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The map label for this gene is argD [H]

Identifier: 84622772

GI number: 84622772

Start: 1210256

End: 1211482

Strand: Direct

Name: argD [H]

Synonym: XOO_1115

Alternate gene names: 84622772

Gene position: 1210256-1211482 (Clockwise)

Preceding gene: 84622770

Following gene: 84622775

Centisome position: 24.5

GC content: 66.83

Gene sequence:

>1227_bases
ATGAGCACCGCTGCCGATTCGCCCCTGTCCCTCGCGCACTACTACCTGCCGGTGTATCGCCCGCGCCAGGTGGTGCTGGA
GCGTGGCCAGGGCAGCCGCGTGTGGGACGACCAGGGACGTGAGTATCTGGATCTGTCGTCGGGCATCGCGGTCAGCGGGC
TCGGCCATAACGATCCTGATCTGATGGCTGCGCTTACCGAGCAGGCCGCCAAGCTGTGGCATACCAGTAACGTGTTCTTC
AGCGCGCCGCCGCTGAAACTGGCCGAAGAACTGGTGACCGCCTCGCGTTTCGCGCTCAAGGTGTTCCTGTGCAATTCCGG
CACCGAGGCCAATGAGGCGGCGATCAAGCTGGTGCGCAAGTGGGCCAGTAGCCACGGCCGGCCGGCCGACAAGCGCGTCA
TTGTCACGTTTGGCGGCAGTTTCCATGGCCGCACGCTGGCGTCGGTGACCGCAACCGCCCAGCCCAAGTATCAGGAAGGC
TACGAGCCATTGCCGGGCGGTTTTCGCCATGTGGATTTCAACGACGTTACGGCGCTGGAAGCGGCGATGGCCAGCGGCGA
TGTAGCCGCGGTGATGGTTGAGCCGATTCAGGGCGAGGGCGGGGTAATGCCGGCCGCGCCGGGCTTCTTGAGCCGGGTAC
GCGCGCTCTGCGATCAGCACGATGCGCTGCTGGTGCTGGACGAAATTCAATGCGGTATGGGCCGTACCGGCACGCTGTTC
GCGCACTGGCAGGACCAGGTGACGCCGGACATCGTGACCCTGGCCAAGGCCCTGGGTGGTGGTTTTCCGATCGGCGCGAT
GCTGGCTGGGCCCAAGGTGGCCGAAACCATGCAGTTCGGCGCGCACGGCACCACCTTCGGCGGCAACCCGCTGGCCGCGG
CAGTGGCGCGCGTGGCGCTGCGCAAGCTGGCCTCGCCGCAGATTGCCGACAACGTGGCGCGGCAGTCGGCGGCGTTGCGC
GCGGGCCTGGAAGCGCTCAATGCCGACTTCGATCTGTTTGCGCAGATTCGCGGACGTGGCTTGATGCTGGGTGCGGTACT
GGCGCCGGCGCACGCGGGTCAGGCCGGGGCGATCCTCGACCTGGCGGCCAAGCATGGCTTGCTGCTGCTGCAGGCTGGCC
CGGACGTACTGCGCTTTGTGCCGGCACTCAACCTGACCGATGCCGAGCTGGCGGATGGCCTGGCGTGTTTGCGTCTGGCG
CTTGCCGAGTACGTTGCGCAGTCGTGA

Upstream 100 bases:

>100_bases
TGAGTTGCGGATCTGAGAAAGGGCGCATGCGCGCATTGTGCCGCAGGCCGGCGAATGCGCGAGAATGCGGGTTCTCCCTC
CGCTTTAGCGACCCATCCTC

Downstream 100 bases:

>100_bases
TGATGGGAGCTGCCTGCGCGTCTTGTAGCCGGCGCTAAGCCGGTTAGCAGAGTGTTGGAGATGCGTGGTGTGTGGCGTGC
ATCTCACGCAATGTGCGTGG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDQGREYLDLSSGIAVSGLGHNDPDLMAALTEQAAKLWHTSNVFF
SAPPLKLAEELVTASRFALKVFLCNSGTEANEAAIKLVRKWASSHGRPADKRVIVTFGGSFHGRTLASVTATAQPKYQEG
YEPLPGGFRHVDFNDVTALEAAMASGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
AHWQDQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVARQSAALR
AGLEALNADFDLFAQIRGRGLMLGAVLAPAHAGQAGAILDLAAKHGLLLLQAGPDVLRFVPALNLTDAELADGLACLRLA
LAEYVAQS

Sequences:

