHHHH
DEVPDDATVIFSAHGVPQAVRQEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIG
HCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEE
HAGHPEVEGTMGQWSRERGPGTIYLVEDIEQVATLDVRQPENLAYTTQTTLSVDDTMGII
CCCCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHH
EALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRD
HHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHC
GVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGASGVSELEGEPE
CCHHHHHCCCCCCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCC
SMVFALPKELRLRLVG
CEEEECCHHHEEEECC
>Mature Secondary Structure
MYVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEEL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCEEHHHH
DEVPDDATVIFSAHGVPQAVRQEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIG
HCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEE
HAGHPEVEGTMGQWSRERGPGTIYLVEDIEQVATLDVRQPENLAYTTQTTLSVDDTMGII
CCCCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHH
EALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRD
HHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHC
GVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGASGVSELEGEPE
CCHHHHHCCCCCCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCC
SMVFALPKELRLRLVG
CEEEECCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA