Click here to switch to the map view.

The map label for this gene is lpsI [H]

Identifier: 83721125

GI number: 83721125

Start: 2969690

End: 2970598

Strand: Reverse

Name: lpsI [H]

Synonym: BTH_I2608

Alternate gene names: 83721125

Gene position: 2970598-2969690 (Counterclockwise)

Preceding gene: 83721018

Following gene: 83721475

Centisome position: 77.98

GC content: 64.58

Gene sequence:

>909_bases
ATGTATTTTTGCGTATTGTGCCGCATCCGGCGCGCATCGTACCCTTTCATGCGTGTCGCGGCTCATGCCGCGAACGGGCA
ACAGAAGAAAGCGCACCGTCGCGGCAGCATTCGCCGCGCGTGCTTAGAATGGTGCGACGGGTTCGTCGCGCGCGCGAGCC
GCGCGGATCGTCGAGCCGGTTTCCATAGAGGAAGGGACATACAGATGAACAAAGTCTACCCAAGCGCGGCAGCCGCGCTC
GAGGGCGTCGTCCATGACGGGCAGACCTTCGCGGTCGGCGGCTTCGGCCTGTGCGGCATCCCGGAAGCGCTCATCGCGGC
GCTGCGCGACTCGGGCGTGAAGGACATCACCTGCATCAGCAACAACGCGGGCGTCGACGGATTCGGTCTCGGCCTTCTGC
TCGAGACCCGGCAAATCAAGAAGATGATCTCGTCGTACGTCGGCGAGAACAAGGAGTTCGAGCGCCAGTATCTGTCGGGC
GAGCTCGAGCTCGAGTTCACGCCGCAAGGCACGCTTGCCGAGAAGCTGCGCGCGGGCGGCGCGGGCATTCCGGCGTTCTT
CACGCAGACGGGCTACGGCACGGTGATCGCCGAAGGCAAGGAGACGCGCGAGTTCGACGGCAGGCATTACGTGCTCGAGC
CGTCGCTCACGGCGGACGTCGCGCTCGTGAAGGCGTGGAAGGCCGACAAGTCAGGCAACCTGATCTATCGCCGCACCGCG
CGCAACTTCAATCCGATGTGCGCGATGGCGGGCCGGATCACGGTCGCCGAGGTCGAGGAGATCGTCGAGAACGGCGAGCT
CGATCCGGATGCGATCCACACGCCCGGCATTTTCGTGCAGCGGCTCGTGCTCAACGCGACGCCGGAAAAACGCATCGAAC
AACGCGTCGTGCGCGCGAAAGGAGACTGA

Upstream 100 bases:

>100_bases
AGGCCGATCGGCGCGAGATGGAAGGCGGTCTTGTAATCGATGGCGGGCATGGACGCTGACGGGCAGTGATCGGGCGCCGC
GCAAGCGGCGGCGAGTGCTT

Downstream 100 bases:

>100_bases
GATGGCTTGGAATCGTGACCAGATGGCCGCGCGCGCGGCGAAGGAATTGCAGGACGGCTTCTACGTGAACCTCGGCATCG
GGCTGCCGACGCTCGTCGCG

Product: 3-oxoadipate CoA-succinyl transferase subunit alpha

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MYFCVLCRIRRASYPFMRVAAHAANGQQKKAHRRGSIRRACLEWCDGFVARASRADRRAGFHRGRDIQMNKVYPSAAAAL
EGVVHDGQTFAVGGFGLCGIPEALIAALRDSGVKDITCISNNAGVDGFGLGLLLETRQIKKMISSYVGENKEFERQYLSG
ELELEFTPQGTLAEKLRAGGAGIPAFFTQTGYGTVIAEGKETREFDGRHYVLEPSLTADVALVKAWKADKSGNLIYRRTA
RNFNPMCAMAGRITVAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD

Sequences:

>Translated_302_residues
MYFCVLCRIRRASYPFMRVAAHAANGQQKKAHRRGSIRRACLEWCDGFVARASRADRRAGFHRGRDIQMNKVYPSAAAAL
EGVVHDGQTFAVGGFGLCGIPEALIAALRDSGVKDITCISNNAGVDGFGLGLLLETRQIKKMISSYVGENKEFERQYLSG
ELELEFTPQGTLAEKLRAGGAGIPAFFTQTGYGTVIAEGKETREFDGRHYVLEPSLTADVALVKAWKADKSGNLIYRRTA
RNFNPMCAMAGRITVAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
>Mature_302_residues
MYFCVLCRIRRASYPFMRVAAHAANGQQKKAHRRGSIRRACLEWCDGFVARASRADRRAGFHRGRDIQMNKVYPSAAAAL
EGVVHDGQTFAVGGFGLCGIPEALIAALRDSGVKDITCISNNAGVDGFGLGLLLETRQIKKMISSYVGENKEFERQYLSG
ELELEFTPQGTLAEKLRAGGAGIPAFFTQTGYGTVIAEGKETREFDGRHYVLEPSLTADVALVKAWKADKSGNLIYRRTA
RNFNPMCAMAGRITVAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=59.6638655462185, Blast_Score=287, Evalue=8e-78,
Organism=Homo sapiens, GI11545841, Length=238, Percent_Identity=53.781512605042, Blast_Score=242, Evalue=3e-64,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=45.5882352941176, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=266, Percent_Identity=54.1353383458647, Blast_Score=267, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=53.2, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=53.2, Blast_Score=253, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 33182; Mature: 33182

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFCVLCRIRRASYPFMRVAAHAANGQQKKAHRRGSIRRACLEWCDGFVARASRADRRAG
CEEEEEEHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHRGRDIQMNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSGVKDITCIS
CCCCCCEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEC
NNAGVDGFGLGLLLETRQIKKMISSYVGENKEFERQYLSGELELEFTPQGTLAEKLRAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCC
AGIPAFFTQTGYGTVIAEGKETREFDGRHYVLEPSLTADVALVKAWKADKSGNLIYRRTA
CCCCHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECC
RNFNPMCAMAGRITVAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAK
CCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
GD
CC
>Mature Secondary Structure
MYFCVLCRIRRASYPFMRVAAHAANGQQKKAHRRGSIRRACLEWCDGFVARASRADRRAG
CEEEEEEHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHRGRDIQMNKVYPSAAAALEGVVHDGQTFAVGGFGLCGIPEALIAALRDSGVKDITCIS
CCCCCCEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEC
NNAGVDGFGLGLLLETRQIKKMISSYVGENKEFERQYLSGELELEFTPQGTLAEKLRAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCC
AGIPAFFTQTGYGTVIAEGKETREFDGRHYVLEPSLTADVALVKAWKADKSGNLIYRRTA
CCCCHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECC
RNFNPMCAMAGRITVAEVEEIVENGELDPDAIHTPGIFVQRLVLNATPEKRIEQRVVRAK
CCCCCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
GD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]