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The map label for this gene is argF-1 [H]

Identifier: 83721357

GI number: 83721357

Start: 841613

End: 842542

Strand: Reverse

Name: argF-1 [H]

Synonym: BTH_I0732

Alternate gene names: 83721357

Gene position: 842542-841613 (Counterclockwise)

Preceding gene: 83719209

Following gene: 83718842

Centisome position: 22.12

GC content: 62.47

Gene sequence:

>930_bases
ATGACCGCCAAAACCATTCGTCACTACCTGCAGTTCAAGGATTTCTCGCTGGAAGACTACGAGTACGTGCTCGAACGCAC
GGGTATCCTGAAGCGCAAATTCAAGAACTACGAGACCTATCACCCGCTGCACGACCGCACGCTCGCGATGATCTTCGAGA
AGAGCTCGACGCGCACGCGCCTGTCGTTCGAGGCCGGGATCTTTCAGCTAGGCGGCCACGCCGTGTTCATGAGCACGCGC
GACACGCAGCTCGGCCGCGGCGAACCCGTCGAGGATTCGGCGCAGGTGATCTCGCGGATGGTCGACATCATCATGATCCG
CACGTTCGAGCAGGACATCATCCAGCGCTTCGCCGAAAATTCGCGCGTACCGGTGATCAATGGCCTGACGAACGAGTACC
ACCCGTGCCAGGTGCTCGCCGACATCTTCACGTATTACGAGCACCGCGGCCCGATTCGCGGCAAGACGGTCGCCTGGGTC
GGCGACGCGAACAACATGCTGTACACGTGGATCCAGGCCGCGCGCATCCTCGACTTCAAGCTGCAGCTGTCGACGCCGCC
CGGCTATGCGCTCGACGCGAAGCTCGTCGATGCCGAAAGCGCGCCGTTCTACCAGGTGTTCGACGATCCGAACGAAGCGT
GCAAGGGTGCGGATCTCGTCACGACCGACGTGTGGACGAGCATGGGCTTCGAGGCGGAGAACGAGGCGCGCAAGCGGGCG
TTCGCCGACTGGTGCGTCGACGAGGAAATGATGTCGCACGCGAATTCCGACGCGCTCTTCATGCACTGCCTGCCCGCGCA
TCGCGGCGAGGAAGTAACGGCGGGCGTGATCGACGGCCCGCAAAGCGTCGTGTGGGACGAGGCGGAAAACCGTCTGCACG
TGCAGAAGGCGCTCATGGAGTTCCTGTTGCTCGGGCGCCTGAACCACTGA

Upstream 100 bases:

>100_bases
CAAAGCGTAAAAAATCCTTTATGCTGGTTCGAGTTATCACATCCGACGGCGGCGCCGTCCGGCGCGTTCGCCGCCGGTTG
AGTCCGCCGTATTTCGTTTC

Downstream 100 bases:

>100_bases
TTTGCCGGCGCGCACCGCGGCTGCGGCGCCGATCGGCACGCGACGCGGCGCCCGCGAAACGAGGCGCCCGCGCACTCGCC
TTCGGCGCAAGAAGAAACCT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWV
GDANNMLYTWIQAARILDFKLQLSTPPGYALDAKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKRA
FADWCVDEEMMSHANSDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH

Sequences:

>Translated_309_residues
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTR
DTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWV
GDANNMLYTWIQAARILDFKLQLSTPPGYALDAKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKRA
FADWCVDEEMMSHANSDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH
>Mature_308_residues
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRD
TQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVG
DANNMLYTWIQAARILDFKLQLSTPPGYALDAKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKRAF
ADWCVDEEMMSHANSDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLNH

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=39.8026315789474, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI18105007, Length=305, Percent_Identity=25.2459016393443, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=35.6923076923077, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786469, Length=326, Percent_Identity=35.5828220858896, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI2367364, Length=307, Percent_Identity=27.0358306188925, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=298, Percent_Identity=27.5167785234899, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=32.9268292682927, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6322331, Length=271, Percent_Identity=26.1992619926199, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24642586, Length=311, Percent_Identity=26.6881028938907, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35414; Mature: 35282

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAEN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVGDANNMLYTWIQAARILDFK
CCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEE
LQLSTPPGYALDAKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKRA
EEECCCCCCEEEEEEECCCCCCEEEEECCHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHH
FADWCVDEEMMSHANSDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHCCCHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLNH
HHHHHCCCC
>Mature Secondary Structure 
TAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTR
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEE
LSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDIIQRFAEN
EEECCCCEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRVPVINGLTNEYHPCQVLADIFTYYEHRGPIRGKTVAWVGDANNMLYTWIQAARILDFK
CCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEE
LQLSTPPGYALDAKLVDAESAPFYQVFDDPNEACKGADLVTTDVWTSMGFEAENEARKRA
EEECCCCCCEEEEEEECCCCCCEEEEECCHHHHHCCCCEEEHHHHHHCCCCCHHHHHHHH
FADWCVDEEMMSHANSDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALME
HHHHCCCHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FLLLGRLNH
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA