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The map label for this gene is yahK [H]

Identifier: 83720893

GI number: 83720893

Start: 183292

End: 184356

Strand: Reverse

Name: yahK [H]

Synonym: BTH_I0152

Alternate gene names: 83720893

Gene position: 184356-183292 (Counterclockwise)

Preceding gene: 83719400

Following gene: 83721495

Centisome position: 4.84

GC content: 66.29

Gene sequence:

>1065_bases
ATGAGCACGACTTACGCTTACGCGGCAACGAGCGCCACGACGCCGCTCGCGCCGTTCGAATTCCAGCGCCGCGCACTGCG
CGATCTCGATGTGCAGATCGAGATCCTCTACTGCGGCGTCTGCCACTCCGATCTCCACCAGGCCCGCAACGAATGGAAGA
ACACGACTTACCCGGTCGTGCCGGGCCATGAAATCGTCGGCCGCGTGACGGCCGTCGGTCCGCAGGTCACGCGCTTCAAG
ACGGGCGAGCTCGTCGGCGTCGGCTGCCTCGTCGATTCGTGCCGCACGTGCCCGAGCTGCGAGGAAGGGCTCGAGCAGTA
TTGCGAGAACGGTTTCGTCGGCACCTACAACGGCCGCGACCGCGCGACGGGCGACGTCACGTTCGGCGGCTACTCGACGC
AGATCGTCGTCGACGAGGCGTTCGTGCTGCGCGTGCCCGACACGCTCGATCCGGCAGGCGCGGCGCCGCTCCTCTGCGCG
GGCATCACGACGTATTCGCCGCTGCGCCAGTGGGGCGCGGGGCCCGGCAAGAAGGTCGGCGTCGTCGGCCTGGGCGGCCT
GGGCCACATGGGCGTGAAGCTCGCGCGCGCGATGGGCGCGCACGTCGTGCTGTTCACGACGTCGCCGTCGAAGATCGACG
ACGGCAAGCGGCTCGGCGCGCACGAAGTCGTCATTTCGAAGGACGAAGCGCAGATGAATGCGCATCTGAACAGCTTCGAC
TTCATTCTGAACACGGTCGCCGCGCAGCACGATCTGAATCCGTTCCTCCATCTGCTCAAGCGCGACGGCACGATGACGCT
CGTCGGCGCGCCGGAGCACGACCATCCGTCGCCGCAGGTGTTCAACCTGATCTTCAAGCGCCGCCGCCTCGCGGGCTCGC
TGATCGGCGGGATCGCCGAGACGCAGGAAATGCTCGATTTCTGCGCACTGCACGGCATCACGTCGGACATCGAGGTGATT
CCGATGTCGCAGGTCAACGCGGCCTACGAGCGGATGCTCAAGAGCGACGTGAAGTATCGGTTCGTGATCGACATCGGATC
GATCAGGCCGCCGCGCGCCGCGTAA

Upstream 100 bases:

>100_bases
TCCTGCCAACCGGCCGCGTGCTTAGGATTGCTCCCGTGCCGCTGCACCGCCGCATTCCGCGGCCGCGCGCGGCGCACGCC
TTTTCGAGTCAGGAGCCTTC

Downstream 100 bases:

>100_bases
CGGGCGACGCGGGCGACGCGCGGCTGCGCGCCGCAACGCGAGCCGTAAGAACACGGGCCGCGCACGCGGCCCGTTCTTCC
TTCATCGCCCCCCGATCGCC

Product: zinc-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSTTYAYAATSATTPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWKNTTYPVVPGHEIVGRVTAVGPQVTRFK
TGELVGVGCLVDSCRTCPSCEEGLEQYCENGFVGTYNGRDRATGDVTFGGYSTQIVVDEAFVLRVPDTLDPAGAAPLLCA
GITTYSPLRQWGAGPGKKVGVVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIDDGKRLGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCALHGITSDIEVI
PMSQVNAAYERMLKSDVKYRFVIDIGSIRPPRAA

Sequences:

