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The map label for this gene is tktA [C]

Identifier: 83720625

GI number: 83720625

Start: 2224095

End: 2224919

Strand: Direct

Name: tktA [C]

Synonym: BTH_I1962

Alternate gene names: 83720625

Gene position: 2224095-2224919 (Clockwise)

Preceding gene: 83719274

Following gene: 83719464

Centisome position: 58.39

GC content: 69.33

Gene sequence:

>825_bases
ATGACGATGAATCTCGATCATCAGGTGCTGGAAAATCGAAAGCGGGTGCTGAAGATGCTGCACGGCGTCGACGGCGGGCA
TTTTGGCGGCGCGATGAGCGTGCTCGACACGCTCGTCGTGCTGTATCACCGCGTGCTGCGGCGCGATGCCGGGCGCAGGG
CCGAGGGGCGCGGCGATCGGCTGATCCTCTCGAAGGGGCATGCGTCGGTCGCGCTGTACGCGGTGCTCGCGTCGATCGGC
GAGCTGCCGGAGGCGGAGCTCGCCACATACGGCAAGGGCGGCGGGCGTCTGCCGTGCCATCCCGACATGACGCTGCTCGA
CGCGGTCGATTTCTCGACGGGCTCGCTTGGACAGGGGCTGTCCGTCGGGCTCGGAATGGCTTTCGCGTTGCGCGGCACCG
GCGCGCGCGTGTGGGTCGTGCTCGGCGACGGCGAATGCCAGGAAGGCCAGGTGTGGGAGGCGGCTCAGTTCGCGTCGCGC
TACGGCGTCGACAACCTGCATGCGATCGTCGATCTGAACGGCTTTCAGGAGATGGGCTGGCGCGGCGTCGACGGCGTCCA
GCCCGATCCGCTGCCCGACGCGGCGCGCAAATGGGAGGCGTTCGGCTGGCACGTGCGCGAAGTGGCGGGGCACGACCTCG
CGCAACTCGAGGCCGCGATGCACGGGATGACCGCGCGGCGGGGACGGCCGAGCGTGCTCCTCGCGACGACCGTGAAGGGG
CGCGGCATTCCCGCGTTCGAATGCGATCCCGGGCTGTCGCATTGCACGTCGCTCACCGACGATCAGTTCAGGCACGCGGT
GGCCGTCGCGGAGGGCGTGGCATGA

Upstream 100 bases:

>100_bases
CTCGCCGCGTTCGGCGCGCGCTGGCGCGAGATCCGGCCGGAGCGGCTGTTGCGCGAGCATGGCTTGTCGCGGCTGCGCTG
AACTCTTGTTTCGAACAGGA

Downstream 100 bases:

>100_bases
GGCCCGCCGCCCATTGCGTGCAGGCGCTCGTCGAACGCGCCGCGCATGATCGCCGGATCTGGGTGCTGGACGGCGATCTC
GCCGATTCCTACGGCGCGGA

Product: transketolase, N-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTMNLDHQVLENRKRVLKMLHGVDGGHFGGAMSVLDTLVVLYHRVLRRDAGRRAEGRGDRLILSKGHASVALYAVLASIG
ELPEAELATYGKGGGRLPCHPDMTLLDAVDFSTGSLGQGLSVGLGMAFALRGTGARVWVVLGDGECQEGQVWEAAQFASR
YGVDNLHAIVDLNGFQEMGWRGVDGVQPDPLPDAARKWEAFGWHVREVAGHDLAQLEAAMHGMTARRGRPSVLLATTVKG
RGIPAFECDPGLSHCTSLTDDQFRHAVAVAEGVA

Sequences:

>Translated_274_residues
MTMNLDHQVLENRKRVLKMLHGVDGGHFGGAMSVLDTLVVLYHRVLRRDAGRRAEGRGDRLILSKGHASVALYAVLASIG
ELPEAELATYGKGGGRLPCHPDMTLLDAVDFSTGSLGQGLSVGLGMAFALRGTGARVWVVLGDGECQEGQVWEAAQFASR
YGVDNLHAIVDLNGFQEMGWRGVDGVQPDPLPDAARKWEAFGWHVREVAGHDLAQLEAAMHGMTARRGRPSVLLATTVKG
RGIPAFECDPGLSHCTSLTDDQFRHAVAVAEGVA
>Mature_273_residues
TMNLDHQVLENRKRVLKMLHGVDGGHFGGAMSVLDTLVVLYHRVLRRDAGRRAEGRGDRLILSKGHASVALYAVLASIGE
LPEAELATYGKGGGRLPCHPDMTLLDAVDFSTGSLGQGLSVGLGMAFALRGTGARVWVVLGDGECQEGQVWEAAQFASRY
GVDNLHAIVDLNGFQEMGWRGVDGVQPDPLPDAARKWEAFGWHVREVAGHDLAQLEAAMHGMTARRGRPSVLLATTVKGR
GIPAFECDPGLSHCTSLTDDQFRHAVAVAEGVA

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=245, Percent_Identity=35.9183673469388, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI205277463, Length=247, Percent_Identity=37.6518218623482, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4507521, Length=247, Percent_Identity=37.6518218623482, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI225637463, Length=147, Percent_Identity=39.4557823129252, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225637459, Length=147, Percent_Identity=39.4557823129252, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225637461, Length=147, Percent_Identity=39.4557823129252, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI48994911, Length=251, Percent_Identity=31.8725099601594, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788808, Length=251, Percent_Identity=32.2709163346614, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17539652, Length=243, Percent_Identity=35.8024691358025, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6325331, Length=234, Percent_Identity=31.6239316239316, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319593, Length=242, Percent_Identity=25.6198347107438, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45551847, Length=226, Percent_Identity=37.1681415929204, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45550715, Length=226, Percent_Identity=37.1681415929204, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24666278, Length=257, Percent_Identity=35.0194552529183, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24645119, Length=213, Percent_Identity=38.0281690140845, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 29353; Mature: 29222

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNLDHQVLENRKRVLKMLHGVDGGHFGGAMSVLDTLVVLYHRVLRRDAGRRAEGRGDR
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
LILSKGHASVALYAVLASIGELPEAELATYGKGGGRLPCHPDMTLLDAVDFSTGSLGQGL
EEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCH
SVGLGMAFALRGTGARVWVVLGDGECQEGQVWEAAQFASRYGVDNLHAIVDLNGFQEMGW
HHHHHHHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHCCC
RGVDGVQPDPLPDAARKWEAFGWHVREVAGHDLAQLEAAMHGMTARRGRPSVLLATTVKG
CCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECC
RGIPAFECDPGLSHCTSLTDDQFRHAVAVAEGVA
CCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TMNLDHQVLENRKRVLKMLHGVDGGHFGGAMSVLDTLVVLYHRVLRRDAGRRAEGRGDR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
LILSKGHASVALYAVLASIGELPEAELATYGKGGGRLPCHPDMTLLDAVDFSTGSLGQGL
EEEECCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCH
SVGLGMAFALRGTGARVWVVLGDGECQEGQVWEAAQFASRYGVDNLHAIVDLNGFQEMGW
HHHHHHHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHCCC
RGVDGVQPDPLPDAARKWEAFGWHVREVAGHDLAQLEAAMHGMTARRGRPSVLLATTVKG
CCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECC
RGIPAFECDPGLSHCTSLTDDQFRHAVAVAEGVA
CCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]