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The map label for this gene is thiL [H]

Identifier: 83720486

GI number: 83720486

Start: 1332818

End: 1333819

Strand: Reverse

Name: thiL [H]

Synonym: BTH_I1188

Alternate gene names: 83720486

Gene position: 1333819-1332818 (Counterclockwise)

Preceding gene: 83720201

Following gene: 83719014

Centisome position: 35.02

GC content: 73.65

Gene sequence:

>1002_bases
GTGGCCCATTCTCCCCTCTCGGAATTCTCGTTGATCGACCGCTTCTTCGCGCGCCGCGCGAAAGGGCCGCACGCGCGCGC
CGCGCTCGGCATCGGCGACGACTGCGCGCTGCTTGCACCAGAACCGGGCAAGATGCTGGCGATTTCGACGGACATGCTGG
TCGAAGGCCGGCACTTCCTCGCCGACGTCGATCCGCGCGCGCTCGGCCACAAGACGCTCGCCGTCAATTTGTCCGACCTC
GCCGGGATGGGCGCCGCGCCGCGCGCGTTCACGCTCGCGTGTGCGCTGCCGCGCGCCGATGCCGACTGGCTCGACGCGTT
CTCCGACGGCCTCTTCGCGCTCGCGGACCGCCACGGCTGCGAGCTGATCGGCGGCGACACGACGAGCGGCCCACTCAACC
TGTGCGTCACCGTGTTCGGCGACGTCGCGTCCGACGCGGCGCTGCGTCGCGACGCCGCACGCGACGGCGACGACGTCTGG
GTATCCGGCACGCTCGGCGACGCGCGCGCCGGCCTCGGCGTGATCCGCGGCGAATGGCGCGCGGGCGAGCGCGAGGCGGC
CGCGTTCCGGCGCGCGCTCGAGTGGCCGCAGCCGCGCGTCGCGCTCGGCGTCGCGCTCGCGGGCATCGCGCATGCGGCGC
TCGACGTGTCCGATGGCCTCGCGGGCGATCTGCCGCACATCCTCGAGCGCTCGAACGTGCGCGCCGACGTGAACGTCGAC
GCGGTGCCCCGCTCGGCCGCGCTCGCGACGCTGCCCGCCGACGTGCAGCGCCGCTGCATGCTCGAAGGCGGCGACGACTA
CGAACTGTGCTTCACGGCCGCGCCGTCCGCGCGCACCGCGATCGACGCGGCCGGCGCGCGCGCGGGCGTGGCCGTCACGC
GGATCGGTACAATACGCGGCTTGTCCGCGCCGACGGACGCGCGCGCCGTCACGTGGCGCGACGCGTCGGGCGCGCCGCTT
TCGCTCACGCTGCACGGTTTCGATCATTTCCATGTCAACTGA

Upstream 100 bases:

>100_bases
AAACGCCACGAATCGGCCGCGCGCAGGCCGCCGCGCCGCCTGGCCGCGGCCCGAAGCGCCTTACAATGAACGTCATCTCA
ACGCTCGGACATCCGCGCCC

Downstream 100 bases:

>100_bases
CCCGACGCCCCGTCCGGCCGACTCCGCCGGCCAGCCCGGCCAGGCGCCCATGCCGGCGCCCTCGCCCGCAACGCAGCAGG
ACCCGCAGAAGATCGCGCGC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAHSPLSEFSLIDRFFARRAKGPHARAALGIGDDCALLAPEPGKMLAISTDMLVEGRHFLADVDPRALGHKTLAVNLSDL
AGMGAAPRAFTLACALPRADADWLDAFSDGLFALADRHGCELIGGDTTSGPLNLCVTVFGDVASDAALRRDAARDGDDVW
VSGTLGDARAGLGVIRGEWRAGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVNVD
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRGLSAPTDARAVTWRDASGAPL
SLTLHGFDHFHVN

Sequences:

>Translated_333_residues
MAHSPLSEFSLIDRFFARRAKGPHARAALGIGDDCALLAPEPGKMLAISTDMLVEGRHFLADVDPRALGHKTLAVNLSDL
AGMGAAPRAFTLACALPRADADWLDAFSDGLFALADRHGCELIGGDTTSGPLNLCVTVFGDVASDAALRRDAARDGDDVW
VSGTLGDARAGLGVIRGEWRAGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVNVD
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRGLSAPTDARAVTWRDASGAPL
SLTLHGFDHFHVN
>Mature_332_residues
AHSPLSEFSLIDRFFARRAKGPHARAALGIGDDCALLAPEPGKMLAISTDMLVEGRHFLADVDPRALGHKTLAVNLSDLA
GMGAAPRAFTLACALPRADADWLDAFSDGLFALADRHGCELIGGDTTSGPLNLCVTVFGDVASDAALRRDAARDGDDVWV
SGTLGDARAGLGVIRGEWRAGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVNVDA
VPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRGLSAPTDARAVTWRDASGAPLS
LTLHGFDHFHVN

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=330, Percent_Identity=43.9393939393939, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34792; Mature: 34660

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSPLSEFSLIDRFFARRAKGPHARAALGIGDDCALLAPEPGKMLAISTDMLVEGRHFL
CCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCEEEEECCCEECCCHHE
ADVDPRALGHKTLAVNLSDLAGMGAAPRAFTLACALPRADADWLDAFSDGLFALADRHGC
ECCCCHHCCCEEEEEEHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCEEECCCCCC
ELIGGDTTSGPLNLCVTVFGDVASDAALRRDAARDGDDVWVSGTLGDARAGLGVIRGEWR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCEEEECCCC
AGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVNVD
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEECCCC
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRG
CCCCCHHEEECCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCEEEEEEEHCCC
LSAPTDARAVTWRDASGAPLSLTLHGFDHFHVN
CCCCCCCCEEEEECCCCCEEEEEEECCEEEECC
>Mature Secondary Structure 
AHSPLSEFSLIDRFFARRAKGPHARAALGIGDDCALLAPEPGKMLAISTDMLVEGRHFL
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCEEEEECCCEECCCHHE
ADVDPRALGHKTLAVNLSDLAGMGAAPRAFTLACALPRADADWLDAFSDGLFALADRHGC
ECCCCHHCCCEEEEEEHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCEEECCCCCC
ELIGGDTTSGPLNLCVTVFGDVASDAALRRDAARDGDDVWVSGTLGDARAGLGVIRGEWR
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCEEEECCCC
AGEREAAAFRRALEWPQPRVALGVALAGIAHAALDVSDGLAGDLPHILERSNVRADVNVD
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEECCCC
AVPRSAALATLPADVQRRCMLEGGDDYELCFTAAPSARTAIDAAGARAGVAVTRIGTIRG
CCCCCHHEEECCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCEEEEEEEHCCC
LSAPTDARAVTWRDASGAPLSLTLHGFDHFHVN
CCCCCCCCEEEEECCCCCEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]