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The map label for this gene is yjcE [H]

Identifier: 83720593

GI number: 83720593

Start: 364390

End: 366354

Strand: Reverse

Name: yjcE [H]

Synonym: BTH_I0329

Alternate gene names: 83720593

Gene position: 366354-364390 (Counterclockwise)

Preceding gene: 83718411

Following gene: 83720168

Centisome position: 9.62

GC content: 69.01

Gene sequence:

>1965_bases
ATGACGAAAACGTCGGCAGGCGAAACGTGCGACTCGCGGGTTTTCATCGGTGGTCCTCGGTTGTTCGATAGTAGTTGTCG
GCAAGCATCAAGCAAGCTCCGTGCTCACTCGCGCGGCGCCGCGCCCCGCCGCCCGCGCCCCGGCACGGACGCGGCGCGCG
CGTCGCACCACGCATGCATGCCGGCGGGGATTGCGCGCACCATCACGGTGCACCCGCGCTCGCGCGTCGCTTCACGCCGC
CCATCTCGCGCGCACGCTACACTGCGTACCGTCGTTTCATCCCCGTTTCGATCATCGATGGCAATCGTCTTCACTGTTTT
GATCCTGTTGCTCGCGGTCGCGCTGTCCGGCATCGCGACGCGCGTGCTGCCGCTACGCCTGCCGTTGCCGCTGATGCAGA
TCGCGATCGGCGCGGCGCTCGCGTGGCCGAAGTTCAACCTGCACGTCACGTTCGATCCCGAAATCTTCATGCTGCTGTTC
ATTCCGCCGCTGCTGTTCGCGGACGGCTGGCGCATTCCGAAGCGCGAGCTGTATCTGCAGCGGCGCGCGATCCTGATGCT
CGCGTTCGGCCTCGTCTTCATGACGGTACTCGCGGTCGGCTACTTCGCGCATTGGTTGATTCCCGGCCTGCCGCTGCCCA
TCGCGTTCGCGCTCGCCGCGGTGCTGTCGCCCACCGATGCGGTCGCGCTCGCCGGCATCGCCGGCAAGGGCCGCATCCCG
CCGCAACTGATGCACATCCTCGAAGGCGAGGCGCTGATGAACGACGCATCGGGCCTCGTCGCGCTCAAGTTCGCGATCGC
GGCCGCGCTGACCGGCGTGTTTTCGCTGCGCGACGCGTCGATCAGCTTCGTGATCGTCGCATCGGGCGGCCTGGCGACGG
GCGCGGCCCTCTCATGGCTGTTCAGCGCGCTGTCGACGCGCTTTTTGAACGCCGCGCAGGAAGGCGATCCGGCCCCCGGC
ATCGTGATGACGCTGCTCGTGCCGTTCGCGTCGTATCTGATCGCCGAGCACCTCGGACTGTCAGGAATCCTGTCGGCCGT
CGCGTCCGGGATGATGATGAACTACACGAGCTTCTCGAAGAGCAGCACGGTCGCCGCGCGGGTGCGCGCGGAAAGCACGT
GGGCGATGATCGAATTCGTGTTCAACGGGATGGTGTTCATCATGCTCGGGTTGCAGTTGCCGCACATCATCGGCCGCGCG
CTCGTCGACGCGCACCATACGAGCGATGCGCTCGTCGGCGCGATGATCGGTTATGTCGCCGCGATGCTCGCCGCGCTCTA
CGCGATCCGCTTCGCGTGGGTATGGCTGCTGCGCTGGATCGCGAGCCGCCGCGCGGCGAAGCAGGGGCTCGCCGGCACGA
TGGCGGGCCTGCGCACGATCGCCGTGATGACGGTGGGCGGCGTGCGCGGCGCGATCACGCTCGCCGGCGTGCTGTCGGTT
CCGGTCGCGCTCGGCGACGGCACGCCGCTCGCCGGCCGCGACACCGCGATCTTCGTCGCGTCGGGCGTGATTCTCGGCTC
GCTCGTCGTCGCGGTGATCGCGCTGCCGCTGCTGCTGCGCGGCGTGCGCCCGATGCGCAATCCGCACGCGGAGGAAGAGC
GCGCCGCGCGCGCGGCGGCCGCGCAGGCGGCGATCCGCGCGGTGGACGCGGCGCACGACGCGCTCGCCGTCGATCTCGAC
GAAACGGCCGCCGCGCGCTGCGCGGACGTGACCGCGCGCGTGATGGACCTGTACCGCCGCCGGCTCGCGGGCCTCGCCGC
GGACGGCGCGACGCCGCGCGAGGAGGCGCGGCAAACGGAGAAGATAGAGCTGGCGCTGAAGATCGCCGCGATCCGCGCGG
AGCGCGCGGTGCTCTACCGGCTGCGCGGCGAGCAGAAGATCAACGACGAGACGCTCGCGAAGCTGATGCGCGAAATCGAT
TTGTCGGAGACGGCGCTGTCGACGCGCAAGAAGGGAATCGTCTGA

Upstream 100 bases:

>100_bases
CGACGCGCTCGAGACCGGACGTCATCTCCGCCTCGAAGCGATACGGCGACGCGGCGACGGGACGTTCCTGCTGGGCGATG
GTCATGAAGCGGCCCTCCTG

Downstream 100 bases:

>100_bases
CGCGGCGCGCGCCGCTGCATCGGACGACTAACGAACCGCGGCGAAGCGGCGAAGCGGCGAAGCGGCGAAGCGGCGAAGCG
GCGAAGCGGCGAAGCGGCGA

Product: Na+:H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 653

Protein sequence:

>654_residues
MTKTSAGETCDSRVFIGGPRLFDSSCRQASSKLRAHSRGAAPRRPRPGTDAARASHHACMPAGIARTITVHPRSRVASRR
PSRAHATLRTVVSSPFRSSMAIVFTVLILLLAVALSGIATRVLPLRLPLPLMQIAIGAALAWPKFNLHVTFDPEIFMLLF
IPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIP
PQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDASISFVIVASGGLATGAALSWLFSALSTRFLNAAQEGDPAPG
IVMTLLVPFASYLIAEHLGLSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRA
LVDAHHTSDALVGAMIGYVAAMLAALYAIRFAWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSV
PVALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLD
ETAAARCADVTARVMDLYRRRLAGLAADGATPREEARQTEKIELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREID
LSETALSTRKKGIV

Sequences:

>Translated_654_residues
MTKTSAGETCDSRVFIGGPRLFDSSCRQASSKLRAHSRGAAPRRPRPGTDAARASHHACMPAGIARTITVHPRSRVASRR
PSRAHATLRTVVSSPFRSSMAIVFTVLILLLAVALSGIATRVLPLRLPLPLMQIAIGAALAWPKFNLHVTFDPEIFMLLF
IPPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIP
PQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDASISFVIVASGGLATGAALSWLFSALSTRFLNAAQEGDPAPG
IVMTLLVPFASYLIAEHLGLSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRA
LVDAHHTSDALVGAMIGYVAAMLAALYAIRFAWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSV
PVALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLD
ETAAARCADVTARVMDLYRRRLAGLAADGATPREEARQTEKIELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREID
LSETALSTRKKGIV
>Mature_653_residues
TKTSAGETCDSRVFIGGPRLFDSSCRQASSKLRAHSRGAAPRRPRPGTDAARASHHACMPAGIARTITVHPRSRVASRRP
SRAHATLRTVVSSPFRSSMAIVFTVLILLLAVALSGIATRVLPLRLPLPLMQIAIGAALAWPKFNLHVTFDPEIFMLLFI
PPLLFADGWRIPKRELYLQRRAILMLAFGLVFMTVLAVGYFAHWLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIPP
QLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDASISFVIVASGGLATGAALSWLFSALSTRFLNAAQEGDPAPGI
VMTLLVPFASYLIAEHLGLSGILSAVASGMMMNYTSFSKSSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRAL
VDAHHTSDALVGAMIGYVAAMLAALYAIRFAWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSVP
VALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAAAQAAIRAVDAAHDALAVDLDE
TAAARCADVTARVMDLYRRRLAGLAADGATPREEARQTEKIELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREIDL
SETALSTRKKGIV

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=352, Percent_Identity=23.0113636363636, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI5454070, Length=286, Percent_Identity=23.4265734265734, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI110227626, Length=262, Percent_Identity=24.8091603053435, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI294997330, Length=267, Percent_Identity=23.9700374531835, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI41872703, Length=322, Percent_Identity=25.1552795031056, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI14211919, Length=399, Percent_Identity=21.3032581453634, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI148727259, Length=312, Percent_Identity=26.2820512820513, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1790501, Length=555, Percent_Identity=48.8288288288288, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI71980847, Length=384, Percent_Identity=25.2604166666667, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=459, Percent_Identity=24.400871459695, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71999819, Length=459, Percent_Identity=24.400871459695, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=425, Percent_Identity=24.7058823529412, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71987535, Length=459, Percent_Identity=23.7472766884532, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71987537, Length=459, Percent_Identity=23.7472766884532, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25150332, Length=367, Percent_Identity=22.6158038147139, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71990932, Length=384, Percent_Identity=24.4791666666667, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71990924, Length=404, Percent_Identity=24.009900990099, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992107, Length=261, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992101, Length=261, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=261, Percent_Identity=24.904214559387, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221473212, Length=458, Percent_Identity=22.2707423580786, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364513, Length=290, Percent_Identity=24.8275862068966, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221473222, Length=290, Percent_Identity=24.8275862068966, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221473215, Length=290, Percent_Identity=24.8275862068966, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281360447, Length=320, Percent_Identity=24.375, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221510738, Length=389, Percent_Identity=24.6786632390745, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221510734, Length=389, Percent_Identity=24.6786632390745, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221510732, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221510736, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221510740, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585580, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585578, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 69541; Mature: 69410

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSAGETCDSRVFIGGPRLFDSSCRQASSKLRAHSRGAAPRRPRPGTDAARASHHACM
CCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCC
PAGIARTITVHPRSRVASRRPSRAHATLRTVVSSPFRSSMAIVFTVLILLLAVALSGIAT
CCCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVLPLRLPLPLMQIAIGAALAWPKFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQ
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHH
RRAILMLAFGLVFMTVLAVGYFAHWLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
PQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDASISFVIVASGGLATGAALSWL
HHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHH
FSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLGLSGILSAVASGMMMNYTSFSK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
SSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGAMIGYVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AMLAALYAIRFAWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
PVALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAA
CEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AQAAIRAVDAAHDALAVDLDETAAARCADVTARVMDLYRRRLAGLAADGATPREEARQTE
HHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KIELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREIDLSETALSTRKKGIV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TKTSAGETCDSRVFIGGPRLFDSSCRQASSKLRAHSRGAAPRRPRPGTDAARASHHACM
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCC
PAGIARTITVHPRSRVASRRPSRAHATLRTVVSSPFRSSMAIVFTVLILLLAVALSGIAT
CCCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RVLPLRLPLPLMQIAIGAALAWPKFNLHVTFDPEIFMLLFIPPLLFADGWRIPKRELYLQ
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHH
RRAILMLAFGLVFMTVLAVGYFAHWLIPGLPLPIAFALAAVLSPTDAVALAGIAGKGRIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
PQLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDASISFVIVASGGLATGAALSWL
HHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHH
FSALSTRFLNAAQEGDPAPGIVMTLLVPFASYLIAEHLGLSGILSAVASGMMMNYTSFSK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
SSTVAARVRAESTWAMIEFVFNGMVFIMLGLQLPHIIGRALVDAHHTSDALVGAMIGYVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AMLAALYAIRFAWVWLLRWIASRRAAKQGLAGTMAGLRTIAVMTVGGVRGAITLAGVLSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
PVALGDGTPLAGRDTAIFVASGVILGSLVVAVIALPLLLRGVRPMRNPHAEEERAARAAA
CEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AQAAIRAVDAAHDALAVDLDETAAARCADVTARVMDLYRRRLAGLAADGATPREEARQTE
HHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KIELALKIAAIRAERAVLYRLRGEQKINDETLAKLMREIDLSETALSTRKKGIV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]