>Translated_354_residues
MSTTYAYAATSATTPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWKNTTYPVVPGHEIVGRVTAVGPQVTRFK
TGELVGVGCLVDSCRTCPSCEEGLEQYCENGFVGTYNGRDRATGDVTFGGYSTQIVVDEAFVLRVPDTLDPAGAAPLLCA
GITTYSPLRQWGAGPGKKVGVVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIDDGKRLGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCALHGITSDIEVI
PMSQVNAAYERMLKSDVKYRFVIDIGSIRPPRAA
>Mature_353_residues
STTYAYAATSATTPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWKNTTYPVVPGHEIVGRVTAVGPQVTRFKT
GELVGVGCLVDSCRTCPSCEEGLEQYCENGFVGTYNGRDRATGDVTFGGYSTQIVVDEAFVLRVPDTLDPAGAAPLLCAG
ITTYSPLRQWGAGPGKKVGVVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIDDGKRLGAHEVVISKDEAQMNAHLNSFDF
ILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCALHGITSDIEVIP
MSQVNAAYERMLKSDVKYRFVIDIGSIRPPRAA

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=346, Percent_Identity=26.0115606936416, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI34577061, Length=354, Percent_Identity=25.9887005649718, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI71743840, Length=363, Percent_Identity=23.9669421487603, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI262073058, Length=363, Percent_Identity=23.9669421487603, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4501929, Length=362, Percent_Identity=25.1381215469613, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI71565152, Length=317, Percent_Identity=22.7129337539432, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786518, Length=340, Percent_Identity=65.8823529411765, Blast_Score=416, Evalue=1e-118,
Organism=Escherichia coli, GI87082401, Length=345, Percent_Identity=35.9420289855072, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87081918, Length=325, Percent_Identity=26.7692307692308, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI226510992, Length=248, Percent_Identity=29.4354838709677, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788073, Length=256, Percent_Identity=25.78125, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788407, Length=272, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790045, Length=273, Percent_Identity=27.1062271062271, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082125, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788075, Length=259, Percent_Identity=25.0965250965251, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=334, Percent_Identity=28.1437125748503, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17562582, Length=350, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17562584, Length=337, Percent_Identity=27.0029673590504, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25146526, Length=329, Percent_Identity=27.0516717325228, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71997431, Length=331, Percent_Identity=26.8882175226586, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=331, Percent_Identity=37.1601208459215, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319949, Length=334, Percent_Identity=35.3293413173653, Blast_Score=172, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6323961, Length=323, Percent_Identity=34.0557275541796, Blast_Score=154, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324486, Length=323, Percent_Identity=32.8173374613003, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319621, Length=322, Percent_Identity=31.055900621118, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323729, Length=322, Percent_Identity=30.1242236024845, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319258, Length=314, Percent_Identity=26.7515923566879, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=292, Percent_Identity=22.9452054794521, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320033, Length=367, Percent_Identity=25.0681198910082, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17737895, Length=373, Percent_Identity=24.6648793565684, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38357; Mature: 38226

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTYAYAATSATTPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWKNTTYPVV
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCCC
PGHEIVGRVTAVGPQVTRFKTGELVGVGCLVDSCRTCPSCEEGLEQYCENGFVGTYNGRD
CCHHHHHHHHHCCCCCEEEECCCEEEEHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCC
RATGDVTFGGYSTQIVVDEAFVLRVPDTLDPAGAAPLLCAGITTYSPLRQWGAGPGKKVG
CCCCEEEECCEEEEEEEECEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCEEE
VVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIDDGKRLGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCALHGITSDIEVIPMSQVNAAYERMLKSDVKYRFVIDIGSIRPPRAA
HHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
STTYAYAATSATTPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWKNTTYPVV
CCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCCC
PGHEIVGRVTAVGPQVTRFKTGELVGVGCLVDSCRTCPSCEEGLEQYCENGFVGTYNGRD
CCHHHHHHHHHCCCCCEEEECCCEEEEHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCC
RATGDVTFGGYSTQIVVDEAFVLRVPDTLDPAGAAPLLCAGITTYSPLRQWGAGPGKKVG
CCCCEEEECCEEEEEEEECEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCEEE
VVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIDDGKRLGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCALHGITSDIEVIPMSQVNAAYERMLKSDVKYRFVIDIGSIRPPRAA
HHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]