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The map label for this gene is zraR [H]

Identifier: 83720565

GI number: 83720565

Start: 1057567

End: 1058997

Strand: Direct

Name: zraR [H]

Synonym: BTH_I0936

Alternate gene names: 83720565

Gene position: 1057567-1058997 (Clockwise)

Preceding gene: 83720238

Following gene: 83719129

Centisome position: 27.76

GC content: 64.15

Gene sequence:

>1431_bases
ATGCATGACGTCCGCACTCCTCCTGATCACGCGTTGCCCGACGACACGCCGCGCCTTGCCGTCGTGAGGTCTGATGCGGA
CGCCGATGAACTCGTTTTGCGATCTCTCGTCTACGTGTCGCGCAATCCGGATGACGCGCTGGTCGAGCACTTGCGCGCGC
GCCGGTGGAGCGTGCACGTCGAACGCTGCGCGAATGACGCGGCGCGCCGCCTGAAACTCAACCGGCCGCAAGTCGGCATC
GTCGATTTCGAAGGTATTGCTTCACGCGAGTTGCCGACGCTCGAGACCCTGTTGGCGCATCAGCAGGTCGGCTGGATCGC
CATTGCCGGCGACAACCGGTTGAACGATGCGAAGATCCGGCGGCTGATCCGCCAGTTCTGCTTCGATTACGCGAAGGAAT
TGCCGCCTGAAGCGCTTTTCGACTATCTCGTCGACCATGCATACGGGATGGTCGCGCTCTGCGATCTCGACAGCGACGCT
TGGCTTCCACAGGCGGAAAGCAACGAGATGGTGGGCGCGTGCGACGCGATGCAGCAACTGTTCCGGACGATTCGCAAAAT
CGCGCTGACCGACGCGACGGTGTTCATTTCCGGCGAATCCGGCACAGGCAAGGAACTCAGCGCGCTTGCGATCCATGAGC
GTTCGGCGCGCGGGAAGGCGCCGTTCGTCGCGATCAATTGCGGCGCCATCCCGCCCAATCTGCTGCAATCCGAATTGTTC
GGCTACGAGCGCGGCGCATTCACCGGCGCGAATCAACGCAAGATCGGCCGGGTCGAGGCGGCGGCGGGCGGGACATTGTT
CCTCGACGAGATCGGCGACATGCCCCTCGAAAGCCAGGCGAGCATGCTGCGTTTCCTGCAGGAAGGCAAGATCGAGCGTC
TCGGCGGGCGTGAGCCCATTCCCGTCGACGTACGGATCGTCTCCGCGACCCACGTCGACATCGAGGCGGCAATACGGGAA
GGCCGATTCCGCGAAGACCTGTATCATCGGCTGTGCGTCCTGAGGCTCGACATCCCCGCGCTGCGGGCGCGCGGCAAGGA
CATCGAGATCCTCGCGCATCGCGCGCTGCACAAGTTCGGAGGGGACAGCGCGCGCCAGATTCGCGGCTTTACGTCATGCG
CGATCGAAGCGATGTATCGCTACTCGTGGCCGGGCAACGTGCGCGAACTGATCAACCGGATCCGCCGCGCAATCGTGCTG
TCTGACAGTTGCCTGATATCGGCCGCCGATCTCGACCTCGCGCAGTTCGTGACGCAACACGCGACGACGCTTGCGCAGGC
GCGCGATATCGCGGAACACCGCGCGATAGAGGCATCGTTGCTGCGGCATCGCGGCCACCTGGCGGAAGCGGCGACCGAAC
TCGGCGTGTCTTGCACGGCGCTCAGCCGGCTGATGGCGAAGTACGGGTTGCCCGCGTGTTCGGTCGAGTAG

Upstream 100 bases:

>100_bases
TGCATCCGTCGCGGTCGGCCTGACGCCCGACGCGCCAAATTTCGTCGTCGGCGTGCGTTTCCCGTACACGTTCTGACGCA
CTATTCCGCGAGAACCCATC

Downstream 100 bases:

>100_bases
TCTCGGAGTGAATTCGAAGCCCAGGAGGCCGGGAATCCGATTTCGTGTCGGATAGGCAGAGCGGTGCGAATGGCAAGCCG
GCCGCTCGATTCGATCGAAC

Product: sigma-54 dependent DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MHDVRTPPDHALPDDTPRLAVVRSDADADELVLRSLVYVSRNPDDALVEHLRARRWSVHVERCANDAARRLKLNRPQVGI
VDFEGIASRELPTLETLLAHQQVGWIAIAGDNRLNDAKIRRLIRQFCFDYAKELPPEALFDYLVDHAYGMVALCDLDSDA
WLPQAESNEMVGACDAMQQLFRTIRKIALTDATVFISGESGTGKELSALAIHERSARGKAPFVAINCGAIPPNLLQSELF
GYERGAFTGANQRKIGRVEAAAGGTLFLDEIGDMPLESQASMLRFLQEGKIERLGGREPIPVDVRIVSATHVDIEAAIRE
GRFREDLYHRLCVLRLDIPALRARGKDIEILAHRALHKFGGDSARQIRGFTSCAIEAMYRYSWPGNVRELINRIRRAIVL
SDSCLISAADLDLAQFVTQHATTLAQARDIAEHRAIEASLLRHRGHLAEAATELGVSCTALSRLMAKYGLPACSVE

Sequences:

>Translated_476_residues
MHDVRTPPDHALPDDTPRLAVVRSDADADELVLRSLVYVSRNPDDALVEHLRARRWSVHVERCANDAARRLKLNRPQVGI
VDFEGIASRELPTLETLLAHQQVGWIAIAGDNRLNDAKIRRLIRQFCFDYAKELPPEALFDYLVDHAYGMVALCDLDSDA
WLPQAESNEMVGACDAMQQLFRTIRKIALTDATVFISGESGTGKELSALAIHERSARGKAPFVAINCGAIPPNLLQSELF
GYERGAFTGANQRKIGRVEAAAGGTLFLDEIGDMPLESQASMLRFLQEGKIERLGGREPIPVDVRIVSATHVDIEAAIRE
GRFREDLYHRLCVLRLDIPALRARGKDIEILAHRALHKFGGDSARQIRGFTSCAIEAMYRYSWPGNVRELINRIRRAIVL
SDSCLISAADLDLAQFVTQHATTLAQARDIAEHRAIEASLLRHRGHLAEAATELGVSCTALSRLMAKYGLPACSVE
>Mature_476_residues
MHDVRTPPDHALPDDTPRLAVVRSDADADELVLRSLVYVSRNPDDALVEHLRARRWSVHVERCANDAARRLKLNRPQVGI
VDFEGIASRELPTLETLLAHQQVGWIAIAGDNRLNDAKIRRLIRQFCFDYAKELPPEALFDYLVDHAYGMVALCDLDSDA
WLPQAESNEMVGACDAMQQLFRTIRKIALTDATVFISGESGTGKELSALAIHERSARGKAPFVAINCGAIPPNLLQSELF
GYERGAFTGANQRKIGRVEAAAGGTLFLDEIGDMPLESQASMLRFLQEGKIERLGGREPIPVDVRIVSATHVDIEAAIRE
GRFREDLYHRLCVLRLDIPALRARGKDIEILAHRALHKFGGDSARQIRGFTSCAIEAMYRYSWPGNVRELINRIRRAIVL
SDSCLISAADLDLAQFVTQHATTLAQARDIAEHRAIEASLLRHRGHLAEAATELGVSCTALSRLMAKYGLPACSVE

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=314, Percent_Identity=44.9044585987261, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1788550, Length=311, Percent_Identity=44.3729903536978, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=42.1686746987952, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1788905, Length=297, Percent_Identity=44.4444444444444, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=41.25, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI87082117, Length=233, Percent_Identity=48.4978540772532, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1789087, Length=399, Percent_Identity=36.5914786967419, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=313, Percent_Identity=41.5335463258786, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082152, Length=407, Percent_Identity=34.3980343980344, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87081872, Length=334, Percent_Identity=35.3293413173653, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=34.8242811501597, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI87081858, Length=295, Percent_Identity=31.1864406779661, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=32.3886639676113, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52732; Mature: 52732

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDVRTPPDHALPDDTPRLAVVRSDADADELVLRSLVYVSRNPDDALVEHLRARRWSVHV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ERCANDAARRLKLNRPQVGIVDFEGIASRELPTLETLLAHQQVGWIAIAGDNRLNDAKIR
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHH
RLIRQFCFDYAKELPPEALFDYLVDHAYGMVALCDLDSDAWLPQAESNEMVGACDAMQQL
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
FRTIRKIALTDATVFISGESGTGKELSALAIHERSARGKAPFVAINCGAIPPNLLQSELF
HHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GYERGAFTGANQRKIGRVEAAAGGTLFLDEIGDMPLESQASMLRFLQEGKIERLGGREPI
CCCCCCCCCCCCCCCCCEEECCCCEEEHHHHCCCCCHHHHHHHHHHHCCCHHHCCCCCCC
PVDVRIVSATHVDIEAAIREGRFREDLYHRLCVLRLDIPALRARGKDIEILAHRALHKFG
CEEEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHC
GDSARQIRGFTSCAIEAMYRYSWPGNVRELINRIRRAIVLSDSCLISAADLDLAQFVTQH
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
ATTLAQARDIAEHRAIEASLLRHRGHLAEAATELGVSCTALSRLMAKYGLPACSVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHDVRTPPDHALPDDTPRLAVVRSDADADELVLRSLVYVSRNPDDALVEHLRARRWSVHV
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ERCANDAARRLKLNRPQVGIVDFEGIASRELPTLETLLAHQQVGWIAIAGDNRLNDAKIR
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHH
RLIRQFCFDYAKELPPEALFDYLVDHAYGMVALCDLDSDAWLPQAESNEMVGACDAMQQL
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
FRTIRKIALTDATVFISGESGTGKELSALAIHERSARGKAPFVAINCGAIPPNLLQSELF
HHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GYERGAFTGANQRKIGRVEAAAGGTLFLDEIGDMPLESQASMLRFLQEGKIERLGGREPI
CCCCCCCCCCCCCCCCCEEECCCCEEEHHHHCCCCCHHHHHHHHHHHCCCHHHCCCCCCC
PVDVRIVSATHVDIEAAIREGRFREDLYHRLCVLRLDIPALRARGKDIEILAHRALHKFG
CEEEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHC
GDSARQIRGFTSCAIEAMYRYSWPGNVRELINRIRRAIVLSDSCLISAADLDLAQFVTQH
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
ATTLAQARDIAEHRAIEASLLRHRGHLAEAATELGVSCTALSRLMAKYGLPACSVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]