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The map label for this gene is panE-2 [H]

Identifier: 83720776

GI number: 83720776

Start: 859834

End: 860856

Strand: Direct

Name: panE-2 [H]

Synonym: BTH_I0749

Alternate gene names: 83720776

Gene position: 859834-860856 (Clockwise)

Preceding gene: 83719227

Following gene: 83721120

Centisome position: 22.57

GC content: 73.41

Gene sequence:

>1023_bases
ATGCCGACGATTTGCGTTTATGGCGCGGGCGCGCTCGGCTGCTATATCGGCGGCCGGCTGATCGCGGGCGGCGCCGACGT
CGCGCTGATCGGCCGCGGGCGGATCGGCGACGCGCTGCGCGCGCACGGGCTCGTGCTGTCCGATTACCGAGGGCGCGACG
CCCGCGTGCCGCCGTCCGCGATCGCGTTCTCGACGGCCGATGCGGCGGCCGCATCCGCGGAACTCGTGCTCGTCACCGTG
AAGTCCGCGGCGACGCCCGCCGTCGGCGCCGCGCTCGCGCGCATCATGCGGCCCGATGCGGTCGTCGTCAGCTTTCAGAA
CGGCGTGCGCAACGCGGATGTGCTGCGCGCCGCGTTGCCCGGCGCGACCGTGCTCGCCGGCATGGTGCCGTTCAACGTGA
TCTCGCGCGGCGAGGGCGGATTCCATCAGGGCACGGCGGGCGAATTGCAGGTCGAGGCCGCGCCCGCGCTGCGGCGCTTC
GCGGAGGCGTTCGAGCGTGCGGGGCTGCCGCTCGTGCCGCGCGCGGACATGCGCGCGGTTCAATGGGCGAAGCTGCTGCT
CAATCTCAACAACGCGATCAATGCGCTCGCGAACCGGCCGCTGAAGGAAGAGCTCGCGGCGCGCAGCTATCGGCGCTGTC
TCGCGCTGGCGCAAATCGAGGCGCTGCGCCTGCTGTCGGCGGCCGGGGTCCGTCCCGCGCGGCTCACGCCGCTGCCGGCC
GCGTGGGTGCCGCGCTTGCTGAGCGTGCCGGACCCGCTGTTCGCGCGGCTCGGGCGGAAGATGCTCGAGATCGATCCGCT
CGCGCGTTCGTCGATGTCGGACGACTTGGCCGCGAAACGGACGACCGAGGTCGAGTGGATCAACGGCGAGATCGTGCGTC
TTGCCGGGCGGCTCGGGCGCGCGGCGCCCGTCAACGCACGCCTTTGCGCGCTGGCTCACGACGCGGAGCGCTCGCACGCG
CGGCCGGCGTGGGGCGGCGACGCGCTGCTCGCCGAATTGCTTGCCGCGGCGCGGGCGGGATAG

Upstream 100 bases:

>100_bases
GTTCTTCGCCGGGCTGCGCGGCGAAGTGCGCGCCGAAGTCGAGCGGCGCGTCGGGCCGGTGCGCGCCGGCACGCGCGGCG
CGCGCGTCTGACTCGCGCCG

Downstream 100 bases:

>100_bases
CCCCGGGGCGGCCGTCGGGTGCTTTGCGCGCATCGGCGGGCAGGCCGTCGATGTGCGCACGCGTGGCCGGGTTGCCGTGC
GGGCGTCGGCGTTGGCGCGG

Product: 2-dehydropantoate 2-reductase

Products: 2-dehydropantoate; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPTICVYGAGALGCYIGGRLIAGGADVALIGRGRIGDALRAHGLVLSDYRGRDARVPPSAIAFSTADAAAASAELVLVTV
KSAATPAVGAALARIMRPDAVVVSFQNGVRNADVLRAALPGATVLAGMVPFNVISRGEGGFHQGTAGELQVEAAPALRRF
AEAFERAGLPLVPRADMRAVQWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQIEALRLLSAAGVRPARLTPLPA
AWVPRLLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRTTEVEWINGEIVRLAGRLGRAAPVNARLCALAHDAERSHA
RPAWGGDALLAELLAAARAG

Sequences:

>Translated_340_residues
MPTICVYGAGALGCYIGGRLIAGGADVALIGRGRIGDALRAHGLVLSDYRGRDARVPPSAIAFSTADAAAASAELVLVTV
KSAATPAVGAALARIMRPDAVVVSFQNGVRNADVLRAALPGATVLAGMVPFNVISRGEGGFHQGTAGELQVEAAPALRRF
AEAFERAGLPLVPRADMRAVQWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQIEALRLLSAAGVRPARLTPLPA
AWVPRLLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRTTEVEWINGEIVRLAGRLGRAAPVNARLCALAHDAERSHA
RPAWGGDALLAELLAAARAG
>Mature_339_residues
PTICVYGAGALGCYIGGRLIAGGADVALIGRGRIGDALRAHGLVLSDYRGRDARVPPSAIAFSTADAAAASAELVLVTVK
SAATPAVGAALARIMRPDAVVVSFQNGVRNADVLRAALPGATVLAGMVPFNVISRGEGGFHQGTAGELQVEAAPALRRFA
EAFERAGLPLVPRADMRAVQWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQIEALRLLSAAGVRPARLTPLPAA
WVPRLLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRTTEVEWINGEIVRLAGRLGRAAPVNARLCALAHDAERSHAR
PAWGGDALLAELLAAARAG

Specific function: Unknown

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: 1.1.1.169

Molecular weight: Translated: 35588; Mature: 35457

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTICVYGAGALGCYIGGRLIAGGADVALIGRGRIGDALRAHGLVLSDYRGRDARVPPSA
CCCEEEECCCHHHHHHCCEEEECCCCEEEEECCCCCHHHHHCCEEEECCCCCCCCCCCHH
IAFSTADAAAASAELVLVTVKSAATPAVGAALARIMRPDAVVVSFQNGVRNADVLRAALP
HEECCCHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCC
GATVLAGMVPFNVISRGEGGFHQGTAGELQVEAAPALRRFAEAFERAGLPLVPRADMRAV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQIEALRLLSAAGVRPARLTPLPA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AWVPRLLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRTTEVEWINGEIVRLAGRLGR
HHHHHHHCCCCHHHHHHCHHHHHCCHHHHHCCCHHHHHHCCCEEEECCCHHHHHHHHCCC
AAPVNARLCALAHDAERSHARPAWGGDALLAELLAAARAG
CCCCCHHHEEHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTICVYGAGALGCYIGGRLIAGGADVALIGRGRIGDALRAHGLVLSDYRGRDARVPPSA
CCEEEECCCHHHHHHCCEEEECCCCEEEEECCCCCHHHHHCCEEEECCCCCCCCCCCHH
IAFSTADAAAASAELVLVTVKSAATPAVGAALARIMRPDAVVVSFQNGVRNADVLRAALP
HEECCCHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCC
GATVLAGMVPFNVISRGEGGFHQGTAGELQVEAAPALRRFAEAFERAGLPLVPRADMRAV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QWAKLLLNLNNAINALANRPLKEELAARSYRRCLALAQIEALRLLSAAGVRPARLTPLPA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AWVPRLLSVPDPLFARLGRKMLEIDPLARSSMSDDLAAKRTTEVEWINGEIVRLAGRLGR
HHHHHHHCCCCHHHHHHCHHHHHCCHHHHHCCCHHHHHHCCCEEEECCCHHHHHHHHCCC
AAPVNARLCALAHDAERSHARPAWGGDALLAELLAAARAG
CCCCCHHHEEHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-pantoate; NADP+

Specific reaction: (R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]