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The map label for this gene is pdx1

Identifier: 84488902

GI number: 84488902

Start: 86551

End: 87438

Strand: Direct

Name: pdx1

Synonym: Msp_0072

Alternate gene names: 84488902

Gene position: 86551-87438 (Clockwise)

Preceding gene: 84488901

Following gene: 84488903

Centisome position: 4.9

GC content: 36.49

Gene sequence:

>888_bases
ATGATACATGGAACAAAAGTATTAAAAGAAGGATTCGCTAAAATGACAAAAGGCGGAGTTATTATGGATGTAGTAAATGC
AGAACAAGCAGCTATAGCTGAAGATGCAGGAGCAGTATCTGTAATGGCTTTAGAAAGAGTACCATCTGATATAAGAAAAG
CTGGTGGAGTAGCAAGAATGGCTGATCCATCAAAAGTAATTGAAATTATGGATGCAGTAGATATTCCTGTAATGGCAAAA
GTAAGAATTGGTCACTTTGTAGAAGCACAAGTACTCCAATCATTAGGAGTAGATATGATAGATGAAAGTGAAGTATTAAC
ACAAGCAGATGAAGACTTCCATATAGACAAAGAACAATTCACAATTCCATTTGTATGTGGGGCAAGAGACCTTGGAGAAG
CTCTAAGAAGAGTAGATGAAGGGGCAGCAATGATAAGAACCAAAGGTGAAGCTGGTACTGGAAATGTTGTAGAAGCAGTA
AGACACATGAGAACAATTCAAGGTGCTATAAGAGAAATTGAAAATAAAACAGAAGAAGAATTATGGCAAGTAGCTCGTGA
AATTAATGCACCAAGAGAATTAGTAAAATTAACAGCAGAAAAAGGAAGAATTCCTGTAGTTAACTTCTCAGCAGGTGGAA
TAGCAACACCAGCAGATGCAGCATTAATGATGCAATTAGGAGCAGATGGAGTATTTGTAGGTTCAGGTATTTTCAAATCA
GAAAACCCGGAACTTGTAGCAAAAGCAGTAGTTGAAGCAACAGCTCACTATGAAGATGCAGATTTAATTGCAGATGTATC
AACTGATTTAGGTGCAGCAATGCCTGGTATTGATATTAATGAAATACCAGAAGAAGAAAGATTACAAAACAGAGGAAACT
TAATATAA

Upstream 100 bases:

>100_bases
AAATTATTAATAACAAAAATATTTATTGTTATAAATTTATTATTTATTATATATATTATAGAATTCATAGAATTTATCAA
CTAGAAGGAGAATAAAAATA

Downstream 100 bases:

>100_bases
GTTCTCTTCTTTATTTTTCTTTATAAATAAAATACTATTTTTTTTATATAACTTAGGAGATTATATATTTAATATTCAAG
AGGTGAAGTTGTGGATAAAA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MIHGTKVLKEGFAKMTKGGVIMDVVNAEQAAIAEDAGAVSVMALERVPSDIRKAGGVARMADPSKVIEIMDAVDIPVMAK
VRIGHFVEAQVLQSLGVDMIDESEVLTQADEDFHIDKEQFTIPFVCGARDLGEALRRVDEGAAMIRTKGEAGTGNVVEAV
RHMRTIQGAIREIENKTEEELWQVAREINAPRELVKLTAEKGRIPVVNFSAGGIATPADAALMMQLGADGVFVGSGIFKS
ENPELVAKAVVEATAHYEDADLIADVSTDLGAAMPGIDINEIPEEERLQNRGNLI

Sequences:

>Translated_295_residues
MIHGTKVLKEGFAKMTKGGVIMDVVNAEQAAIAEDAGAVSVMALERVPSDIRKAGGVARMADPSKVIEIMDAVDIPVMAK
VRIGHFVEAQVLQSLGVDMIDESEVLTQADEDFHIDKEQFTIPFVCGARDLGEALRRVDEGAAMIRTKGEAGTGNVVEAV
RHMRTIQGAIREIENKTEEELWQVAREINAPRELVKLTAEKGRIPVVNFSAGGIATPADAALMMQLGADGVFVGSGIFKS
ENPELVAKAVVEATAHYEDADLIADVSTDLGAAMPGIDINEIPEEERLQNRGNLI
>Mature_295_residues
MIHGTKVLKEGFAKMTKGGVIMDVVNAEQAAIAEDAGAVSVMALERVPSDIRKAGGVARMADPSKVIEIMDAVDIPVMAK
VRIGHFVEAQVLQSLGVDMIDESEVLTQADEDFHIDKEQFTIPFVCGARDLGEALRRVDEGAAMIRTKGEAGTGNVVEAV
RHMRTIQGAIREIENKTEEELWQVAREINAPRELVKLTAEKGRIPVVNFSAGGIATPADAALMMQLGADGVFVGSGIFKS
ENPELVAKAVVEATAHYEDADLIADVSTDLGAAMPGIDINEIPEEERLQNRGNLI

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321049, Length=279, Percent_Identity=63.4408602150538, Blast_Score=350, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6323743, Length=276, Percent_Identity=61.9565217391304, Blast_Score=350, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6323996, Length=279, Percent_Identity=63.0824372759857, Blast_Score=350, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_METST (Q2NI73)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447134.1
- ProteinModelPortal:   Q2NI73
- SMR:   Q2NI73
- STRING:   Q2NI73
- GeneID:   3855190
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0072
- NMPDR:   fig|339860.6.peg.71
- eggNOG:   arNOG04544
- HOGENOM:   HBG292342
- OMA:   VGINIDE
- PhylomeDB:   Q2NI73
- ProtClustDB:   PRK04180
- BioCyc:   MSTA339860:MSP_0072-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31625; Mature: 31625

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHGTKVLKEGFAKMTKGGVIMDVVNAEQAAIAEDAGAVSVMALERVPSDIRKAGGVARM
CCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCHHHHHHHHCCHHHHHHCCCCCC
ADPSKVIEIMDAVDIPVMAKVRIGHFVEAQVLQSLGVDMIDESEVLTQADEDFHIDKEQF
CCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHE
TIPFVCGARDLGEALRRVDEGAAMIRTKGEAGTGNVVEAVRHMRTIQGAIREIENKTEEE
EEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
LWQVAREINAPRELVKLTAEKGRIPVVNFSAGGIATPADAALMMQLGADGVFVGSGIFKS
HHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCCCC
ENPELVAKAVVEATAHYEDADLIADVSTDLGAAMPGIDINEIPEEERLQNRGNLI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MIHGTKVLKEGFAKMTKGGVIMDVVNAEQAAIAEDAGAVSVMALERVPSDIRKAGGVARM
CCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCHHHHHHHHCCHHHHHHCCCCCC
ADPSKVIEIMDAVDIPVMAKVRIGHFVEAQVLQSLGVDMIDESEVLTQADEDFHIDKEQF
CCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCHHHE
TIPFVCGARDLGEALRRVDEGAAMIRTKGEAGTGNVVEAVRHMRTIQGAIREIENKTEEE
EEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHH
LWQVAREINAPRELVKLTAEKGRIPVVNFSAGGIATPADAALMMQLGADGVFVGSGIFKS
HHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCCCC
ENPELVAKAVVEATAHYEDADLIADVSTDLGAAMPGIDINEIPEEERLQNRGNLI
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA