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The map label for this gene is nagJ [H]

Identifier: 84621846

GI number: 84621846

Start: 199430

End: 201415

Strand: Direct

Name: nagJ [H]

Synonym: XOO_0189

Alternate gene names: 84621846

Gene position: 199430-201415 (Clockwise)

Preceding gene: 84621845

Following gene: 84621848

Centisome position: 4.04

GC content: 65.91

Gene sequence:

>1986_bases
ATGACGCGACGCAACAGCAAGCCGGGCGTGCGCCTGCTTTCGGTATTGGTGGCGCTGGGCATGGCTGCCCCGGCGTTGGC
GCAGGCGGTGACCGAACCGGTCACCCAGCCCGCGATCTATCCGACGCCGGTATCGATCACGCTGGACGGCGCGACCATCG
CGCTGGGCCGCTCGGTGGTGCTGGTGGTCGCGCCGGGCGCGGACAAGGCCACAGTCGCGCTGGTGCGCAGCATTCTCAGC
AGCGCCGGGGTCACCAAAATGGCGACCGCCACGCGCTTGCCTGCCACGCTGGACCGCCCGCACATCGTGCTCGGCACCGG
CGATGCGGCAGTGGTGCGCGATGCGCTGGCGCGTAGCAAGGCGAGGCAGGATACCCACAAGGAGGGCTATACGCTGGCCA
GCGTTGCGCTCGATGGCGGCAGCCTGATCACGCTGGCCGGCCACGACGACGATGGCCTGTTCCATGCGGCGCAGACGCTG
CGGCAGCTGGTCGAGCGGCCGGCCATCCCGACGCTGACGATCCATGATTACCCGGCCATGCCGATCCGCGGCACCATCGA
AGGCTTCTACGGCGCGCCGTGGTCGATGAGCGATCGCAGCAAGCACATCGATTTCCTTGCCCGCACCAAGGCCAACACCT
TCATCTATAGCCCGAAAGACGACCCTTACGCGCGCGATCGCTGGCGCGCGCCGTACCCGAAGGCGACCTTGAAAGCACTC
GGCCAGCTGGCCGCTACCGCCAAGCGCAATCACGTCGATTTCGTCTATGCGATTTCGCCGGGACCGACGGTCTGTTTCTC
CGACCCGGCCGATGCCAAGGCGTTGCTGCGCAAGTTTGATGCGTTCCGCGCGCTGGGTGTGCGCAGCTTCTATGTGGCGC
TGGACGATATCGAATACACCAAGTGGAATTGCGAGCGCGACAAGACCGCCTTCGGCGAGTCCGGTGCGCAGGCAGCAGGT
ATCGCGCAGTCGCACCTGCTCAACCTGGTGCAAGCCGATCTGGTTGCGCGCCACGATGCAACCTCGGAACTGATCATGGT
GCCCACCGAGTACTACGACGCCAAAGAGAGCCCGTACAAGGAAGCGCTGCGCAAGCACCTGGACCCGAAGATCGTGGTGC
AGTGGACCGGTACCGACGTGGTGCCGCCGGCCATTTCCATCCCCGATGCGCGTGCGGCCACCAAGGCGTTCGGTCGTAAG
ACGCTGCTATGGGACAACTACCCGGTCAACGATTTCGAAACCTCGGCCGGGCGCTTGCTGATGGCGCCGTATGCACGGCG
CGAGGCCGGCCTGTCGGCCGAGTTGTCCGGCATCGTGTCCAATCCGATGAATCAGGAAGTACCCAGCCGCGTCGCAGTGA
TGGGGCTGACCGCGTTCGCCTGGAACGACAAAGACTACGACGCGCAACGCACCTGGCATGCGGCAGCGCGCGATCTGGCC
GGCGGCGATGCGCGTGTCACTGCGGCATTGCTGATCTTCTTCGATACCCAGCACTTGGCGCCAACCTTCGGCAGCCAACC
GTGGCAGGAACAGGCGCCACGCTTGAAGGCCGTGCTTGATCATGTGCGCGAGGCGATCGCGCTTGGCGATGCCGCAGCGC
GCACCCAGGCGATTGCCGAACTGGCACGCACTGCAGACGAAATGGCTGCCGCGCCGCAGATCATTCGCGATAGCGTCGCC
GACAAGGGTTTTGCCAAGCAATCGCGCCCGTGGCTGGAGGCAATGGAAGTCTGGGGCGGCGCGTTGCAGAAGACGGCAGC
CGGGCTGGATGCGGCAAATCGCGGCGACACGCAGGCGCCCGCGTTGTTTGCCGAGGCGGCTGCACACGCCGCTGTCGCTG
CTGTGGTTCCGTCGATTCCCGGCGCCACGCGCTTCGATGGCCCGGTCAAGATCGCCGACGGCGTACTCGACCGCTTCATC
GCGCAGGCGCCGCGCTTGATCGCTTATCGCGTGCCGGCAGTTGCCGATTCGGCAGCAGCGAAGTGA

Upstream 100 bases:

>100_bases
AGAAAACAACCCGTCCCGGACACAGGTACGGCGCCGCTTGTCGCCGCCCCGCGACTTGCCTACTCTAGGGCGTAATACCA
TTCCAATACCGGAGTTCGAG

Downstream 100 bases:

>100_bases
TGGCTTAGTGCAGAGGCACAGCTGCGCGCATGGGCGACTGTTCGCGTATTTAGAGCGGCGAACAAACCGCAGCGAGCCGC
TGTCAGGTGGGCGCGGACGG

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; Beta-hexosaminidase; GH84; Hexosaminidase B; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MTRRNSKPGVRLLSVLVALGMAAPALAQAVTEPVTQPAIYPTPVSITLDGATIALGRSVVLVVAPGADKATVALVRSILS
SAGVTKMATATRLPATLDRPHIVLGTGDAAVVRDALARSKARQDTHKEGYTLASVALDGGSLITLAGHDDDGLFHAAQTL
RQLVERPAIPTLTIHDYPAMPIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWRAPYPKATLKAL
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYTKWNCERDKTAFGESGAQAAG
IAQSHLLNLVQADLVARHDATSELIMVPTEYYDAKESPYKEALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRK
TLLWDNYPVNDFETSAGRLLMAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGLTAFAWNDKDYDAQRTWHAAARDLA
GGDARVTAALLIFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAIALGDAAARTQAIAELARTADEMAAAPQIIRDSVA
DKGFAKQSRPWLEAMEVWGGALQKTAAGLDAANRGDTQAPALFAEAAAHAAVAAVVPSIPGATRFDGPVKIADGVLDRFI
AQAPRLIAYRVPAVADSAAAK

Sequences:

>Translated_661_residues
MTRRNSKPGVRLLSVLVALGMAAPALAQAVTEPVTQPAIYPTPVSITLDGATIALGRSVVLVVAPGADKATVALVRSILS
SAGVTKMATATRLPATLDRPHIVLGTGDAAVVRDALARSKARQDTHKEGYTLASVALDGGSLITLAGHDDDGLFHAAQTL
RQLVERPAIPTLTIHDYPAMPIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWRAPYPKATLKAL
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYTKWNCERDKTAFGESGAQAAG
IAQSHLLNLVQADLVARHDATSELIMVPTEYYDAKESPYKEALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRK
TLLWDNYPVNDFETSAGRLLMAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGLTAFAWNDKDYDAQRTWHAAARDLA
GGDARVTAALLIFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAIALGDAAARTQAIAELARTADEMAAAPQIIRDSVA
DKGFAKQSRPWLEAMEVWGGALQKTAAGLDAANRGDTQAPALFAEAAAHAAVAAVVPSIPGATRFDGPVKIADGVLDRFI
AQAPRLIAYRVPAVADSAAAK
>Mature_660_residues
TRRNSKPGVRLLSVLVALGMAAPALAQAVTEPVTQPAIYPTPVSITLDGATIALGRSVVLVVAPGADKATVALVRSILSS
AGVTKMATATRLPATLDRPHIVLGTGDAAVVRDALARSKARQDTHKEGYTLASVALDGGSLITLAGHDDDGLFHAAQTLR
QLVERPAIPTLTIHDYPAMPIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWRAPYPKATLKALG
QLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYTKWNCERDKTAFGESGAQAAGI
AQSHLLNLVQADLVARHDATSELIMVPTEYYDAKESPYKEALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRKT
LLWDNYPVNDFETSAGRLLMAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGLTAFAWNDKDYDAQRTWHAAARDLAG
GDARVTAALLIFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAIALGDAAARTQAIAELARTADEMAAAPQIIRDSVAD
KGFAKQSRPWLEAMEVWGGALQKTAAGLDAANRGDTQAPALFAEAAAHAAVAAVVPSIPGATRFDGPVKIADGVLDRFIA
QAPRLIAYRVPAVADSAAAK

