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The map label for this gene is cobT [H]

Identifier: 84622898

GI number: 84622898

Start: 1351464

End: 1352510

Strand: Direct

Name: cobT [H]

Synonym: XOO_1241

Alternate gene names: 84622898

Gene position: 1351464-1352510 (Clockwise)

Preceding gene: 84622897

Following gene: 84622899

Centisome position: 27.36

GC content: 67.72

Gene sequence:

>1047_bases
GTGAGTAACGATTGGATCTTTGGTGCCTGCGCCGTGCCGGACGCGCGCATGCGCTCTGCTGCGTTGGCCCGGCAGGAACA
ACTGACCAAACCGCCGGGCGCATTGGGCCGGCTGGAACAACTGGCCGTGCAACTGGCGGCCTGGCAACGTACCGAACATC
CTGCGGTGCAGCGGGTCTGGATTGCGGTGTATGCCGCCGATCATGGTGTGGCGGCCGAAGGCGTGTCGGCATTTCCGCAG
GCAGTCACCGGCGAGATGGTGCGCAATTTCGCGCGCGGCGGTGCGGCTATTGCGGTCCTGGCGCGCGAGCTGGGTGCGCG
GCTGGAAGTGGTGAATCTGGGGGTTGTCAACGACCCCGGTGACTTGTCGCGCGTGCGGCGTGCCTGGATTGCGCCGTCCA
CCGCCAATATCTGCGAGCAGCCCGCGATGACGGCCACGCAACTGCGCGATGCGCTCGCCGCTGGTGCCCACAGCATTGCG
CAGGCCAAGGGTTGCGACACGCAGCTGTTTGTCGGCGGCGAAATGGGCATTGGCAACACCACCGCCGCTGCAGCGCTGGG
CTGCGCGTTGCTCTCGCAGTTTCCGCAGGCGCTGGCTGGCGCAGGCACCGGCCTGGATGCCGAAGGCATCGCGCACAAGG
TCACCGTGATCACGCGTGCGCTGGCCTTACATGCCGATGCCTCCACCCCGCTGGAGCGTCTGCGCCGGCTCGGCGGATTC
GAAATCGCGGCATTGGTCGGCGCGTATATCGCTGCGGCGCAGGCGGGCATTCCGGTGTTGGTGGATGGCTTCATCGCCAC
CGCCGCGGCATTGGTGGCCAGCCGCCTGAACCCCGGCGTGCGCGAGTGGTTGTTGTTCGGGCACCGTTCGCAGGAGCGCG
GGCATGCGGCACTGCTGCGTGCGCTGGATGCAGAGCCCTTGCTGCAACTGGACCTGCGGCTGGGAGAAGCCAGCGGCGCC
GCGGTGGCGATTCCGTTGCTGCGCAGCGCCTGCGCGTTGCATAACGGCATGGCGACCTTCGCCGAAGCCGGAGTGTCGGA
CGCATGA

Upstream 100 bases:

>100_bases
TCAACGAAGCCGGCTGGCTGCATCAGGCATTGGCGCTACAGTGCGAGCGCGTGGTGTTTGTGGTGGCAGGATTACCGATG
GTGTTGAAGGGAGAGTACAT

Downstream 100 bases:

>100_bases
GAGCACAGATCACCTTGTTGCGGCATGGCGACACCGGGCAACGCAGCTATCGCGGTCAGCTCGACGATCCACTTACCGAG
CTGGGCTGGCAGCAATTACG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSNDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEQLAVQLAAWQRTEHPAVQRVWIAVYAADHGVAAEGVSAFPQ
AVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLSRVRRAWIAPSTANICEQPAMTATQLRDALAAGAHSIA
QAKGCDTQLFVGGEMGIGNTTAAAALGCALLSQFPQALAGAGTGLDAEGIAHKVTVITRALALHADASTPLERLRRLGGF
EIAALVGAYIAAAQAGIPVLVDGFIATAAALVASRLNPGVREWLLFGHRSQERGHAALLRALDAEPLLQLDLRLGEASGA
AVAIPLLRSACALHNGMATFAEAGVSDA

Sequences:

>Translated_348_residues
MSNDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEQLAVQLAAWQRTEHPAVQRVWIAVYAADHGVAAEGVSAFPQ
AVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLSRVRRAWIAPSTANICEQPAMTATQLRDALAAGAHSIA
QAKGCDTQLFVGGEMGIGNTTAAAALGCALLSQFPQALAGAGTGLDAEGIAHKVTVITRALALHADASTPLERLRRLGGF
EIAALVGAYIAAAQAGIPVLVDGFIATAAALVASRLNPGVREWLLFGHRSQERGHAALLRALDAEPLLQLDLRLGEASGA
AVAIPLLRSACALHNGMATFAEAGVSDA
>Mature_347_residues
SNDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEQLAVQLAAWQRTEHPAVQRVWIAVYAADHGVAAEGVSAFPQA
VTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLSRVRRAWIAPSTANICEQPAMTATQLRDALAAGAHSIAQ
AKGCDTQLFVGGEMGIGNTTAAAALGCALLSQFPQALAGAGTGLDAEGIAHKVTVITRALALHADASTPLERLRRLGGFE
IAALVGAYIAAAQAGIPVLVDGFIATAAALVASRLNPGVREWLLFGHRSQERGHAALLRALDAEPLLQLDLRLGEASGAA
VAIPLLRSACALHNGMATFAEAGVSDA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=335, Percent_Identity=34.3283582089552, Blast_Score=191, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35925; Mature: 35793

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEQLAVQLAAWQRTEHPAVQRVW
CCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
IAVYAADHGVAAEGVSAFPQAVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPG
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEEEECCCCH
DLSRVRRAWIAPSTANICEQPAMTATQLRDALAAGAHSIAQAKGCDTQLFVGGEMGIGNT
HHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCH
TAAAALGCALLSQFPQALAGAGTGLDAEGIAHKVTVITRALALHADASTPLERLRRLGGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCH
EIAALVGAYIAAAQAGIPVLVDGFIATAAALVASRLNPGVREWLLFGHRSQERGHAALLR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
ALDAEPLLQLDLRLGEASGAAVAIPLLRSACALHNGMATFAEAGVSDA
HHCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHCCCCCC
>Mature Secondary Structure 
SNDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEQLAVQLAAWQRTEHPAVQRVW
CCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
IAVYAADHGVAAEGVSAFPQAVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPG
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEEEECCCCH
DLSRVRRAWIAPSTANICEQPAMTATQLRDALAAGAHSIAQAKGCDTQLFVGGEMGIGNT
HHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCH
TAAAALGCALLSQFPQALAGAGTGLDAEGIAHKVTVITRALALHADASTPLERLRRLGGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCH
EIAALVGAYIAAAQAGIPVLVDGFIATAAALVASRLNPGVREWLLFGHRSQERGHAALLR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
ALDAEPLLQLDLRLGEASGAAVAIPLLRSACALHNGMATFAEAGVSDA
HHCCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]