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The map label for this gene is obgE [H]

Identifier: 84623165

GI number: 84623165

Start: 1650464

End: 1651516

Strand: Direct

Name: obgE [H]

Synonym: XOO_1508

Alternate gene names: 84623165

Gene position: 1650464-1651516 (Clockwise)

Preceding gene: 84623164

Following gene: 84623167

Centisome position: 33.41

GC content: 64.96

Gene sequence:

>1053_bases
ATGAAGTTAGTCGACGAAGCAGAAATCCTGGTCACCGCAGGTCATGGCGGCAATGGCTGTGTCGGCTTTCGCCGCGAGAA
GTTCATCCCGCTGGGCGGGCCCGATGGCGGCGACGGCGGTAGTGGCGGCAGCGTGTGGATCGTGGCCGACGAGAACGTCA
ACACCCTGGTCGATTTCCGCCATGAGCGCACCTTCAAGGCGCAGCGTGGCGAGAACGGCATGGGCCGTCAGGCCTACGGC
AAGGGCGGCGAAGACCGCATCATCGTGGTGCCGGTCGGTACCGTGGTGATCAATGTGCAGACCGACGAAGTCATCGGCGA
CCTGACCCGGCACGGCGACCGCTTGCTGGTGGCCAAGGGCGGCAAGGGCGGCCTGGGCAACATGCATTTCAAGAGCTCAG
TCAACCGTGCGCCGCGCCAATCCACCACCGGCGAAGAGGGTGAGGAGCGGCTGCTGAAGCTGGAACTCAGGCTGCTTGCG
GATGTGGGTCTGCTGGGCTTCCCGAACGCCGGCAAGAGCACGCTGATCCGCGCGGTGTCCTCCGCAACGCCGAAGGTGGC
CGACTACCCGTTCACCACGCTGTATCCCAATCTGGGCGTGGTCAGTGTCGAGGCATACCGTAGCTTCGTCATCGCCGACG
TGCCGGGCCTGATCGAAGGTGCTGCCGACGGCGCTGGGCTGGGGACGCAGTTCCTGCGCCATCTGCAGCGCACCCGTTTG
CTGCTGCATCTGGTGGATATGGCCCCGATGGATGGTGGCGTGGACGGTGTATCGCCGGCCGACCAGGTGCGCACCCTCGA
GCGCGAGCTGGAGCGCCACGATCCCCAACTGCTGAAGAAGCCGCGCTGGCTGGTGCTCAACAAGGCCGACCTGATGTTCG
AAGACGAGGCGCGTGCCGCTGCCGAAACCATCGTCGCCGAGCTGGGTTGGACTGCGCCGTGGTACCTGGTATCTGCCCTT
GGGCGCGATGGTACGTTCCCGATCATGAAAGACGTCATGGCGTTCTTCGACCGCCAGCGCGAAGACGAGCTTGAAGCGCG
CAATGCGGGCTGA

Upstream 100 bases:

>100_bases
GTCCTGTACGTTCCGATGCCGTTGCTTCCTGCTTTCCCGCGGCCGCCAAGTGGCGTCCTGCGGTGGTGTTACCAATCCTA
AATGACGAATTCCAAATCTC

Downstream 100 bases:

>100_bases
GCGCAGGCGCAGGCACAAAAAAAACCCGGCCGAGGCCGGGTTTTTCTGTATTGCCGGCAGCCAGGCTCCCGGCAATGCGC
CAACTGATCGCTTACGCGGC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKLVDEAEILVTAGHGGNGCVGFRREKFIPLGGPDGGDGGSGGSVWIVADENVNTLVDFRHERTFKAQRGENGMGRQAYG
KGGEDRIIVVPVGTVVINVQTDEVIGDLTRHGDRLLVAKGGKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELRLLA
DVGLLGFPNAGKSTLIRAVSSATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRL
LLHLVDMAPMDGGVDGVSPADQVRTLERELERHDPQLLKKPRWLVLNKADLMFEDEARAAAETIVAELGWTAPWYLVSAL
GRDGTFPIMKDVMAFFDRQREDELEARNAG

Sequences:

