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The map label for this gene is degP [H]

Identifier: 83720454

GI number: 83720454

Start: 775210

End: 776697

Strand: Direct

Name: degP [H]

Synonym: BTH_I0675

Alternate gene names: 83720454

Gene position: 775210-776697 (Clockwise)

Preceding gene: 83721403

Following gene: 83718734

Centisome position: 20.35

GC content: 68.35

Gene sequence:

>1488_bases
ATGACTACCCGAATCCTTGCGCGTGGCGCAGTTGCCGTGGCCGTCGCCGCGGCGTTGTCGGCGGGGTATGTGGCGGGCAC
CCGCCATGCGGAACCGCAGATCATCACACCGGCCGTCGCCGCGCTGATGCCGGCCGAGGCAGCCGCGAAGACGGGCATCC
CCGACTTTTCCGGCCTGGTCGAGACCTACGGGCCGGCCGTCGTGAACATCAGCGCGAAGCACGTCGTGCAGCGCGTCGCG
CAGCGCCGCGCAGCGCCGCAATTGCCGATCGATCCGGAAGATCCGTTCTACCAATTCTTCCGACATTTCTACGGGCAGGT
TCCCGGGATGGGCGGTGGCCGCCAGCCGCAGCCGGACGACCAGCCGAGCACGAGCCTGGGCTCCGGGTTCATCATCAGCG
CGGACGGGTATATCCTGACCAACGCGCACGTGATCGACGGCGCGAACGTCGTCACGGTGAAGCTCACCGACAAGCGCGAG
TACAAGGCGAAGGTCGTCGGCACCGACAAGCAATCCGACGTCGCGGTGCTGAAGATTGACGCGTCGGGCCTGCCGACCGT
GAAGATCGGCGATCCGGCGCAGAGCAAGGTCGGCCAGTGGGTCGTCGCGATCGGTTCGCCGTACGGGTTCGACAACACGG
TCACGTCGGGCATCATCAGCGCGAAGTCGCGCGCGCTGCCCGACGAGAACTACACGCCGTTCATCCAGACCGACGTGCCG
GTGAACCCCGGCAACTCGGGCGGTCCGCTCTTCAACCTGAACGGCGAGGTGATCGGCATCAACTCGATGATCTACTCGCA
GACGGGCGGCTTCCAGGGCCTGTCGTTCGCGATCCCGATCAACGAGGCGATGAAGGTGAAGGACGAGCTCGTGAAGACGG
GCCACGTGAGCCGCGGCCGGCTCGGCGTCGCGGTGCAGGGGCTCAACCAGACGCTCGCGAGCTCGTTCGGCCTGCAAAAG
CCCGACGGCGCGCTCGTCAGCTCGGTCGACCCGAAGGGGCCGGCCGCGAAGGCGGGGCTGCAGCCGGGCGACGTGATCCT
CGCGGTCGACGGCGTGCCGGTTCAGGACTCGACGACGTTGCCCGCGCAGATCGCGAGCATGAAGCCGGGCACGAAGGCCG
ACCTGCAGATCTGGCGAGACAAGTCGAAGAAGACAGTGTCGGTGACGCTTGCGTCGCTGGCCGACGATCAGGCGAAGGCG
GGCGCCGACGAGCCCGTCGAGCAGGGACGCCTGGGCGTCGCGGTGCGGCCGCTTTTGCCGCGCGAGCGCAACGGCACGTC
GCTCACGCACGGCCTCGTCGTCCAGCAGTCGACGGGCCCCGCCGCAAGCGCGGGCATCCAGCCGGGCGACGTGATCCTCG
CGGTGAACGGGCGGCCCGTCACGAGCGCCGAACAATTGCGCGACGCGGTCAAGCGCGCGGGCAACAGCCTTGCGCTGCTG
ATCCAGCGCGACGACGCCCAGATTTTCGTGCCGGTCGATCTGGGCTGA

Upstream 100 bases:

>100_bases
CTCTCGCTTACCCTATCCGTTTGGCGGTTCCCGAAGCCGATTAAGCCTGCTTTAAGTCAGGGTCGCTACGCTGCAAACGG
TTAGACGAGGAGAACGATCG

Downstream 100 bases:

>100_bases
GCCGGGGCGCATCGCACCCGGCGCGACGGGCGGGCCGGCGCGGCGGCGCGGCGCGCGGGCGGCAAGACGGCCGTCCGCCT
CATCGCGCGGCCTGCCTTGC

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTTRILARGAVAVAVAAALSAGYVAGTRHAEPQIITPAVAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVQRVA
QRRAAPQLPIDPEDPFYQFFRHFYGQVPGMGGGRQPQPDDQPSTSLGSGFIISADGYILTNAHVIDGANVVTVKLTDKRE
YKAKVVGTDKQSDVAVLKIDASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVP
VNPGNSGGPLFNLNGEVIGINSMIYSQTGGFQGLSFAIPINEAMKVKDELVKTGHVSRGRLGVAVQGLNQTLASSFGLQK
PDGALVSSVDPKGPAAKAGLQPGDVILAVDGVPVQDSTTLPAQIASMKPGTKADLQIWRDKSKKTVSVTLASLADDQAKA
GADEPVEQGRLGVAVRPLLPRERNGTSLTHGLVVQQSTGPAASAGIQPGDVILAVNGRPVTSAEQLRDAVKRAGNSLALL
IQRDDAQIFVPVDLG

Sequences:

