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The map label for this gene is xapR [H]

Identifier: 83721216

GI number: 83721216

Start: 3798441

End: 3799340

Strand: Direct

Name: xapR [H]

Synonym: BTH_I3334

Alternate gene names: 83721216

Gene position: 3798441-3799340 (Clockwise)

Preceding gene: 83719180

Following gene: 83721396

Centisome position: 99.72

GC content: 72.0

Gene sequence:

>900_bases
ATGGACCTGACTCTGCTTCGCGCGTTCGTCGCGGTCGCGCGCGAGGGCAACCTCACGCGCGCGGCGGCGCAACTGCATCT
GACACAGCCCGCCGTCAGCCTGCAGATCAAGAACCTGCAGGACTTGCTCGGCGTCGCGCTGTTCGCGCGCACGTCGCGCG
GGCTCGCGCTCACGCGCGACGGCCAGGCGCTGCTGCCGCACGCGGAACGCGCGCTCGACGCGGCGGCCGACGTGAAGCGC
GCCGCCGCCGCGCTCAGGCACGAGGTGCGCGGCCGGCTGCGGATCGGCACGATTCTCGACCCCGAATTCCTGCGGCTCGG
CGGCTTCCTGAAGCGGCTCGTCGAGGCGCATCCGCAGATCGAGACGGCACTGCGGCACGGCATGTCCGGCTGGGTGCTCG
ACGGAGTCCGTGCGCGCGAGCTCGACGTCGGCTACTACATCGGCCGGCCGGAGGAGGACGATCCGCGCGACGCCGAGCGC
TTCCACACCGTGACGCTCACGCAGTTCCGCTATCGGGTGCTCGCACCCGCCGGCTGGAAGGAGCGCGTGCAGCGCGCACG
CACGTGGCGCGAGCTCGCGGCGCTGCCGTGGATCTGGACGCCCGCCGCCTCCGCGCACCATCGGCTTCTGTCGCGCCGCT
TCGCCGATGCGGGCGCGCAGCCCGTCAAGGTTGCGGAAGTCGATCAGGAGACGTCCATGCTCGATCTCGTCAAGTCGGGC
GTCGGCCTGACGCTCGCGCGCGACTCGATCGCGCTGCGGGAGGCGCACGCGCACGCGCTCACGATCGTCGAGCATGTCGC
GGTGCCCGCCGAACTCACGTTCGTCACGCTCGCCGAGCGCCGCGACGAACCGGCGATCGCGGCCGCGCTGCGCCTCATCG
ACGAGCAATGGGCGATATGA

Upstream 100 bases:

>100_bases
CGCGTATCGCGCGCTTCGGGAATGAAGCGTACCCGCCGGCCCCATTCGCGATCCAATGAGTTATGCTCAATTGCGTTATA
AGCCGCGCTAATATTGCTCG

Downstream 100 bases:

>100_bases
GCGCCGCTGATGATGGGCGACGCGGCGCGCGGCCTTTTCGCATCGCGTCAAAATCGCTCGCGCCCCGATAGAATGGGAGC
TTCTGGATGGTTTGTCCGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGVALFARTSRGLALTRDGQALLPHAERALDAAADVKR
AAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQIETALRHGMSGWVLDGVRARELDVGYYIGRPEEDDPRDAER
FHTVTLTQFRYRVLAPAGWKERVQRARTWRELAALPWIWTPAASAHHRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLAERRDEPAIAAALRLIDEQWAI

Sequences:

>Translated_299_residues
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGVALFARTSRGLALTRDGQALLPHAERALDAAADVKR
AAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQIETALRHGMSGWVLDGVRARELDVGYYIGRPEEDDPRDAER
FHTVTLTQFRYRVLAPAGWKERVQRARTWRELAALPWIWTPAASAHHRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLAERRDEPAIAAALRLIDEQWAI
>Mature_299_residues
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGVALFARTSRGLALTRDGQALLPHAERALDAAADVKR
AAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQIETALRHGMSGWVLDGVRARELDVGYYIGRPEEDDPRDAER
FHTVTLTQFRYRVLAPAGWKERVQRARTWRELAALPWIWTPAASAHHRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLAERRDEPAIAAALRLIDEQWAI

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=27.2, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=36.8794326241135, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=284, Percent_Identity=24.2957746478873, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=25.4032258064516, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788887, Length=250, Percent_Identity=30, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081904, Length=154, Percent_Identity=35.7142857142857, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI48994962, Length=158, Percent_Identity=32.9113924050633, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082132, Length=149, Percent_Identity=30.8724832214765, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787879, Length=105, Percent_Identity=39.0476190476191, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=155, Percent_Identity=31.6129032258064, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789173, Length=63, Percent_Identity=52.3809523809524, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33173; Mature: 33173

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGVALFARTSRGLALTRD
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHHCCCCEEEECC
GQALLPHAERALDAAADVKRAAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCHH
ETALRHGMSGWVLDGVRARELDVGYYIGRPEEDDPRDAERFHTVTLTQFRYRVLAPAGWK
HHHHHCCCCCCEECCCCCEEEECCEEECCCCCCCCCHHHHHEEEEHHHHHHHHCCCCCHH
ERVQRARTWRELAALPWIWTPAASAHHRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
HHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCC
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLAERRDEPAIAAALRLIDEQWAI
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGVALFARTSRGLALTRD
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHHCCCCEEEECC
GQALLPHAERALDAAADVKRAAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCHH
ETALRHGMSGWVLDGVRARELDVGYYIGRPEEDDPRDAERFHTVTLTQFRYRVLAPAGWK
HHHHHCCCCCCEECCCCCEEEECCEEECCCCCCCCCHHHHHEEEEHHHHHHHHCCCCCHH
ERVQRARTWRELAALPWIWTPAASAHHRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
HHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCC
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLAERRDEPAIAAALRLIDEQWAI
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]