>Translated_350_residues
MKLVDEAEILVTAGHGGNGCVGFRREKFIPLGGPDGGDGGSGGSVWIVADENVNTLVDFRHERTFKAQRGENGMGRQAYG
KGGEDRIIVVPVGTVVINVQTDEVIGDLTRHGDRLLVAKGGKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELRLLA
DVGLLGFPNAGKSTLIRAVSSATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRL
LLHLVDMAPMDGGVDGVSPADQVRTLERELERHDPQLLKKPRWLVLNKADLMFEDEARAAAETIVAELGWTAPWYLVSAL
GRDGTFPIMKDVMAFFDRQREDELEARNAG
>Mature_350_residues
MKLVDEAEILVTAGHGGNGCVGFRREKFIPLGGPDGGDGGSGGSVWIVADENVNTLVDFRHERTFKAQRGENGMGRQAYG
KGGEDRIIVVPVGTVVINVQTDEVIGDLTRHGDRLLVAKGGKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELRLLA
DVGLLGFPNAGKSTLIRAVSSATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRL
LLHLVDMAPMDGGVDGVSPADQVRTLERELERHDPQLLKKPRWLVLNKADLMFEDEARAAAETIVAELGWTAPWYLVSAL
GRDGTFPIMKDVMAFFDRQREDELEARNAG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=342, Percent_Identity=39.766081871345, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI111955139, Length=276, Percent_Identity=39.8550724637681, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI111955063, Length=138, Percent_Identity=42.7536231884058, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI4557537, Length=130, Percent_Identity=33.8461538461538, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=60.7142857142857, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1787454, Length=147, Percent_Identity=31.9727891156463, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=337, Percent_Identity=37.9821958456973, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=30.1948051948052, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=154, Percent_Identity=30.5194805194805, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=122, Percent_Identity=37.7049180327869, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=122, Percent_Identity=35.2459016393443, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=193, Percent_Identity=35.7512953367876, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=132, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585318, Length=314, Percent_Identity=38.2165605095541, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI20129375, Length=288, Percent_Identity=40.625, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI17981711, Length=131, Percent_Identity=35.8778625954198, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640873, Length=141, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640877, Length=141, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640875, Length=141, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356473, Length=112, Percent_Identity=35.7142857142857, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37867; Mature: 37867

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVDEAEILVTAGHGGNGCVGFRREKFIPLGGPDGGDGGSGGSVWIVADENVNTLVDFR
CCCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHH
HERTFKAQRGENGMGRQAYGKGGEDRIIVVPVGTVVINVQTDEVIGDLTRHGDRLLVAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECEEEEEEEHHHHHHHHHHCCCEEEEEEC
GKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELRLLADVGLLGFPNAGKSTLIRAVS
CCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
SATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRL
HCCCCCCCCCCHHHCCCCCEEEHHHHHHHHEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHLVDMAPMDGGVDGVSPADQVRTLERELERHDPQLLKKPRWLVLNKADLMFEDEARAA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCEECCHHHHH
AETIVAELGWTAPWYLVSALGRDGTFPIMKDVMAFFDRQREDELEARNAG
HHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MKLVDEAEILVTAGHGGNGCVGFRREKFIPLGGPDGGDGGSGGSVWIVADENVNTLVDFR
CCCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHH
HERTFKAQRGENGMGRQAYGKGGEDRIIVVPVGTVVINVQTDEVIGDLTRHGDRLLVAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECEEEEEEEHHHHHHHHHHCCCEEEEEEC
GKGGLGNMHFKSSVNRAPRQSTTGEEGEERLLKLELRLLADVGLLGFPNAGKSTLIRAVS
CCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
SATPKVADYPFTTLYPNLGVVSVEAYRSFVIADVPGLIEGAADGAGLGTQFLRHLQRTRL
HCCCCCCCCCCHHHCCCCCEEEHHHHHHHHEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHLVDMAPMDGGVDGVSPADQVRTLERELERHDPQLLKKPRWLVLNKADLMFEDEARAA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCEECCHHHHH
AETIVAELGWTAPWYLVSALGRDGTFPIMKDVMAFFDRQREDELEARNAG
HHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]