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The map label for this gene is panB [H]

Identifier: 83720952

GI number: 83720952

Start: 1472209

End: 1472991

Strand: Reverse

Name: panB [H]

Synonym: BTH_I1311

Alternate gene names: 83720952

Gene position: 1472991-1472209 (Counterclockwise)

Preceding gene: 83720017

Following gene: 83719577

Centisome position: 38.67

GC content: 68.97

Gene sequence:

>783_bases
GTGACGGTGCCCAAGCTGCAGGCGATGCGTGAAGCCGGCGAGAAGATCGCCATGCTCACCTGCTACGACGCGAGCTTCGC
CGCCCTCCTCGATCGCGCGAACGTCGACGTGCAACTGATCGGCGATTCGCTCGGCAACGTGCTGCAAGGCCAGACGACGA
CGCTGCCCGTCACGCTCGACGACATCGCGTACCACACCGCCTGCGTCGCGCGCGCGCAGCCGCGCGCGCTCATCGTCGCG
GACCTGCCGTTCGGCACCTACGGCACGCCCGCCGACGCGTTCGCGAGCGCGGTGAAGCTGATGCGCGCGGGCGCGCAGAT
GGTCAAGTTCGAAGGCGGCGAATGGCTCGCCGAAACGGTGCGCTTCCTCGTCGAGCGAGCGGTGCCCGTGTGCGCGCACG
TCGGCCTCACGCCGCAATCGGTGCACGCGTTCGGCGGCTTCAAGGTACAGGGAAAGACGGAAGCGGGCGCCGCGCAATTG
CTGCGCGACGCGCGCGCGGTCGAAGAAGCGGGCGCGCAGCTCATCGTGCTCGAGGCCGTGCCGACGCTCGTCGCGGCGGA
AGTCACGCGCGAGCTGTCGATCCCGACGATCGGCATCGGCGCGGGTGCGGAATGTTCCGGCCAGGTCCTCGTGCTGCACG
ACATGCTCGGCGTGTTCCCCGGCAAACGCCCTCGCTTCGTCAAGGATTTCATGCAGGGACAGCCGAGCATCTTCGCGGCC
GTCGAGGCTTACGTGCGCGCGGTGAAGGACGGCAGCTTCCCCGGGCCCGAGCATTCGTTCTGA

Upstream 100 bases:

>100_bases
TGACCGACGCGCGCACCGTCGCCGAGCGCGGCGCCGCCCTTTTCCTCACCATCGAATCGGACCTCCCATGACCTACCTTC
AGGAATCCAGCCGACCGGCC

Downstream 100 bases:

>100_bases
CGGCGCGGCCGGTTCGCCCCCCCGCGCGCGCAGTCGCCTGCGGAATGCGGCGGCCCGCCGCACTTCGCGAAGCTCAACAA
AAATGCGGCATCCGCACGTG

Product: 3-methyl-2-oxobutanoate hydroxymethyltransferase

Products: NA

Alternate protein names: Ketopantoate hydroxymethyltransferase; KPHMT [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTVPKLQAMREAGEKIAMLTCYDASFAALLDRANVDVQLIGDSLGNVLQGQTTTLPVTLDDIAYHTACVARAQPRALIVA
DLPFGTYGTPADAFASAVKLMRAGAQMVKFEGGEWLAETVRFLVERAVPVCAHVGLTPQSVHAFGGFKVQGKTEAGAAQL
LRDARAVEEAGAQLIVLEAVPTLVAAEVTRELSIPTIGIGAGAECSGQVLVLHDMLGVFPGKRPRFVKDFMQGQPSIFAA
VEAYVRAVKDGSFPGPEHSF

Sequences:

>Translated_260_residues
MTVPKLQAMREAGEKIAMLTCYDASFAALLDRANVDVQLIGDSLGNVLQGQTTTLPVTLDDIAYHTACVARAQPRALIVA
DLPFGTYGTPADAFASAVKLMRAGAQMVKFEGGEWLAETVRFLVERAVPVCAHVGLTPQSVHAFGGFKVQGKTEAGAAQL
LRDARAVEEAGAQLIVLEAVPTLVAAEVTRELSIPTIGIGAGAECSGQVLVLHDMLGVFPGKRPRFVKDFMQGQPSIFAA
VEAYVRAVKDGSFPGPEHSF
>Mature_259_residues
TVPKLQAMREAGEKIAMLTCYDASFAALLDRANVDVQLIGDSLGNVLQGQTTTLPVTLDDIAYHTACVARAQPRALIVAD
LPFGTYGTPADAFASAVKLMRAGAQMVKFEGGEWLAETVRFLVERAVPVCAHVGLTPQSVHAFGGFKVQGKTEAGAAQLL
RDARAVEEAGAQLIVLEAVPTLVAAEVTRELSIPTIGIGAGAECSGQVLVLHDMLGVFPGKRPRFVKDFMQGQPSIFAAV
EAYVRAVKDGSFPGPEHSF

Specific function: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate [H]

COG id: COG0413

COG function: function code H; Ketopantoate hydroxymethyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panB family [H]

Homologues:

Organism=Escherichia coli, GI1786326, Length=259, Percent_Identity=54.0540540540541, Blast_Score=285, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6319653, Length=269, Percent_Identity=36.0594795539033, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003700
- InterPro:   IPR015813 [H]

Pfam domain/function: PF02548 Pantoate_transf [H]

EC number: =2.1.2.11 [H]

Molecular weight: Translated: 27494; Mature: 27363

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPKLQAMREAGEKIAMLTCYDASFAALLDRANVDVQLIGDSLGNVLQGQTTTLPVTLD
CCCCHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCEEEEECHHHHHHHCCCCEEEEEEHH
DIAYHTACVARAQPRALIVADLPFGTYGTPADAFASAVKLMRAGAQMVKFEGGEWLAETV
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHEEECCCHHHHHHH
RFLVERAVPVCAHVGLTPQSVHAFGGFKVQGKTEAGAAQLLRDARAVEEAGAQLIVLEAV
HHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEHH
PTLVAAEVTRELSIPTIGIGAGAECSGQVLVLHDMLGVFPGKRPRFVKDFMQGQPSIFAA
HHHHHHHHHHHCCCCEEECCCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHCCCCHHHHH
VEAYVRAVKDGSFPGPEHSF
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TVPKLQAMREAGEKIAMLTCYDASFAALLDRANVDVQLIGDSLGNVLQGQTTTLPVTLD
CCCHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCEEEEECHHHHHHHCCCCEEEEEEHH
DIAYHTACVARAQPRALIVADLPFGTYGTPADAFASAVKLMRAGAQMVKFEGGEWLAETV
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHEEECCCHHHHHHH
RFLVERAVPVCAHVGLTPQSVHAFGGFKVQGKTEAGAAQLLRDARAVEEAGAQLIVLEAV
HHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEHH
PTLVAAEVTRELSIPTIGIGAGAECSGQVLVLHDMLGVFPGKRPRFVKDFMQGQPSIFAA
HHHHHHHHHHHCCCCEEECCCCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHCCCCHHHHH
VEAYVRAVKDGSFPGPEHSF
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA