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The map label for this gene is ychM [C]

Identifier: 83720512

GI number: 83720512

Start: 2879849

End: 2881561

Strand: Reverse

Name: ychM [C]

Synonym: BTH_I2524

Alternate gene names: 83720512

Gene position: 2881561-2879849 (Counterclockwise)

Preceding gene: 83719811

Following gene: 83719352

Centisome position: 75.65

GC content: 69.76

Gene sequence:

>1713_bases
ATGGATCTTCGCTCGAAACACATCGACGCGCCGCCGCAGCAGGCCGCGCATTTCGCATCGCTCGACAAGCCGCCCGCGCC
GCGCGGGCGGCGCGCGGTGCTCGACGCGCTCGCGGGGCTGTCGATCGCGGGCCTGCTGATACCGGAGGCGGTCGCGTACG
CGGGGCTCGCGAGCCTGCCGCCGCAGGCGGGGCTCATCGCGCTCGTCGTTGGGCTCGTCGTCTACGCGATCGCGGGCAGC
AGCCGCTTCGCGATCGTGTCGGCGACGTCGTCGTCGGCCGTCGTGCTCGCGGCCACCGTGATGTCCGAGGCCGGGCCGGG
CGCCGCCGCGCAACTGATGCTCGCCGCCGCGCTCGTCGCGACGACGGGCATCCTGTTCGTGTTCGCGGGCGCCGCGCGTC
TGGGCGGCATGTCGGATTTCATCGCGCGGCCGGTGCTGCGTGGGTTCACATTCGGTCTTGCGCTCACGATCGTGATCAAG
CAGGTGCCGAAGGTGCTCGACGTGCGGATTCATCACGGCGATACGTTGCGCGTCGTGCTCGACCTGCTGCTCGGCATACC
GGACTGCAACGTCTACAGCACGGCGCTCGGCGCGACGGCGCTTGCGATCCTGTTCACGCTCGGCAGGCGCACGCGCGTGC
CGGCGACGCTCGTCGTGATCGTGCTCGGCATCGCGGCGGGCTACTGGATCGACTGGCATCGTTACGGCATCGCCGTCGTC
GGCGCGATCGATCTGCAGAACCTCGCGTTCGGCATGCCGGTGCTCGGCCGCTCCGGCTGGATGCAGACAGCCGAGTTCGG
CTTCGCGCTGATGCTGATCCTGTACGCGGAATCGTACGGCTCGATTCGCAATTTCGCGCTCAAGCACGGCGACACGATTT
CCCCGAACCGCGATCTCGTCGCGCTCGGCTGCGCGAATCTCGTATCGGGGCTGCTGCACGGGATGCCTGTCGGCGCCGGC
TACTCGGCGACGTCGGCGAACGAGGCGGCGGGCGCGCAGACGCGCATGGCGGGCTTGTTCGCGGCCGCCGTGATCGCGCT
GATCGTCTGGCTGCTGCTGCCGCAGCTCGCGCGCATCCCCGAGCCCGTGCTCGCCGCGATCGTGATCTTCGCGGTCAGTC
ATTCTCTGCATCCCGAAGTGTTCCGGCCGTACTGGGCCTGGCATCGCGACCGGATCGTCGTGGTCGCCGCGCTCGCGGCC
GTGATCGTGCTCGGCGTGCTGCACGGCCTGCTCGCCGCGATCGGCGTGAGCCTGCTGCTGACGTTGCGGCAGTTGTCCGA
GCCGAACGTGAGCGTGCTCGGGCGGCTGCGCGAGAGCCACGATTTCGTCGACGTGTCGATGCACGAGGATGCAAAGCCGA
TTCCCGGCGTGCTGATCGTGCGGCCGGAAGCGCAACTGTTCTTCGCGAACGCGGAGCGCGTGCTGACCATGGCGCGGCGT
CTCGCGCGCGACGCGCAGCCGCCCGTGCACACGGTGATGCTGAGTCTCGAGGAGTCGCCCGATGTGGACGGCACGACGAT
CGAAGCGTTGAAGACGTTCGGTGCCGAGTGCGACGCGCGCGGCTGGCGTCTCGTGCTCGTGCGCCTGAAGCCGAACGTGC
TGCGCGTGCTGCAACGGGCGGCGGACGGGGCGCTGCGCGCGAATGCGCTGTCGGAGCTGAGCGTCGACGAAAGCCTGCAA
TCGCTCGCGGCGGGTGAGCCGCAGCGCGCGTGA

Upstream 100 bases:

>100_bases
CAGGAGGCGCGCTATCTGCCGGGCTGGTCCGGCGTGATCGCCGCGCCGCGCTGAGCACCGCGTCTTCGTTTGCACGACGG
GCAACGCTTACGGAGCGCGC

Downstream 100 bases:

>100_bases
CGCATCGACTCCCGACGCGGGGTGCCGGGTGCGCGTGTCCTGCGCTCGGGCGGGCGTTCGGCGCCCGCGTGCCGTTTGCG
GCATCGGCGAGCCGGGCCAT

Product: sulfate permease family protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MDLRSKHIDAPPQQAAHFASLDKPPAPRGRRAVLDALAGLSIAGLLIPEAVAYAGLASLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFVFAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QVPKVLDVRIHHGDTLRVVLDLLLGIPDCNVYSTALGATALAILFTLGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GAIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTISPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIVWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWAWHRDRIVVVAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRESHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLVLVRLKPNVLRVLQRAADGALRANALSELSVDESLQ
SLAAGEPQRA

Sequences:

>Translated_570_residues
MDLRSKHIDAPPQQAAHFASLDKPPAPRGRRAVLDALAGLSIAGLLIPEAVAYAGLASLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFVFAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QVPKVLDVRIHHGDTLRVVLDLLLGIPDCNVYSTALGATALAILFTLGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GAIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTISPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIVWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWAWHRDRIVVVAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRESHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLVLVRLKPNVLRVLQRAADGALRANALSELSVDESLQ
SLAAGEPQRA
>Mature_570_residues
MDLRSKHIDAPPQQAAHFASLDKPPAPRGRRAVLDALAGLSIAGLLIPEAVAYAGLASLPPQAGLIALVVGLVVYAIAGS
SRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVATTGILFVFAGAARLGGMSDFIARPVLRGFTFGLALTIVIK
QVPKVLDVRIHHGDTLRVVLDLLLGIPDCNVYSTALGATALAILFTLGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
GAIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTISPNRDLVALGCANLVSGLLHGMPVGAG
YSATSANEAAGAQTRMAGLFAAAVIALIVWLLLPQLARIPEPVLAAIVIFAVSHSLHPEVFRPYWAWHRDRIVVVAALAA
VIVLGVLHGLLAAIGVSLLLTLRQLSEPNVSVLGRLRESHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLVLVRLKPNVLRVLQRAADGALRANALSELSVDESLQ
SLAAGEPQRA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=491, Percent_Identity=25.050916496945, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI45827800, Length=491, Percent_Identity=25.050916496945, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94721255, Length=460, Percent_Identity=28.2608695652174, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI94721257, Length=460, Percent_Identity=28.2608695652174, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI94721253, Length=460, Percent_Identity=28.2608695652174, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI94721259, Length=460, Percent_Identity=28.2608695652174, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI269784651, Length=488, Percent_Identity=24.5901639344262, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI47131207, Length=492, Percent_Identity=27.2357723577236, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI20336272, Length=492, Percent_Identity=27.2357723577236, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI16418413, Length=482, Percent_Identity=23.0290456431535, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI217272867, Length=482, Percent_Identity=23.0290456431535, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557535, Length=487, Percent_Identity=22.9979466119097, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI45827802, Length=448, Percent_Identity=24.1071428571429, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4505697, Length=489, Percent_Identity=24.3353783231084, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI100913030, Length=497, Percent_Identity=22.5352112676056, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI16306483, Length=494, Percent_Identity=23.2793522267206, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI20336282, Length=494, Percent_Identity=23.2793522267206, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI65506789, Length=427, Percent_Identity=25.7611241217799, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI262206105, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206075, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206069, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI262206063, Length=264, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI16418457, Length=539, Percent_Identity=21.1502782931354, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI301601599, Length=539, Percent_Identity=21.1502782931354, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081859, Length=200, Percent_Identity=32, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551690, Length=553, Percent_Identity=25.8589511754069, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17566848, Length=430, Percent_Identity=25.3488372093023, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI86565215, Length=482, Percent_Identity=23.6514522821577, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI86564196, Length=474, Percent_Identity=22.1518987341772, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193203292, Length=487, Percent_Identity=22.5872689938398, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86564876, Length=521, Percent_Identity=20.9213051823417, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562578, Length=497, Percent_Identity=23.1388329979879, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325260, Length=497, Percent_Identity=23.943661971831, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319771, Length=476, Percent_Identity=21.218487394958, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6323121, Length=162, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24651449, Length=564, Percent_Identity=24.822695035461, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24649801, Length=579, Percent_Identity=23.6614853195164, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24666186, Length=510, Percent_Identity=23.1372549019608, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21358229, Length=557, Percent_Identity=24.5960502692998, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24663084, Length=552, Percent_Identity=24.4565217391304, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357695, Length=552, Percent_Identity=24.4565217391304, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647160, Length=496, Percent_Identity=23.991935483871, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19922482, Length=529, Percent_Identity=22.6843100189036, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355087, Length=496, Percent_Identity=24.1935483870968, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358633, Length=443, Percent_Identity=23.9277652370203, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI85815873, Length=448, Percent_Identity=22.7678571428571, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 60112; Mature: 60112

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50801 STAS ; PS00131 CARBOXYPEPT_SER_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRSKHIDAPPQQAAHFASLDKPPAPRGRRAVLDALAGLSIAGLLIPEAVAYAGLASLP
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PQAGLIALVVGLVVYAIAGSSRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
TTGILFVFAGAARLGGMSDFIARPVLRGFTFGLALTIVIKQVPKVLDVRIHHGDTLRVVL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHH
DLLLGIPDCNVYSTALGATALAILFTLGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
GAIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTISPNRDLV
EEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRMAGLFAAAVIALIVWLLLPQLARIP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVLAAIVIFAVSHSLHPEVFRPYWAWHRDRIVVVAALAAVIVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRQLSEPNVSVLGRLRESHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
HHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLVLVRLKPNVLRVLQRA
HHHCCCCCHHHHEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHH
ADGALRANALSELSVDESLQSLAAGEPQRA
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLRSKHIDAPPQQAAHFASLDKPPAPRGRRAVLDALAGLSIAGLLIPEAVAYAGLASLP
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PQAGLIALVVGLVVYAIAGSSRFAIVSATSSSAVVLAATVMSEAGPGAAAQLMLAAALVA
CCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
TTGILFVFAGAARLGGMSDFIARPVLRGFTFGLALTIVIKQVPKVLDVRIHHGDTLRVVL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHH
DLLLGIPDCNVYSTALGATALAILFTLGRRTRVPATLVVIVLGIAAGYWIDWHRYGIAVV
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
GAIDLQNLAFGMPVLGRSGWMQTAEFGFALMLILYAESYGSIRNFALKHGDTISPNRDLV
EEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
ALGCANLVSGLLHGMPVGAGYSATSANEAAGAQTRMAGLFAAAVIALIVWLLLPQLARIP
EHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EPVLAAIVIFAVSHSLHPEVFRPYWAWHRDRIVVVAALAAVIVLGVLHGLLAAIGVSLLL
HHHHHHHHHHHHHCCCCHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRQLSEPNVSVLGRLRESHDFVDVSMHEDAKPIPGVLIVRPEAQLFFANAERVLTMARR
HHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCEEEECCHHHHHHHHHH
LARDAQPPVHTVMLSLEESPDVDGTTIEALKTFGAECDARGWRLVLVRLKPNVLRVLQRA
HHHCCCCCHHHHEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHH
ADGALRANALSELSVDESLQSLAAGEPQRA
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]