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The map label for this gene is pepQ [H]

Identifier: 83720395

GI number: 83720395

Start: 3364426

End: 3366240

Strand: Reverse

Name: pepQ [H]

Synonym: BTH_I2927

Alternate gene names: 83720395

Gene position: 3366240-3364426 (Counterclockwise)

Preceding gene: 83719631

Following gene: 83721104

Centisome position: 88.37

GC content: 71.74

Gene sequence:

>1815_bases
ATGAATGCCCGACTTCCCGATCCGTCGCCCGTGCCGGCGCGTCTTGCCCTGTTGCGCGGCGCGATGACGCGCGAGGATCT
GGCCGCCTACGTGGTGCCGTCCGCCGATCCCCATTTGTCCGAGTATCTGCCCGAGCGCTGGCAGGCGCGGCAATGGCTGT
CGGGCTTCACCGGCTCGGTCGGCACGCTTGTCGTGACCGCCGATTTCGCGGGCCTCTGGGTCGACAGCCGCTACTGGGTG
CAGGCCGAGGCGCAGCTCGCGGGCACGGGCGTCGCGCTGATGAAGATGGCGGGCGGCCAGCAGACGCAGCCGCACGTCGA
ATGGCTCGCCGAGCACGTGCCCGAGGGCACGACGGTCGGCGTGGACGGCGCGGTGCTCGGCGTCGCGGCGGCGCGCGCGC
TCACGTCCGCGCTCACTCCGCGCGGCATCGTGCTGCGCACCGATCTCGACCTGCTCGACGCGATCTGGCCGCAGCGCCCG
TCGCTGCCCGGCGACGCGGTGTTCGAGCACGCGGCGCCGCAGGCAGACACGGCCCGCGCGGGCAAGCTCGCGCAGGTGCG
TCGCGCGATGCACGAGCAGGGCGCGCAGTGGCATTTCGTGTCGACGCTCGACGATCTCGCCTGGCTCTTCAACCTGCGCG
GCGCCGACGTCAACTACAACCCGGTGTTCGTCGCGCACGCGCTCGTCGGCCTCGAGCGCGCGACGCTGTTCGTCGCCGAC
GGCAAGGTGTCGCCCGAGCTCGCGACGTCGCTCGCGCAGGACGGCGTCGACGTGAAGCCGTACGACGCCGCGGCCGCGGC
GCTCGCCGCGCTGCCCGAGGGCGCGGGGCTGCTGATCGATCCGCGCCGCGTCACGTACGGGCTGCTGCAGGCGGTGCCGC
AGCAGGTGCGCGTGATCGAGGCGGTGAATCCGTCGACGTTCGCGAAATCGCGCAAGACGCCCGCCGAGATCGAGCATGTG
CGCGCGACGATGGAGCTCGACGGCGCGGCGCTCGCCGAATTCTTCGCGTGGTTCGAGGGCGCGCTCGGCCGCGAGACGAT
CACCGAGCTGACGATCGACGAGCAGCTCACCGCCGCGCGCGCGCGCCGGCCGGGCTACGTGTCGCCGAGCTTCGCGACGA
TCGCGGGCTTCAACGCGAACGGCGCGATGCCGCACTATCGCGCGACGTCCGCCGCGCACGCGACGATCGAAGGCGACGGC
TTGCTGCTCGTCGATTCGGGCGGCCAGTATCTGAGCGGGACGACCGACATCACGCGCGTCGTGCCGGTCGGCGCGATCGG
CGACGCGCACCGGCGCGACTTCACGATCGTGCTGAAGGCGATGATGGCGCTGTCGCGCGCGCGCTTCCCGCGCGGCATCC
GCTCGCCGATGCTCGACGCGATCGCGCGCGCGCCGATGTGGGCGGCCGGGCTCGACTACGGGCACGGCACGGGGCACGGC
GTCGGCTATTTCCTGAACGTCCACGAAGGGCCGCAGGTGATCTCGCACCATGCGCCCGCCGAGCCTTACACGGCGATGGA
AGAGGGGATGATCACGTCGATCGAGCCCGGCGTGTACCGGCCGGGCAAGTGGGGCGTGCGCATCGAGAATCTCGTCGTGA
ACCGCGCGGCGGGCCAGACCGAGTTCGGCGATTTCCTCGAATTCGAGACGCTGACGCTCTGCCCGATCGACACGCGCTGC
GTGTTGCCCGCGCTTCTCGACGGCGACGAGCGCGCATGGCTGAACGCGTATCACGCGACGGTGCGCGAGCGGGTCGGCAA
GCACGTGTCGGGCGACGCGAAGGCGTGGCTCGACGCGCGCACGCAGCCGATCTGA

Upstream 100 bases:

>100_bases
CGAGACGCTCGAATGGCCGGTCTGCACCGCCGCCGCGCTTCTCGCCGTTGCCGTGACGGTGGGCCTGTTGGCCCGCCGCT
GAACGTTTGCAGGTGAAATC

Downstream 100 bases:

>100_bases
CGGACGCGCGGCCGCCGGCGTCGCCCGTCGCCGGATCGCCGGCCGCGGGTGCCGGCGGGCGGGGCGAACGATCGAACGAT
AACAACGGAGGGCGGCATAT

Product: peptidase, M24 family protein

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MNARLPDPSPVPARLALLRGAMTREDLAAYVVPSADPHLSEYLPERWQARQWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAQLAGTGVALMKMAGGQQTQPHVEWLAEHVPEGTTVGVDGAVLGVAAARALTSALTPRGIVLRTDLDLLDAIWPQRP
SLPGDAVFEHAAPQADTARAGKLAQVRRAMHEQGAQWHFVSTLDDLAWLFNLRGADVNYNPVFVAHALVGLERATLFVAD
GKVSPELATSLAQDGVDVKPYDAAAAALAALPEGAGLLIDPRRVTYGLLQAVPQQVRVIEAVNPSTFAKSRKTPAEIEHV
RATMELDGAALAEFFAWFEGALGRETITELTIDEQLTAARARRPGYVSPSFATIAGFNANGAMPHYRATSAAHATIEGDG
LLLVDSGGQYLSGTTDITRVVPVGAIGDAHRRDFTIVLKAMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHHAPAEPYTAMEEGMITSIEPGVYRPGKWGVRIENLVVNRAAGQTEFGDFLEFETLTLCPIDTRC
VLPALLDGDERAWLNAYHATVRERVGKHVSGDAKAWLDARTQPI

Sequences:

>Translated_604_residues
MNARLPDPSPVPARLALLRGAMTREDLAAYVVPSADPHLSEYLPERWQARQWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAQLAGTGVALMKMAGGQQTQPHVEWLAEHVPEGTTVGVDGAVLGVAAARALTSALTPRGIVLRTDLDLLDAIWPQRP
SLPGDAVFEHAAPQADTARAGKLAQVRRAMHEQGAQWHFVSTLDDLAWLFNLRGADVNYNPVFVAHALVGLERATLFVAD
GKVSPELATSLAQDGVDVKPYDAAAAALAALPEGAGLLIDPRRVTYGLLQAVPQQVRVIEAVNPSTFAKSRKTPAEIEHV
RATMELDGAALAEFFAWFEGALGRETITELTIDEQLTAARARRPGYVSPSFATIAGFNANGAMPHYRATSAAHATIEGDG
LLLVDSGGQYLSGTTDITRVVPVGAIGDAHRRDFTIVLKAMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHHAPAEPYTAMEEGMITSIEPGVYRPGKWGVRIENLVVNRAAGQTEFGDFLEFETLTLCPIDTRC
VLPALLDGDERAWLNAYHATVRERVGKHVSGDAKAWLDARTQPI
>Mature_604_residues
MNARLPDPSPVPARLALLRGAMTREDLAAYVVPSADPHLSEYLPERWQARQWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAQLAGTGVALMKMAGGQQTQPHVEWLAEHVPEGTTVGVDGAVLGVAAARALTSALTPRGIVLRTDLDLLDAIWPQRP
SLPGDAVFEHAAPQADTARAGKLAQVRRAMHEQGAQWHFVSTLDDLAWLFNLRGADVNYNPVFVAHALVGLERATLFVAD
GKVSPELATSLAQDGVDVKPYDAAAAALAALPEGAGLLIDPRRVTYGLLQAVPQQVRVIEAVNPSTFAKSRKTPAEIEHV
RATMELDGAALAEFFAWFEGALGRETITELTIDEQLTAARARRPGYVSPSFATIAGFNANGAMPHYRATSAAHATIEGDG
LLLVDSGGQYLSGTTDITRVVPVGAIGDAHRRDFTIVLKAMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHHAPAEPYTAMEEGMITSIEPGVYRPGKWGVRIENLVVNRAAGQTEFGDFLEFETLTLCPIDTRC
VLPALLDGDERAWLNAYHATVRERVGKHVSGDAKAWLDARTQPI

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=631, Percent_Identity=35.9746434231379, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI264681565, Length=631, Percent_Identity=34.7068145800317, Blast_Score=342, Evalue=5e-94,
Organism=Homo sapiens, GI93141226, Length=605, Percent_Identity=33.2231404958678, Blast_Score=332, Evalue=8e-91,
Organism=Escherichia coli, GI1788728, Length=230, Percent_Identity=32.1739130434783, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=596, Percent_Identity=31.8791946308725, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI25149105, Length=629, Percent_Identity=27.8219395866455, Blast_Score=238, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6322999, Length=653, Percent_Identity=29.8621745788668, Blast_Score=283, Evalue=8e-77,
Organism=Drosophila melanogaster, GI17137632, Length=595, Percent_Identity=33.6134453781513, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI161078230, Length=610, Percent_Identity=26.5573770491803, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI21357287, Length=610, Percent_Identity=26.5573770491803, Blast_Score=231, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 64959; Mature: 64959

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARLPDPSPVPARLALLRGAMTREDLAAYVVPSADPHLSEYLPERWQARQWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GTLVVTADFAGLWVDSRYWVQAEAQLAGTGVALMKMAGGQQTQPHVEWLAEHVPEGTTVG
EEEEEEECCCEEEECCEEEEEEECHHCCCCCEEHHHCCCCCCCHHHHHHHHHCCCCCEEC
VDGAVLGVAAARALTSALTPRGIVLRTDLDLLDAIWPQRPSLPGDAVFEHAAPQADTARA
CCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHC
GKLAQVRRAMHEQGAQWHFVSTLDDLAWLFNLRGADVNYNPVFVAHALVGLERATLFVAD
CHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEEEEEC
GKVSPELATSLAQDGVDVKPYDAAAAALAALPEGAGLLIDPRRVTYGLLQAVPQQVRVIE
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
AVNPSTFAKSRKTPAEIEHVRATMELDGAALAEFFAWFEGALGRETITELTIDEQLTAAR
CCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARRPGYVSPSFATIAGFNANGAMPHYRATSAAHATIEGDGLLLVDSGGQYLSGTTDITRV
HCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCEECCCCCHHEE
VPVGAIGDAHRRDFTIVLKAMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EEECCCCCCHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VGYFLNVHEGPQVISHHAPAEPYTAMEEGMITSIEPGVYRPGKWGVRIENLVVNRAAGQT
EEEEEEECCCCHHHHCCCCCCCCHHHHCCCEEECCCCCCCCCCCCCEEEHEEEECCCCCC
EFGDFLEFETLTLCPIDTRCVLPALLDGDERAWLNAYHATVRERVGKHVSGDAKAWLDAR
CCCCHHCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC
>Mature Secondary Structure
MNARLPDPSPVPARLALLRGAMTREDLAAYVVPSADPHLSEYLPERWQARQWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GTLVVTADFAGLWVDSRYWVQAEAQLAGTGVALMKMAGGQQTQPHVEWLAEHVPEGTTVG
EEEEEEECCCEEEECCEEEEEEECHHCCCCCEEHHHCCCCCCCHHHHHHHHHCCCCCEEC
VDGAVLGVAAARALTSALTPRGIVLRTDLDLLDAIWPQRPSLPGDAVFEHAAPQADTARA
CCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHC
GKLAQVRRAMHEQGAQWHFVSTLDDLAWLFNLRGADVNYNPVFVAHALVGLERATLFVAD
CHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEEEEEC
GKVSPELATSLAQDGVDVKPYDAAAAALAALPEGAGLLIDPRRVTYGLLQAVPQQVRVIE
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
AVNPSTFAKSRKTPAEIEHVRATMELDGAALAEFFAWFEGALGRETITELTIDEQLTAAR
CCCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARRPGYVSPSFATIAGFNANGAMPHYRATSAAHATIEGDGLLLVDSGGQYLSGTTDITRV
HCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCEECCCCCHHEE
VPVGAIGDAHRRDFTIVLKAMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EEECCCCCCHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
VGYFLNVHEGPQVISHHAPAEPYTAMEEGMITSIEPGVYRPGKWGVRIENLVVNRAAGQT
EEEEEEECCCCHHHHCCCCCCCCHHHHCCCEEECCCCCCCCCCCCCEEEHEEEECCCCCC
EFGDFLEFETLTLCPIDTRCVLPALLDGDERAWLNAYHATVRERVGKHVSGDAKAWLDAR
CCCCHHCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]