>Translated_408_residues
MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDQGREYLDLSSGIAVSGLGHNDPDLMAALTEQAAKLWHTSNVFF
SAPPLKLAEELVTASRFALKVFLCNSGTEANEAAIKLVRKWASSHGRPADKRVIVTFGGSFHGRTLASVTATAQPKYQEG
YEPLPGGFRHVDFNDVTALEAAMASGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
AHWQDQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVARQSAALR
AGLEALNADFDLFAQIRGRGLMLGAVLAPAHAGQAGAILDLAAKHGLLLLQAGPDVLRFVPALNLTDAELADGLACLRLA
LAEYVAQS
>Mature_407_residues
STAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDQGREYLDLSSGIAVSGLGHNDPDLMAALTEQAAKLWHTSNVFFS
APPLKLAEELVTASRFALKVFLCNSGTEANEAAIKLVRKWASSHGRPADKRVIVTFGGSFHGRTLASVTATAQPKYQEGY
EPLPGGFRHVDFNDVTALEAAMASGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLFA
HWQDQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVALRKLASPQIADNVARQSAALRA
GLEALNADFDLFAQIRGRGLMLGAVLAPAHAGQAGAILDLAAKHGLLLLQAGPDVLRFVPALNLTDAELADGLACLRLAL
AEYVAQS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=37.8865979381443, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=38.0794701986755, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI13994255, Length=450, Percent_Identity=28.4444444444444, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=27.2727272727273, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI226442705, Length=407, Percent_Identity=27.027027027027, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=27.0053475935829, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI24119277, Length=400, Percent_Identity=28, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI188536080, Length=416, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38679950, Length=416, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38679946, Length=416, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788044, Length=395, Percent_Identity=48.1012658227848, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=48.2051282051282, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI145693181, Length=325, Percent_Identity=39.3846153846154, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=33.4975369458128, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=30.6930693069307, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786991, Length=397, Percent_Identity=31.2342569269521, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1786349, Length=313, Percent_Identity=30.0319488817891, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=392, Percent_Identity=35.969387755102, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=28.9293849658314, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=281, Percent_Identity=35.5871886120996, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=25.5220417633411, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=427, Percent_Identity=26.9320843091335, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=34.5911949685535, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=38.7909319899244, Blast_Score=283, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=398, Percent_Identity=32.9145728643216, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=359, Percent_Identity=29.2479108635098, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=362, Percent_Identity=25.1381215469613, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357415, Length=382, Percent_Identity=37.696335078534, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI28574759, Length=454, Percent_Identity=29.9559471365639, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161085790, Length=454, Percent_Identity=29.7356828193833, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21356575, Length=405, Percent_Identity=27.1604938271605, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281366494, Length=409, Percent_Identity=25.9168704156479, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24667139, Length=409, Percent_Identity=25.9168704156479, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24667143, Length=409, Percent_Identity=25.9168704156479, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42904; Mature: 42772

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDQGREYLDLSSGIAVSGLGHNDPD
CCCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCCHHCCCEEEECCCCCEEECCCCCCHH
LMAALTEQAAKLWHTSNVFFSAPPLKLAEELVTASRFALKVFLCNSGTEANEAAIKLVRK
HHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHH
WASSHGRPADKRVIVTFGGSFHGRTLASVTATAQPKYQEGYEPLPGGFRHVDFNDVTALE
HHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHCCCCCCCCCCEECCCCHHHHHH
AAMASGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
HHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHCCCCCCCEEE
AHWQDQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVAL
EECCCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RKLASPQIADNVARQSAALRAGLEALNADFDLFAQIRGRGLMLGAVLAPAHAGQAGAILD
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEHHHCCCCCCCCCHHHH
LAAKHGLLLLQAGPDVLRFVPALNLTDAELADGLACLRLALAEYVAQS
HHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STAADSPLSLAHYYLPVYRPRQVVLERGQGSRVWDDQGREYLDLSSGIAVSGLGHNDPD
CCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCCHHCCCEEEECCCCCEEECCCCCCHH
LMAALTEQAAKLWHTSNVFFSAPPLKLAEELVTASRFALKVFLCNSGTEANEAAIKLVRK
HHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHH
WASSHGRPADKRVIVTFGGSFHGRTLASVTATAQPKYQEGYEPLPGGFRHVDFNDVTALE
HHHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHCCCCCCCCCCEECCCCHHHHHH
AAMASGDVAAVMVEPIQGEGGVMPAAPGFLSRVRALCDQHDALLVLDEIQCGMGRTGTLF
HHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHCCCCCCCEEE
AHWQDQVTPDIVTLAKALGGGFPIGAMLAGPKVAETMQFGAHGTTFGGNPLAAAVARVAL
EECCCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RKLASPQIADNVARQSAALRAGLEALNADFDLFAQIRGRGLMLGAVLAPAHAGQAGAILD
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEHHHCCCCCCCCCHHHH
LAAKHGLLLLQAGPDVLRFVPALNLTDAELADGLACLRLALAEYVAQS
HHHHCCEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]