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The map label for this gene is ubiB [C]

Identifier: 84621727

GI number: 84621727

Start: 76360

End: 78084

Strand: Direct

Name: ubiB [C]

Synonym: XOO_0070

Alternate gene names: 84621727

Gene position: 76360-78084 (Clockwise)

Preceding gene: 84621724

Following gene: 84621730

Centisome position: 1.55

GC content: 64.12

Gene sequence:

>1725_bases
ATGGCCTTGATTCAGAACGACCCGCACCGCGCGCCAGCCCAGGCCACAGGGCCGGCAGATCACGCCGTGGTCGGCGGAAT
GAGCCGGCGCACGCAGATACTGCGCTTGTTGTTGCGCTATCGCGGCTCGGGCGTGTTCGCCGGCATGCATCTGGATCCGG
CGGCCATCAACGAATACGAAGTGCCCGCAGAAGGCACACCGGACCAGTTCGTCTCCGACCTTGAATCGCTCGGCCCCACC
TTCGTCAAGCTAGGCCAGATGCTATCCACCCGGCCGGACATCGTGCCGCCGGAGTTCGCCACCGCACTGGAACGCATGCA
GGAGAACACCAGCTCGGTGCCGGTGGAGCACATCCGCCAGATCATCGAAGAAGAACTCGGTGTGTCGGTCAACAAGGCGT
TCTCGCATTTCGACCCGGTACCGCTGGGCTGCGCCTCGTTGGCGCAAGTGCACCGTGCCGCGTTACGCGACGGCACGCCG
GTGGCGATCAAGGTGCAAAAACCCGAAGTGGCCGCACAGGTGCGCTCGGACATGGAGGTGCTCAAGAGCTTCGCGACCGC
TGCAGACCGCCTCACCGGCATCGGTCGCCGGGTGCGCTTTGCCGATTGGCTAGGCGAATTCGGCAAGACGCTGCGCGCCG
AACTCAACTACCAGGACGAGGCTGAAACGCTGGTGCGCTTCGGCAAGCACCTCAAACCGTTTCCACAGTTGTGGGTGCCG
CAACCGATCTGGGACCTGAGCAGCCGCCGCGTCCTGACCATGCAGCTGGCCGAAGGCGTGCGCGTGGACAAAATCTCCGG
GCTGCGCCGCACCGAACAGCCGATGGATGGCTTGGCTGCCGAACTGGTCAAGGGGTATCTGGACCAGATGTTCGTGCATG
GCGAAATCCACGCCGACCCGCACCCAGGCAACCTGCGCGTGCTGCAGGACGGGCGCCTGGCCATTTTCGACCTGGGCATG
GTGGCGCACGTGCCGCCGCGCTTGCGCGAGCGCTTACTCAAATTATTGTTCGCCGCCGTCGATGGCCGCGGCGAAGAAGT
GGCCGAAGAGACCATCGCGCTCAGCACGCGGCTGGAGGATTACGACGAAGAACGCTACCAGCGCGAGACCGGGCAGATGA
TCGCGCGCTATGCAGCGCACGATGCCACCTCCGAAGGCCGCGTGGTGCTGGACCTGGTGCGCATCGCCACCTCCACCGGT
CTGCGTACGCCGCCGGAACTGAGCCTGCTCGGCAAGACGCTATTGAATCTGGAAGGCGTGTGCCGCGCCTTGTCGCCCAC
GCTTGACACGCGCCGCATCGTCGAACGTCATCTGCAACACGTGATGCGCGCACGCCTGAAAAAATCCATGTCCGCCGCCA
ACCTGGCCAGCGAGGCGATGGAATTGCAGCATCTGGTGCGCGAAGGCCCGCGCCGCATCTCGGAGATTCTGTCGCTAGCT
GCGGAAAACCGCCTGCAGATGCGCGTCACCGGGCTGGAAGAATCGCATCTGATGGAAAGCCTGCAGAAAATCGCCAACCG
CGTTGCAGCGGGTATCGTCACTGCTGCGCTGATCATGGCCTCGGCGCAGATGATGCGCATCGACACCGGCTTGAAGTTGT
GGGGATATCCCGCGATCGCGATGGTGCTATTCCTGCTTGGCGTTGTGCTGGGGCTGGGCATCGTGGTCAGTGCACTGCTG
TTCGACCGCCGCGTGCGAGCGCGCGAAGAGCGTGGGCATCGTTAG

Upstream 100 bases:

>100_bases
CGACCTTGGGCAGGCGTGCGTGCAGCGTGCAGGAGCGCACGGATTCACCAAGCGACGACCCGGCACTGGCCACACTCGCC
GCCTGCATGACGCCCCGGAG

Downstream 100 bases:

>100_bases
GGCCTGTTAACACATCCGAAGCCCATCGACGACCAGAACGAAGCTGAGGAAGCCAAGGAACATGACATCCAGCTTCTCGA
AGCGCGTGAAAATCCGTCGG

Product: ABC transporter substrate binding protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MALIQNDPHRAPAQATGPADHAVVGGMSRRTQILRLLLRYRGSGVFAGMHLDPAAINEYEVPAEGTPDQFVSDLESLGPT
FVKLGQMLSTRPDIVPPEFATALERMQENTSSVPVEHIRQIIEEELGVSVNKAFSHFDPVPLGCASLAQVHRAALRDGTP
VAIKVQKPEVAAQVRSDMEVLKSFATAADRLTGIGRRVRFADWLGEFGKTLRAELNYQDEAETLVRFGKHLKPFPQLWVP
QPIWDLSSRRVLTMQLAEGVRVDKISGLRRTEQPMDGLAAELVKGYLDQMFVHGEIHADPHPGNLRVLQDGRLAIFDLGM
VAHVPPRLRERLLKLLFAAVDGRGEEVAEETIALSTRLEDYDEERYQRETGQMIARYAAHDATSEGRVVLDLVRIATSTG
LRTPPELSLLGKTLLNLEGVCRALSPTLDTRRIVERHLQHVMRARLKKSMSAANLASEAMELQHLVREGPRRISEILSLA
AENRLQMRVTGLEESHLMESLQKIANRVAAGIVTAALIMASAQMMRIDTGLKLWGYPAIAMVLFLLGVVLGLGIVVSALL
FDRRVRAREERGHR

Sequences:

>Translated_574_residues
MALIQNDPHRAPAQATGPADHAVVGGMSRRTQILRLLLRYRGSGVFAGMHLDPAAINEYEVPAEGTPDQFVSDLESLGPT
FVKLGQMLSTRPDIVPPEFATALERMQENTSSVPVEHIRQIIEEELGVSVNKAFSHFDPVPLGCASLAQVHRAALRDGTP
VAIKVQKPEVAAQVRSDMEVLKSFATAADRLTGIGRRVRFADWLGEFGKTLRAELNYQDEAETLVRFGKHLKPFPQLWVP
QPIWDLSSRRVLTMQLAEGVRVDKISGLRRTEQPMDGLAAELVKGYLDQMFVHGEIHADPHPGNLRVLQDGRLAIFDLGM
VAHVPPRLRERLLKLLFAAVDGRGEEVAEETIALSTRLEDYDEERYQRETGQMIARYAAHDATSEGRVVLDLVRIATSTG
LRTPPELSLLGKTLLNLEGVCRALSPTLDTRRIVERHLQHVMRARLKKSMSAANLASEAMELQHLVREGPRRISEILSLA
AENRLQMRVTGLEESHLMESLQKIANRVAAGIVTAALIMASAQMMRIDTGLKLWGYPAIAMVLFLLGVVLGLGIVVSALL
FDRRVRAREERGHR
>Mature_573_residues
ALIQNDPHRAPAQATGPADHAVVGGMSRRTQILRLLLRYRGSGVFAGMHLDPAAINEYEVPAEGTPDQFVSDLESLGPTF
VKLGQMLSTRPDIVPPEFATALERMQENTSSVPVEHIRQIIEEELGVSVNKAFSHFDPVPLGCASLAQVHRAALRDGTPV
AIKVQKPEVAAQVRSDMEVLKSFATAADRLTGIGRRVRFADWLGEFGKTLRAELNYQDEAETLVRFGKHLKPFPQLWVPQ
PIWDLSSRRVLTMQLAEGVRVDKISGLRRTEQPMDGLAAELVKGYLDQMFVHGEIHADPHPGNLRVLQDGRLAIFDLGMV
AHVPPRLRERLLKLLFAAVDGRGEEVAEETIALSTRLEDYDEERYQRETGQMIARYAAHDATSEGRVVLDLVRIATSTGL
RTPPELSLLGKTLLNLEGVCRALSPTLDTRRIVERHLQHVMRARLKKSMSAANLASEAMELQHLVREGPRRISEILSLAA
ENRLQMRVTGLEESHLMESLQKIANRVAAGIVTAALIMASAQMMRIDTGLKLWGYPAIAMVLFLLGVVLGLGIVVSALLF
DRRVRAREERGHR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=228, Percent_Identity=35.9649122807018, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI41393593, Length=278, Percent_Identity=31.6546762589928, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI217035081, Length=183, Percent_Identity=36.6120218579235, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI27363457, Length=411, Percent_Identity=24.5742092457421, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI34147522, Length=296, Percent_Identity=26.3513513513513, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI217416386, Length=388, Percent_Identity=24.2268041237113, Blast_Score=97, Evalue=5e-20,
Organism=Escherichia coli, GI2367309, Length=379, Percent_Identity=30.3430079155673, Blast_Score=160, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17559152, Length=275, Percent_Identity=29.8181818181818, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32565180, Length=312, Percent_Identity=28.8461538461538, Blast_Score=129, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323282, Length=296, Percent_Identity=28.0405405405405, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=290, Percent_Identity=25.8620689655172, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=257, Percent_Identity=26.0700389105058, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI22024280, Length=254, Percent_Identity=30.7086614173228, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24662575, Length=268, Percent_Identity=27.2388059701493, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859849, Length=245, Percent_Identity=31.8367346938775, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63656; Mature: 63524