>Translated_495_residues
MTTRILARGAVAVAVAAALSAGYVAGTRHAEPQIITPAVAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVQRVA
QRRAAPQLPIDPEDPFYQFFRHFYGQVPGMGGGRQPQPDDQPSTSLGSGFIISADGYILTNAHVIDGANVVTVKLTDKRE
YKAKVVGTDKQSDVAVLKIDASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVP
VNPGNSGGPLFNLNGEVIGINSMIYSQTGGFQGLSFAIPINEAMKVKDELVKTGHVSRGRLGVAVQGLNQTLASSFGLQK
PDGALVSSVDPKGPAAKAGLQPGDVILAVDGVPVQDSTTLPAQIASMKPGTKADLQIWRDKSKKTVSVTLASLADDQAKA
GADEPVEQGRLGVAVRPLLPRERNGTSLTHGLVVQQSTGPAASAGIQPGDVILAVNGRPVTSAEQLRDAVKRAGNSLALL
IQRDDAQIFVPVDLG
>Mature_494_residues
TTRILARGAVAVAVAAALSAGYVAGTRHAEPQIITPAVAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVQRVAQ
RRAAPQLPIDPEDPFYQFFRHFYGQVPGMGGGRQPQPDDQPSTSLGSGFIISADGYILTNAHVIDGANVVTVKLTDKREY
KAKVVGTDKQSDVAVLKIDASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVPV
NPGNSGGPLFNLNGEVIGINSMIYSQTGGFQGLSFAIPINEAMKVKDELVKTGHVSRGRLGVAVQGLNQTLASSFGLQKP
DGALVSSVDPKGPAAKAGLQPGDVILAVDGVPVQDSTTLPAQIASMKPGTKADLQIWRDKSKKTVSVTLASLADDQAKAG
ADEPVEQGRLGVAVRPLLPRERNGTSLTHGLVVQQSTGPAASAGIQPGDVILAVNGRPVTSAEQLRDAVKRAGNSLALLI
QRDDAQIFVPVDLG

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=241, Percent_Identity=38.1742738589212, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI22129776, Length=265, Percent_Identity=36.6037735849057, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI7019477, Length=294, Percent_Identity=36.3945578231293, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI24308541, Length=251, Percent_Identity=35.4581673306773, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1786356, Length=371, Percent_Identity=40.9703504043127, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1789629, Length=491, Percent_Identity=35.6415478615071, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=39.8523985239852, Blast_Score=189, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24646839, Length=295, Percent_Identity=34.9152542372881, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51412; Mature: 51281

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRILARGAVAVAVAAALSAGYVAGTRHAEPQIITPAVAALMPAEAAAKTGIPDFSGLV
CCCEEECCCHHHHHHHHHHHCCCEECCCCCCCCEECHHHHHHCCHHHHHHCCCCCHHHHH
ETYGPAVVNISAKHVVQRVAQRRAAPQLPIDPEDPFYQFFRHFYGQVPGMGGGRQPQPDD
HHCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
QPSTSLGSGFIISADGYILTNAHVIDGANVVTVKLTDKREYKAKVVGTDKQSDVAVLKID
CCCCCCCCCEEEECCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEC
ASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVP
CCCCCEEEECCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCC
VNPGNSGGPLFNLNGEVIGINSMIYSQTGGFQGLSFAIPINEAMKVKDELVKTGHVSRGR
CCCCCCCCCEEECCCCEEEECCEEEECCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCC
LGVAVQGLNQTLASSFGLQKPDGALVSSVDPKGPAAKAGLQPGDVILAVDGVPVQDSTTL
EEEEEECHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCC
PAQIASMKPGTKADLQIWRDKSKKTVSVTLASLADDQAKAGADEPVEQGRLGVAVRPLLP
CHHHHCCCCCCCCHHHEEECCCCCEEEEEEEHHCCCHHHCCCCCCHHCCCCCEEEECCCC
RERNGTSLTHGLVVQQSTGPAASAGIQPGDVILAVNGRPVTSAEQLRDAVKRAGNSLALL
CCCCCCCEEEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEE
IQRDDAQIFVPVDLG
EEECCCEEEEEECCC
>Mature Secondary Structure 
TTRILARGAVAVAVAAALSAGYVAGTRHAEPQIITPAVAALMPAEAAAKTGIPDFSGLV
CCEEECCCHHHHHHHHHHHCCCEECCCCCCCCEECHHHHHHCCHHHHHHCCCCCHHHHH
ETYGPAVVNISAKHVVQRVAQRRAAPQLPIDPEDPFYQFFRHFYGQVPGMGGGRQPQPDD
HHCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
QPSTSLGSGFIISADGYILTNAHVIDGANVVTVKLTDKREYKAKVVGTDKQSDVAVLKID
CCCCCCCCCEEEECCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEC
ASGLPTVKIGDPAQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPDENYTPFIQTDVP
CCCCCEEEECCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCC
VNPGNSGGPLFNLNGEVIGINSMIYSQTGGFQGLSFAIPINEAMKVKDELVKTGHVSRGR
CCCCCCCCCEEECCCCEEEECCEEEECCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCC
LGVAVQGLNQTLASSFGLQKPDGALVSSVDPKGPAAKAGLQPGDVILAVDGVPVQDSTTL
EEEEEECHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCC
PAQIASMKPGTKADLQIWRDKSKKTVSVTLASLADDQAKAGADEPVEQGRLGVAVRPLLP
CHHHHCCCCCCCCHHHEEECCCCCEEEEEEEHHCCCHHHCCCCCCHHCCCCCEEEECCCC
RERNGTSLTHGLVVQQSTGPAASAGIQPGDVILAVNGRPVTSAEQLRDAVKRAGNSLALL
CCCCCCCEEEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEE
IQRDDAQIFVPVDLG
EEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]