Click here to switch to the map view.

The map label for this gene is yiaY [H]

Identifier: 83720772

GI number: 83720772

Start: 2628295

End: 2630208

Strand: Direct

Name: yiaY [H]

Synonym: BTH_I2335

Alternate gene names: 83720772

Gene position: 2628295-2630208 (Clockwise)

Preceding gene: 83721062

Following gene: 161723139

Centisome position: 69.0

GC content: 67.5

Gene sequence:

>1914_bases
TTGATTTTTACGGTAATAATGCAATTTGGCGTGATTGCGGTAAACGGTCGGATTGAGAATTTTGCTCGGCGAACTTCTCG
GCCAGGTAACGCTGGAGCGCGCGTCGGCCGCGCGAGCGGGCGAAAGCGATGCGGCTCGCCGGCTCCACCGGCTCCACCGG
CTCCACCGGCTCCACCGGGTTCGGCGCCGTCGCGTTCGGCACCAGGCAGGCGAGCGGCCCGTTCGGCATCCGTGATGCTC
GTGCTGTTCCTGCGCAGCGTCATGCGCCACAACGCGCTGAACCTGTACTGCGCCGTGCTCGCGGCGATCACGTCGGCGCG
GAGGTTCGCGTACCGGCGGGCTCCGACCGCGAAGGCGCGGGCCGTGGTGTCCGTCGCGATCCTCCCCGTGTGCCGCCATG
CGGCGATCAGTAGCGCGCGGGCGTTCGCGTCGGCGGCGGGCCGGCGCGGGGATTCGGCGCGCCTGTCCGGCCGGGGCGAG
GACCGGCAAAATCGGACGCCGCACGGCGCAGCGCGGCCCGCGTCGGCGGCGCTCGGCGATGCGCGGCGACGCAAGCGACG
CCGCGCTCGATCGCTCCGAAACGGAGCAGCGTGTGCCGAATTCGAACAGGCGATGCGCGCTATCCAATCGGCCGTTCATG
AAAGCACGGCGTTTTCGCGGGATGGTACGGTTCGTGCGTTTTCGTTTCCCGGACAGACAGGCGATTTCACACGAGACGCA
CTGACACAACCAGGAGACGACATGAGCTATCTGAACATCGCGCAGCGCACCGACAGTTTCTTCATTCCCTGCGTGACCTT
GATCGGCCCGGGCTGCGCGCGAGAGACGGGCGTGCGCGCCAAATCGCTGGGCGCGAAAAAGGCGCTGATCGTGACCGACG
CGGGGCTGCACAAGATGGGGCTGTCCGAGATCGTCGCGGGCCATATCCGCGACGCGGGGCTTCAGGCCGTGATCTTCGCG
GGCGCGGAGCCCAACCCGACCGACGTCAACGTGCACGACGGCGTCGAGCGCTTTCAGCGCGAGGGATGCGACTTCATCGT
ATCGCTCGGCGGTGGGTCGTCGCACGACTGCGCGAAAGGCATCGGGCTCGTCACGGCCGGAGGCGGGCATATCCGCGACT
ATGAAGGGATCGACAAATCGACGGTGCCGATGACGCCGTTGATTTCGATCAACACGACGGCGGGCACGGCCGCGGAGATG
ACGCGATTCTGCATCATCACGAACTCCAGCAATCACGTCAAAATGGCGATCGTCGACTGGCGCTGCACGCCGCTCATCGC
GATCGACGATCCGTGCCTGATGGTGGCGATGCCGCCCGCGCTGACGGCCGCGACAGGCATGGACGCGCTCACCCACGCGG
TGGAGGCCTACGTTTCCACCGCCGCGACGCCGATCACCGACGCCTGCGCCGAAAAGGCCATCGCGCTGATCGGCGAATGG
CTGCCGAAGGCCGTCGCGAACGGCGAATCGATGGAGGCGCGCGCGGCCATGTGCTACGCGCAGTACCTCGCCGGGATGGC
GTTCAACAACGCGTCGCTCGGCTACGTGCATGCGATGGCGCACCAGCTCGGCGGGTTCTACAACCTGCCGCACGGGGTCT
GCAACGCGATCCTGCTGCCGCACGTGTGCGAGTTCAACCTGATTGCCGCGCCCGAACGGTTCGCCACCATCGCGTCGCTC
CTCGGCGTCAATACGGCCGGATCGAGCACCGTCGACGCCGCCCGGGCGGCCATTGCGGCGATCCGCGGGCTCAGCGCCTC
GATCGGCATCCCCGCCGGCCTGGCCGCGCTGGGCGTCAAGGCCGAAGATCACGAGGTGATGGCGAGCAACGCGCAGAAGG
ACGCGTGCATGCTGACCAATCCGCGCAAGGCGACGCTCGCGCAGGTCATCGCGATCTTCGCGGCGGCGATGTGA

Upstream 100 bases:

>100_bases
ATTTTAAAGGCGAATTGAATGATGGAGACCCGGATTTTTATAAAAATTAAAAACCGATTGGTAATTGAATTTGATAAATG
GTGTTTGATGATTTGAAGGA

Downstream 100 bases:

>100_bases
GCGCGATCGTCACGCCGTAGCGCGCGCCGGGGGGGCGGGCGACGCGAGCACGGGGCAGCATTCGCTGGGCGTGACAGGGC
GGAAGTTACGCACGCACGCC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MIFTVIMQFGVIAVNGRIENFARRTSRPGNAGARVGRASGRKRCGSPAPPAPPAPPAPPGSAPSRSAPGRRAARSASVML
VLFLRSVMRHNALNLYCAVLAAITSARRFAYRRAPTAKARAVVSVAILPVCRHAAISSARAFASAAGRRGDSARLSGRGE
DRQNRTPHGAARPASAALGDARRRKRRRARSLRNGAACAEFEQAMRAIQSAVHESTAFSRDGTVRAFSFPGQTGDFTRDA
LTQPGDDMSYLNIAQRTDSFFIPCVTLIGPGCARETGVRAKSLGAKKALIVTDAGLHKMGLSEIVAGHIRDAGLQAVIFA
GAEPNPTDVNVHDGVERFQREGCDFIVSLGGGSSHDCAKGIGLVTAGGGHIRDYEGIDKSTVPMTPLISINTTAGTAAEM
TRFCIITNSSNHVKMAIVDWRCTPLIAIDDPCLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEW
LPKAVANGESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFATIASL
LGVNTAGSSTVDAARAAIAAIRGLSASIGIPAGLAALGVKAEDHEVMASNAQKDACMLTNPRKATLAQVIAIFAAAM

Sequences:

>Translated_637_residues
MIFTVIMQFGVIAVNGRIENFARRTSRPGNAGARVGRASGRKRCGSPAPPAPPAPPAPPGSAPSRSAPGRRAARSASVML
VLFLRSVMRHNALNLYCAVLAAITSARRFAYRRAPTAKARAVVSVAILPVCRHAAISSARAFASAAGRRGDSARLSGRGE
DRQNRTPHGAARPASAALGDARRRKRRRARSLRNGAACAEFEQAMRAIQSAVHESTAFSRDGTVRAFSFPGQTGDFTRDA
LTQPGDDMSYLNIAQRTDSFFIPCVTLIGPGCARETGVRAKSLGAKKALIVTDAGLHKMGLSEIVAGHIRDAGLQAVIFA
GAEPNPTDVNVHDGVERFQREGCDFIVSLGGGSSHDCAKGIGLVTAGGGHIRDYEGIDKSTVPMTPLISINTTAGTAAEM
TRFCIITNSSNHVKMAIVDWRCTPLIAIDDPCLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEW
LPKAVANGESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFATIASL
LGVNTAGSSTVDAARAAIAAIRGLSASIGIPAGLAALGVKAEDHEVMASNAQKDACMLTNPRKATLAQVIAIFAAAM
>Mature_637_residues
MIFTVIMQFGVIAVNGRIENFARRTSRPGNAGARVGRASGRKRCGSPAPPAPPAPPAPPGSAPSRSAPGRRAARSASVML
VLFLRSVMRHNALNLYCAVLAAITSARRFAYRRAPTAKARAVVSVAILPVCRHAAISSARAFASAAGRRGDSARLSGRGE
DRQNRTPHGAARPASAALGDARRRKRRRARSLRNGAACAEFEQAMRAIQSAVHESTAFSRDGTVRAFSFPGQTGDFTRDA
LTQPGDDMSYLNIAQRTDSFFIPCVTLIGPGCARETGVRAKSLGAKKALIVTDAGLHKMGLSEIVAGHIRDAGLQAVIFA
GAEPNPTDVNVHDGVERFQREGCDFIVSLGGGSSHDCAKGIGLVTAGGGHIRDYEGIDKSTVPMTPLISINTTAGTAAEM
TRFCIITNSSNHVKMAIVDWRCTPLIAIDDPCLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEW
LPKAVANGESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFATIASL
LGVNTAGSSTVDAARAAIAAIRGLSASIGIPAGLAALGVKAEDHEVMASNAQKDACMLTNPRKATLAQVIAIFAAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=389, Percent_Identity=28.2776349614396, Blast_Score=135, Evalue=2e-31,
Organism=Escherichia coli, GI48994951, Length=379, Percent_Identity=57.2559366754617, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1789163, Length=360, Percent_Identity=42.2222222222222, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI87082107, Length=399, Percent_Identity=36.5914786967419, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1787493, Length=381, Percent_Identity=32.2834645669291, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789386, Length=359, Percent_Identity=25.6267409470752, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=399, Percent_Identity=25.31328320802, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=50.9234828496042, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=26.0975609756098, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 66542; Mature: 66542

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFTVIMQFGVIAVNGRIENFARRTSRPGNAGARVGRASGRKRCGSPAPPAPPAPPAPPG
CHHHEEEHHCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCC
SAPSRSAPGRRAARSASVMLVLFLRSVMRHNALNLYCAVLAAITSARRFAYRRAPTAKAR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AVVSVAILPVCRHAAISSARAFASAAGRRGDSARLSGRGEDRQNRTPHGAARPASAALGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ARRRKRRRARSLRNGAACAEFEQAMRAIQSAVHESTAFSRDGTVRAFSFPGQTGDFTRDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
LTQPGDDMSYLNIAQRTDSFFIPCVTLIGPGCARETGVRAKSLGAKKALIVTDAGLHKMG
HCCCCCCHHHHHHHHHCCCHHEHHHHHHCCCCCHHHCCCHHHCCCCEEEEEECCCHHHHC
LSEIVAGHIRDAGLQAVIFAGAEPNPTDVNVHDGVERFQREGCDFIVSLGGGSSHDCAKG
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHCC
IGLVTAGGGHIRDYEGIDKSTVPMTPLISINTTAGTAAEMTRFCIITNSSNHVKMAIVDW
CEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHEEEEEEECCCCEEEEEEEEC
RCTPLIAIDDPCLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEW
CCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LPKAVANGESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLP
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
HVCEFNLIAAPERFATIASLLGVNTAGSSTVDAARAAIAAIRGLSASIGIPAGLAALGVK
HHHCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
AEDHEVMASNAQKDACMLTNPRKATLAQVIAIFAAAM
CCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFTVIMQFGVIAVNGRIENFARRTSRPGNAGARVGRASGRKRCGSPAPPAPPAPPAPPG
CHHHEEEHHCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCC
SAPSRSAPGRRAARSASVMLVLFLRSVMRHNALNLYCAVLAAITSARRFAYRRAPTAKAR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AVVSVAILPVCRHAAISSARAFASAAGRRGDSARLSGRGEDRQNRTPHGAARPASAALGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ARRRKRRRARSLRNGAACAEFEQAMRAIQSAVHESTAFSRDGTVRAFSFPGQTGDFTRDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
LTQPGDDMSYLNIAQRTDSFFIPCVTLIGPGCARETGVRAKSLGAKKALIVTDAGLHKMG
HCCCCCCHHHHHHHHHCCCHHEHHHHHHCCCCCHHHCCCHHHCCCCEEEEEECCCHHHHC
LSEIVAGHIRDAGLQAVIFAGAEPNPTDVNVHDGVERFQREGCDFIVSLGGGSSHDCAKG
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHCC
IGLVTAGGGHIRDYEGIDKSTVPMTPLISINTTAGTAAEMTRFCIITNSSNHVKMAIVDW
CEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHEEEEEEECCCCEEEEEEEEC
RCTPLIAIDDPCLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEW
CCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LPKAVANGESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLP
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
HVCEFNLIAAPERFATIASLLGVNTAGSSTVDAARAAIAAIRGLSASIGIPAGLAALGVK
HHHCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
AEDHEVMASNAQKDACMLTNPRKATLAQVIAIFAAAM
CCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]