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The map label for this gene is cobU [H]

Identifier: 84622897

GI number: 84622897

Start: 1350946

End: 1351467

Strand: Direct

Name: cobU [H]

Synonym: XOO_1240

Alternate gene names: 84622897

Gene position: 1350946-1351467 (Clockwise)

Preceding gene: 84622896

Following gene: 84622898

Centisome position: 27.35

GC content: 64.37

Gene sequence:

>522_bases
ATGCAGCACCTGATTCTGGGCGGCGCCCGTTCGGGCAAGAGCGCTCTGGCCGAGCGCATCGCGCTAACCTCCGGGCTTGC
AGTGACGTATCTCGCCACCGCGCAAGCCTTCGACGATGAAATGCAGCGGCGCATTGCCCATCACCGCAGCCAACGCTCGC
CGCAGTGGCAATGCGTGGAAGAGCCCATCGCGCTGGCGGCGACGTTGCAGGCGCATGCTGCGCCGGATTGCTGCGTGCTG
GTGGATTGCCTCACCCTGTGGCTGAGCAATCTACTCGGCCACCCGGATGCAGGCGTGTTCGCGCGCGAGCGCGACGCGCT
GCTGGCAACGCTGCCGCAGTTGCCGGGGCAGATTGTGCTGGTCAGCAACGAAGTGGGACAGGGCATCGTGCCGCTGGGCG
AACTCACGCGTCGTTTTGTCAACGAAGCCGGCTGGCTGCATCAGGCATTGGCGCTACAGTGCGAGCGCGTGGTGTTTGTG
GTGGCAGGATTACCGATGGTGTTGAAGGGAGAGTACATGTGA

Upstream 100 bases:

>100_bases
TGCCGCGTTGCGTGAAGCCAGCCTCGATCGTCTGGCCGATGCTCGTGCATACGCATCTGGACACCACCGCACTGACACCA
CTCATCAGCAGGGAACCGGC

Downstream 100 bases:

>100_bases
GTAACGATTGGATCTTTGGTGCCTGCGCCGTGCCGGACGCGCGCATGCGCTCTGCTGCGTTGGCCCGGCAGGAACAACTG
ACCAAACCGCCGGGCGCATT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MQHLILGGARSGKSALAERIALTSGLAVTYLATAQAFDDEMQRRIAHHRSQRSPQWQCVEEPIALAATLQAHAAPDCCVL
VDCLTLWLSNLLGHPDAGVFARERDALLATLPQLPGQIVLVSNEVGQGIVPLGELTRRFVNEAGWLHQALALQCERVVFV
VAGLPMVLKGEYM

Sequences:

>Translated_173_residues
MQHLILGGARSGKSALAERIALTSGLAVTYLATAQAFDDEMQRRIAHHRSQRSPQWQCVEEPIALAATLQAHAAPDCCVL
VDCLTLWLSNLLGHPDAGVFARERDALLATLPQLPGQIVLVSNEVGQGIVPLGELTRRFVNEAGWLHQALALQCERVVFV
VAGLPMVLKGEYM
>Mature_173_residues
MQHLILGGARSGKSALAERIALTSGLAVTYLATAQAFDDEMQRRIAHHRSQRSPQWQCVEEPIALAATLQAHAAPDCCVL
VDCLTLWLSNLLGHPDAGVFARERDALLATLPQLPGQIVLVSNEVGQGIVPLGELTRRFVNEAGWLHQALALQCERVVFV
VAGLPMVLKGEYM

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=39.010989010989, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18770; Mature: 18770

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLILGGARSGKSALAERIALTSGLAVTYLATAQAFDDEMQRRIAHHRSQRSPQWQCVE
CCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EPIALAATLQAHAAPDCCVLVDCLTLWLSNLLGHPDAGVFARERDALLATLPQLPGQIVL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEE
VSNEVGQGIVPLGELTRRFVNEAGWLHQALALQCERVVFVVAGLPMVLKGEYM
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC
>Mature Secondary Structure
MQHLILGGARSGKSALAERIALTSGLAVTYLATAQAFDDEMQRRIAHHRSQRSPQWQCVE
CCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EPIALAATLQAHAAPDCCVLVDCLTLWLSNLLGHPDAGVFARERDALLATLPQLPGQIVL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEE
VSNEVGQGIVPLGELTRRFVNEAGWLHQALALQCERVVFVVAGLPMVLKGEYM
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]