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIQNDPHRAPAQATGPADHAVVGGMSRRTQILRLLLRYRGSGVFAGMHLDPAAINEYE
CCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCC
VPAEGTPDQFVSDLESLGPTFVKLGQMLSTRPDIVPPEFATALERMQENTSSVPVEHIRQ
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
IIEEELGVSVNKAFSHFDPVPLGCASLAQVHRAALRDGTPVAIKVQKPEVAAQVRSDMEV
HHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHH
LKSFATAADRLTGIGRRVRFADWLGEFGKTLRAELNYQDEAETLVRFGKHLKPFPQLWVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
QPIWDLSSRRVLTMQLAEGVRVDKISGLRRTEQPMDGLAAELVKGYLDQMFVHGEIHADP
CCCCCCCCCEEEHHHHHCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCEEECCC
HPGNLRVLQDGRLAIFDLGMVAHVPPRLRERLLKLLFAAVDGRGEEVAEETIALSTRLED
CCCCEEEEECCCEEEEECCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YDEERYQRETGQMIARYAAHDATSEGRVVLDLVRIATSTGLRTPPELSLLGKTLLNLEGV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
CRALSPTLDTRRIVERHLQHVMRARLKKSMSAANLASEAMELQHLVREGPRRISEILSLA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENRLQMRVTGLEESHLMESLQKIANRVAAGIVTAALIMASAQMMRIDTGLKLWGYPAIA
HCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
MVLFLLGVVLGLGIVVSALLFDRRVRAREERGHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALIQNDPHRAPAQATGPADHAVVGGMSRRTQILRLLLRYRGSGVFAGMHLDPAAINEYE
CCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCC
VPAEGTPDQFVSDLESLGPTFVKLGQMLSTRPDIVPPEFATALERMQENTSSVPVEHIRQ
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
IIEEELGVSVNKAFSHFDPVPLGCASLAQVHRAALRDGTPVAIKVQKPEVAAQVRSDMEV
HHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHH
LKSFATAADRLTGIGRRVRFADWLGEFGKTLRAELNYQDEAETLVRFGKHLKPFPQLWVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
QPIWDLSSRRVLTMQLAEGVRVDKISGLRRTEQPMDGLAAELVKGYLDQMFVHGEIHADP
CCCCCCCCCEEEHHHHHCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCEEECCC
HPGNLRVLQDGRLAIFDLGMVAHVPPRLRERLLKLLFAAVDGRGEEVAEETIALSTRLED
CCCCEEEEECCCEEEEECCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YDEERYQRETGQMIARYAAHDATSEGRVVLDLVRIATSTGLRTPPELSLLGKTLLNLEGV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
CRALSPTLDTRRIVERHLQHVMRARLKKSMSAANLASEAMELQHLVREGPRRISEILSLA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENRLQMRVTGLEESHLMESLQKIANRVAAGIVTAALIMASAQMMRIDTGLKLWGYPAIA
HCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
MVLFLLGVVLGLGIVVSALLFDRRVRAREERGHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]