Specific function: Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fibronectin type-III domain [H]

Homologues:

Organism=Homo sapiens, GI215490056, Length=310, Percent_Identity=30.9677419354839, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI11024698, Length=279, Percent_Identity=32.6164874551971, Blast_Score=154, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI193211004, Length=318, Percent_Identity=29.2452830188679, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI193211002, Length=314, Percent_Identity=28.6624203821656, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24648670, Length=297, Percent_Identity=29.2929292929293, Blast_Score=130, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR011496
- InterPro:   IPR008965
- InterPro:   IPR000421
- InterPro:   IPR018452
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR008979
- InterPro:   IPR017853
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00754 F5_F8_type_C; PF00041 fn3; PF02838 Glyco_hydro_20b; PF07555 NAGidase [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 70752; Mature: 70621

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRNSKPGVRLLSVLVALGMAAPALAQAVTEPVTQPAIYPTPVSITLDGATIALGRSVV
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCEEE
LVVAPGADKATVALVRSILSSAGVTKMATATRLPATLDRPHIVLGTGDAAVVRDALARSK
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHH
ARQDTHKEGYTLASVALDGGSLITLAGHDDDGLFHAAQTLRQLVERPAIPTLTIHDYPAM
HHHHHHHCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWRAPYPKATLKAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHH
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYT
HHHHHHHCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCEEC
KWNCERDKTAFGESGAQAAGIAQSHLLNLVQADLVARHDATSELIMVPTEYYDAKESPYK
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHH
EALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRKTLLWDNYPVNDFETSAGRLL
HHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCEE
MAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGLTAFAWNDKDYDAQRTWHAAARDLA
ECCHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCC
GGDARVTAALLIFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAIALGDAAARTQAIAE
CCCHHHEEEEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LARTADEMAAAPQIIRDSVADKGFAKQSRPWLEAMEVWGGALQKTAAGLDAANRGDTQAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ALFAEAAAHAAVAAVVPSIPGATRFDGPVKIADGVLDRFIAQAPRLIAYRVPAVADSAAA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
K
C
>Mature Secondary Structure 
TRRNSKPGVRLLSVLVALGMAAPALAQAVTEPVTQPAIYPTPVSITLDGATIALGRSVV
CCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCEEE
LVVAPGADKATVALVRSILSSAGVTKMATATRLPATLDRPHIVLGTGDAAVVRDALARSK
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHH
ARQDTHKEGYTLASVALDGGSLITLAGHDDDGLFHAAQTLRQLVERPAIPTLTIHDYPAM
HHHHHHHCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PIRGTIEGFYGAPWSMSDRSKHIDFLARTKANTFIYSPKDDPYARDRWRAPYPKATLKAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHH
GQLAATAKRNHVDFVYAISPGPTVCFSDPADAKALLRKFDAFRALGVRSFYVALDDIEYT
HHHHHHHCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEEEECCEEC
KWNCERDKTAFGESGAQAAGIAQSHLLNLVQADLVARHDATSELIMVPTEYYDAKESPYK
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHH
EALRKHLDPKIVVQWTGTDVVPPAISIPDARAATKAFGRKTLLWDNYPVNDFETSAGRLL
HHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCEE
MAPYARREAGLSAELSGIVSNPMNQEVPSRVAVMGLTAFAWNDKDYDAQRTWHAAARDLA
ECCHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCC
GGDARVTAALLIFFDTQHLAPTFGSQPWQEQAPRLKAVLDHVREAIALGDAAARTQAIAE
CCCHHHEEEEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LARTADEMAAAPQIIRDSVADKGFAKQSRPWLEAMEVWGGALQKTAAGLDAANRGDTQAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ALFAEAAAHAAVAAVVPSIPGATRFDGPVKIADGVLDRFIAQAPRLIAYRVPAVADSAAA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA