| Definition | Burkholderia thailandensis E264 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_007651 |
| Length | 3,809,201 |
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The map label for this gene is polS [H]
Identifier: 83721212
GI number: 83721212
Start: 796814
End: 797590
Strand: Direct
Name: polS [H]
Synonym: BTH_I0692
Alternate gene names: 83721212
Gene position: 796814-797590 (Clockwise)
Preceding gene: 83719731
Following gene: 83719361
Centisome position: 20.92
GC content: 69.63
Gene sequence:
>777_bases GTGAGACTGCAGGAGAAGGTCGCGATCCTGACGGGCGCGGCAAGCGGTATCGGCGAAGCCGTGGCGCGACGCTATCTGGA AGAGGGCGCGCGCTGCGTGCTCGTCGATCTGAAGCCGGCCGACGGCGCGCTCGCCCGGCTCGTCGACGCGCATGCCGGGC GCGCGATCGCCGTTTCGGCGGACGTCACGCGCCGCGACGACATCGCGCGCATCGTCGCCGCAGCCGTCGAGCGCTTCGGC GGCGTCGACATCCTGTTCAACAACGCGGCGCTCTTCGACATGCGTCCGCTCCTCGACGAATCGTGGGACGTGTTCGATCG CCTGTTCGCGGTCAACGTGAAGGGCATGTTCTTCCTGATGCAGGCGGTGGCGCGGCGCATGGTGGAGCAGGGCCGCGGCG GCAAGATCGTCAACATGTCGTCGCAGGCGGGGCGCCGCGGCGAGGCGCTCGTGTCGCACTACTGCGCGACGAAGGCCGCG GTGCTGAGCTACACGCAATCGGCCGCGCTCGCGCTCGCCAAGCACGGGATCAACGTGAACGGCATCGCGCCGGGCGTCGT CGATACGCCGATGTGGGAGCACGTCGACGCGCTCTTCGCGCGCTACGAGAACCGCCCGCTCGGCGAGAAGAAGCGGCTCG TCGGCGAAGCGGTGCCGCTCGGCCGGATGGGCGTGCCCGACGATCTGACGGGCGCCGCGCTCTTTCTCGCATCGGCGGAC GCCGACTACATCACCGCCCAGACGCTGAACGTCGACGGCGGCAACTGGATGAGCTGA
Upstream 100 bases:
>100_bases TGGTCGATCATTCGTTCGCAAGCAGAGCAAATGATCGGTTAATGAGCGAACGCTCGGCCCGGCGGCCGGCGGCGCGACGT ATAACGAATCGGAGACACCA
Downstream 100 bases:
>100_bases CCTCATGGCCGCGATCGTCGCCGCAGGCGAGCTGCTCGCCGAATTCGTCGCCGCGAAGCGCGGCCAGGGTTTCGCCGCGC CGGGCGAGTTCGCCGGCCCG
Product: sorbitol dehydrogenase
Products: NA
Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSADVTRRDDIARIVAAAVERFG GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLMQAVARRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VLSYTQSAALALAKHGINVNGIAPGVVDTPMWEHVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD ADYITAQTLNVDGGNWMS
Sequences:
>Translated_258_residues MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSADVTRRDDIARIVAAAVERFG GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLMQAVARRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VLSYTQSAALALAKHGINVNGIAPGVVDTPMWEHVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD ADYITAQTLNVDGGNWMS >Mature_258_residues MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSADVTRRDDIARIVAAAVERFG GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLMQAVARRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAA VLSYTQSAALALAKHGINVNGIAPGVVDTPMWEHVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD ADYITAQTLNVDGGNWMS
Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=33.8289962825279, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=34.8659003831418, Blast_Score=122, Evalue=2e-28, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=34.6774193548387, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=33.7552742616034, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=31.9230769230769, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=31.0606060606061, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.1782178217822, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=33.4630350194552, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=29.6442687747036, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI33667109, Length=252, Percent_Identity=31.7460317460317, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=34.4086021505376, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=29.6, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=26.9430051813472, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=25.3275109170306, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=31.2138728323699, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI83715985, Length=182, Percent_Identity=31.3186813186813, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=32.6633165829146, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=34.375, Blast_Score=144, Evalue=5e-36, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=36.2595419847328, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=34.2629482071713, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=33.0708661417323, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=31.7460317460317, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=32.9501915708812, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=35.632183908046, Blast_Score=114, Evalue=8e-27, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=31.0344827586207, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=28.7878787878788, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=33.976833976834, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=28.7937743190661, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=29.6703296703297, Blast_Score=76, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=33.984375, Blast_Score=136, Evalue=1e-32, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=32.0158102766798, Blast_Score=126, Evalue=9e-30, Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=32.9501915708812, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=32.7067669172932, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=32.8125, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=29.5620437956204, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=32.0143884892086, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=30.0751879699248, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=29.7397769516729, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=31.2977099236641, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=28.8888888888889, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.1587301587302, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=28.3088235294118, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=28.2608695652174, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=28.8888888888889, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=27.007299270073, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=30.6273062730627, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=28.7822878228782, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=31.6176470588235, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=30.8300395256917, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17564282, Length=210, Percent_Identity=30, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=29.9610894941634, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=27.037037037037, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=29.6703296703297, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=27.0408163265306, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=30.8755760368664, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=27.0408163265306, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=27.4611398963731, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=27.9693486590038, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=21.875, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=22.9571984435798, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=26.4248704663212, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=25, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193207185, Length=155, Percent_Identity=27.741935483871, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=30.2083333333333, Blast_Score=78, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=256, Percent_Identity=30.078125, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=8e-13, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=35.5731225296443, Blast_Score=130, Evalue=6e-31, Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=33.4600760456274, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=34.251968503937, Blast_Score=117, Evalue=8e-27, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=31.3953488372093, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=31.5175097276265, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=30.5019305019305, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.9850746268657, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=26.4550264550265, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI281364892, Length=200, Percent_Identity=28.5, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24644337, Length=207, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=29.1828793774319, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=28.1407035175879, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24665247, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24665264, Length=201, Percent_Identity=26.865671641791, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24656154, Length=211, Percent_Identity=28.436018957346, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI19922628, Length=211, Percent_Identity=28.436018957346, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641232, Length=208, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.14 [H]
Molecular weight: Translated: 27627; Mature: 27627
Theoretical pI: Translated: 6.95; Mature: 6.95
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSA CCHHHHHHEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEC DVTRRDDIARIVAAAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLM CCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCHHHHHHHH QAVARRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALAKHGINVN HHHHHHHHHCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GIAPGVVDTPMWEHVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCC ADYITAQTLNVDGGNWMS CCEEEEEEEECCCCCCCC >Mature Secondary Structure MRLQEKVAILTGAASGIGEAVARRYLEEGARCVLVDLKPADGALARLVDAHAGRAIAVSA CCHHHHHHEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEC DVTRRDDIARIVAAAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLM CCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCHHHHHHHHHHHCHHHHHHHH QAVARRMVEQGRGGKIVNMSSQAGRRGEALVSHYCATKAAVLSYTQSAALALAKHGINVN HHHHHHHHHCCCCCEEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GIAPGVVDTPMWEHVDALFARYENRPLGEKKRLVGEAVPLGRMGVPDDLTGAALFLASAD CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCC ADYITAQTLNVDGGNWMS CCEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7551049 [H]